Rattus norvegicus

109 known processes

Cacna1d

calcium channel, voltage-dependent, L type, alpha 1D subunit

Cacna1d biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
exocytosis GO:0006887 60 0.234
response to metal ion GO:0010038 253 0.179
behavior GO:0007610 205 0.178
regulation of rna metabolic process GO:0051252 391 0.157
negative regulation of cell proliferation GO:0008285 119 0.151
cell cell signaling GO:0007267 335 0.147
Human Rat
regulation of ion transport GO:0043269 245 0.145
regulation of secretion GO:0051046 224 0.142
response to cytokine GO:0034097 215 0.141
single organism biosynthetic process GO:0044711 342 0.134
comma shaped body morphogenesis GO:0072049 2 0.131
rna metabolic process GO:0016070 406 0.121
g protein coupled receptor signaling pathway GO:0007186 242 0.118
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.118
regulation of molecular function GO:0065009 398 0.107
regulation of secretion by cell GO:1903530 208 0.106
secretion GO:0046903 307 0.104
second messenger mediated signaling GO:0019932 51 0.086
defense response GO:0006952 194 0.086
vesicle mediated transport GO:0016192 181 0.085
inflammatory response GO:0006954 150 0.081
negative regulation of biosynthetic process GO:0009890 168 0.079
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.077
response to inorganic substance GO:0010035 377 0.076
transcription from rna polymerase ii promoter GO:0006366 252 0.075
regulation of rna biosynthetic process GO:2001141 381 0.073
secretion by cell GO:0032940 248 0.068
single organism intracellular transport GO:1902582 166 0.068
regulation of signal transduction GO:0009966 318 0.068
positive regulation of transport GO:0051050 245 0.067
Human
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.066
cellular homeostasis GO:0019725 252 0.065
cation transport GO:0006812 382 0.064
cellular response to hormone stimulus GO:0032870 247 0.064
negative regulation of cellular biosynthetic process GO:0031327 161 0.063
protein complex assembly GO:0006461 263 0.063
divalent inorganic cation homeostasis GO:0072507 165 0.063
nitrogen compound transport GO:0071705 229 0.061
regulation of nucleic acid templated transcription GO:1903506 380 0.061
chemical homeostasis GO:0048878 292 0.060
lipid metabolic process GO:0006629 283 0.060
immune response GO:0006955 104 0.058
response to hexose GO:0009746 144 0.058
organonitrogen compound biosynthetic process GO:1901566 167 0.057
central nervous system development GO:0007417 311 0.054
transmission of nerve impulse GO:0019226 42 0.053
nucleic acid templated transcription GO:0097659 379 0.052
cytosolic calcium ion homeostasis GO:0051480 140 0.052
cellular response to endogenous stimulus GO:0071495 377 0.051
tissue development GO:0009888 252 0.051
calcium ion homeostasis GO:0055074 162 0.050
carbohydrate derivative metabolic process GO:1901135 346 0.050
brain development GO:0007420 247 0.050
macromolecular complex subunit organization GO:0043933 339 0.049
response to extracellular stimulus GO:0009991 380 0.047
intracellular transport GO:0046907 185 0.047
positive regulation of rna biosynthetic process GO:1902680 197 0.045
cellular response to steroid hormone stimulus GO:0071383 93 0.045
rna biosynthetic process GO:0032774 380 0.045
negative regulation of cellular metabolic process GO:0031324 281 0.043
response to monosaccharide GO:0034284 159 0.043
sexual reproduction GO:0019953 148 0.043
developmental process involved in reproduction GO:0003006 159 0.042
positive regulation of secretion GO:0051047 140 0.042
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.042
neurological system process GO:0050877 219 0.041
hormone metabolic process GO:0042445 69 0.041
negative regulation of gene expression GO:0010629 199 0.040
positive regulation of secretion by cell GO:1903532 128 0.040
cellular amino acid metabolic process GO:0006520 107 0.040
response to external biotic stimulus GO:0043207 221 0.040
biological adhesion GO:0022610 110 0.040
response to decreased oxygen levels GO:0036293 237 0.040
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.040
response to glucocorticoid GO:0051384 223 0.039
macromolecular complex assembly GO:0065003 273 0.039
regulation of vesicle mediated transport GO:0060627 81 0.039
anion transport GO:0006820 178 0.038
response to oxygen levels GO:0070482 265 0.038
programmed cell death GO:0012501 392 0.038
positive regulation of rna metabolic process GO:0051254 203 0.037
response to peptide GO:1901652 292 0.037
