Rattus norvegicus

0 known processes

Pkib

protein kinase (cAMP-dependent, catalytic) inhibitor beta

(Aliases: RATPKINH,Prkacn2,PKINH)

Pkib biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
anatomical structure morphogenesis GO:0009653 298 0.110
cellular response to oxygen containing compound GO:1901701 386 0.104
regulation of transcription dna templated GO:0006355 374 0.078
rna biosynthetic process GO:0032774 380 0.074
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.070
response to inorganic substance GO:0010035 377 0.069
cellular homeostasis GO:0019725 252 0.066
transcription dna templated GO:0006351 377 0.065
reproductive process GO:0022414 372 0.063
cellular response to endogenous stimulus GO:0071495 377 0.063
response to nutrient GO:0007584 248 0.062
positive regulation of multicellular organismal process GO:0051240 387 0.061
regulation of molecular function GO:0065009 398 0.061
cell cell signaling GO:0007267 335 0.061
positive regulation of cellular biosynthetic process GO:0031328 295 0.060
apoptotic process GO:0006915 381 0.059
response to extracellular stimulus GO:0009991 380 0.057
amine metabolic process GO:0009308 38 0.056
response to corticosteroid GO:0031960 235 0.056
positive regulation of cell death GO:0010942 184 0.056
circulatory system process GO:0003013 183 0.056
cellular component assembly GO:0022607 360 0.055
neurological system process GO:0050877 219 0.055
response to metal ion GO:0010038 253 0.053
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.052
reproduction GO:0000003 245 0.051
localization of cell GO:0051674 202 0.051
regulation of phosphorus metabolic process GO:0051174 349 0.051
cellular chemical homeostasis GO:0055082 247 0.051
organic acid metabolic process GO:0006082 292 0.050
cellular amino acid metabolic process GO:0006520 107 0.050
regulation of cell differentiation GO:0045595 320 0.050
positive regulation of biosynthetic process GO:0009891 319 0.048
response to cytokine GO:0034097 215 0.048
carboxylic acid metabolic process GO:0019752 289 0.048
regulation of nervous system development GO:0051960 264 0.047
neuron projection development GO:0031175 273 0.047
regulation of signal transduction GO:0009966 318 0.047
rna metabolic process GO:0016070 406 0.047
positive regulation of neuron migration GO:2001224 2 0.047
response to decreased oxygen levels GO:0036293 237 0.045
cellular ketone metabolic process GO:0042180 51 0.045
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.045
programmed cell death GO:0012501 392 0.044
intracellular signal transduction GO:0035556 314 0.043
response to monosaccharide GO:0034284 159 0.043
response to nutrient levels GO:0031667 370 0.043
cell projection organization GO:0030030 302 0.043
learning or memory GO:0007611 90 0.042
neuron development GO:0048666 286 0.042
cellular response to hormone stimulus GO:0032870 247 0.042
response to glucocorticoid GO:0051384 223 0.042
macromolecule localization GO:0033036 252 0.041
central nervous system development GO:0007417 311 0.041
cellular component movement GO:0006928 248 0.041
cellular amine metabolic process GO:0044106 38 0.040
regulation of cellular amine metabolic process GO:0033238 8 0.040
regulation of cellular ketone metabolic process GO:0010565 27 0.040
neuron projection morphogenesis GO:0048812 122 0.039
locomotion GO:0040011 237 0.039
response to molecule of bacterial origin GO:0002237 194 0.039
regulation of cellular amino acid metabolic process GO:0006521 2 0.038
single organism reproductive process GO:0044702 297 0.038
cellular response to organic cyclic compound GO:0071407 202 0.038
regulation of multicellular organismal development GO:2000026 376 0.037
divalent metal ion transport GO:0070838 132 0.037
lipid metabolic process GO:0006629 283 0.037
cellular response to stress GO:0033554 269 0.037
regulation of programmed cell death GO:0043067 341 0.036
regulation of cell proliferation GO:0042127 359 0.036
response to lipopolysaccharide GO:0032496 191 0.036
cell projection morphogenesis GO:0048858 123 0.036
behavior GO:0007610 205 0.036
response to growth factor GO:0070848 189 0.036
cell motility GO:0048870 202 0.036
response to hypoxia GO:0001666 231 0.035
negative regulation of multicellular organismal process GO:0051241 203 0.035
protein localization GO:0008104 191 0.035
