Rattus norvegicus

0 known processes

Usp8

ubiquitin specific peptidase 8

Usp8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component biogenesis GO:0044085 368 0.121
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.091
macromolecular complex subunit organization GO:0043933 339 0.074
Yeast
single organism catabolic process GO:0044712 283 0.061
response to extracellular stimulus GO:0009991 380 0.061
organic acid metabolic process GO:0006082 292 0.060
reproduction GO:0000003 245 0.060
organelle organization GO:0006996 266 0.053
Yeast
reproductive process GO:0022414 372 0.052
ribose phosphate metabolic process GO:0019693 235 0.052
macromolecular complex assembly GO:0065003 273 0.049
head development GO:0060322 247 0.049
transcription dna templated GO:0006351 377 0.047
regulation of cellular component organization GO:0051128 368 0.047
cellular component assembly GO:0022607 360 0.044
negative regulation of cellular metabolic process GO:0031324 281 0.042
multicellular organism reproduction GO:0032504 233 0.042
response to estrogen GO:0043627 232 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.041
multicellular organismal reproductive process GO:0048609 233 0.041
cellular response to endogenous stimulus GO:0071495 377 0.041
organophosphate metabolic process GO:0019637 370 0.041
negative regulation of metabolic process GO:0009892 331 0.040
protein complex biogenesis GO:0070271 263 0.040
protein complex assembly GO:0006461 263 0.040
ion transmembrane transport GO:0034220 365 0.040
regulation of catalytic activity GO:0050790 304 0.040
oxoacid metabolic process GO:0043436 290 0.039
response to nutrient levels GO:0031667 370 0.038
apoptotic process GO:0006915 381 0.038
rna metabolic process GO:0016070 406 0.037
regulation of rna metabolic process GO:0051252 391 0.037
nucleobase containing small molecule metabolic process GO:0055086 316 0.037
central nervous system development GO:0007417 311 0.037
response to ethanol GO:0045471 162 0.035
transmembrane transport GO:0055085 412 0.035
nucleotide metabolic process GO:0009117 279 0.035
purine ribonucleotide metabolic process GO:0009150 227 0.034
regulation of protein metabolic process GO:0051246 289 0.034
positive regulation of molecular function GO:0044093 230 0.034
regulation of transcription dna templated GO:0006355 374 0.034
tissue development GO:0009888 252 0.034
Rat
nucleic acid templated transcription GO:0097659 379 0.033
neuron development GO:0048666 286 0.033
protein complex subunit organization GO:0071822 302 0.033
Yeast
vesicle mediated transport GO:0016192 181 0.033
Yeast
brain development GO:0007420 247 0.032
cellular response to oxygen containing compound GO:1901701 386 0.032
catabolic process GO:0009056 351 0.032
Yeast
regulation of cell development GO:0060284 263 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.031
nucleoside phosphate metabolic process GO:0006753 283 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.030
ribonucleotide metabolic process GO:0009259 231 0.030
anion transport GO:0006820 178 0.030
regulation of multicellular organismal development GO:2000026 376 0.029
Rat
organic substance catabolic process GO:1901575 316 0.028
Yeast
regulation of phosphate metabolic process GO:0019220 349 0.028
lipid biosynthetic process GO:0008610 128 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.027
carboxylic acid metabolic process GO:0019752 289 0.027
single organism reproductive process GO:0044702 297 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.027
positive regulation of nucleic acid templated transcription GO:1903508 197 0.027
response to toxic substance GO:0009636 133 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
multi organism reproductive process GO:0044703 262 0.027
regulation of nucleic acid templated transcription GO:1903506 380 0.026
cation transmembrane transport GO:0098655 263 0.026
neuron death GO:0070997 127 0.026
regulation of phosphorus metabolic process GO:0051174 349 0.026
single organism biosynthetic process GO:0044711 342 0.026
positive regulation of rna metabolic process GO:0051254 203 0.025
neuron differentiation GO:0030182 368 0.025
regulation of molecular function GO:0065009 398 0.025
sexual reproduction GO:0019953 148 0.025
intracellular signal transduction GO:0035556 314 0.025
transcription from rna polymerase ii promoter GO:0006366 252 0.025
anatomical structure morphogenesis GO:0009653 298 0.025
Fly
cellular response to nitrogen compound GO:1901699 210 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
response to peptide hormone GO:0043434 278 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
homeostatic process GO:0042592 331 0.024
Yeast
regulation of cell differentiation GO:0045595 320 0.024
cellular amino acid metabolic process GO:0006520 107 0.024
nitrogen compound transport GO:0071705 229 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
cellular ketone metabolic process GO:0042180 51 0.024
neurological system process GO:0050877 219 0.024
response to estradiol GO:0032355 164 0.023
purine containing compound metabolic process GO:0072521 253 0.023
gamete generation GO:0007276 124 0.023
negative regulation of cellular biosynthetic process GO:0031327 161 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