cellular hormone metabolic process GO:0034754 49 0.037
cellular component biogenesis GO:0044085 368 0.037
protein complex biogenesis GO:0070271 263 0.036
positive regulation of gene expression GO:0010628 244 0.036
response to radiation GO:0009314 137 0.035
blood circulation GO:0008015 183 0.035
Human
positive regulation of cellular biosynthetic process GO:0031328 295 0.035
intracellular signal transduction GO:0035556 314 0.034
ion homeostasis GO:0050801 212 0.034
response to nutrient levels GO:0031667 370 0.034
positive regulation of biosynthetic process GO:0009891 319 0.034
head development GO:0060322 247 0.034
cellular response to glucocorticoid stimulus GO:0071385 68 0.034
positive regulation of phosphate metabolic process GO:0045937 262 0.034
negative regulation of metabolic process GO:0009892 331 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.033
response to starvation GO:0042594 59 0.033
response to corticosteroid GO:0031960 235 0.032
divalent metal ion transport GO:0070838 132 0.032
circulatory system process GO:0003013 183 0.032
Human
cellular response to peptide hormone stimulus GO:0071375 120 0.032
regulation of apoptotic process GO:0042981 335 0.031
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.031
regulation of amine transport GO:0051952 54 0.031
l glutamate import GO:0051938 2 0.031
response to fatty acid GO:0070542 65 0.030
single organism reproductive process GO:0044702 297 0.030
gamete generation GO:0007276 124 0.030
transcription dna templated GO:0006351 377 0.030
cellular chemical homeostasis GO:0055082 247 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
cellular response to organic cyclic compound GO:0071407 202 0.029
regulation of transcription dna templated GO:0006355 374 0.028
cellular amine metabolic process GO:0044106 38 0.028
alcohol metabolic process GO:0006066 77 0.028
nucleotide metabolic process GO:0009117 279 0.028
amide transport GO:0042886 105 0.028
regulation of cellular component organization GO:0051128 368 0.028
urogenital system development GO:0001655 78 0.027
negative regulation of signaling GO:0023057 157 0.027
apoptotic process GO:0006915 381 0.027
protein complex subunit organization GO:0071822 302 0.027
multicellular organismal reproductive process GO:0048609 233 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
multicellular organismal signaling GO:0035637 44 0.027
Human
negative regulation of rna metabolic process GO:0051253 123 0.027
cellular response to stress GO:0033554 269 0.027
regulation of lyase activity GO:0051339 22 0.027
homeostatic process GO:0042592 331 0.026
calcium ion import GO:0070509 22 0.026
multi organism reproductive process GO:0044703 262 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.026
cellular response to peptide GO:1901653 133 0.026
regulation of programmed cell death GO:0043067 341 0.026
nucleoside phosphate biosynthetic process GO:1901293 102 0.026
motor neuron axon guidance GO:0008045 1 0.025
regeneration GO:0031099 163 0.025
response to peptide hormone GO:0043434 278 0.025
negative regulation of camp biosynthetic process GO:0030818 12 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
metal ion homeostasis GO:0055065 186 0.025
adult locomotory behavior GO:0008344 4 0.024
positive regulation of transcription dna templated GO:0045893 197 0.024
carbohydrate derivative biosynthetic process GO:1901137 124 0.024
positive regulation of nucleic acid templated transcription GO:1903508 197 0.024
regulation of cell proliferation GO:0042127 359 0.024
negative regulation of rna biosynthetic process GO:1902679 118 0.024
regulation of hormone levels GO:0010817 187 0.024
purine nucleotide metabolic process GO:0006163 229 0.024
circulatory system development GO:0072359 134 0.023
cellular response to organonitrogen compound GO:0071417 197 0.023
regulation of phosphate metabolic process GO:0019220 349 0.023
response to glucose GO:0009749 136 0.023
carbohydrate homeostasis GO:0033500 75 0.023
response to transition metal nanoparticle GO:1990267 122 0.023
regulation of catalytic activity GO:0050790 304 0.023
regulation of hormone secretion GO:0046883 106 0.023
regulation of exocytosis GO:0017157 37 0.023
response to other organism GO:0051707 220 0.022
organic acid biosynthetic process GO:0016053 83 0.022
regulation of system process GO:0044057 208 0.022
Human
positive regulation of developmental process GO:0051094 283 0.022
cellular ion homeostasis GO:0006873 184 0.022
multicellular organism reproduction GO:0032504 233 0.022