negative regulation of gene expression GO:0010629 199 0.035
positive regulation of locomotion GO:0040017 102 0.035
cellular response to external stimulus GO:0071496 118 0.035
response to wounding GO:0009611 254 0.035
regulation of rna metabolic process GO:0051252 391 0.035
head development GO:0060322 247 0.034
response to bacterium GO:0009617 200 0.034
cellular response to growth factor stimulus GO:0071363 162 0.034
nucleic acid templated transcription GO:0097659 379 0.034
positive regulation of response to stimulus GO:0048584 285 0.034
transmembrane transport GO:0055085 412 0.034
cellular component morphogenesis GO:0032989 155 0.033
regulation of intracellular signal transduction GO:1902531 218 0.033
positive regulation of phosphate metabolic process GO:0045937 262 0.033
cellular component biogenesis GO:0044085 368 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.033
response to ketone GO:1901654 182 0.033
negative regulation of metabolic process GO:0009892 331 0.033
multi organism reproductive process GO:0044703 262 0.033
regulation of cell development GO:0060284 263 0.033
regulation of phosphorylation GO:0042325 248 0.032
response to carbohydrate GO:0009743 183 0.032
regulation of neurogenesis GO:0050767 247 0.032
cation transport GO:0006812 382 0.032
positive regulation of cell motility GO:2000147 97 0.032
cellular response to organonitrogen compound GO:0071417 197 0.032
response to peptide hormone GO:0043434 278 0.031
regulation of protein metabolic process GO:0051246 289 0.031
carbohydrate derivative metabolic process GO:1901135 346 0.031
oxoacid metabolic process GO:0043436 290 0.031
positive regulation of developmental process GO:0051094 283 0.031
anion transport GO:0006820 178 0.031
regulation of nucleic acid templated transcription GO:1903506 380 0.031
aging GO:0007568 241 0.031
dephosphorylation GO:0016311 98 0.030
cellular response to peptide hormone stimulus GO:0071375 120 0.030
cell morphogenesis GO:0000902 142 0.030
response to peptide GO:1901652 292 0.030
ion homeostasis GO:0050801 212 0.030
cellular response to lipid GO:0071396 201 0.030
brain development GO:0007420 247 0.029
secretion by cell GO:0032940 248 0.029
regulation of cellular component movement GO:0051270 150 0.029
organophosphate metabolic process GO:0019637 370 0.029
positive regulation of cellular amine metabolic process GO:0033240 3 0.029
regulation of cytokine production GO:0001817 56 0.028
sexual reproduction GO:0019953 148 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.028
response to hexose GO:0009746 144 0.028
axon development GO:0061564 96 0.028
chemical homeostasis GO:0048878 292 0.028
positive regulation of phosphorylation GO:0042327 177 0.028
inflammatory response GO:0006954 150 0.027
neuron differentiation GO:0030182 368 0.027
regulation of apoptotic process GO:0042981 335 0.027
response to other organism GO:0051707 220 0.027
ion transmembrane transport GO:0034220 365 0.027
positive regulation of rna metabolic process GO:0051254 203 0.027
regulation of rna biosynthetic process GO:2001141 381 0.027
cellular lipid metabolic process GO:0044255 208 0.027
regeneration GO:0031099 163 0.027
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.027
positive regulation of cell proliferation GO:0008284 249 0.027
negative regulation of response to stimulus GO:0048585 155 0.027
positive regulation of nervous system development GO:0051962 178 0.026
carbohydrate metabolic process GO:0005975 130 0.026
cell migration GO:0016477 197 0.026
regulation of system process GO:0044057 208 0.026
response to biotic stimulus GO:0009607 226 0.026
regulation of phosphate metabolic process GO:0019220 349 0.026
positive regulation of transcription dna templated GO:0045893 197 0.026
protein complex subunit organization GO:0071822 302 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
regulation of anatomical structure morphogenesis GO:0022603 141 0.025
establishment of protein localization GO:0045184 141 0.025
chemotaxis GO:0006935 66 0.025
homeostatic process GO:0042592 331 0.025
response to vitamin GO:0033273 131 0.025
response to acid chemical GO:0001101 222 0.025
positive regulation of gene expression GO:0010628 244 0.024
positive regulation of cell migration GO:0030335 96 0.024
positive regulation of programmed cell death GO:0043068 157 0.024
