Rattus norvegicus

67 known processes

Usp3

ubiquitin specific peptidase 3

Usp3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription dna templated GO:0006355 374 0.103
rna metabolic process GO:0016070 406 0.101
regulation of molecular function GO:0065009 398 0.086
negative regulation of cellular metabolic process GO:0031324 281 0.085
cellular amino acid metabolic process GO:0006520 107 0.078
regulation of rna biosynthetic process GO:2001141 381 0.076
regulation of phosphorus metabolic process GO:0051174 349 0.073
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.071
transcription dna templated GO:0006351 377 0.066
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.063
intracellular signal transduction GO:0035556 314 0.060
regulation of rna metabolic process GO:0051252 391 0.059
nucleic acid templated transcription GO:0097659 379 0.057
regulation of cell differentiation GO:0045595 320 0.053
regulation of protein metabolic process GO:0051246 289 0.053
transcription from rna polymerase ii promoter GO:0006366 252 0.053
regulation of catalytic activity GO:0050790 304 0.052
regulation of apoptotic process GO:0042981 335 0.050
macromolecular complex subunit organization GO:0043933 339 0.049
protein complex subunit organization GO:0071822 302 0.049
apoptotic process GO:0006915 381 0.048
protein phosphorylation GO:0006468 345 0.047
programmed cell death GO:0012501 392 0.046
carboxylic acid metabolic process GO:0019752 289 0.045
regulation of cell proliferation GO:0042127 359 0.043
negative regulation of metabolic process GO:0009892 331 0.041
single organism reproductive process GO:0044702 297 0.040
organelle organization GO:0006996 266 0.040
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.039
neuron development GO:0048666 286 0.038
cellular ketone metabolic process GO:0042180 51 0.038
cellular component biogenesis GO:0044085 368 0.038
regulation of programmed cell death GO:0043067 341 0.038
homeostatic process GO:0042592 331 0.038
negative regulation of cell proliferation GO:0008285 119 0.038
positive regulation of cell death GO:0010942 184 0.037
regulation of cellular ketone metabolic process GO:0010565 27 0.037
negative regulation of programmed cell death GO:0043069 183 0.037
regulation of nucleic acid templated transcription GO:1903506 380 0.037
regulation of cellular protein metabolic process GO:0032268 267 0.036
positive regulation of transcription dna templated GO:0045893 197 0.034
cellular component assembly GO:0022607 360 0.034
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.034
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.033
regulation of signal transduction GO:0009966 318 0.033
regulation of phosphate metabolic process GO:0019220 349 0.033
regulation of apoptotic signaling pathway GO:2001233 13 0.032
regulation of phosphorylation GO:0042325 248 0.032
regulation of cellular component organization GO:0051128 368 0.032
macromolecular complex assembly GO:0065003 273 0.032
regulation of protein phosphorylation GO:0001932 183 0.032
regulation of protein modification process GO:0031399 194 0.031
positive regulation of rna metabolic process GO:0051254 203 0.031
anterior posterior pattern specification GO:0009952 1 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
positive regulation of catalytic activity GO:0043085 184 0.030
response to inorganic substance GO:0010035 377 0.030
oxoacid metabolic process GO:0043436 290 0.030
positive regulation of response to stimulus GO:0048584 285 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.029
neuron differentiation GO:0030182 368 0.029
positive regulation of molecular function GO:0044093 230 0.028
central nervous system development GO:0007417 311 0.028
positive regulation of cellular biosynthetic process GO:0031328 295 0.028
positive regulation of rna biosynthetic process GO:1902680 197 0.028
organic acid metabolic process GO:0006082 292 0.027
amine metabolic process GO:0009308 38 0.027
catabolic process GO:0009056 351 0.027
negative regulation of biosynthetic process GO:0009890 168 0.027
protein complex assembly GO:0006461 263 0.027
protein complex biogenesis GO:0070271 263 0.027
intracellular transport GO:0046907 185 0.027
regulation of kinase activity GO:0043549 117 0.027
reproductive system development GO:0061458 128 0.027
protein oligomerization GO:0051259 191 0.026
peptidyl amino acid modification GO:0018193 126 0.026
negative regulation of cell communication GO:0010648 158 0.026
rna biosynthetic process GO:0032774 380 0.026
lipid metabolic process GO:0006629 283 0.026
