Rattus norvegicus

55 known processes

Mark1

MAP/microtubule affinity-regulating kinase 1

Mark1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of rna metabolic process GO:0051252 391 0.183
Rat
regulation of transcription dna templated GO:0006355 374 0.128
Rat
transcription dna templated GO:0006351 377 0.107
Rat
organelle organization GO:0006996 266 0.091
rna metabolic process GO:0016070 406 0.085
Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.085
Rat
neuron differentiation GO:0030182 368 0.077
intracellular transport GO:0046907 185 0.072
nucleic acid templated transcription GO:0097659 379 0.068
Rat
negative regulation of rna biosynthetic process GO:1902679 118 0.067
Rat
apoptotic process GO:0006915 381 0.067
cell projection organization GO:0030030 302 0.061
regulation of nucleic acid templated transcription GO:1903506 380 0.060
Rat
neuron development GO:0048666 286 0.059
reproduction GO:0000003 245 0.056
Worm
alpha amino acid metabolic process GO:1901605 71 0.052
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.051
Rat
cation transport GO:0006812 382 0.049
Rat
cytoskeleton organization GO:0007010 111 0.049
rna biosynthetic process GO:0032774 380 0.048
Rat
positive regulation of cell proliferation GO:0008284 249 0.048
cellular component biogenesis GO:0044085 368 0.047
cellular component assembly GO:0022607 360 0.047
cell morphogenesis GO:0000902 142 0.045
neuron projection development GO:0031175 273 0.044
cell cell signaling GO:0007267 335 0.044
neuron projection morphogenesis GO:0048812 122 0.043
macromolecular complex subunit organization GO:0043933 339 0.042
negative regulation of transcription dna templated GO:0045892 116 0.040
Rat
protein localization GO:0008104 191 0.039
Worm
behavior GO:0007610 205 0.039
regulation of cellular component organization GO:0051128 368 0.038
Rat
response to wounding GO:0009611 254 0.038
carbohydrate derivative metabolic process GO:1901135 346 0.037
axon development GO:0061564 96 0.037
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.037
Rat
response to oxygen levels GO:0070482 265 0.037
protein complex subunit organization GO:0071822 302 0.037
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.037
Rat
protein transport GO:0015031 132 0.036
negative regulation of macromolecule metabolic process GO:0010605 260 0.036
Rat
single organism intracellular transport GO:1902582 166 0.036
positive regulation of biosynthetic process GO:0009891 319 0.035
regulation of synaptic transmission GO:0050804 141 0.035
cell part morphogenesis GO:0032990 123 0.035
central nervous system development GO:0007417 311 0.035
regulation of proteasomal protein catabolic process GO:0061136 4 0.034
head development GO:0060322 247 0.033
organonitrogen compound biosynthetic process GO:1901566 167 0.033
macromolecule localization GO:0033036 252 0.033
Worm
protein complex biogenesis GO:0070271 263 0.033
anterior posterior pattern specification GO:0009952 1 0.033
synaptic transmission GO:0007268 235 0.033
programmed cell death GO:0012501 392 0.032
cellular component movement GO:0006928 248 0.032
organic substance catabolic process GO:1901575 316 0.031
single organism biosynthetic process GO:0044711 342 0.031
cellular component morphogenesis GO:0032989 155 0.030
regulation of rna biosynthetic process GO:2001141 381 0.030
Rat
response to extracellular stimulus GO:0009991 380 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.030
macromolecular complex assembly GO:0065003 273 0.030
cellular homeostasis GO:0019725 252 0.030
negative regulation of cellular metabolic process GO:0031324 281 0.030
Rat
cellular catabolic process GO:0044248 295 0.030
negative regulation of metabolic process GO:0009892 331 0.029
Rat
regulation of multicellular organismal development GO:2000026 376 0.028
Worm
single organism organelle organization GO:1902589 180 0.027
developmental process involved in reproduction GO:0003006 159 0.027
Worm
synaptic growth at neuromuscular junction GO:0051124 1 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
tissue development GO:0009888 252 0.027
anatomical structure morphogenesis GO:0009653 298 0.026
single organism reproductive process GO:0044702 297 0.026
Worm
organophosphate metabolic process GO:0019637 370 0.026
embryonic skeletal system development GO:0048706 3 0.026
positive regulation of transcription dna templated GO:0045893 197 0.026
response to hypoxia GO:0001666 231 0.026
protein oligomerization GO:0051259 191 0.026
multicellular organismal reproductive process GO:0048609 233 0.026
cellular response to insulin stimulus GO:0032869 81 0.025
transcription from rna polymerase ii promoter GO:0006366 252 0.025
Rat
regulation of cell projection organization GO:0031344 175 0.025
chemical homeostasis GO:0048878 292 0.025
negative regulation of rna metabolic process GO:0051253 123 0.025
Rat
axis specification GO:0009798 4 0.025
regulation of anatomical structure morphogenesis GO:0022603 141 0.025
