Rattus norvegicus

26 known processes

Nampt

nicotinamide phosphoribosyltransferase

(Aliases: Pbef1,Pbef)

Nampt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of programmed cell death GO:0043067 341 0.253
programmed cell death GO:0012501 392 0.203
response to nutrient GO:0007584 248 0.152
cell migration GO:0016477 197 0.119
response to hypoxia GO:0001666 231 0.104
response to extracellular stimulus GO:0009991 380 0.103
regulation of apoptotic process GO:0042981 335 0.098
negative regulation of apoptotic process GO:0043066 181 0.095
positive regulation of cellular component movement GO:0051272 102 0.091
aging GO:0007568 241 0.088
response to nutrient levels GO:0031667 370 0.086
cellular component movement GO:0006928 248 0.080
protein complex subunit organization GO:0071822 302 0.077
negative regulation of programmed cell death GO:0043069 183 0.073
cellular response to hormone stimulus GO:0032870 247 0.073
apoptotic process GO:0006915 381 0.072
cell motility GO:0048870 202 0.069
regulation of cellular component movement GO:0051270 150 0.067
muscle cell proliferation GO:0033002 84 0.062
transcription dna templated GO:0006351 377 0.061
negative regulation of cell death GO:0060548 229 0.054
localization of cell GO:0051674 202 0.050
response to vitamin GO:0033273 131 0.049
regulation of cell motility GO:2000145 131 0.048
response to decreased oxygen levels GO:0036293 237 0.047
regulation of cellular component organization GO:0051128 368 0.047
response to inorganic substance GO:0010035 377 0.047
response to estrogen GO:0043627 232 0.045
macromolecular complex assembly GO:0065003 273 0.045
cellular response to stress GO:0033554 269 0.044
cellular component biogenesis GO:0044085 368 0.042
protein phosphorylation GO:0006468 345 0.041
positive regulation of cellular component organization GO:0051130 200 0.041
regulation of cellular ketone metabolic process GO:0010565 27 0.041
cell growth GO:0016049 104 0.039
regulation of cell differentiation GO:0045595 320 0.038
regulation of cell migration GO:0030334 128 0.038
response to isolation stress GO:0035900 2 0.037
response to molecule of bacterial origin GO:0002237 194 0.037
response to bacterium GO:0009617 200 0.037
response to reactive oxygen species GO:0000302 120 0.037
protein complex assembly GO:0006461 263 0.037
regulation of cellular amino acid metabolic process GO:0006521 2 0.036
regulation of locomotion GO:0040012 148 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.035
negative regulation of cell communication GO:0010648 158 0.035
regulation of cell projection organization GO:0031344 175 0.035
protein complex biogenesis GO:0070271 263 0.033
positive regulation of cellular amine metabolic process GO:0033240 3 0.033
rna metabolic process GO:0016070 406 0.033
positive regulation of biosynthetic process GO:0009891 319 0.032
response to hydrogen peroxide GO:0042542 89 0.031
cellular amino acid metabolic process GO:0006520 107 0.031
positive regulation of programmed cell death GO:0043068 157 0.031
cellular component assembly GO:0022607 360 0.031
cellular amine metabolic process GO:0044106 38 0.030
organophosphate metabolic process GO:0019637 370 0.030
anatomical structure morphogenesis GO:0009653 298 0.030
regulation of rna biosynthetic process GO:2001141 381 0.029
protein heterooligomerization GO:0051291 89 0.029
positive regulation of transcription dna templated GO:0045893 197 0.029
response to peptide GO:1901652 292 0.029
organelle organization GO:0006996 266 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.028
regulation of smooth muscle cell migration GO:0014910 36 0.028
carboxylic acid metabolic process GO:0019752 289 0.028
cellular response to endogenous stimulus GO:0071495 377 0.028
cellular ketone metabolic process GO:0042180 51 0.028
monocarboxylic acid metabolic process GO:0032787 152 0.027
cellular component morphogenesis GO:0032989 155 0.027
response to acid chemical GO:0001101 222 0.027
response to biotic stimulus GO:0009607 226 0.027
response to oxidative stress GO:0006979 186 0.026
positive regulation of cell projection organization GO:0031346 111 0.026
locomotion GO:0040011 237 0.026
growth GO:0040007 165 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.025
regulation of phosphorus metabolic process GO:0051174 349 0.025
positive regulation of cell migration GO:0030335 96 0.025
protein oligomerization GO:0051259 191 0.025
positive regulation of gene expression GO:0010628 244 0.024
regulation of nucleic acid templated transcription GO:1903506 380 0.024
oxoacid metabolic process GO:0043436 290 0.024
positive regulation of smooth muscle cell migration GO:0014911 27 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
