Rattus norvegicus

57 known processes

Hspg2

heparan sulfate proteoglycan 2

(Aliases: Per)

Hspg2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
g protein coupled receptor signaling pathway GO:0007186 242 0.112
gland development GO:0048732 155 0.085
oxoacid metabolic process GO:0043436 290 0.085
transcription from rna polymerase ii promoter GO:0006366 252 0.080
action potential GO:0001508 54 0.068
neurological system process GO:0050877 219 0.058
response to peptide GO:1901652 292 0.055
cellular divalent inorganic cation homeostasis GO:0072503 162 0.054
neuron differentiation GO:0030182 368 0.054
cellular calcium ion homeostasis GO:0006874 160 0.054
regulation of phosphate metabolic process GO:0019220 349 0.053
positive regulation of cellular biosynthetic process GO:0031328 295 0.050
macromolecular complex subunit organization GO:0043933 339 0.050
cellular cation homeostasis GO:0030003 180 0.049
regulation of protein phosphorylation GO:0001932 183 0.049
regulation of phosphorus metabolic process GO:0051174 349 0.049
programmed cell death GO:0012501 392 0.049
ion transmembrane transport GO:0034220 365 0.046
cation transport GO:0006812 382 0.046
positive regulation of phosphorus metabolic process GO:0010562 262 0.046
regulation of transcription dna templated GO:0006355 374 0.045
response to nutrient GO:0007584 248 0.044
cellular response to endogenous stimulus GO:0071495 377 0.044
regulation of signal transduction GO:0009966 318 0.044
nucleic acid templated transcription GO:0097659 379 0.043
regulation of cell differentiation GO:0045595 320 0.042
regulation of hormone levels GO:0010817 187 0.042
anatomical structure morphogenesis GO:0009653 298 0.042
regulation of catalytic activity GO:0050790 304 0.042
homeostatic process GO:0042592 331 0.041
central nervous system development GO:0007417 311 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.041
protein heterooligomerization GO:0051291 89 0.041
positive regulation of cell communication GO:0010647 271 0.040
positive regulation of phosphate metabolic process GO:0045937 262 0.038
sensory perception GO:0007600 101 0.038
divalent inorganic cation homeostasis GO:0072507 165 0.037
synaptic transmission GO:0007268 235 0.037
cellular amino acid metabolic process GO:0006520 107 0.037
organic acid metabolic process GO:0006082 292 0.037
regulation of cellular localization GO:0060341 263 0.037
response to wounding GO:0009611 254 0.036
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.036
cytosolic calcium ion homeostasis GO:0051480 140 0.036
carboxylic acid metabolic process GO:0019752 289 0.036
metal ion transport GO:0030001 289 0.036
nucleobase containing small molecule metabolic process GO:0055086 316 0.036
rhythmic process GO:0048511 156 0.036
carbohydrate derivative metabolic process GO:1901135 346 0.035
regulation of multicellular organismal development GO:2000026 376 0.035
protein phosphorylation GO:0006468 345 0.035
regulation of membrane potential GO:0042391 110 0.035
response to nutrient levels GO:0031667 370 0.035
transmembrane transport GO:0055085 412 0.035
macromolecular complex assembly GO:0065003 273 0.034
neuron development GO:0048666 286 0.034
cellular response to nitrogen compound GO:1901699 210 0.034
chemical homeostasis GO:0048878 292 0.034
response to peptide hormone GO:0043434 278 0.034
liver development GO:0001889 90 0.034
transcription dna templated GO:0006351 377 0.033
response to vitamin GO:0033273 131 0.033
cellular homeostasis GO:0019725 252 0.032
metal ion homeostasis GO:0055065 186 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.032
protein complex subunit organization GO:0071822 302 0.032
organonitrogen compound biosynthetic process GO:1901566 167 0.032
regulation of programmed cell death GO:0043067 341 0.031
lipid metabolic process GO:0006629 283 0.031
negative regulation of signaling GO:0023057 157 0.031
regulation of neurogenesis GO:0050767 247 0.030
intracellular signal transduction GO:0035556 314 0.030
calcium ion homeostasis GO:0055074 162 0.030
positive regulation of biosynthetic process GO:0009891 319 0.030
positive regulation of signaling GO:0023056 270 0.030
multi organism reproductive process GO:0044703 262 0.030
neuron projection development GO:0031175 273 0.029
response to extracellular stimulus GO:0009991 380 0.029
cell projection organization GO:0030030 302 0.029
negative regulation of metabolic process GO:0009892 331 0.029
regulation of molecular function GO:0065009 398 0.029
protein complex biogenesis GO:0070271 263 0.028
brain development GO:0007420 247 0.028
regulation of cell development GO:0060284 263 0.028
cellular chemical homeostasis GO:0055082 247 0.028
anterior posterior pattern specification GO:0009952 1 0.028
apoptotic process GO:0006915 381 0.028
