Rattus norvegicus

29 known processes

Pold1

polymerase (DNA directed), delta 1, catalytic subunit

Pold1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 96 0.141
oxoacid metabolic process GO:0043436 290 0.124
nucleic acid templated transcription GO:0097659 379 0.094
organic acid metabolic process GO:0006082 292 0.093
regulation of rna biosynthetic process GO:2001141 381 0.088
carboxylic acid metabolic process GO:0019752 289 0.085
cellular catabolic process GO:0044248 295 0.085
Yeast
regulation of cellular component organization GO:0051128 368 0.073
negative regulation of cellular biosynthetic process GO:0031327 161 0.072
intracellular signal transduction GO:0035556 314 0.070
cellular amino acid metabolic process GO:0006520 107 0.070
catabolic process GO:0009056 351 0.069
Yeast
neuron differentiation GO:0030182 368 0.064
regulation of transcription dna templated GO:0006355 374 0.064
regulation of cell proliferation GO:0042127 359 0.063
regulation of nucleic acid templated transcription GO:1903506 380 0.061
negative regulation of metabolic process GO:0009892 331 0.061
organic cyclic compound catabolic process GO:1901361 175 0.060
Yeast
single organism biosynthetic process GO:0044711 342 0.060
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.059
organic substance catabolic process GO:1901575 316 0.058
Yeast
nucleoside phosphate metabolic process GO:0006753 283 0.057
protein complex assembly GO:0006461 263 0.057
regulation of molecular function GO:0065009 398 0.056
macromolecular complex subunit organization GO:0043933 339 0.052
transcription from rna polymerase ii promoter GO:0006366 252 0.052
transcription dna templated GO:0006351 377 0.052
chromosome segregation GO:0007059 2 0.052
regulation of programmed cell death GO:0043067 341 0.051
response to extracellular stimulus GO:0009991 380 0.049
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.049
aging GO:0007568 241 0.049
response to acid chemical GO:0001101 222 0.049
neuron projection development GO:0031175 273 0.047
coenzyme metabolic process GO:0006732 86 0.047
macromolecule localization GO:0033036 252 0.046
rna biosynthetic process GO:0032774 380 0.046
regulation of apoptotic process GO:0042981 335 0.045
cellular response to stress GO:0033554 269 0.045
Human
regulation of rna metabolic process GO:0051252 391 0.043
response to inorganic substance GO:0010035 377 0.043
single organism catabolic process GO:0044712 283 0.043
macromolecular complex assembly GO:0065003 273 0.043
ribonucleoside metabolic process GO:0009119 174 0.043
reproduction GO:0000003 245 0.042
response to amino acid GO:0043200 75 0.042
cellular response to oxygen containing compound GO:1901701 386 0.042
negative regulation of gene expression GO:0010629 199 0.041
rna metabolic process GO:0016070 406 0.041
Yeast
positive regulation of cellular protein metabolic process GO:0032270 167 0.041
positive regulation of rna biosynthetic process GO:1902680 197 0.040
positive regulation of apoptotic process GO:0043065 154 0.040
carbohydrate derivative metabolic process GO:1901135 346 0.040
neuron development GO:0048666 286 0.039
positive regulation of biosynthetic process GO:0009891 319 0.038
small gtpase mediated signal transduction GO:0007264 36 0.037
reproductive process GO:0022414 372 0.037
protein localization GO:0008104 191 0.037
oxidation reduction process GO:0055114 304 0.037
brain development GO:0007420 247 0.036
positive regulation of response to stimulus GO:0048584 285 0.036
single organism reproductive process GO:0044702 297 0.036
positive regulation of molecular function GO:0044093 230 0.036
regulation of cell differentiation GO:0045595 320 0.036
single organism organelle organization GO:1902589 180 0.036
purine containing compound metabolic process GO:0072521 253 0.035
negative regulation of rna metabolic process GO:0051253 123 0.035
regulation of phosphate metabolic process GO:0019220 349 0.035
regulation of nervous system development GO:0051960 264 0.035
aromatic compound catabolic process GO:0019439 168 0.034
Yeast
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.034
organelle organization GO:0006996 266 0.034
cellular lipid metabolic process GO:0044255 208 0.034
cell projection organization GO:0030030 302 0.033
regulation of neuron differentiation GO:0045664 208 0.033
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.033