smooth muscle cell migration GO:0014909 36 0.023
rna biosynthetic process GO:0032774 380 0.023
regulation of proteasomal protein catabolic process GO:0061136 4 0.023
response to cold GO:0009409 29 0.023
response to temperature stimulus GO:0009266 94 0.023
regulation of smooth muscle cell proliferation GO:0048660 75 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
cellular response to alcohol GO:0097306 87 0.022
positive regulation of cell development GO:0010720 176 0.022
female pregnancy GO:0007565 122 0.022
positive regulation of neuron projection development GO:0010976 99 0.022
cardiovascular system development GO:0072358 134 0.022
response to other organism GO:0051707 220 0.022
cellular response to cytokine stimulus GO:0071345 127 0.021
negative regulation of metabolic process GO:0009892 331 0.021
kidney development GO:0001822 67 0.021
response to cytokine GO:0034097 215 0.021
cellular response to oxygen containing compound GO:1901701 386 0.021
positive regulation of nervous system development GO:0051962 178 0.021
response to ethanol GO:0045471 162 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
bmp signaling pathway GO:0030509 4 0.021
catabolic process GO:0009056 351 0.021
mapk cascade GO:0000165 140 0.020
regulation of neurogenesis GO:0050767 247 0.020
gastrulation GO:0007369 2 0.020
muscle cell migration GO:0014812 36 0.020
negative regulation of molecular function GO:0044092 133 0.020
cell projection organization GO:0030030 302 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
cell morphogenesis GO:0000902 142 0.020
regulation of nervous system development GO:0051960 264 0.020
positive regulation of cell death GO:0010942 184 0.020
regulation of cell development GO:0060284 263 0.020
tissue remodeling GO:0048771 40 0.020
transcription from rna polymerase ii promoter GO:0006366 252 0.019
vasculature development GO:0001944 70 0.019
reactive oxygen species biosynthetic process GO:1903409 8 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.019
cellular response to reactive oxygen species GO:0034614 55 0.019
organic substance catabolic process GO:1901575 316 0.019
positive regulation of neuron differentiation GO:0045666 126 0.019
single organism carbohydrate metabolic process GO:0044723 118 0.019
regulation of metanephros development GO:0072215 4 0.019
cellular response to oxidative stress GO:0034599 76 0.018
amine metabolic process GO:0009308 38 0.018
regulation of multicellular organismal development GO:2000026 376 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
regulation of protein metabolic process GO:0051246 289 0.018
regulation of cell proliferation GO:0042127 359 0.018
regulation of anatomical structure morphogenesis GO:0022603 141 0.018
organic acid metabolic process GO:0006082 292 0.018
response to growth factor GO:0070848 189 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
transmembrane transport GO:0055085 412 0.018
positive regulation of cell differentiation GO:0045597 217 0.017
nucleotide metabolic process GO:0009117 279 0.017
brain development GO:0007420 247 0.017
regulation of neuron projection development GO:0010975 161 0.017
response to carbohydrate GO:0009743 183 0.017
response to glucose GO:0009749 136 0.017
regulation of rna metabolic process GO:0051252 391 0.017
response to external biotic stimulus GO:0043207 221 0.017
positive regulation of multicellular organismal process GO:0051240 387 0.016
response to oxygen levels GO:0070482 265 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
nucleic acid templated transcription GO:0097659 379 0.016
secretion GO:0046903 307 0.016
response to wounding GO:0009611 254 0.016
neuron death GO:0070997 127 0.016
negative regulation of cellular metabolic process GO:0031324 281 0.016
regulation of neuron differentiation GO:0045664 208 0.016
neuron projection development GO:0031175 273 0.016
stress activated protein kinase signaling cascade GO:0031098 37 0.016
cellular carbohydrate metabolic process GO:0044262 72 0.016
negative regulation of signaling GO:0023057 157 0.016
organ regeneration GO:0031100 101 0.016
regulation of cell growth GO:0001558 85 0.016
chromosome segregation GO:0007059 2 0.016
response to estradiol GO:0032355 164 0.015
proteolysis GO:0006508 175 0.015
regulation of transcription dna templated GO:0006355 374 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
central nervous system development GO:0007417 311 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
reactive oxygen species metabolic process GO:0072593 37 0.015
regulation of neuron death GO:1901214 115 0.015
regulation of signal transduction GO:0009966 318 0.015