cellular response to stress GO:0033554 269 0.025
cellular response to nitrogen compound GO:1901699 210 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
amine metabolic process GO:0009308 38 0.025
positive regulation of cell communication GO:0010647 271 0.024
nucleoside metabolic process GO:0009116 179 0.024
regulation of nervous system development GO:0051960 264 0.024
catabolic process GO:0009056 351 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
cellular macromolecule localization GO:0070727 122 0.024
regulation of ion transport GO:0043269 245 0.023
Rat
positive regulation of developmental process GO:0051094 283 0.023
sexual reproduction GO:0019953 148 0.023
sex differentiation GO:0007548 113 0.023
Worm
adult locomotory behavior GO:0008344 4 0.023
negative regulation of multicellular organismal process GO:0051241 203 0.023
Worm
reproductive process GO:0022414 372 0.022
Worm
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.022
secretion GO:0046903 307 0.022
response to oxidative stress GO:0006979 186 0.022
cytoplasmic transport GO:0016482 115 0.022
proteolysis GO:0006508 175 0.022
cellular amine metabolic process GO:0044106 38 0.021
positive regulation of gene expression GO:0010628 244 0.021
secretion by cell GO:0032940 248 0.021
response to decreased oxygen levels GO:0036293 237 0.021
regulation of programmed cell death GO:0043067 341 0.021
regulation of apoptotic process GO:0042981 335 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.020
Rat
embryonic pattern specification GO:0009880 1 0.020
Worm
cell projection morphogenesis GO:0048858 123 0.020
positive regulation of nervous system development GO:0051962 178 0.020
protein complex assembly GO:0006461 263 0.020
organonitrogen compound catabolic process GO:1901565 179 0.020
protein phosphorylation GO:0006468 345 0.020
response to inorganic substance GO:0010035 377 0.020
negative regulation of biosynthetic process GO:0009890 168 0.020
Rat
rhythmic process GO:0048511 156 0.019
single organism catabolic process GO:0044712 283 0.019
development of primary sexual characteristics GO:0045137 107 0.019
Worm
response to peptide hormone GO:0043434 278 0.019
positive regulation of transport GO:0051050 245 0.019
nucleoside triphosphate catabolic process GO:0009143 123 0.019
cellular response to endogenous stimulus GO:0071495 377 0.019
locomotion GO:0040011 237 0.019
homeostatic process GO:0042592 331 0.018
response to nutrient levels GO:0031667 370 0.018
establishment of protein localization GO:0045184 141 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
oxoacid metabolic process GO:0043436 290 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
regulation of anatomical structure size GO:0090066 135 0.018
axonogenesis GO:0007409 71 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
positive regulation of phosphate metabolic process GO:0045937 262 0.018
gonad development GO:0008406 104 0.018
Worm
cellular protein localization GO:0034613 122 0.018
cellular response to oxygen containing compound GO:1901701 386 0.017
positive regulation of cell development GO:0010720 176 0.017
learning or memory GO:0007611 90 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
cell adhesion GO:0007155 110 0.017
positive regulation of cellular biosynthetic process GO:0031328 295 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
Rat
male mating behavior GO:0060179 3 0.017
regulation of cell development GO:0060284 263 0.017
reproductive system development GO:0061458 128 0.017
Worm
positive regulation of cellular component organization GO:0051130 200 0.017
cellular response to peptide GO:1901653 133 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
positive regulation of signaling GO:0023056 270 0.016
circadian rhythm GO:0007623 88 0.016
single organism cellular localization GO:1902580 102 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
olfactory learning GO:0008355 1 0.016
growth GO:0040007 165 0.016
feeding behavior GO:0007631 53 0.015
membrane organization GO:0061024 94 0.015
synaptic vesicle endocytosis GO:0048488 4 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
olfactory behavior GO:0042048 2 0.015
neural crest cell development GO:0014032 2 0.015
cell cycle GO:0007049 101 0.015
embryonic axis specification GO:0000578 1 0.015
regulation of catalytic activity GO:0050790 304 0.015
regulation of protein metabolic process GO:0051246 289 0.015
ion transmembrane transport GO:0034220 365 0.015
purine containing compound catabolic process GO:0072523 138 0.015
forebrain development GO:0030900 98 0.015
regulation of cell proliferation GO:0042127 359 0.015
ribonucleotide metabolic process GO:0009259 231 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
regulation of neurogenesis GO:0050767 247 0.014
response to insulin GO:0032868 133 0.014
eye morphogenesis GO:0048592 4 0.014
cellular chemical homeostasis GO:0055082 247 0.014
positive regulation of cell death GO:0010942 184 0.014
