Rattus norvegicus

72 known processes

Nbn

nibrin

(Aliases: MGC93174,Nbs1)

Nbn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component biogenesis GO:0044085 368 0.121
rna metabolic process GO:0016070 406 0.111
regulation of rna metabolic process GO:0051252 391 0.111
macromolecular complex subunit organization GO:0043933 339 0.099
organic acid metabolic process GO:0006082 292 0.092
regulation of nucleic acid templated transcription GO:1903506 380 0.088
cellular component assembly GO:0022607 360 0.084
transcription dna templated GO:0006351 377 0.077
nucleotide metabolic process GO:0009117 279 0.075
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.066
regulation of multicellular organismal development GO:2000026 376 0.063
lipid metabolic process GO:0006629 283 0.061
regulation of transcription dna templated GO:0006355 374 0.060
nucleic acid templated transcription GO:0097659 379 0.056
regulation of rna biosynthetic process GO:2001141 381 0.054
regulation of cell differentiation GO:0045595 320 0.054
neuron differentiation GO:0030182 368 0.054
single organism catabolic process GO:0044712 283 0.053
organophosphate metabolic process GO:0019637 370 0.053
rna biosynthetic process GO:0032774 380 0.052
response to inorganic substance GO:0010035 377 0.045
positive regulation of developmental process GO:0051094 283 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.040
single organism intracellular transport GO:1902582 166 0.040
cellular response to oxygen containing compound GO:1901701 386 0.039
intracellular transport GO:0046907 185 0.038
regulation of molecular function GO:0065009 398 0.036
oxoacid metabolic process GO:0043436 290 0.035
catabolic process GO:0009056 351 0.035
protein complex assembly GO:0006461 263 0.034
negative regulation of multicellular organismal process GO:0051241 203 0.034
carboxylic acid metabolic process GO:0019752 289 0.034
actin filament based process GO:0030029 86 0.034
programmed cell death GO:0012501 392 0.034
apoptotic process GO:0006915 381 0.033
secretion GO:0046903 307 0.033
positive regulation of transcription dna templated GO:0045893 197 0.032
macromolecule localization GO:0033036 252 0.032
homeostatic process GO:0042592 331 0.032
hexose metabolic process GO:0019318 58 0.031
positive regulation of molecular function GO:0044093 230 0.031
positive regulation of multicellular organismal process GO:0051240 387 0.031
positive regulation of biosynthetic process GO:0009891 319 0.031
positive regulation of rna metabolic process GO:0051254 203 0.031
regulation of apoptotic process GO:0042981 335 0.029
behavior GO:0007610 205 0.029
positive regulation of nucleic acid templated transcription GO:1903508 197 0.029
single organism behavior GO:0044708 130 0.029
organelle organization GO:0006996 266 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.029
positive regulation of cellular biosynthetic process GO:0031328 295 0.028
positive regulation of rna biosynthetic process GO:1902680 197 0.027
nitrogen compound transport GO:0071705 229 0.027
regulation of programmed cell death GO:0043067 341 0.027
cellular catabolic process GO:0044248 295 0.026
purine containing compound metabolic process GO:0072521 253 0.026
negative regulation of response to stimulus GO:0048585 155 0.026
regulation of secretion by cell GO:1903530 208 0.025
cognition GO:0050890 92 0.025
nucleoside phosphate metabolic process GO:0006753 283 0.025
organic substance catabolic process GO:1901575 316 0.025
ribonucleoside metabolic process GO:0009119 174 0.025
carbohydrate metabolic process GO:0005975 130 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
reproductive process GO:0022414 372 0.025
regulation of cellular localization GO:0060341 263 0.023
positive regulation of cell differentiation GO:0045597 217 0.023
regulation of homeostatic process GO:0032844 101 0.023
macromolecular complex assembly GO:0065003 273 0.023
positive regulation of secretion by cell GO:1903532 128 0.023
chemical homeostasis GO:0048878 292 0.023
response to oxidative stress GO:0006979 186 0.023
glucose metabolic process GO:0006006 52 0.023
regulation of catalytic activity GO:0050790 304 0.023
ribose phosphate metabolic process GO:0019693 235 0.022
regulation of secretion GO:0051046 224 0.022
cellular amino acid metabolic process GO:0006520 107 0.022
protein complex subunit organization GO:0071822 302 0.021
neurological system process GO:0050877 219 0.021
reproduction GO:0000003 245 0.021
multicellular organism reproduction GO:0032504 233 0.021
developmental process involved in reproduction GO:0003006 159 0.021
cell type specific apoptotic process GO:0097285 134 0.021
regulation of cell development GO:0060284 263 0.021
protein oligomerization GO:0051259 191 0.021
response to hypoxia GO:0001666 231 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
proteolysis GO:0006508 175 0.020
regulation of b cell differentiation GO:0045577 1 0.020
cellular amine metabolic process GO:0044106 38 0.020
response to biotic stimulus GO:0009607 226 0.020
transcription from rna polymerase ii promoter GO:0006366 252 0.020
single organism biosynthetic process GO:0044711 342 0.020
single organism reproductive process GO:0044702 297 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.019