cellular response to insulin stimulus GO:0032869 81 0.015
regulation of phosphate metabolic process GO:0019220 349 0.015
protein homooligomerization GO:0051260 91 0.015
renal system development GO:0072001 67 0.014
intracellular transport GO:0046907 185 0.014
single organism biosynthetic process GO:0044711 342 0.014
protein autophosphorylation GO:0046777 66 0.014
regulation of catalytic activity GO:0050790 304 0.014
protein transport GO:0015031 132 0.014
positive regulation of cell motility GO:2000147 97 0.014
muscle contraction GO:0006936 88 0.014
smooth muscle cell proliferation GO:0048659 77 0.014
response to toxic substance GO:0009636 133 0.013
monosaccharide metabolic process GO:0005996 61 0.013
positive regulation of developmental process GO:0051094 283 0.013
response to electrical stimulus GO:0051602 56 0.013
response to insulin GO:0032868 133 0.013
intracellular signal transduction GO:0035556 314 0.013
circulatory system development GO:0072359 134 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
response to hexose GO:0009746 144 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
carbohydrate metabolic process GO:0005975 130 0.013
response to metal ion GO:0010038 253 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
positive regulation of locomotion GO:0040017 102 0.013
gland development GO:0048732 155 0.013
positive regulation of transport GO:0051050 245 0.012
positive regulation of endothelial cell migration GO:0010595 4 0.012
single organism reproductive process GO:0044702 297 0.012
regeneration GO:0031099 163 0.012
response to corticosteroid GO:0031960 235 0.012
response to radiation GO:0009314 137 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
regulation of phosphorylation GO:0042325 248 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.012
peptidyl amino acid modification GO:0018193 126 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
negative regulation of gene expression GO:0010629 199 0.012
regulation of reactive oxygen species metabolic process GO:2000377 26 0.012
positive regulation of molecular function GO:0044093 230 0.012
single organism organelle organization GO:1902589 180 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
cyclic nucleotide metabolic process GO:0009187 80 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
gonad development GO:0008406 104 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
cellular catabolic process GO:0044248 295 0.012
regulation of secretion GO:0051046 224 0.012
response to glucocorticoid GO:0051384 223 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
lipid metabolic process GO:0006629 283 0.012
synaptic transmission GO:0007268 235 0.012
positive regulation of secretion GO:0051047 140 0.012
neuron projection morphogenesis GO:0048812 122 0.012
regulation of necroptotic process GO:0060544 2 0.011
neuron differentiation GO:0030182 368 0.011
ion transmembrane transport GO:0034220 365 0.011
sex differentiation GO:0007548 113 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
positive regulation of signaling GO:0023056 270 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
response to monosaccharide GO:0034284 159 0.011
homeostatic process GO:0042592 331 0.011
negative regulation of signal transduction GO:0009968 83 0.011
chemical homeostasis GO:0048878 292 0.011
muscle system process GO:0003012 115 0.011
positive regulation of cell communication GO:0010647 271 0.011
urogenital system development GO:0001655 78 0.011
ion homeostasis GO:0050801 212 0.011
salivary gland morphogenesis GO:0007435 1 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
multicellular organism growth GO:0035264 1 0.011
dna metabolic process GO:0006259 96 0.011
cell projection morphogenesis GO:0048858 123 0.011
metal ion transport GO:0030001 289 0.011
circulatory system process GO:0003013 183 0.011
regulation of cell adhesion GO:0030155 52 0.011
head development GO:0060322 247 0.011
programmed necrotic cell death GO:0097300 2 0.011
fatty acid metabolic process GO:0006631 99 0.011
behavior GO:0007610 205 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
response to lipopolysaccharide GO:0032496 191 0.011
gliogenesis GO:0042063 93 0.010
positive regulation of protein metabolic process GO:0051247 178 0.010
lipid storage GO:0019915 1 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
blood vessel morphogenesis GO:0048514 58 0.010
response to manganese ion GO:0010042 13 0.010

Nampt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.022
amino acid metabolic disorder DOID:9252 0 0.015
inherited metabolic disorder DOID:655 0 0.015
organic acidemia DOID:0060159 0 0.015
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011