Rattus norvegicus

0 known processes

Phc1

polyhomeotic homolog 1 (Drosophila)

Phc1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intracellular signal transduction GO:0035556 314 0.177
positive regulation of catalytic activity GO:0043085 184 0.163
catabolic process GO:0009056 351 0.156
cellular catabolic process GO:0044248 295 0.153
positive regulation of phosphate metabolic process GO:0045937 262 0.121
rna biosynthetic process GO:0032774 380 0.120
regulation of nucleic acid templated transcription GO:1903506 380 0.108
regulation of transcription dna templated GO:0006355 374 0.104
regulation of signal transduction GO:0009966 318 0.100
regulation of phosphorus metabolic process GO:0051174 349 0.100
regulation of phosphate metabolic process GO:0019220 349 0.095
positive regulation of phosphorus metabolic process GO:0010562 262 0.084
regulation of transferase activity GO:0051338 123 0.081
nucleoside phosphate metabolic process GO:0006753 283 0.081
organic substance catabolic process GO:1901575 316 0.080
aromatic compound catabolic process GO:0019439 168 0.080
protein phosphorylation GO:0006468 345 0.077
regulation of intracellular signal transduction GO:1902531 218 0.074
regulation of molecular function GO:0065009 398 0.074
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.073
organic cyclic compound catabolic process GO:1901361 175 0.072
regulation of phosphorylation GO:0042325 248 0.071
positive regulation of transcription dna templated GO:0045893 197 0.070
regulation of protein phosphorylation GO:0001932 183 0.070
signal transduction by phosphorylation GO:0023014 144 0.068
purine nucleotide metabolic process GO:0006163 229 0.068
single organism catabolic process GO:0044712 283 0.068
organophosphate catabolic process GO:0046434 148 0.066
reproductive process GO:0022414 372 0.064
nucleotide catabolic process GO:0009166 139 0.064
regulation of cellular catabolic process GO:0031329 101 0.064
nucleic acid templated transcription GO:0097659 379 0.064
purine ribonucleotide catabolic process GO:0009154 136 0.063
transcription dna templated GO:0006351 377 0.062
transcription from rna polymerase ii promoter GO:0006366 252 0.060
positive regulation of molecular function GO:0044093 230 0.059
regulation of cellular localization GO:0060341 263 0.059
regulation of mapk cascade GO:0043408 116 0.058
protein complex subunit organization GO:0071822 302 0.057
positive regulation of phosphorylation GO:0042327 177 0.057
neuron development GO:0048666 286 0.057
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.057
protein complex biogenesis GO:0070271 263 0.054
regulation of catabolic process GO:0009894 113 0.054
organophosphate metabolic process GO:0019637 370 0.051
regulation of cellular protein metabolic process GO:0032268 267 0.051
regulation of catalytic activity GO:0050790 304 0.050
heterocycle catabolic process GO:0046700 167 0.049
mapk cascade GO:0000165 140 0.048
regulation of rna metabolic process GO:0051252 391 0.048
regulation of protein metabolic process GO:0051246 289 0.048
response to extracellular stimulus GO:0009991 380 0.047
nucleoside triphosphate catabolic process GO:0009143 123 0.047
positive regulation of cellular protein metabolic process GO:0032270 167 0.047
purine nucleotide catabolic process GO:0006195 136 0.046
ribonucleotide catabolic process GO:0009261 136 0.044
nucleobase containing small molecule metabolic process GO:0055086 316 0.044
carbohydrate derivative catabolic process GO:1901136 147 0.044
nucleoside phosphate catabolic process GO:1901292 140 0.044
positive regulation of protein phosphorylation GO:0001934 135 0.043
ribose phosphate metabolic process GO:0019693 235 0.043
programmed cell death GO:0012501 392 0.042
single organism reproductive process GO:0044702 297 0.042
purine nucleoside triphosphate catabolic process GO:0009146 122 0.042
regulation of protein kinase activity GO:0045859 105 0.042
regulation of protein modification process GO:0031399 194 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.041
glycosyl compound catabolic process GO:1901658 126 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.040
positive regulation of cellular catabolic process GO:0031331 71 0.040
aging GO:0007568 241 0.040
ribonucleoside catabolic process GO:0042454 126 0.039
nucleobase containing compound catabolic process GO:0034655 152 0.039