regulation of multicellular organismal development GO:2000026 376 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.033
response to nutrient levels GO:0031667 370 0.033
head development GO:0060322 247 0.033
rhythmic process GO:0048511 156 0.032
organophosphate metabolic process GO:0019637 370 0.032
negative regulation of biosynthetic process GO:0009890 168 0.031
protein complex biogenesis GO:0070271 263 0.031
negative regulation of cell differentiation GO:0045596 99 0.031
response to hydrogen peroxide GO:0042542 89 0.031
regulation of phosphorus metabolic process GO:0051174 349 0.030
response to reactive oxygen species GO:0000302 120 0.030
cofactor metabolic process GO:0051186 95 0.030
programmed cell death GO:0012501 392 0.030
organonitrogen compound catabolic process GO:1901565 179 0.030
cellular component movement GO:0006928 248 0.030
heterocycle catabolic process GO:0046700 167 0.030
Yeast
regulation of neurogenesis GO:0050767 247 0.029
lipid metabolic process GO:0006629 283 0.029
positive regulation of cellular biosynthetic process GO:0031328 295 0.029
nucleobase containing small molecule metabolic process GO:0055086 316 0.029
apoptotic process GO:0006915 381 0.029
regulation of catalytic activity GO:0050790 304 0.029
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.029
nucleobase containing compound catabolic process GO:0034655 152 0.028
Yeast
organic acid biosynthetic process GO:0016053 83 0.028
response to vitamin GO:0033273 131 0.028
positive regulation of cell death GO:0010942 184 0.028
regulation of intracellular signal transduction GO:1902531 218 0.028
cellular amino acid biosynthetic process GO:0008652 32 0.028
regulation of phosphorylation GO:0042325 248 0.028
mitotic spindle organization GO:0007052 2 0.028
regulation of protein metabolic process GO:0051246 289 0.028
cellular nitrogen compound catabolic process GO:0044270 163 0.028
Yeast
response to nutrient GO:0007584 248 0.028
negative regulation of cell death GO:0060548 229 0.028
nucleoside metabolic process GO:0009116 179 0.028
carbohydrate derivative catabolic process GO:1901136 147 0.028
vesicle mediated transport GO:0016192 181 0.028
positive regulation of transcription dna templated GO:0045893 197 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
cardiac chamber development GO:0003205 1 0.027
cellular component assembly GO:0022607 360 0.027
negative regulation of cellular metabolic process GO:0031324 281 0.027
response to oxygen levels GO:0070482 265 0.027
ras protein signal transduction GO:0007265 29 0.027
protein complex subunit organization GO:0071822 302 0.026
cellular component biogenesis GO:0044085 368 0.026
response to wounding GO:0009611 254 0.026
cellular response to endogenous stimulus GO:0071495 377 0.026
response to peptide hormone GO:0043434 278 0.026
anatomical structure morphogenesis GO:0009653 298 0.026
small molecule biosynthetic process GO:0044283 124 0.026
response to corticosteroid GO:0031960 235 0.026
glycosyl compound metabolic process GO:1901657 182 0.026
positive regulation of catalytic activity GO:0043085 184 0.025
nucleoside triphosphate metabolic process GO:0009141 144 0.025
response to oxidative stress GO:0006979 186 0.025
nucleotide catabolic process GO:0009166 139 0.025
regulation of cell development GO:0060284 263 0.025
positive regulation of signaling GO:0023056 270 0.025
response to peptide GO:1901652 292 0.025
development of primary sexual characteristics GO:0045137 107 0.024
response to estradiol GO:0032355 164 0.024
response to growth factor GO:0070848 189 0.024
organophosphate catabolic process GO:0046434 148 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.024
cellular ketone metabolic process GO:0042180 51 0.024
positive regulation of programmed cell death GO:0043068 157 0.024
alpha amino acid metabolic process GO:1901605 71 0.024
nucleotide metabolic process GO:0009117 279 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
amine metabolic process GO:0009308 38 0.024
purine nucleotide metabolic process GO:0006163 229 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.024
cellular amine metabolic process GO:0044106 38 0.023
response to bacterium GO:0009617 200 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.023
central nervous system development GO:0007417 311 0.023
response to ketone GO:1901654 182 0.023