negative regulation of cell death GO:0060548 229 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.028
reproductive process GO:0022414 372 0.028
regulation of apoptotic process GO:0042981 335 0.028
hepaticobiliary system development GO:0061008 90 0.027
single organism biosynthetic process GO:0044711 342 0.027
regulation of secretion GO:0051046 224 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
positive regulation of phosphorylation GO:0042327 177 0.027
regulation of rna metabolic process GO:0051252 391 0.027
amine metabolic process GO:0009308 38 0.027
cellular component assembly GO:0022607 360 0.027
cellular component biogenesis GO:0044085 368 0.027
cellular response to organic cyclic compound GO:0071407 202 0.027
head development GO:0060322 247 0.026
ribonucleotide metabolic process GO:0009259 231 0.026
heart morphogenesis GO:0003007 3 0.026
positive regulation of cell proliferation GO:0008284 249 0.026
purine ribonucleotide biosynthetic process GO:0009152 81 0.026
response to inorganic substance GO:0010035 377 0.026
secretion GO:0046903 307 0.026
regulation of protein modification process GO:0031399 194 0.026
sequestering of calcium ion GO:0051208 8 0.025
negative regulation of cellular metabolic process GO:0031324 281 0.025
regulation of rna biosynthetic process GO:2001141 381 0.025
cellular response to organonitrogen compound GO:0071417 197 0.025
cell cycle GO:0007049 101 0.025
cell cell signaling GO:0007267 335 0.025
response to growth factor GO:0070848 189 0.025
response to ethanol GO:0045471 162 0.025
regulation of cellular protein metabolic process GO:0032268 267 0.025
cellular ion homeostasis GO:0006873 184 0.025
cation homeostasis GO:0055080 195 0.025
sequestering of metal ion GO:0051238 9 0.025
response to oxidative stress GO:0006979 186 0.024
cellular metal ion homeostasis GO:0006875 172 0.024
positive regulation of nucleic acid templated transcription GO:1903508 197 0.024
cyclic nucleotide metabolic process GO:0009187 80 0.024
positive regulation of protein phosphorylation GO:0001934 135 0.024
regulation of neuron differentiation GO:0045664 208 0.024
response to acid chemical GO:0001101 222 0.024
organophosphate biosynthetic process GO:0090407 143 0.024
cellular amine metabolic process GO:0044106 38 0.023
positive regulation of rna biosynthetic process GO:1902680 197 0.023
regulation of protein metabolic process GO:0051246 289 0.023
ribonucleotide biosynthetic process GO:0009260 85 0.023
regeneration GO:0031099 163 0.023
positive regulation of molecular function GO:0044093 230 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
positive regulation of protein metabolic process GO:0051247 178 0.023
reproduction GO:0000003 245 0.023
neuronal action potential GO:0019228 35 0.022
maintenance of location GO:0051235 17 0.022
response to glucocorticoid GO:0051384 223 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
ion homeostasis GO:0050801 212 0.022
neuron death GO:0070997 127 0.022
inorganic cation transmembrane transport GO:0098662 202 0.022
rna biosynthetic process GO:0032774 380 0.022
halogenated hydrocarbon metabolic process GO:0042197 4 0.022
nucleoside phosphate biosynthetic process GO:1901293 102 0.022
protein homooligomerization GO:0051260 91 0.022
carboxylic acid transport GO:0046942 115 0.021
anion transport GO:0006820 178 0.021
nucleotide metabolic process GO:0009117 279 0.021
positive regulation of signal transduction GO:0009967 175 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
regulation of ion transport GO:0043269 245 0.021
positive regulation of apoptotic process GO:0043065 154 0.021
cellular response to hormone stimulus GO:0032870 247 0.021
tissue development GO:0009888 252 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
single organism intracellular transport GO:1902582 166 0.021
embryonic pattern specification GO:0009880 1 0.020
response to alkaloid GO:0043279 132 0.020
regulation of cell proliferation GO:0042127 359 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
regulation of secretion by cell GO:1903530 208 0.020
response to hypoxia GO:0001666 231 0.020
developmental process involved in reproduction GO:0003006 159 0.020
response to estrogen GO:0043627 232 0.020
positive regulation of transport GO:0051050 245 0.020
response to hexose GO:0009746 144 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
hormone transport GO:0009914 121 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
cation transmembrane transport GO:0098655 263 0.020
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.020
negative regulation of cell development GO:0010721 82 0.020
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.019
regulation of cell cycle GO:0051726 73 0.019
transmission of nerve impulse GO:0019226 42 0.019
protein oligomerization GO:0051259 191 0.019