cellular response to stress GO:0033554 269 0.019
intracellular signal transduction GO:0035556 314 0.019
regulation of nervous system development GO:0051960 264 0.018
cellular response to endogenous stimulus GO:0071495 377 0.018
vesicle mediated transport GO:0016192 181 0.018
alternative mrna splicing via spliceosome GO:0000380 4 0.018
protein complex biogenesis GO:0070271 263 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
glycosyl compound catabolic process GO:1901658 126 0.018
neuron projection development GO:0031175 273 0.018
regulation of fat cell differentiation GO:0045598 3 0.018
regulation of neurogenesis GO:0050767 247 0.018
positive regulation of cell development GO:0010720 176 0.018
cellular homeostasis GO:0019725 252 0.017
response to external biotic stimulus GO:0043207 221 0.017
coenzyme metabolic process GO:0006732 86 0.017
purine nucleotide metabolic process GO:0006163 229 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
regulation of signal transduction GO:0009966 318 0.016
negative regulation of signaling GO:0023057 157 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
negative regulation of metabolic process GO:0009892 331 0.015
protein phosphorylation GO:0006468 345 0.015
single organism organelle organization GO:1902589 180 0.015
ion homeostasis GO:0050801 212 0.015
regulation of cellular component organization GO:0051128 368 0.015
amine metabolic process GO:0009308 38 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
cellular response to lipid GO:0071396 201 0.015
anatomical structure morphogenesis GO:0009653 298 0.015
cellular response to acid chemical GO:0071229 75 0.015
oxidation reduction process GO:0055114 304 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
positive regulation of cell death GO:0010942 184 0.014
cytoskeleton organization GO:0007010 111 0.014
negative regulation of developmental process GO:0051093 125 0.014
cell cell signaling GO:0007267 335 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
regulation of immunoglobulin production GO:0002637 4 0.014
establishment of protein localization GO:0045184 141 0.014
growth GO:0040007 165 0.014
rna localization GO:0006403 4 0.014
nucleoside metabolic process GO:0009116 179 0.013
blood circulation GO:0008015 183 0.013
cellular component movement GO:0006928 248 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
negative regulation of growth GO:0045926 37 0.013
negative regulation of cell communication GO:0010648 158 0.013
defense response GO:0006952 194 0.013
heterocycle catabolic process GO:0046700 167 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
response to wounding GO:0009611 254 0.013
cytoplasmic transport GO:0016482 115 0.013
regulation of neuron differentiation GO:0045664 208 0.013
regulation of endothelial cell apoptotic process GO:2000351 3 0.013
cofactor metabolic process GO:0051186 95 0.013
regulation of phosphorus metabolic process GO:0051174 349 0.012
regulation of phosphorylation GO:0042325 248 0.012
regulation of phosphate metabolic process GO:0019220 349 0.012
localization of cell GO:0051674 202 0.012
positive regulation of secretion GO:0051047 140 0.012
leukocyte activation GO:0045321 76 0.012
dna metabolic process GO:0006259 96 0.012
regulation of protein metabolic process GO:0051246 289 0.012
secretion by cell GO:0032940 248 0.012
developmental growth GO:0048589 100 0.012
spermatogenesis GO:0007283 99 0.012
ion transmembrane transport GO:0034220 365 0.012
regulation of neuron projection development GO:0010975 161 0.012
learning or memory GO:0007611 90 0.012
negative regulation of cell death GO:0060548 229 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
hormone transport GO:0009914 121 0.011
regulation of catabolic process GO:0009894 113 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
amide transport GO:0042886 105 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
positive regulation of gene expression GO:0010628 244 0.011
negative regulation of transport GO:0051051 136 0.011
circulatory system process GO:0003013 183 0.011
multi organism reproductive process GO:0044703 262 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
lipid localization GO:0010876 62 0.011
centrosome organization GO:0051297 1 0.011
gamete generation GO:0007276 124 0.011
regulation of hormone levels GO:0010817 187 0.011
carbohydrate derivative metabolic process GO:1901135 346 0.011
regulation of growth GO:0040008 105 0.010
regulation of peptide transport GO:0090087 87 0.010
cation homeostasis GO:0055080 195 0.010
response to molecule of bacterial origin GO:0002237 194 0.010
cellular cation homeostasis GO:0030003 180 0.010
cellular macromolecular complex assembly GO:0034622 58 0.010
memory GO:0007613 54 0.010
positive regulation of phosphorylation GO:0042327 177 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.010
cellular ketone metabolic process GO:0042180 51 0.010
axis specification GO:0009798 4 0.010
glycerolipid metabolic process GO:0046486 67 0.010
signal release GO:0023061 145 0.010
hormone secretion GO:0046879 115 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010
small gtpase mediated signal transduction GO:0007264 36 0.010

Nbn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
disease of metabolism DOID:0014667 0 0.012