cellular response to growth factor stimulus GO:0071363 162 0.022
positive regulation of protein metabolic process GO:0051247 178 0.022
proteolysis GO:0006508 175 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
multicellular organism reproduction GO:0032504 233 0.022
ribonucleoside catabolic process GO:0042454 126 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.022
regulation of neuron projection development GO:0010975 161 0.022
response to glucocorticoid GO:0051384 223 0.022
protein phosphorylation GO:0006468 345 0.022
purine nucleoside catabolic process GO:0006152 124 0.021
regulation of signal transduction GO:0009966 318 0.021
peptidyl amino acid modification GO:0018193 126 0.021
regulation of response to stress GO:0080134 126 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
multi organism reproductive process GO:0044703 262 0.021
neuron projection morphogenesis GO:0048812 122 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.021
negative regulation of transcription dna templated GO:0045892 116 0.021
response to purine containing compound GO:0014074 126 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
single organism intracellular transport GO:1902582 166 0.021
response to external biotic stimulus GO:0043207 221 0.021
chromatin assembly or disassembly GO:0006333 1 0.021
organonitrogen compound biosynthetic process GO:1901566 167 0.020
glycosyl compound catabolic process GO:1901658 126 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.020
positive regulation of developmental process GO:0051094 283 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
response to toxic substance GO:0009636 133 0.020
nucleoside phosphate catabolic process GO:1901292 140 0.020
purine ribonucleotide catabolic process GO:0009154 136 0.020
negative regulation of cell communication GO:0010648 158 0.020
regulation of protein transport GO:0051223 68 0.020
response to metal ion GO:0010038 253 0.020
purine nucleoside metabolic process GO:0042278 169 0.020
positive regulation of cellular component organization GO:0051130 200 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
response to hypoxia GO:0001666 231 0.019
regulation of membrane potential GO:0042391 110 0.019
cytosolic calcium ion homeostasis GO:0051480 140 0.019
positive regulation of gene expression GO:0010628 244 0.019
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
nucleoside catabolic process GO:0009164 126 0.019
sexual reproduction GO:0019953 148 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
protein transport GO:0015031 132 0.019
gamete generation GO:0007276 124 0.019
positive regulation of nervous system development GO:0051962 178 0.019
homeostatic process GO:0042592 331 0.019
Human
limb morphogenesis GO:0035108 4 0.019
positive regulation of cell communication GO:0010647 271 0.019
response to alkaloid GO:0043279 132 0.019
positive regulation of transport GO:0051050 245 0.018
histone h3 k9 methylation GO:0051567 1 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
cellular response to peptide hormone stimulus GO:0071375 120 0.018
learning or memory GO:0007611 90 0.018
meiotic cell cycle process GO:1903046 3 0.018
gastrulation GO:0007369 2 0.018
response to lipopolysaccharide GO:0032496 191 0.018
regulation of cellular localization GO:0060341 263 0.018
neurological system process GO:0050877 219 0.018
cell morphogenesis GO:0000902 142 0.018
regulation of proteasomal protein catabolic process GO:0061136 4 0.018
centrosome organization GO:0051297 1 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
sex differentiation GO:0007548 113 0.018
microtubule organizing center organization GO:0031023 1 0.018
purine nucleotide catabolic process GO:0006195 136 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
response to estrogen GO:0043627 232 0.017
cellular response to organic cyclic compound GO:0071407 202 0.017
cellular response to acid chemical GO:0071229 75 0.017
circulatory system development GO:0072359 134 0.017
developmental process involved in reproduction GO:0003006 159 0.017
purine nucleoside triphosphate catabolic process GO:0009146 122 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
muscle system process GO:0003012 115 0.017
behavior GO:0007610 205 0.017
positive regulation of catabolic process GO:0009896 78 0.017