positive regulation of biosynthetic process GO:0009891 319 0.039
positive regulation of rna biosynthetic process GO:1902680 197 0.039
positive regulation of cellular biosynthetic process GO:0031328 295 0.039
neuron projection development GO:0031175 273 0.039
neuron differentiation GO:0030182 368 0.038
purine containing compound metabolic process GO:0072521 253 0.038
ribonucleotide metabolic process GO:0009259 231 0.037
organonitrogen compound catabolic process GO:1901565 179 0.037
regulation of proteasomal protein catabolic process GO:0061136 4 0.037
positive regulation of signaling GO:0023056 270 0.037
response to carbohydrate GO:0009743 183 0.036
positive regulation of signal transduction GO:0009967 175 0.036
positive regulation of gene expression GO:0010628 244 0.036
positive regulation of protein modification process GO:0031401 142 0.036
cell projection organization GO:0030030 302 0.036
regulation of multicellular organismal development GO:2000026 376 0.036
cellular response to oxygen containing compound GO:1901701 386 0.036
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.036
purine containing compound catabolic process GO:0072523 138 0.036
cardiovascular system development GO:0072358 134 0.036
response to nutrient levels GO:0031667 370 0.036
nucleoside triphosphate metabolic process GO:0009141 144 0.035
positive regulation of nucleic acid templated transcription GO:1903508 197 0.035
positive regulation of transport GO:0051050 245 0.035
intracellular transport GO:0046907 185 0.035
regulation of nervous system development GO:0051960 264 0.035
response to peptide GO:1901652 292 0.034
cellular component assembly GO:0022607 360 0.034
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.034
oxoacid metabolic process GO:0043436 290 0.033
positive regulation of nucleotide metabolic process GO:0045981 91 0.033
regulation of cellular component organization GO:0051128 368 0.032
response to peptide hormone GO:0043434 278 0.032
positive regulation of response to stimulus GO:0048584 285 0.032
nucleotide metabolic process GO:0009117 279 0.032
regulation of gtpase activity GO:0043087 57 0.032
nucleoside catabolic process GO:0009164 126 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.031
secretion GO:0046903 307 0.031
single organism intracellular transport GO:1902582 166 0.031
cellular component biogenesis GO:0044085 368 0.031
cellular response to endogenous stimulus GO:0071495 377 0.031
neuron projection morphogenesis GO:0048812 122 0.031
macromolecular complex assembly GO:0065003 273 0.031
glycosyl compound metabolic process GO:1901657 182 0.031
regulation of cell differentiation GO:0045595 320 0.030
purine nucleoside catabolic process GO:0006152 124 0.030
tissue development GO:0009888 252 0.030
protein transport GO:0015031 132 0.030
purine nucleoside triphosphate metabolic process GO:0009144 141 0.030
protein complex assembly GO:0006461 263 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.029
cellular ketone metabolic process GO:0042180 51 0.029
organic acid metabolic process GO:0006082 292 0.029
positive regulation of protein kinase activity GO:0045860 73 0.029
macromolecular complex subunit organization GO:0043933 339 0.029
Human
dna metabolic process GO:0006259 96 0.029
macromolecule localization GO:0033036 252 0.029
ribonucleoside triphosphate catabolic process GO:0009203 122 0.029
negative regulation of cellular metabolic process GO:0031324 281 0.028
small gtpase mediated signal transduction GO:0007264 36 0.028
positive regulation of cell death GO:0010942 184 0.028
positive regulation of protein metabolic process GO:0051247 178 0.028
ribonucleoside triphosphate metabolic process GO:0009199 141 0.028
response to molecule of bacterial origin GO:0002237 194 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.027
positive regulation of cell communication GO:0010647 271 0.027
negative regulation of biosynthetic process GO:0009890 168 0.027
guanosine containing compound catabolic process GO:1901069 71 0.027
negative regulation of signal transduction GO:0009968 83 0.027
immune system process GO:0002376 204 0.027
ras protein signal transduction GO:0007265 29 0.027
negative regulation of metabolic process GO:0009892 331 0.027
nucleocytoplasmic transport GO:0006913 48 0.027
nucleoside metabolic process GO:0009116 179 0.027