positive regulation of phosphate metabolic process GO:0045937 262 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.025
positive regulation of cell communication GO:0010647 271 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
regulation of multicellular organismal development GO:2000026 376 0.025
cellular catabolic process GO:0044248 295 0.025
reproductive process GO:0022414 372 0.025
peptide biosynthetic process GO:0043043 3 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
regulation of intracellular signal transduction GO:1902531 218 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
positive regulation of programmed cell death GO:0043068 157 0.024
positive regulation of signal transduction GO:0009967 175 0.023
regulation of catabolic process GO:0009894 113 0.023
axis specification GO:0009798 4 0.023
apoptotic signaling pathway GO:0097190 27 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.023
positive regulation of cellular protein metabolic process GO:0032270 167 0.022
negative regulation of response to stimulus GO:0048585 155 0.022
response to oxidative stress GO:0006979 186 0.022
cellular amine metabolic process GO:0044106 38 0.022
negative regulation of signaling GO:0023057 157 0.022
cellular component morphogenesis GO:0032989 155 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
chemical homeostasis GO:0048878 292 0.022
gastrulation GO:0007369 2 0.022
negative regulation of multicellular organismal process GO:0051241 203 0.021
positive regulation of gene expression GO:0010628 244 0.021
positive regulation of signaling GO:0023056 270 0.021
aging GO:0007568 241 0.021
positive regulation of apoptotic process GO:0043065 154 0.021
regulation of cellular catabolic process GO:0031329 101 0.020
reproduction GO:0000003 245 0.020
neuron projection development GO:0031175 273 0.020
cell projection organization GO:0030030 302 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
purine containing compound metabolic process GO:0072521 253 0.020
negative regulation of signal transduction GO:0009968 83 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
response to wounding GO:0009611 254 0.019
single organism biosynthetic process GO:0044711 342 0.019
response to toxic substance GO:0009636 133 0.019
head development GO:0060322 247 0.019
protein heterooligomerization GO:0051291 89 0.019
developmental process involved in reproduction GO:0003006 159 0.019
macromolecule localization GO:0033036 252 0.019
cellular response to lipid GO:0071396 201 0.019
behavior GO:0007610 205 0.019
multi organism reproductive process GO:0044703 262 0.019
cellular response to stress GO:0033554 269 0.019
carbohydrate derivative metabolic process GO:1901135 346 0.019
response to nutrient levels GO:0031667 370 0.019
positive regulation of hydrolase activity GO:0051345 86 0.019
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 1 0.019
single organism behavior GO:0044708 130 0.018
regulation of membrane potential GO:0042391 110 0.018
cell type specific apoptotic process GO:0097285 134 0.018
regulation of hydrolase activity GO:0051336 143 0.018
response to cytokine GO:0034097 215 0.018
dna metabolic process GO:0006259 96 0.017
regulation of protein kinase activity GO:0045859 105 0.017
sexual reproduction GO:0019953 148 0.017
metal ion transport GO:0030001 289 0.017
cation transmembrane transport GO:0098655 263 0.017
ion transmembrane transport GO:0034220 365 0.017
single organism organelle organization GO:1902589 180 0.017
brain development GO:0007420 247 0.017
response to transition metal nanoparticle GO:1990267 122 0.017
regulation of cell development GO:0060284 263 0.017
organic substance catabolic process GO:1901575 316 0.017
proteolysis GO:0006508 175 0.016
erythrocyte differentiation GO:0030218 1 0.016
transmembrane transport GO:0055085 412 0.016
regulation of hormone levels GO:0010817 187 0.016
positive regulation of transport GO:0051050 245 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
gamete generation GO:0007276 124 0.016
secretion GO:0046903 307 0.016
cellular response to oxygen containing compound GO:1901701 386 0.016
single organism cellular localization GO:1902580 102 0.016
signal transduction in absence of ligand GO:0038034 5 0.015
response to reactive oxygen species GO:0000302 120 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
neurological system process GO:0050877 219 0.015
reproductive structure development GO:0048608 128 0.015
regulation of cellular response to stress GO:0080135 49 0.015
regulation of transferase activity GO:0051338 123 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
response to acid chemical GO:0001101 222 0.015
