Rattus norvegicus

0 known processes

Usp4

ubiquitin specific peptidase 4 (proto-oncogene)

Usp4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
organic substance catabolic process GO:1901575 316 0.098
macromolecular complex subunit organization GO:0043933 339 0.067
programmed cell death GO:0012501 392 0.061
regulation of cell proliferation GO:0042127 359 0.057
single organism organelle organization GO:1902589 180 0.051
multi organism reproductive process GO:0044703 262 0.051
reproductive process GO:0022414 372 0.051
regulation of cellular component organization GO:0051128 368 0.050
positive regulation of multicellular organismal process GO:0051240 387 0.049
rna biosynthetic process GO:0032774 380 0.047
rna metabolic process GO:0016070 406 0.044
cation transport GO:0006812 382 0.042
regulation of cell differentiation GO:0045595 320 0.041
carboxylic acid metabolic process GO:0019752 289 0.041
protein complex subunit organization GO:0071822 302 0.040
cellular catabolic process GO:0044248 295 0.039
positive regulation of developmental process GO:0051094 283 0.038
regulation of signal transduction GO:0009966 318 0.038
protein phosphorylation GO:0006468 345 0.038
catabolic process GO:0009056 351 0.037
organophosphate metabolic process GO:0019637 370 0.036
response to nutrient levels GO:0031667 370 0.036
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.036
nucleoside phosphate metabolic process GO:0006753 283 0.035
cellular component movement GO:0006928 248 0.034
regulation of molecular function GO:0065009 398 0.033
nucleic acid templated transcription GO:0097659 379 0.032
positive regulation of cellular biosynthetic process GO:0031328 295 0.032
cellular response to oxygen containing compound GO:1901701 386 0.032
purine nucleoside metabolic process GO:0042278 169 0.032
response to extracellular stimulus GO:0009991 380 0.032
positive regulation of biosynthetic process GO:0009891 319 0.031
apoptotic process GO:0006915 381 0.031
head development GO:0060322 247 0.031
homeostatic process GO:0042592 331 0.031
response to oxygen levels GO:0070482 265 0.031
organonitrogen compound catabolic process GO:1901565 179 0.030
regulation of rna metabolic process GO:0051252 391 0.030
regulation of transcription dna templated GO:0006355 374 0.030
macromolecular complex assembly GO:0065003 273 0.030
chromosome segregation GO:0007059 2 0.030
ion transmembrane transport GO:0034220 365 0.029
locomotion GO:0040011 237 0.029
nucleotide metabolic process GO:0009117 279 0.028
single organism catabolic process GO:0044712 283 0.028
nucleobase containing small molecule metabolic process GO:0055086 316 0.028
regulation of apoptotic process GO:0042981 335 0.027
carbohydrate metabolic process GO:0005975 130 0.027
cellular component biogenesis GO:0044085 368 0.027
cellular component assembly GO:0022607 360 0.027
regulation of rna biosynthetic process GO:2001141 381 0.027
regulation of multicellular organismal development GO:2000026 376 0.027
brain development GO:0007420 247 0.027
positive regulation of transcription dna templated GO:0045893 197 0.027
proteolysis GO:0006508 175 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
ribonucleotide metabolic process GO:0009259 231 0.026
transcription from rna polymerase ii promoter GO:0006366 252 0.026
intracellular signal transduction GO:0035556 314 0.026
cellular response to endogenous stimulus GO:0071495 377 0.026
neurological system process GO:0050877 219 0.026
single organism reproductive process GO:0044702 297 0.026
organic acid metabolic process GO:0006082 292 0.026
transcription dna templated GO:0006351 377 0.025
oxoacid metabolic process GO:0043436 290 0.025
regulation of neurogenesis GO:0050767 247 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
cell migration GO:0016477 197 0.024
central nervous system development GO:0007417 311 0.024
negative regulation of metabolic process GO:0009892 331 0.024
positive regulation of gene expression GO:0010628 244 0.024
organelle organization GO:0006996 266 0.024
cellular response to stress GO:0033554 269 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
cellular amino acid metabolic process GO:0006520 107 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
regulation of system process GO:0044057 208 0.023
intracellular transport GO:0046907 185 0.023
response to oxidative stress GO:0006979 186 0.023
response to metal ion GO:0010038 253 0.023
cell cell signaling GO:0007267 335 0.023
regulation of protein metabolic process GO:0051246 289 0.023
positive regulation of rna metabolic process GO:0051254 203 0.023
glycosyl compound catabolic process GO:1901658 126 0.022
regulation of phosphate metabolic process GO:0019220 349 0.022
neuron differentiation GO:0030182 368 0.022
metal ion transport GO:0030001 289 0.022
response to peptide hormone GO:0043434 278 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
cellular amine metabolic process GO:0044106 38 0.022