cation transmembrane transport GO:0098655 263 0.021
cell adhesion GO:0007155 110 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
cellular response to lipid GO:0071396 201 0.021
response to camp GO:0051591 91 0.021
ribonucleotide biosynthetic process GO:0009260 85 0.021
catabolic process GO:0009056 351 0.021
regulation of cellular localization GO:0060341 263 0.021
cellular response to oxygen containing compound GO:1901701 386 0.021
cellular component assembly GO:0022607 360 0.021
positive regulation of signaling GO:0023056 270 0.021
regulation of protein transport GO:0051223 68 0.021
response to interleukin 1 GO:0070555 55 0.021
glucose homeostasis GO:0042593 75 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
reproductive process GO:0022414 372 0.020
lipid biosynthetic process GO:0008610 128 0.020
single organism catabolic process GO:0044712 283 0.020
calcium ion transport GO:0006816 131 0.020
negative regulation of apoptotic process GO:0043066 181 0.020
metanephric comma shaped body morphogenesis GO:0072278 2 0.020
negative regulation of transcription dna templated GO:0045892 116 0.019
positive regulation of neurogenesis GO:0050769 165 0.019
purine nucleotide biosynthetic process GO:0006164 83 0.019
oxoacid metabolic process GO:0043436 290 0.019
positive regulation of cell development GO:0010720 176 0.019
cellular cation homeostasis GO:0030003 180 0.019
organic acid metabolic process GO:0006082 292 0.019
divalent inorganic cation transport GO:0072511 134 0.019
single organism carbohydrate metabolic process GO:0044723 118 0.019
cytoskeleton organization GO:0007010 111 0.018
response to alkaloid GO:0043279 132 0.018
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
synaptic transmission GO:0007268 235 0.018
Rat
metanephric part of ureteric bud development GO:0035502 1 0.018
cellular modified amino acid metabolic process GO:0006575 61 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
cell projection organization GO:0030030 302 0.018
small molecule biosynthetic process GO:0044283 124 0.018
epithelial cell differentiation GO:0030855 71 0.018
endocrine system development GO:0035270 30 0.017
olfactory behavior GO:0042048 2 0.017
negative regulation of nucleic acid templated transcription GO:1903507 117 0.017
axis specification GO:0009798 4 0.017
sex differentiation GO:0007548 113 0.017
heart contraction GO:0060047 57 0.017
Human
response to biotic stimulus GO:0009607 226 0.017
positive regulation of peptide hormone secretion GO:0090277 50 0.017
transmembrane transport GO:0055085 412 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
purine containing compound biosynthetic process GO:0072522 85 0.017
protein oligomerization GO:0051259 191 0.016
cytoplasmic transport GO:0016482 115 0.016
hormone transport GO:0009914 121 0.016
carboxylic acid transport GO:0046942 115 0.016
response to carbohydrate GO:0009743 183 0.016
response to molecule of bacterial origin GO:0002237 194 0.016
negative regulation of cell communication GO:0010648 158 0.016
purine containing compound metabolic process GO:0072521 253 0.016
spermatogenesis GO:0007283 99 0.016
immune system process GO:0002376 204 0.016
positive regulation of glutamate secretion GO:0014049 8 0.016
response to ketone GO:1901654 182 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
regulation of blood pressure GO:0008217 83 0.016
s shaped body morphogenesis GO:0072050 2 0.016
metanephric s shaped body morphogenesis GO:0072284 2 0.016
regulation of defense response GO:0031347 68 0.015
cellular ketone metabolic process GO:0042180 51 0.015
cyclic nucleotide biosynthetic process GO:0009190 63 0.015
regulation of metal ion transport GO:0010959 118 0.015
response to purine containing compound GO:0014074 126 0.015
cell type specific apoptotic process GO:0097285 134 0.015
regulation of immune system process GO:0002682 123 0.015
response to calcium ion GO:0051592 59 0.015
positive regulation of amine transport GO:0051954 26 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
forebrain development GO:0030900 98 0.014
regulation of mapk cascade GO:0043408 116 0.014
regulation of chronic inflammatory response GO:0002676 3 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
carboxylic acid metabolic process GO:0019752 289 0.014
cation homeostasis GO:0055080 195 0.014
regulation of peptide secretion GO:0002791 82 0.014
regulation of phosphorus metabolic process GO:0051174 349 0.014
male gamete generation GO:0048232 99 0.014