multicellular organism reproduction GO:0032504 233 0.014
chemosensory behavior GO:0007635 2 0.014
vesicle mediated transport GO:0016192 181 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
regulation of cell differentiation GO:0045595 320 0.014
cellular ketone metabolic process GO:0042180 51 0.014
intracellular protein transport GO:0006886 79 0.014
organic acid metabolic process GO:0006082 292 0.014
regulation of locomotion GO:0040012 148 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
positive regulation of signal transduction GO:0009967 175 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
Rat
positive regulation of programmed cell death GO:0043068 157 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.013
Rat
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
cell growth GO:0016049 104 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
single organism behavior GO:0044708 130 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
regulation of neuron differentiation GO:0045664 208 0.013
endocytosis GO:0006897 84 0.013
metaphase anaphase transition of cell cycle GO:0044784 1 0.013
chromosome segregation GO:0007059 2 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
Rat
regulation of phosphate metabolic process GO:0019220 349 0.013
heterocycle catabolic process GO:0046700 167 0.013
rhythmic behavior GO:0007622 24 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
metal ion transport GO:0030001 289 0.013
Rat
purine containing compound metabolic process GO:0072521 253 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
response to growth factor GO:0070848 189 0.013
dendrite development GO:0016358 72 0.013
rna localization GO:0006403 4 0.012
organic acid biosynthetic process GO:0016053 83 0.012
cytoskeleton dependent cytokinesis GO:0061640 2 0.012
reproductive structure development GO:0048608 128 0.012
Worm
synapse organization GO:0050808 46 0.012
gamete generation GO:0007276 124 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
motor neuron axon guidance GO:0008045 1 0.012
gliogenesis GO:0042063 93 0.012
regulation of growth GO:0040008 105 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
negative regulation of gene expression GO:0010629 199 0.012
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.012
salivary gland morphogenesis GO:0007435 1 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
regulation of synaptic plasticity GO:0048167 70 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
organophosphate catabolic process GO:0046434 148 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
spindle organization GO:0007051 2 0.012
regulation of neuron projection development GO:0010975 161 0.011
camera type eye morphogenesis GO:0048593 2 0.011
skeletal muscle cell differentiation GO:0035914 2 0.011
cellular amino acid metabolic process GO:0006520 107 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
regulation of kinase activity GO:0043549 117 0.011
negative regulation of monocyte chemotaxis GO:0090027 2 0.011
positive regulation of molecular function GO:0044093 230 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
biological adhesion GO:0022610 110 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
salivary gland development GO:0007431 3 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
respiratory gaseous exchange GO:0007585 4 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
response to peptide GO:1901652 292 0.011
gastrulation GO:0007369 2 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
carbohydrate metabolic process GO:0005975 130 0.011
cardiovascular system development GO:0072358 134 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
regulation of signal transduction GO:0009966 318 0.011
heart morphogenesis GO:0003007 3 0.011
centrosome organization GO:0051297 1 0.011
regulation of neuronal synaptic plasticity GO:0048168 31 0.011
alternative mrna splicing via spliceosome GO:0000380 4 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
response to vitamin GO:0033273 131 0.011
intracellular signal transduction GO:0035556 314 0.011
multi organism reproductive process GO:0044703 262 0.011
regulation of transferase activity GO:0051338 123 0.010
cellular response to peptide hormone stimulus GO:0071375 120 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
male sex differentiation GO:0046661 64 0.010
negative regulation of apoptotic process GO:0043066 181 0.010
locomotor rhythm GO:0045475 1 0.010
carboxylic acid metabolic process GO:0019752 289 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
dicarboxylic acid metabolic process GO:0043648 42 0.010
positive regulation of secretion by cell GO:1903532 128 0.010

Mark1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
epilepsy syndrome DOID:1826 0 0.034
central nervous system disease DOID:331 0 0.034
brain disease DOID:936 0 0.034
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034
urinary system disease DOID:18 0 0.010