carboxylic acid metabolic process GO:0019752 289 0.027
regulation of hydrolase activity GO:0051336 143 0.026
positive regulation of programmed cell death GO:0043068 157 0.026
positive regulation of nervous system development GO:0051962 178 0.026
positive regulation of rna metabolic process GO:0051254 203 0.026
regulation of nucleotide metabolic process GO:0006140 117 0.026
purine nucleoside metabolic process GO:0042278 169 0.025
regulation of purine nucleotide metabolic process GO:1900542 115 0.025
guanosine containing compound metabolic process GO:1901068 74 0.025
negative regulation of cell communication GO:0010648 158 0.025
response to external biotic stimulus GO:0043207 221 0.025
negative regulation of response to stimulus GO:0048585 155 0.025
developmental process involved in reproduction GO:0003006 159 0.025
response to monosaccharide GO:0034284 159 0.024
apoptotic process GO:0006915 381 0.024
purine ribonucleoside catabolic process GO:0046130 124 0.024
response to bacterium GO:0009617 200 0.024
multi organism reproductive process GO:0044703 262 0.024
lipid metabolic process GO:0006629 283 0.024
regulation of kinase activity GO:0043549 117 0.024
cellular nitrogen compound catabolic process GO:0044270 163 0.024
negative regulation of transcription dna templated GO:0045892 116 0.024
growth GO:0040007 165 0.024
response to acid chemical GO:0001101 222 0.024
response to cytokine GO:0034097 215 0.024
protein localization GO:0008104 191 0.023
positive regulation of developmental process GO:0051094 283 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
gtp metabolic process GO:0046039 72 0.023
regulation of programmed cell death GO:0043067 341 0.023
response to inorganic substance GO:0010035 377 0.023
purine ribonucleoside metabolic process GO:0046128 168 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
regulation of cell development GO:0060284 263 0.023
single organism organelle organization GO:1902589 180 0.023
Human
anion transport GO:0006820 178 0.023
regulation of neurogenesis GO:0050767 247 0.022
regulation of apoptotic process GO:0042981 335 0.022
protein oligomerization GO:0051259 191 0.022
cellular macromolecule localization GO:0070727 122 0.022
positive regulation of apoptotic process GO:0043065 154 0.022
negative regulation of cellular biosynthetic process GO:0031327 161 0.022
rna metabolic process GO:0016070 406 0.022
cell cell signaling GO:0007267 335 0.022
cellular response to lipid GO:0071396 201 0.022
negative regulation of signaling GO:0023057 157 0.021
regulation of small gtpase mediated signal transduction GO:0051056 48 0.021
cellular amine metabolic process GO:0044106 38 0.021
positive regulation of catabolic process GO:0009896 78 0.021
multicellular organism reproduction GO:0032504 233 0.021
regulation of rna biosynthetic process GO:2001141 381 0.021
gastrulation GO:0007369 2 0.021
gtp catabolic process GO:0006184 71 0.021
response to temperature stimulus GO:0009266 94 0.021
positive regulation of cell differentiation GO:0045597 217 0.021
cellular protein localization GO:0034613 122 0.021
response to lipopolysaccharide GO:0032496 191 0.020
positive regulation of intracellular signal transduction GO:1902533 138 0.020
reproduction GO:0000003 245 0.020
cellular response to nitrogen compound GO:1901699 210 0.020
negative regulation of developmental process GO:0051093 125 0.020
regulation of nucleotide catabolic process GO:0030811 65 0.020
establishment of protein localization GO:0045184 141 0.020
positive regulation of transferase activity GO:0051347 81 0.020
cytoplasmic transport GO:0016482 115 0.020
regulation of neuron differentiation GO:0045664 208 0.020
proteolysis GO:0006508 175 0.020
anterior posterior pattern specification GO:0009952 1 0.020
positive regulation of kinase activity GO:0033674 77 0.020
positive regulation of neurogenesis GO:0050769 165 0.020
negative regulation of cell proliferation GO:0008285 119 0.020
positive regulation of nucleoside metabolic process GO:0045979 55 0.019
signal release GO:0023061 145 0.019
cellular amino acid metabolic process GO:0006520 107 0.019
organelle organization GO:0006996 266 0.019
Human
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.019
response to metal ion GO:0010038 253 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
protein targeting GO:0006605 61 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