cell morphogenesis involved in differentiation GO:0000904 119 0.017
gland development GO:0048732 155 0.017
purine containing compound catabolic process GO:0072523 138 0.017
response to decreased oxygen levels GO:0036293 237 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.016
positive regulation of signal transduction GO:0009967 175 0.016
regulation of protein modification process GO:0031399 194 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
ribonucleoside triphosphate catabolic process GO:0009203 122 0.016
synaptic transmission GO:0007268 235 0.016
ribonucleotide catabolic process GO:0009261 136 0.016
response to molecule of bacterial origin GO:0002237 194 0.016
regulation of kinase activity GO:0043549 117 0.016
locomotion GO:0040011 237 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.016
sulfur compound metabolic process GO:0006790 70 0.016
cellular component morphogenesis GO:0032989 155 0.016
nucleoside triphosphate catabolic process GO:0009143 123 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
negative regulation of developmental process GO:0051093 125 0.016
positive regulation of protein modification process GO:0031401 142 0.016
negative regulation of cell cycle phase transition GO:1901988 4 0.016
tube development GO:0035295 89 0.016
regeneration GO:0031099 163 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
circadian rhythm GO:0007623 88 0.015
cellular homeostasis GO:0019725 252 0.015
regulation of reactive oxygen species metabolic process GO:2000377 26 0.015
reproductive system development GO:0061458 128 0.015
spindle organization GO:0007051 2 0.015
ion homeostasis GO:0050801 212 0.015
Human
positive regulation of protein phosphorylation GO:0001934 135 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.015
positive regulation of cellular catabolic process GO:0031331 71 0.015
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
positive regulation of organelle organization GO:0010638 48 0.015
intracellular transport GO:0046907 185 0.015
purine ribonucleoside catabolic process GO:0046130 124 0.015
heart morphogenesis GO:0003007 3 0.015
response to other organism GO:0051707 220 0.015
regulation of organelle organization GO:0033043 80 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
gonad development GO:0008406 104 0.014
negative regulation of signaling GO:0023057 157 0.014
neural crest cell development GO:0014032 2 0.014
regulation of hydrolase activity GO:0051336 143 0.014
regulation of chromosome segregation GO:0051983 1 0.014
regulation of purine nucleotide metabolic process GO:1900542 115 0.014
cellular macromolecular complex assembly GO:0034622 58 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
anterior posterior pattern specification GO:0009952 1 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
chemical homeostasis GO:0048878 292 0.014
Human
negative regulation of apoptotic process GO:0043066 181 0.014
cellular protein localization GO:0034613 122 0.014
ovulation cycle process GO:0022602 50 0.014
cellular modified amino acid metabolic process GO:0006575 61 0.014
cell adhesion GO:0007155 110 0.014
cognition GO:0050890 92 0.014
single organism cellular localization GO:1902580 102 0.014
response to radiation GO:0009314 137 0.014
regulation of cellular catabolic process GO:0031329 101 0.014
negative regulation of signal transduction GO:0009968 83 0.013
defense response GO:0006952 194 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
establishment of protein localization GO:0045184 141 0.013
regulation of histone h3 k9 methylation GO:0051570 1 0.013
response to ethanol GO:0045471 162 0.013
bmp signaling pathway GO:0030509 4 0.013
regulation of cell projection organization GO:0031344 175 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
cellular ion homeostasis GO:0006873 184 0.013
embryonic pattern specification GO:0009880 1 0.013
calcium ion homeostasis GO:0055074 162 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
transmission of nerve impulse GO:0019226 42 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
response to organophosphorus GO:0046683 102 0.013
cell cell signaling GO:0007267 335 0.013
axis specification GO:0009798 4 0.013
carboxylic acid biosynthetic process GO:0046394 83 0.013
cellular cation homeostasis GO:0030003 180 0.013
activation of cysteine type endopeptidase activity GO:0097202 4 0.013