neuron development GO:0048666 286 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
spindle organization GO:0007051 2 0.021
chemical homeostasis GO:0048878 292 0.021
learning or memory GO:0007611 90 0.021
heterocycle catabolic process GO:0046700 167 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
establishment of protein localization GO:0045184 141 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.021
purine containing compound metabolic process GO:0072521 253 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
single organism intracellular transport GO:1902582 166 0.021
response to peptide GO:1901652 292 0.021
neuron projection development GO:0031175 273 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
positive regulation of signaling GO:0023056 270 0.020
multicellular organism reproduction GO:0032504 233 0.020
regulation of nucleic acid templated transcription GO:1903506 380 0.020
organophosphate catabolic process GO:0046434 148 0.020
vesicle mediated transport GO:0016192 181 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.019
cell growth GO:0016049 104 0.019
divalent inorganic cation homeostasis GO:0072507 165 0.019
response to hypoxia GO:0001666 231 0.019
regulation of phosphorus metabolic process GO:0051174 349 0.019
heart morphogenesis GO:0003007 3 0.019
negative regulation of cell communication GO:0010648 158 0.019
gamete generation GO:0007276 124 0.019
single organism biosynthetic process GO:0044711 342 0.019
growth GO:0040007 165 0.019
cellular homeostasis GO:0019725 252 0.019
cellular ketone metabolic process GO:0042180 51 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
cellular chemical homeostasis GO:0055082 247 0.019
secretion by cell GO:0032940 248 0.019
regulation of cell development GO:0060284 263 0.019
response to inorganic substance GO:0010035 377 0.018
single organism carbohydrate metabolic process GO:0044723 118 0.018
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
protein oligomerization GO:0051259 191 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
regulation of cell migration GO:0030334 128 0.018
response to decreased oxygen levels GO:0036293 237 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
anatomical structure morphogenesis GO:0009653 298 0.018
nitrogen compound transport GO:0071705 229 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
inorganic cation transmembrane transport GO:0098662 202 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
mitotic spindle organization GO:0007052 2 0.017
single organism cellular localization GO:1902580 102 0.017
synaptic transmission GO:0007268 235 0.017
cation homeostasis GO:0055080 195 0.017
protein modification by small protein conjugation or removal GO:0070647 35 0.017
transmembrane transport GO:0055085 412 0.017
multicellular organism growth GO:0035264 1 0.017
amine metabolic process GO:0009308 38 0.017
cation transmembrane transport GO:0098655 263 0.017
response to acid chemical GO:0001101 222 0.017
negative regulation of signaling GO:0023057 157 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
divalent metal ion transport GO:0070838 132 0.017
positive regulation of molecular function GO:0044093 230 0.017
metal ion homeostasis GO:0055065 186 0.017
divalent inorganic cation transport GO:0072511 134 0.017
carbohydrate derivative catabolic process GO:1901136 147 0.016
regulation of membrane potential GO:0042391 110 0.016
positive regulation of neuron projection development GO:0010976 99 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.016
regulation of programmed cell death GO:0043067 341 0.016
regulation of protein kinase activity GO:0045859 105 0.016
localization of cell GO:0051674 202 0.016
behavior GO:0007610 205 0.016
positive regulation of nucleic acid templated transcription GO:1903508 197 0.016
cellular calcium ion homeostasis GO:0006874 160 0.015
response to nutrient GO:0007584 248 0.015
cell projection organization GO:0030030 302 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
developmental process involved in reproduction GO:0003006 159 0.015
cell motility GO:0048870 202 0.015
regulation of phosphorylation GO:0042325 248 0.015
sexual reproduction GO:0019953 148 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
reproduction GO:0000003 245 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
axis specification GO:0009798 4 0.015
calcium ion transport GO:0006816 131 0.015
muscle system process GO:0003012 115 0.015
negative regulation of transport GO:0051051 136 0.014
response to alkaloid GO:0043279 132 0.014
secretion GO:0046903 307 0.014
negative regulation of signal transduction GO:0009968 83 0.014
response to insulin GO:0032868 133 0.014
macromolecule catabolic process GO:0009057 58 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
regulation of catalytic activity GO:0050790 304 0.014
regulation of nervous system development GO:0051960 264 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