ribonucleoside metabolic process GO:0009119 174 0.019
organic acid transport GO:0015849 116 0.019
regulation of neuron projection development GO:0010975 161 0.019
sexual reproduction GO:0019953 148 0.019
positive regulation of neuron differentiation GO:0045666 126 0.019
regulation of neuron death GO:1901214 115 0.018
regulation of cell proliferation GO:0042127 359 0.018
establishment of protein localization to organelle GO:0072594 44 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
negative regulation of cell death GO:0060548 229 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.018
regulation of protein transport GO:0051223 68 0.018
epithelium development GO:0060429 96 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.017
regulation of protein localization GO:0032880 81 0.017
ion transmembrane transport GO:0034220 365 0.017
synaptic transmission GO:0007268 235 0.017
cellular response to molecule of bacterial origin GO:0071219 56 0.017
positive regulation of gtp catabolic process GO:0033126 48 0.017
response to oxidative stress GO:0006979 186 0.017
cell growth GO:0016049 104 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.017
response to oxygen levels GO:0070482 265 0.017
central nervous system development GO:0007417 311 0.017
cell migration GO:0016477 197 0.017
positive regulation of secretion GO:0051047 140 0.017
cell type specific apoptotic process GO:0097285 134 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.016
immune response GO:0006955 104 0.016
locomotion GO:0040011 237 0.016
muscle structure development GO:0061061 87 0.016
enzyme linked receptor protein signaling pathway GO:0007167 116 0.016
negative regulation of organ growth GO:0046621 3 0.016
nuclear transport GO:0051169 49 0.016
regulation of growth GO:0040008 105 0.016
cellular response to stress GO:0033554 269 0.016
response to corticosteroid GO:0031960 235 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
transmembrane transport GO:0055085 412 0.016
response to heat GO:0009408 60 0.016
circulatory system development GO:0072359 134 0.016
single organism carbohydrate metabolic process GO:0044723 118 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
regulation of establishment of protein localization GO:0070201 69 0.016
regulation of secretion by cell GO:1903530 208 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
regulation of map kinase activity GO:0043405 53 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.015
regulation of ras protein signal transduction GO:0046578 45 0.015
single organism nuclear import GO:1902593 35 0.015
insulin like growth factor receptor signaling pathway GO:0048009 3 0.015
cellular component movement GO:0006928 248 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.015
regulation of protein serine threonine kinase activity GO:0071900 64 0.015
tube development GO:0035295 89 0.015
gamete generation GO:0007276 124 0.015
regulation of secretion GO:0051046 224 0.015
negative regulation of rna metabolic process GO:0051253 123 0.015
protein localization to organelle GO:0033365 57 0.015
cell part morphogenesis GO:0032990 123 0.015
chromatin modification GO:0016568 33 0.015
Human
response to hexose GO:0009746 144 0.015
muscle tissue development GO:0060537 58 0.015
cellular lipid metabolic process GO:0044255 208 0.015
regulation of hormone levels GO:0010817 187 0.015
response to decreased oxygen levels GO:0036293 237 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
regulation of purine nucleotide catabolic process GO:0033121 65 0.015
positive regulation of mapk cascade GO:0043410 92 0.014
regulation of ion transport GO:0043269 245 0.014
positive regulation of nucleotide catabolic process GO:0030813 53 0.014
secretion by cell GO:0032940 248 0.014
regulation of nucleoside metabolic process GO:0009118 66 0.014
response to glucocorticoid GO:0051384 223 0.014
chemical homeostasis GO:0048878 292 0.014
brain development GO:0007420 247 0.014
amine metabolic process GO:0009308 38 0.014
homeostatic process GO:0042592 331 0.014
negative regulation of gene expression GO:0010629 199 0.014
cell projection morphogenesis GO:0048858 123 0.014
anatomical structure formation involved in morphogenesis GO:0048646 83 0.014
response to insulin GO:0032868 133 0.014
axon development GO:0061564 96 0.014