positive regulation of apoptotic process GO:0043065 154 0.024
cognition GO:0050890 92 0.024
signal release GO:0023061 145 0.024
regulation of cell motility GO:2000145 131 0.024
muscle system process GO:0003012 115 0.024
single organism biosynthetic process GO:0044711 342 0.024
single organism intracellular transport GO:1902582 166 0.024
negative regulation of cell death GO:0060548 229 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
response to purine containing compound GO:0014074 126 0.024
positive regulation of cell development GO:0010720 176 0.023
secretion GO:0046903 307 0.023
metal ion transport GO:0030001 289 0.023
calcium ion homeostasis GO:0055074 162 0.023
cellular response to insulin stimulus GO:0032869 81 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
regulation of catalytic activity GO:0050790 304 0.023
circulatory system development GO:0072359 134 0.022
cation homeostasis GO:0055080 195 0.022
regulation of protein phosphorylation GO:0001932 183 0.022
blood circulation GO:0008015 183 0.022
cellular response to cytokine stimulus GO:0071345 127 0.022
peptidyl amino acid modification GO:0018193 126 0.022
cellular response to peptide GO:1901653 133 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
response to glucose GO:0009749 136 0.022
cellular response to nitrogen compound GO:1901699 210 0.021
regulation of cell projection organization GO:0031344 175 0.021
response to transition metal nanoparticle GO:1990267 122 0.021
small gtpase mediated signal transduction GO:0007264 36 0.021
response to oxygen levels GO:0070482 265 0.021
cellular catabolic process GO:0044248 295 0.021
cell part morphogenesis GO:0032990 123 0.021
developmental process involved in reproduction GO:0003006 159 0.021
regulation of membrane potential GO:0042391 110 0.021
single organism organelle organization GO:1902589 180 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
neuron death GO:0070997 127 0.020
positive regulation of rna biosynthetic process GO:1902680 197 0.020
protein phosphorylation GO:0006468 345 0.020
single organism cellular localization GO:1902580 102 0.020
neuronal action potential GO:0019228 35 0.020
negative regulation of programmed cell death GO:0043069 183 0.020
hormone transport GO:0009914 121 0.020
regulation of cellular localization GO:0060341 263 0.020
macromolecular complex subunit organization GO:0043933 339 0.020
transmission of nerve impulse GO:0019226 42 0.020
multicellular organism reproduction GO:0032504 233 0.020
regulation of cell migration GO:0030334 128 0.019
inorganic ion transmembrane transport GO:0098660 229 0.019
response to oxidative stress GO:0006979 186 0.019
synaptic growth at neuromuscular junction GO:0051124 1 0.019
immune system process GO:0002376 204 0.019
protein complex assembly GO:0006461 263 0.019
cellular divalent inorganic cation homeostasis GO:0072503 162 0.019
protein oligomerization GO:0051259 191 0.019
macromolecular complex assembly GO:0065003 273 0.019
positive regulation of protein phosphorylation GO:0001934 135 0.019
small molecule biosynthetic process GO:0044283 124 0.019
action potential GO:0001508 54 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
organic acid biosynthetic process GO:0016053 83 0.019
lipid biosynthetic process GO:0008610 128 0.019
positive regulation of transport GO:0051050 245 0.019
response to toxic substance GO:0009636 133 0.019
cellular cation homeostasis GO:0030003 180 0.019
negative regulation of developmental process GO:0051093 125 0.018
vesicle mediated transport GO:0016192 181 0.018
regulation of neuron death GO:1901214 115 0.018
positive regulation of neuron projection development GO:0010976 99 0.018
protein complex biogenesis GO:0070271 263 0.018
anatomical structure formation involved in morphogenesis GO:0048646 83 0.018
wound healing GO:0042060 122 0.018
gamete generation GO:0007276 124 0.018
metal ion homeostasis GO:0055065 186 0.018
cellular response to biotic stimulus GO:0071216 59 0.018
single organism carbohydrate metabolic process GO:0044723 118 0.018
nitrogen compound transport GO:0071705 229 0.018
synaptic transmission GO:0007268 235 0.018
negative regulation of cell differentiation GO:0045596 99 0.018
organelle organization GO:0006996 266 0.018
carboxylic acid biosynthetic process GO:0046394 83 0.018