positive regulation of signal transduction GO:0009967 175 0.014
embryonic pattern specification GO:0009880 1 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
negative regulation of cell cycle phase transition GO:1901988 4 0.014
response to cytokine GO:0034097 215 0.014
cell cycle GO:0007049 101 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
developmental growth GO:0048589 100 0.013
protein complex assembly GO:0006461 263 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
positive regulation of nervous system development GO:0051962 178 0.013
regulation of locomotion GO:0040012 148 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
purine containing compound catabolic process GO:0072523 138 0.013
positive regulation of transport GO:0051050 245 0.013
regulation of hormone levels GO:0010817 187 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
regulation of protein modification process GO:0031399 194 0.013
positive regulation of cell development GO:0010720 176 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
male gamete generation GO:0048232 99 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.013
peptidyl amino acid modification GO:0018193 126 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
positive regulation of cell communication GO:0010647 271 0.013
cellular cation homeostasis GO:0030003 180 0.013
aromatic compound catabolic process GO:0019439 168 0.013
nucleotide catabolic process GO:0009166 139 0.013
cardiac chamber development GO:0003205 1 0.013
liver development GO:0001889 90 0.013
calcium ion homeostasis GO:0055074 162 0.013
protein modification by small protein conjugation GO:0032446 31 0.013
protein catabolic process GO:0030163 30 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
lipid metabolic process GO:0006629 283 0.012
regulation of cellular localization GO:0060341 263 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
protein complex biogenesis GO:0070271 263 0.012
regulation of catabolic process GO:0009894 113 0.012
cellular protein localization GO:0034613 122 0.012
nucleoside catabolic process GO:0009164 126 0.012
development of primary sexual characteristics GO:0045137 107 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
regulation of metal ion transport GO:0010959 118 0.012
regulation of ion transport GO:0043269 245 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
ion homeostasis GO:0050801 212 0.012
muscle contraction GO:0006936 88 0.012
purine nucleoside monophosphate metabolic process GO:0009126 84 0.012
regulation of cell motility GO:2000145 131 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.012
response to ethanol GO:0045471 162 0.012
sex differentiation GO:0007548 113 0.012
cell cycle process GO:0022402 57 0.012
double strand break repair GO:0006302 1 0.012
ras protein signal transduction GO:0007265 29 0.012
single organism behavior GO:0044708 130 0.012
sex determination GO:0007530 2 0.012
regulation of synaptic transmission GO:0050804 141 0.012
cognition GO:0050890 92 0.011
response to estrogen GO:0043627 232 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
positive regulation of cell death GO:0010942 184 0.011
cardiovascular system development GO:0072358 134 0.011
cellular ion homeostasis GO:0006873 184 0.011
cell adhesion GO:0007155 110 0.011
circulatory system process GO:0003013 183 0.011
gonad development GO:0008406 104 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
heart development GO:0007507 72 0.011
protein localization GO:0008104 191 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.011
regulation of neuron projection development GO:0010975 161 0.011
protein dna complex disassembly GO:0032986 1 0.011
regulation of neuron differentiation GO:0045664 208 0.011
cytoplasmic transport GO:0016482 115 0.011
positive regulation of protein modification process GO:0031401 142 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
immune system process GO:0002376 204 0.011
nucleoside metabolic process GO:0009116 179 0.011
cellular response to external stimulus GO:0071496 118 0.011
negative regulation of gene expression GO:0010629 199 0.011
response to growth factor GO:0070848 189 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010
action potential GO:0001508 54 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
response to other organism GO:0051707 220 0.010
regulation of blood circulation GO:1903522 110 0.010
cytoskeleton organization GO:0007010 111 0.010
regulation of protein phosphorylation GO:0001932 183 0.010
memory GO:0007613 54 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
cellular response to lipid GO:0071396 201 0.010
regulation of secretion by cell GO:1903530 208 0.010
macromolecule localization GO:0033036 252 0.010
aging GO:0007568 241 0.010
negative regulation of cell death GO:0060548 229 0.010

Usp4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
musculoskeletal system disease DOID:17 0 0.010