sulfur compound metabolic process GO:0006790 70 0.014
regulation of adenylate cyclase activity GO:0045761 18 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
sensory perception of pain GO:0019233 73 0.013
Rat
negative regulation of lyase activity GO:0051350 8 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
renal system development GO:0072001 67 0.013
negative regulation of gamma aminobutyric acid secretion GO:0014053 3 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
response to nutrient GO:0007584 248 0.013
regulation of anion transport GO:0044070 43 0.013
acute inflammatory response GO:0002526 58 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
response to lipopolysaccharide GO:0032496 191 0.013
negative regulation of cyclic nucleotide metabolic process GO:0030800 15 0.013
cellular response to hexose stimulus GO:0071331 65 0.013
purine ribonucleotide biosynthetic process GO:0009152 81 0.013
protein transport GO:0015031 132 0.013
reproduction GO:0000003 245 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
macromolecule localization GO:0033036 252 0.013
camp biosynthetic process GO:0006171 47 0.013
positive regulation of molecular function GO:0044093 230 0.012
organophosphate metabolic process GO:0019637 370 0.012
kidney development GO:0001822 67 0.012
cellular response to corticosteroid stimulus GO:0071384 69 0.012
cell chemotaxis GO:0060326 31 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
negative regulation of intracellular estrogen receptor signaling pathway GO:0033147 2 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
organic anion transport GO:0015711 132 0.012
regulation of protein modification process GO:0031399 194 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
amino acid transport GO:0006865 70 0.012
locomotor rhythm GO:0045475 1 0.012
regulation of response to stress GO:0080134 126 0.012
cerebellar purkinje cell layer development GO:0021680 2 0.012
steroid metabolic process GO:0008202 73 0.012
peptide hormone secretion GO:0030072 84 0.012
negative regulation of camp metabolic process GO:0030815 14 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.012
response to hypoxia GO:0001666 231 0.012
hormone secretion GO:0046879 115 0.012
vascular process in circulatory system GO:0003018 96 0.012
potassium ion transmembrane transport GO:0071805 71 0.011
negative regulation of nucleotide metabolic process GO:0045980 23 0.011
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.011
response to fibroblast growth factor GO:0071774 29 0.011
response to testosterone GO:0033574 55 0.011
hepaticobiliary system development GO:0061008 90 0.011
embryonic pattern specification GO:0009880 1 0.011
cardiovascular system development GO:0072358 134 0.011
negative regulation of innate immune response GO:0045824 4 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
calcium mediated signaling GO:0019722 23 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
organic substance catabolic process GO:1901575 316 0.011
cell growth GO:0016049 104 0.011
regulation of organelle organization GO:0033043 80 0.011
response to vitamin GO:0033273 131 0.011
signal release GO:0023061 145 0.011
cerebellar cortex formation GO:0021697 2 0.011
hematopoietic progenitor cell differentiation GO:0002244 2 0.011
protein phosphorylation GO:0006468 345 0.011
cellular response to metal ion GO:0071248 55 0.011
cell motility GO:0048870 202 0.011
cyclic purine nucleotide metabolic process GO:0052652 62 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
positive regulation of cell death GO:0010942 184 0.010
cellular response to monosaccharide stimulus GO:0071326 67 0.010
cellular response to alcohol GO:0097306 87 0.010
regulation of heart contraction GO:0008016 48 0.010
Human
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
proteolysis GO:0006508 175 0.010
negative regulation of purine nucleotide biosynthetic process GO:1900372 12 0.010
peptide transport GO:0015833 97 0.010
cytokine production GO:0001816 61 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
intestinal absorption GO:0050892 3 0.010
organelle organization GO:0006996 266 0.010
cellular calcium ion homeostasis GO:0006874 160 0.010
monocarboxylic acid transport GO:0015718 52 0.010
response to blue light GO:0009637 1 0.010
cellular carbohydrate metabolic process GO:0044262 72 0.010
locomotion GO:0040011 237 0.010
regulation of defecation GO:2000292 1 0.010

Cacna1d disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.016