nucleoside metabolic process GO:0009116 179 0.023
positive regulation of transcription dna templated GO:0045893 197 0.022
glycosyl compound metabolic process GO:1901657 182 0.022
response to radiation GO:0009314 137 0.022
negative regulation of gene expression GO:0010629 199 0.022
secretion GO:0046903 307 0.022
positive regulation of developmental process GO:0051094 283 0.022
Rat
cation transport GO:0006812 382 0.022
positive regulation of gene expression GO:0010628 244 0.022
cellular response to organic cyclic compound GO:0071407 202 0.022
single organism organelle organization GO:1902589 180 0.022
Yeast
regulation of vesicle mediated transport GO:0060627 81 0.022
negative regulation of multicellular organismal process GO:0051241 203 0.021
Rat
regulation of anatomical structure size GO:0090066 135 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
cellular response to stress GO:0033554 269 0.021
positive regulation of transport GO:0051050 245 0.021
developmental growth GO:0048589 100 0.021
metal ion transport GO:0030001 289 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
behavior GO:0007610 205 0.021
organonitrogen compound catabolic process GO:1901565 179 0.021
response to peptide GO:1901652 292 0.021
regulation of nervous system development GO:0051960 264 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.021
cell projection organization GO:0030030 302 0.020
programmed cell death GO:0012501 392 0.020
positive regulation of rna biosynthetic process GO:1902680 197 0.020
ribonucleoside metabolic process GO:0009119 174 0.020
nucleotide catabolic process GO:0009166 139 0.020
amine metabolic process GO:0009308 38 0.020
response to nutrient GO:0007584 248 0.020
purine nucleoside triphosphate metabolic process GO:0009144 141 0.020
rna biosynthetic process GO:0032774 380 0.020
negative regulation of apoptotic process GO:0043066 181 0.020
chemical homeostasis GO:0048878 292 0.020
cell morphogenesis GO:0000902 142 0.020
protein oligomerization GO:0051259 191 0.019
response to corticosteroid GO:0031960 235 0.019
synaptic transmission GO:0007268 235 0.019
cellular amine metabolic process GO:0044106 38 0.019
cell activation GO:0001775 97 0.019
regulation of cellular localization GO:0060341 263 0.019
nucleoside triphosphate metabolic process GO:0009141 144 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.018
rhythmic process GO:0048511 156 0.018
organic acid transport GO:0015849 116 0.018
purine nucleotide metabolic process GO:0006163 229 0.018
purine nucleoside metabolic process GO:0042278 169 0.018
response to external biotic stimulus GO:0043207 221 0.018
growth GO:0040007 165 0.018
cellular homeostasis GO:0019725 252 0.018
Yeast
macromolecule localization GO:0033036 252 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
organic hydroxy compound metabolic process GO:1901615 115 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
positive regulation of signaling GO:0023056 270 0.018
Fly
negative regulation of cell death GO:0060548 229 0.018
neuron projection development GO:0031175 273 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
cytoplasmic transport GO:0016482 115 0.017
regulation of neurogenesis GO:0050767 247 0.017
ribonucleoside catabolic process GO:0042454 126 0.017
regulation of neuron apoptotic process GO:0043523 83 0.017
nucleoside triphosphate catabolic process GO:0009143 123 0.017
protein phosphorylation GO:0006468 345 0.017
ribonucleoside monophosphate metabolic process GO:0009161 88 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
organic cyclic compound catabolic process GO:1901361 175 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
response to decreased oxygen levels GO:0036293 237 0.016
response to other organism GO:0051707 220 0.016
aromatic compound catabolic process GO:0019439 168 0.016
ribonucleotide catabolic process GO:0009261 136 0.016
regulation of apoptotic process GO:0042981 335 0.016
oxidation reduction process GO:0055114 304 0.016
response to ammonium ion GO:0060359 71 0.016
intracellular transport GO:0046907 185 0.016
Yeast
positive regulation of phosphorylation GO:0042327 177 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
negative regulation of protein metabolic process GO:0051248 114 0.016
circadian rhythm GO:0007623 88 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
cytoskeleton organization GO:0007010 111 0.016
cellular chemical homeostasis GO:0055082 247 0.015
positive regulation of multicellular organismal process GO:0051240 387 0.015
Rat
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
regulation of neuron differentiation GO:0045664 208 0.015
response to carbohydrate GO:0009743 183 0.015
response to acid chemical GO:0001101 222 0.015
lipid metabolic process GO:0006629 283 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
multicellular organism growth GO:0035264 1 0.014
regulation of programmed cell death GO:0043067 341 0.014
regulation of cell proliferation GO:0042127 359 0.014
anterior posterior pattern specification GO:0009952 1 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
neuronal action potential GO:0019228 35 0.014
response to hypoxia GO:0001666 231 0.014