purine nucleotide biosynthetic process GO:0006164 83 0.019
response to corticosteroid GO:0031960 235 0.019
ribose phosphate biosynthetic process GO:0046390 87 0.019
gastrulation GO:0007369 2 0.019
regulation of phosphorylation GO:0042325 248 0.019
inflammatory response GO:0006954 150 0.019
axis specification GO:0009798 4 0.018
single organism carbohydrate metabolic process GO:0044723 118 0.018
response to monosaccharide GO:0034284 159 0.018
carbohydrate derivative biosynthetic process GO:1901137 124 0.018
response to glucose GO:0009749 136 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
divalent inorganic cation transport GO:0072511 134 0.018
regulation of nervous system development GO:0051960 264 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
regulation of transferase activity GO:0051338 123 0.018
4 chlorobiphenyl metabolic process GO:0018880 1 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
cellular lipid metabolic process GO:0044255 208 0.018
single organism reproductive process GO:0044702 297 0.018
cellular ketone metabolic process GO:0042180 51 0.018
multicellular organismal signaling GO:0035637 44 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
cardiac chamber development GO:0003205 1 0.018
regulation of hormone secretion GO:0046883 106 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
negative regulation of gene expression GO:0010629 199 0.017
positive regulation of response to stimulus GO:0048584 285 0.017
negative regulation of cell communication GO:0010648 158 0.017
ovulation cycle GO:0042698 67 0.017
protein localization GO:0008104 191 0.017
positive regulation of gene expression GO:0010628 244 0.017
positive regulation of protein modification process GO:0031401 142 0.017
purine containing compound metabolic process GO:0072521 253 0.017
cell type specific apoptotic process GO:0097285 134 0.017
nucleotide biosynthetic process GO:0009165 98 0.017
response to molecule of bacterial origin GO:0002237 194 0.017
cellular response to alcohol GO:0097306 87 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
purine containing compound biosynthetic process GO:0072522 85 0.017
organic acid transport GO:0015849 116 0.016
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.016
aging GO:0007568 241 0.016
anion transmembrane transport GO:0098656 77 0.016
cellular catabolic process GO:0044248 295 0.016
positive regulation of cellular component movement GO:0051272 102 0.016
multicellular organism reproduction GO:0032504 233 0.016
calcium ion transport GO:0006816 131 0.016
cellular response to glucocorticoid stimulus GO:0071385 68 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
chromosome segregation GO:0007059 2 0.016
response to ketone GO:1901654 182 0.016
cytoplasmic transport GO:0016482 115 0.016
secretion by cell GO:0032940 248 0.016
response to ammonium ion GO:0060359 71 0.016
organelle organization GO:0006996 266 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
protein complex assembly GO:0006461 263 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
macromolecule localization GO:0033036 252 0.015
wound healing GO:0042060 122 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
nitrogen compound transport GO:0071705 229 0.015
response to carbohydrate GO:0009743 183 0.015
response to organophosphorus GO:0046683 102 0.015
mesoderm development GO:0007498 2 0.015
response to lipopolysaccharide GO:0032496 191 0.015
response to decreased oxygen levels GO:0036293 237 0.015
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.014
intracellular transport GO:0046907 185 0.014
female gonad development GO:0008585 53 0.014
carbohydrate metabolic process GO:0005975 130 0.014
negative regulation of neurogenesis GO:0050768 78 0.014
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
camp metabolic process GO:0046058 63 0.014
skeletal muscle tissue development GO:0007519 31 0.014
rna metabolic process GO:0016070 406 0.014
divalent metal ion transport GO:0070838 132 0.014
single organism catabolic process GO:0044712 283 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
bmp signaling pathway GO:0030509 4 0.014
positive regulation of cell death GO:0010942 184 0.014
cellular response to peptide GO:1901653 133 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
cellular component movement GO:0006928 248 0.014
regulation of neuron projection development GO:0010975 161 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.014
organic anion transport GO:0015711 132 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
reactive oxygen species metabolic process GO:0072593 37 0.014
regulation of transmembrane transport GO:0034762 122 0.014
striated muscle tissue development GO:0014706 58 0.013
circulatory system development GO:0072359 134 0.013
reproductive system development GO:0061458 128 0.013