positive regulation of cell communication GO:0010647 271 0.018
positive regulation of cellular component movement GO:0051272 102 0.018
positive regulation of protein metabolic process GO:0051247 178 0.017
defense response GO:0006952 194 0.017
regulation of immune system process GO:0002682 123 0.017
cellular response to steroid hormone stimulus GO:0071383 93 0.017
peptidyl tyrosine modification GO:0018212 72 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.017
eye morphogenesis GO:0048592 4 0.017
regulation of neuron differentiation GO:0045664 208 0.017
protein transport GO:0015031 132 0.017
signal transduction by phosphorylation GO:0023014 144 0.017
regulation of synaptic transmission GO:0050804 141 0.017
regulation of secretion GO:0051046 224 0.017
regulation of locomotion GO:0040012 148 0.017
intracellular transport GO:0046907 185 0.017
hormone secretion GO:0046879 115 0.017
response to estrogen GO:0043627 232 0.017
response to radiation GO:0009314 137 0.017
cellular metal ion homeostasis GO:0006875 172 0.016
proteolysis GO:0006508 175 0.016
regulation of hormone levels GO:0010817 187 0.016
positive regulation of transcription factor import into nucleus GO:0042993 4 0.016
mapk cascade GO:0000165 140 0.016
nucleotide metabolic process GO:0009117 279 0.016
heterocycle catabolic process GO:0046700 167 0.016
monocarboxylic acid metabolic process GO:0032787 152 0.016
multicellular organismal signaling GO:0035637 44 0.016
regulation of transferase activity GO:0051338 123 0.016
axonogenesis GO:0007409 71 0.016
response to mechanical stimulus GO:0009612 134 0.015
response to external biotic stimulus GO:0043207 221 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
cellular response to reactive oxygen species GO:0034614 55 0.015
regulation of secretion by cell GO:1903530 208 0.015
gliogenesis GO:0042063 93 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
regulation of lipid metabolic process GO:0019216 68 0.015
divalent inorganic cation transport GO:0072511 134 0.015
response to hydrogen peroxide GO:0042542 89 0.015
peptidyl tyrosine phosphorylation GO:0018108 72 0.015
gland development GO:0048732 155 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
tissue development GO:0009888 252 0.015
cardiovascular system development GO:0072358 134 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
catabolic process GO:0009056 351 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
negative regulation of transport GO:0051051 136 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.015
urogenital system development GO:0001655 78 0.015
regulation of ion transport GO:0043269 245 0.015
negative regulation of nervous system development GO:0051961 79 0.014
negative regulation of cell development GO:0010721 82 0.014
regulation of cell morphogenesis GO:0022604 77 0.014
protein dephosphorylation GO:0006470 38 0.014
positive regulation of isotype switching to igg isotypes GO:0048304 1 0.014
female pregnancy GO:0007565 122 0.014
regulation of neuron projection development GO:0010975 161 0.014
cell type specific apoptotic process GO:0097285 134 0.014
cellular response to glucocorticoid stimulus GO:0071385 68 0.014
salivary gland morphogenesis GO:0007435 1 0.014
cellular response to ketone GO:1901655 51 0.014
regulation of homeostatic process GO:0032844 101 0.014
endocytosis GO:0006897 84 0.014
reproductive structure development GO:0048608 128 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
response to estradiol GO:0032355 164 0.014
peptide transport GO:0015833 97 0.014
salivary gland development GO:0007431 3 0.014
positive regulation of mapk cascade GO:0043410 92 0.014
regulation of neural precursor cell proliferation GO:2000177 16 0.014
epithelium development GO:0060429 96 0.014
spermatogenesis GO:0007283 99 0.014
forebrain development GO:0030900 98 0.014
positive regulation of signaling GO:0023056 270 0.014
response to mineralocorticoid GO:0051385 49 0.014
cytoplasmic transport GO:0016482 115 0.014
gastrulation GO:0007369 2 0.014
male gamete generation GO:0048232 99 0.013
purine containing compound metabolic process GO:0072521 253 0.013
ras protein signal transduction GO:0007265 29 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
response to insulin GO:0032868 133 0.013
negative regulation of signaling GO:0023057 157 0.013