positive regulation of protein modification process GO:0031401 142 0.014
regulation of hormone levels GO:0010817 187 0.014
response to inorganic substance GO:0010035 377 0.014
organic anion transport GO:0015711 132 0.014
spermatogenesis GO:0007283 99 0.014
negative regulation of cell development GO:0010721 82 0.014
regulation of system process GO:0044057 208 0.014
response to hexose GO:0009746 144 0.014
asymmetric protein localization GO:0008105 2 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
secretion by cell GO:0032940 248 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
positive regulation of response to stimulus GO:0048584 285 0.013
Fly
heterocycle catabolic process GO:0046700 167 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
small molecule biosynthetic process GO:0044283 124 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
regulation of secretion GO:0051046 224 0.013
transmission of nerve impulse GO:0019226 42 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
regulation of hydrolase activity GO:0051336 143 0.013
peptide transport GO:0015833 97 0.013
regulation of cell adhesion GO:0030155 52 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
regulation of membrane potential GO:0042391 110 0.013
response to oxygen levels GO:0070482 265 0.013
spindle organization GO:0007051 2 0.013
nucleoside monophosphate metabolic process GO:0009123 93 0.013
amide transport GO:0042886 105 0.013
positive regulation of nervous system development GO:0051962 178 0.012
cell adhesion GO:0007155 110 0.012
regulation of neuron death GO:1901214 115 0.012
cell type specific apoptotic process GO:0097285 134 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
purine nucleoside monophosphate metabolic process GO:0009126 84 0.012
response to growth factor GO:0070848 189 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
defense response GO:0006952 194 0.012
establishment of protein localization GO:0045184 141 0.012
male gamete generation GO:0048232 99 0.012
cellular catabolic process GO:0044248 295 0.012
Yeast
regulation of signal transduction GO:0009966 318 0.012
Fly
purine ribonucleotide catabolic process GO:0009154 136 0.012
regulation of growth GO:0040008 105 0.012
cell cell signaling GO:0007267 335 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
regulation of phosphorylation GO:0042325 248 0.012
carboxylic acid transport GO:0046942 115 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
purine containing compound catabolic process GO:0072523 138 0.012
cellular component morphogenesis GO:0032989 155 0.012
cellular response to peptide GO:1901653 133 0.012
negative regulation of molecular function GO:0044092 133 0.012
cellular lipid metabolic process GO:0044255 208 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
epithelium development GO:0060429 96 0.012
negative regulation of cell differentiation GO:0045596 99 0.011
multicellular organismal signaling GO:0035637 44 0.011
aging GO:0007568 241 0.011
hepaticobiliary system development GO:0061008 90 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
response to glucocorticoid GO:0051384 223 0.011
single organism behavior GO:0044708 130 0.011
response to glucose GO:0009749 136 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
negative regulation of neuron apoptotic process GO:0043524 45 0.011
negative regulation of developmental process GO:0051093 125 0.011
Rat
purine ribonucleoside catabolic process GO:0046130 124 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
response to fatty acid GO:0070542 65 0.011
response to alkaloid GO:0043279 132 0.011
neural crest cell differentiation GO:0014033 2 0.011
protein localization GO:0008104 191 0.011
gastrulation GO:0007369 2 0.011
cellular ion homeostasis GO:0006873 184 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
nucleoside monophosphate catabolic process GO:0009125 56 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
positive regulation of fatty acid beta oxidation GO:0032000 4 0.011
regulation of response to stress GO:0080134 126 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
embryonic pattern specification GO:0009880 1 0.010
positive regulation of protein phosphorylation GO:0001934 135 0.010
gland development GO:0048732 155 0.010
synaptic growth at neuromuscular junction GO:0051124 1 0.010
ras protein signal transduction GO:0007265 29 0.010
rna localization GO:0006403 4 0.010
cellular protein localization GO:0034613 122 0.010
organophosphate catabolic process GO:0046434 148 0.010
response to vitamin GO:0033273 131 0.010
cellular macromolecular complex assembly GO:0034622 58 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
regulation of protein phosphorylation GO:0001932 183 0.010
muscle system process GO:0003012 115 0.010
nucleoside catabolic process GO:0009164 126 0.010
lipid storage GO:0019915 1 0.010
cellular response to lipid GO:0071396 201 0.010
regulation of secretion by cell GO:1903530 208 0.010
positive regulation of cellular catabolic process GO:0031331 71 0.010
carboxylic acid biosynthetic process GO:0046394 83 0.010

Usp8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.017
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.010