cell morphogenesis GO:0000902 142 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
regeneration GO:0031099 163 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
morphogenesis of embryonic epithelium GO:0016331 3 0.014
regulation of ras gtpase activity GO:0032318 32 0.014
stress activated protein kinase signaling cascade GO:0031098 37 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
cellular response to cytokine stimulus GO:0071345 127 0.013
regulation of cellular component biogenesis GO:0044087 86 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
positive regulation of hydrolase activity GO:0051345 86 0.013
establishment of tissue polarity GO:0007164 2 0.013
positive regulation of cell development GO:0010720 176 0.013
chemotaxis GO:0006935 66 0.013
histone h3 acetylation GO:0043966 2 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
protein heterooligomerization GO:0051291 89 0.013
response to tumor necrosis factor GO:0034612 56 0.013
organic anion transport GO:0015711 132 0.013
developmental growth GO:0048589 100 0.013
carbohydrate metabolic process GO:0005975 130 0.013
response to glucose GO:0009749 136 0.013
nitrogen compound transport GO:0071705 229 0.013
negative regulation of molecular function GO:0044092 133 0.013
inflammatory response GO:0006954 150 0.013
cellular homeostasis GO:0019725 252 0.013
dendrite development GO:0016358 72 0.012
response to other organism GO:0051707 220 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
muscle system process GO:0003012 115 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
regulation of fat cell differentiation GO:0045598 3 0.012
negative regulation of innate immune response GO:0045824 4 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
axis specification GO:0009798 4 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
lipid transport GO:0006869 61 0.012
chromosome organization GO:0051276 36 0.012
Human
negative regulation of protein metabolic process GO:0051248 114 0.012
neuronal action potential GO:0019228 35 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
regulation of response to stress GO:0080134 126 0.012
response to nutrient GO:0007584 248 0.012
neuron apoptotic process GO:0051402 88 0.011
actin filament based process GO:0030029 86 0.011
monocarboxylic acid transport GO:0015718 52 0.011
organ formation GO:0048645 3 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
hexose metabolic process GO:0019318 58 0.011
response to biotic stimulus GO:0009607 226 0.011
response to hypoxia GO:0001666 231 0.011
regulation of gtp catabolic process GO:0033124 58 0.011
regulation of intracellular transport GO:0032386 65 0.011
carboxylic acid transport GO:0046942 115 0.011
regulation of rab protein signal transduction GO:0032483 3 0.011
positive regulation of ras gtpase activity GO:0032320 28 0.011
activation of protein kinase activity GO:0032147 47 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
heart development GO:0007507 72 0.011
autophagy GO:0006914 19 0.011
transmission of nerve impulse GO:0019226 42 0.011
cell fate determination GO:0001709 2 0.011
response to hydrogen peroxide GO:0042542 89 0.011
nuclear import GO:0051170 35 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
cellular component morphogenesis GO:0032989 155 0.011
reproductive structure development GO:0048608 128 0.011
organ growth GO:0035265 24 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
multicellular organism growth GO:0035264 1 0.011
positive regulation of neuron migration GO:2001224 2 0.011
peptidyl amino acid modification GO:0018193 126 0.011
cellular response to peptide GO:1901653 133 0.011
regulation of cell projection organization GO:0031344 175 0.011
positive regulation of map kinase activity GO:0043406 46 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
multi multicellular organism process GO:0044706 138 0.011
intracellular protein transport GO:0006886 79 0.010
protein import into nucleus GO:0006606 35 0.010
female pregnancy GO:0007565 122 0.010
tube formation GO:0035148 3 0.010
single organism biosynthetic process GO:0044711 342 0.010
protein homooligomerization GO:0051260 91 0.010
actin cytoskeleton organization GO:0030036 73 0.010
peptide transport GO:0015833 97 0.010

Phc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
sensory system disease DOID:0050155 0 0.010