coenzyme metabolic process GO:0006732 86 0.013
positive regulation of molecular function GO:0044093 230 0.013
negative regulation of cell communication GO:0010648 158 0.013
dna metabolic process GO:0006259 96 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
growth GO:0040007 165 0.013
amide transport GO:0042886 105 0.013
regulation of protein modification process GO:0031399 194 0.013
organophosphate catabolic process GO:0046434 148 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
cation transmembrane transport GO:0098655 263 0.013
rhythmic process GO:0048511 156 0.013
regulation of cellular component organization GO:0051128 368 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
cell substrate adhesion GO:0031589 29 0.013
organic acid transport GO:0015849 116 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
calcium ion transport GO:0006816 131 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
response to temperature stimulus GO:0009266 94 0.012
positive regulation of cytokine production GO:0001819 42 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
cellular response to abiotic stimulus GO:0071214 85 0.012
motor neuron axon guidance GO:0008045 1 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
response to light stimulus GO:0009416 52 0.012
response to electrical stimulus GO:0051602 56 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
cellular ion homeostasis GO:0006873 184 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
protein homooligomerization GO:0051260 91 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
regulation of kinase activity GO:0043549 117 0.011
multicellular organism growth GO:0035264 1 0.011
cell adhesion GO:0007155 110 0.011
regulation of cell adhesion GO:0030155 52 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
response to alkaloid GO:0043279 132 0.011
establishment of protein localization to organelle GO:0072594 44 0.011
regulation of cell cycle GO:0051726 73 0.011
cellular response to hexose stimulus GO:0071331 65 0.011
reproductive system development GO:0061458 128 0.011
response to amino acid GO:0043200 75 0.011
cellular response to oxidative stress GO:0034599 76 0.011
organic anion transport GO:0015711 132 0.011
lymphocyte migration GO:0072676 3 0.011
taxis GO:0042330 67 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
cellular response to alcohol GO:0097306 87 0.011
muscle contraction GO:0006936 88 0.011
regulation of metal ion transport GO:0010959 118 0.011
multi multicellular organism process GO:0044706 138 0.011
protein targeting GO:0006605 61 0.011
response to fatty acid GO:0070542 65 0.011
sex differentiation GO:0007548 113 0.011
glial cell differentiation GO:0010001 65 0.011
blood vessel development GO:0001568 69 0.011
liver development GO:0001889 90 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
cytokine production GO:0001816 61 0.011
single organism behavior GO:0044708 130 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
cellular response to lipopolysaccharide GO:0071222 55 0.011
cell activation GO:0001775 97 0.011
sensory perception GO:0007600 101 0.011
regulation of hydrolase activity GO:0051336 143 0.011
cellular macromolecule localization GO:0070727 122 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
positive regulation of isotype switching GO:0045830 1 0.010
organic substance catabolic process GO:1901575 316 0.010
cellular carbohydrate metabolic process GO:0044262 72 0.010
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.010
positive regulation of cellular protein metabolic process GO:0032270 167 0.010
positive regulation of transferase activity GO:0051347 81 0.010
response to reactive oxygen species GO:0000302 120 0.010
neuron apoptotic process GO:0051402 88 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
organ regeneration GO:0031100 101 0.010
monosaccharide metabolic process GO:0005996 61 0.010
biological adhesion GO:0022610 110 0.010
ensheathment of neurons GO:0007272 40 0.010
enzyme linked receptor protein signaling pathway GO:0007167 116 0.010
hepaticobiliary system development GO:0061008 90 0.010
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
lipid storage GO:0019915 1 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010

Pkib disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012