cell migration GO:0016477 197 0.013
negative regulation of molecular function GO:0044092 133 0.013
double strand break repair GO:0006302 1 0.013
secretion GO:0046903 307 0.013
guanosine containing compound metabolic process GO:1901068 74 0.012
nucleocytoplasmic transport GO:0006913 48 0.012
single organism behavior GO:0044708 130 0.012
cytoplasmic transport GO:0016482 115 0.012
response to activity GO:0014823 73 0.012
histone h3 k9 modification GO:0061647 2 0.012
pteridine containing compound metabolic process GO:0042558 14 0.012
regulation of establishment of protein localization GO:0070201 69 0.012
cellular response to lipid GO:0071396 201 0.012
protein localization to organelle GO:0033365 57 0.012
mitotic sister chromatid separation GO:0051306 1 0.012
meiosis i GO:0007127 2 0.012
muscle structure development GO:0061061 87 0.012
cell projection morphogenesis GO:0048858 123 0.012
regulation of protein kinase activity GO:0045859 105 0.012
response to biotic stimulus GO:0009607 226 0.012
maintenance of location GO:0051235 17 0.012
axon development GO:0061564 96 0.012
cardiovascular system development GO:0072358 134 0.012
positive regulation of secretion GO:0051047 140 0.012
eye morphogenesis GO:0048592 4 0.012
response to axon injury GO:0048678 59 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
ion transmembrane transport GO:0034220 365 0.012
dna integrity checkpoint GO:0031570 2 0.012
regulation of dendrite development GO:0050773 59 0.012
chromatin modification GO:0016568 33 0.012
muscle tissue morphogenesis GO:0060415 1 0.012
negative regulation of transport GO:0051051 136 0.012
embryonic appendage morphogenesis GO:0035113 4 0.012
chromosome organization GO:0051276 36 0.012
alpha amino acid biosynthetic process GO:1901607 23 0.011
negative regulation of neuron differentiation GO:0045665 62 0.011
reproductive structure development GO:0048608 128 0.011
hepaticobiliary system development GO:0061008 90 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
biological adhesion GO:0022610 110 0.011
dna replication GO:0006260 37 0.011
response to temperature stimulus GO:0009266 94 0.011
cell part morphogenesis GO:0032990 123 0.011
rho protein signal transduction GO:0007266 11 0.011
cellular chemical homeostasis GO:0055082 247 0.011
dna packaging GO:0006323 4 0.011
regulation of cellular response to stress GO:0080135 49 0.011
cellular macromolecule localization GO:0070727 122 0.011
embryonic hindlimb morphogenesis GO:0035116 2 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
inflammatory response GO:0006954 150 0.011
positive regulation of cell development GO:0010720 176 0.011
ovulation cycle GO:0042698 67 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
cellular response to external stimulus GO:0071496 118 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
metal ion homeostasis GO:0055065 186 0.011
protein maturation GO:0051604 68 0.011
tissue development GO:0009888 252 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
regulation of system process GO:0044057 208 0.011
cation homeostasis GO:0055080 195 0.011
protein oligomerization GO:0051259 191 0.011
negative regulation of nervous system development GO:0051961 79 0.011
regulation of cell cycle GO:0051726 73 0.011
immune system process GO:0002376 204 0.010
regulation of secretion by cell GO:1903530 208 0.010
cell activation GO:0001775 97 0.010
negative regulation of chromosome organization GO:2001251 1 0.010
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.010
negative regulation of neurogenesis GO:0050768 78 0.010
g protein coupled receptor signaling pathway GO:0007186 242 0.010
positive regulation of cellular component movement GO:0051272 102 0.010
secretion by cell GO:0032940 248 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
male gamete generation GO:0048232 99 0.010
protein targeting GO:0006605 61 0.010
histone methylation GO:0016571 3 0.010
response to camp GO:0051591 91 0.010
cellular response to metal ion GO:0071248 55 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
endocytosis GO:0006897 84 0.010
response to monosaccharide GO:0034284 159 0.010
cell cycle GO:0007049 101 0.010

Pold1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
disease of metabolism DOID:0014667 0 0.012
cancer DOID:162 0 0.012
Human
disease of cellular proliferation DOID:14566 0 0.012
Human