regulation of system process GO:0044057 208 0.013
positive regulation of developmental process GO:0051094 283 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
regulation of synaptic transmission GO:0050804 141 0.013
sensory organ development GO:0007423 74 0.013
reproductive structure development GO:0048608 128 0.013
cyclic nucleotide biosynthetic process GO:0009190 63 0.013
cell activation GO:0001775 97 0.013
camp biosynthetic process GO:0006171 47 0.013
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.013
cellular response to peptide hormone stimulus GO:0071375 120 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
negative regulation of phosphorus metabolic process GO:0010563 80 0.013
growth GO:0040007 165 0.013
protein transport GO:0015031 132 0.013
regulation of nucleotide biosynthetic process GO:0030808 47 0.012
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
formation of primary germ layer GO:0001704 1 0.012
purine nucleoside monophosphate metabolic process GO:0009126 84 0.012
response to external biotic stimulus GO:0043207 221 0.012
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.012
estrogen catabolic process GO:0006711 1 0.012
regulation of blood pressure GO:0008217 83 0.012
mitotic cell cycle GO:0000278 49 0.012
jak stat cascade GO:0007259 26 0.012
positive regulation of multicellular organismal process GO:0051240 387 0.012
cyclic purine nucleotide metabolic process GO:0052652 62 0.012
behavior GO:0007610 205 0.012
negative regulation of molecular function GO:0044092 133 0.012
hormone metabolic process GO:0042445 69 0.012
regulation of cell projection organization GO:0031344 175 0.012
gliogenesis GO:0042063 93 0.012
regulation of interleukin 1 beta secretion GO:0050706 3 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
sexual reproduction GO:0019953 148 0.012
response to metal ion GO:0010038 253 0.012
regulation of response to external stimulus GO:0032101 106 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
regulation of mapk cascade GO:0043408 116 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
establishment of protein localization GO:0045184 141 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
regulation of camp metabolic process GO:0030814 43 0.011
response to progesterone GO:0032570 48 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
response to reactive oxygen species GO:0000302 120 0.011
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
localization of cell GO:0051674 202 0.011
catabolic process GO:0009056 351 0.011
lipid storage GO:0019915 1 0.011
gamete generation GO:0007276 124 0.011
muscle cell proliferation GO:0033002 84 0.011
female pregnancy GO:0007565 122 0.011
tube development GO:0035295 89 0.011
regulation of response to wounding GO:1903034 69 0.011
positive regulation of kinase activity GO:0033674 77 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
positive regulation of secretion GO:0051047 140 0.011
locomotion GO:0040011 237 0.011
circadian rhythm GO:0007623 88 0.011
response to hydrogen peroxide GO:0042542 89 0.011
cellular macromolecule localization GO:0070727 122 0.011
skeletal system development GO:0001501 41 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
male gamete generation GO:0048232 99 0.011
cardiovascular system development GO:0072358 134 0.011
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
regulation of cellular component organization GO:0051128 368 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
regulation of anatomical structure size GO:0090066 135 0.011
positive regulation of protein kinase activity GO:0045860 73 0.011
chemosensory behavior GO:0007635 2 0.011
response to axon injury GO:0048678 59 0.011
camera type eye development GO:0043010 48 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
cell migration GO:0016477 197 0.011
embryonic axis specification GO:0000578 1 0.011
meiotic cell cycle process GO:1903046 3 0.011
heterocycle catabolic process GO:0046700 167 0.010
organic substance catabolic process GO:1901575 316 0.010
cytosolic calcium ion transport GO:0060401 39 0.010
blood circulation GO:0008015 183 0.010
organ regeneration GO:0031100 101 0.010
neuron apoptotic process GO:0051402 88 0.010
response to radiation GO:0009314 137 0.010
cellular response to external stimulus GO:0071496 118 0.010
forebrain development GO:0030900 98 0.010
response to biotic stimulus GO:0009607 226 0.010
cell growth GO:0016049 104 0.010
peptide transport GO:0015833 97 0.010
cellular hormone metabolic process GO:0034754 49 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
neuron neuron synaptic transmission GO:0007270 60 0.010
proteolysis GO:0006508 175 0.010
rna localization GO:0006403 4 0.010

Hspg2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011