cellular component movement GO:0006928 248 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
response to extracellular stimulus GO:0009991 380 0.014
activation of cysteine type endopeptidase activity GO:0097202 4 0.014
ras protein signal transduction GO:0007265 29 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
multicellular organism growth GO:0035264 1 0.014
nucleotide metabolic process GO:0009117 279 0.014
sex differentiation GO:0007548 113 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
eye morphogenesis GO:0048592 4 0.014
erythrocyte homeostasis GO:0034101 2 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
regulation of response to stress GO:0080134 126 0.014
oxidation reduction process GO:0055114 304 0.014
positive regulation of mapk cascade GO:0043410 92 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.014
response to lipopolysaccharide GO:0032496 191 0.014
response to growth factor GO:0070848 189 0.014
gliogenesis GO:0042063 93 0.014
response to hydrogen peroxide GO:0042542 89 0.013
positive regulation of cell proliferation GO:0008284 249 0.013
tube development GO:0035295 89 0.013
immune system process GO:0002376 204 0.013
tissue development GO:0009888 252 0.013
cytoskeleton organization GO:0007010 111 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
male gamete generation GO:0048232 99 0.013
regulation of nervous system development GO:0051960 264 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
cation transport GO:0006812 382 0.013
spermatogenesis GO:0007283 99 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
multicellular organism reproduction GO:0032504 233 0.013
negative regulation of cell death GO:0060548 229 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
regulation of response to external stimulus GO:0032101 106 0.013
response to metal ion GO:0010038 253 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.012
secretion by cell GO:0032940 248 0.012
response to bacterium GO:0009617 200 0.012
response to external biotic stimulus GO:0043207 221 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
cytoplasmic transport GO:0016482 115 0.012
anatomical structure morphogenesis GO:0009653 298 0.012
organophosphate metabolic process GO:0019637 370 0.012
regulation of neurogenesis GO:0050767 247 0.012
regulation of ion transport GO:0043269 245 0.012
embryonic axis specification GO:0000578 1 0.012
negative regulation of molecular function GO:0044092 133 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
amide biosynthetic process GO:0043604 10 0.012
nucleotide catabolic process GO:0009166 139 0.012
learning or memory GO:0007611 90 0.012
negative regulation of transport GO:0051051 136 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
regulation of dna metabolic process GO:0051052 60 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.011
development of primary sexual characteristics GO:0045137 107 0.011
response to ethanol GO:0045471 162 0.011
protein localization GO:0008104 191 0.011
response to alkaloid GO:0043279 132 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
rhythmic process GO:0048511 156 0.011
heart morphogenesis GO:0003007 3 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.011
cell morphogenesis GO:0000902 142 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
vesicle mediated transport GO:0016192 181 0.011
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 4 0.011
localization of cell GO:0051674 202 0.011
hematopoietic progenitor cell differentiation GO:0002244 2 0.011
response to corticosteroid GO:0031960 235 0.011
response to oxygen levels GO:0070482 265 0.010
response to decreased oxygen levels GO:0036293 237 0.010
rna localization GO:0006403 4 0.010
negative regulation of apoptotic process GO:0043066 181 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 3 0.010
microtubule organizing center organization GO:0031023 1 0.010
cellular response to external stimulus GO:0071496 118 0.010
forebrain development GO:0030900 98 0.010
regulation of lipid metabolic process GO:0019216 68 0.010
single organism catabolic process GO:0044712 283 0.010
regulation of cellular localization GO:0060341 263 0.010
adult locomotory behavior GO:0008344 4 0.010
regulation of secretion GO:0051046 224 0.010
response to ketone GO:1901654 182 0.010
negative regulation of phosphorus metabolic process GO:0010563 80 0.010
cellular response to endogenous stimulus GO:0071495 377 0.010
negative regulation of neurogenesis GO:0050768 78 0.010

Usp3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
organ system cancer DOID:0050686 0 0.020