Rattus norvegicus

0 known processes

Wnt6

wingless-type MMTV integration site family, member 6

Wnt6 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to metal ion GO:0010038 253 0.190
regulation of apoptotic process GO:0042981 335 0.139
organic acid metabolic process GO:0006082 292 0.135
macromolecular complex assembly GO:0065003 273 0.133
negative regulation of metabolic process GO:0009892 331 0.130
response to estrogen GO:0043627 232 0.126
Rat
protein complex biogenesis GO:0070271 263 0.118
programmed cell death GO:0012501 392 0.106
regulation of system process GO:0044057 208 0.101
anatomical structure morphogenesis GO:0009653 298 0.089
Human Rat Fly
oxoacid metabolic process GO:0043436 290 0.088
response to hypoxia GO:0001666 231 0.087
apoptotic process GO:0006915 381 0.079
cellular component assembly GO:0022607 360 0.077
positive regulation of synaptic transmission GO:0050806 62 0.072
carboxylic acid metabolic process GO:0019752 289 0.068
negative regulation of programmed cell death GO:0043069 183 0.065
protein complex subunit organization GO:0071822 302 0.063
circulatory system process GO:0003013 183 0.061
macromolecular complex subunit organization GO:0043933 339 0.060
negative regulation of cell death GO:0060548 229 0.058
regulation of protein metabolic process GO:0051246 289 0.057
Rat
s shaped body morphogenesis GO:0072050 2 0.056
organelle organization GO:0006996 266 0.056
negative regulation of apoptotic process GO:0043066 181 0.055
regulation of programmed cell death GO:0043067 341 0.054
cellular response to stress GO:0033554 269 0.054
Rat
response to peptide hormone GO:0043434 278 0.053
Rat
cellular component biogenesis GO:0044085 368 0.052
ion transmembrane transport GO:0034220 365 0.051
protein localization GO:0008104 191 0.048
cellular response to oxygen containing compound GO:1901701 386 0.047
Rat
response to inorganic substance GO:0010035 377 0.047
Rat
response to growth factor GO:0070848 189 0.046
cellular ion homeostasis GO:0006873 184 0.044
macromolecule localization GO:0033036 252 0.043
cellular component movement GO:0006928 248 0.043
organic substance catabolic process GO:1901575 316 0.041
transmembrane transport GO:0055085 412 0.040
catabolic process GO:0009056 351 0.040
response to decreased oxygen levels GO:0036293 237 0.039
regulation of nucleic acid templated transcription GO:1903506 380 0.038
cellular response to peptide GO:1901653 133 0.038
Rat
tissue development GO:0009888 252 0.038
Human Rat
organ morphogenesis GO:0009887 75 0.037
Human Rat Fly
carbohydrate derivative metabolic process GO:1901135 346 0.036
single organism organelle organization GO:1902589 180 0.036
neuron projection morphogenesis GO:0048812 122 0.035
Rat
response to oxygen levels GO:0070482 265 0.035
Rat
regulation of cellular localization GO:0060341 263 0.035
transcription from rna polymerase ii promoter GO:0006366 252 0.034
regulation of catalytic activity GO:0050790 304 0.034
Rat
protein oligomerization GO:0051259 191 0.034
male sex differentiation GO:0046661 64 0.034
regulation of molecular function GO:0065009 398 0.034
Rat
skeletal system development GO:0001501 41 0.033
regulation of cellular ketone metabolic process GO:0010565 27 0.033
negative regulation of cell communication GO:0010648 158 0.033
neuron projection development GO:0031175 273 0.032
Rat
cell type specific apoptotic process GO:0097285 134 0.032
negative regulation of gene expression GO:0010629 199 0.032
homeostatic process GO:0042592 331 0.032
renal system development GO:0072001 67 0.031
regulation of rna metabolic process GO:0051252 391 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.031
heart morphogenesis GO:0003007 3 0.031
regulation of cellular protein metabolic process GO:0032268 267 0.031
Rat
ribonucleotide metabolic process GO:0009259 231 0.030
positive regulation of cell death GO:0010942 184 0.030
development of primary sexual characteristics GO:0045137 107 0.030
positive regulation of cellular component movement GO:0051272 102 0.029
nucleic acid templated transcription GO:0097659 379 0.029
cellular component morphogenesis GO:0032989 155 0.029
Rat
urogenital system development GO:0001655 78 0.028
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.028
sex differentiation GO:0007548 113 0.028
chemical homeostasis GO:0048878 292 0.028
positive regulation of cellular biosynthetic process GO:0031328 295 0.028
reproduction GO:0000003 245 0.028
intestinal absorption GO:0050892 3 0.028
protein phosphorylation GO:0006468 345 0.028
Rat
cellular macromolecule localization GO:0070727 122 0.027
cellular response to growth factor stimulus GO:0071363 162 0.027
blood circulation GO:0008015 183 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
cellular protein localization GO:0034613 122 0.027
gamete generation GO:0007276 124 0.027
cellular amino acid metabolic process GO:0006520 107 0.027
nucleoside metabolic process GO:0009116 179 0.027
positive regulation of cell communication GO:0010647 271 0.027
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
neuron differentiation GO:0030182 368 0.025
Rat
transcription dna templated GO:0006351 377 0.025
multicellular organism reproduction GO:0032504 233 0.025
cellular response to organonitrogen compound GO:0071417 197 0.024
Rat
positive regulation of signaling GO:0023056 270 0.024
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.024
kidney development GO:0001822 67 0.024
purine ribonucleotide metabolic process GO:0009150 227 0.024
protein transport GO:0015031 132 0.024
enzyme linked receptor protein signaling pathway GO:0007167 116 0.024
anterior posterior pattern specification GO:0009952 1 0.024
comma shaped body morphogenesis GO:0072049 2 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
Rat
regulation of membrane potential GO:0042391 110 0.024
response to transition metal nanoparticle GO:1990267 122 0.024
response to biotic stimulus GO:0009607 226 0.024
cellular response to metal ion GO:0071248 55 0.024
protein complex assembly GO:0006461 263 0.023
action potential GO:0001508 54 0.023
regulation of transcription dna templated GO:0006355 374 0.023
developmental process involved in reproduction GO:0003006 159 0.023
Rat
positive regulation of nervous system development GO:0051962 178 0.023
gland development GO:0048732 155 0.023
Rat
cellular calcium ion homeostasis GO:0006874 160 0.023
cell morphogenesis involved in differentiation GO:0000904 119 0.023
regulation of rna biosynthetic process GO:2001141 381 0.023
positive regulation of cell differentiation GO:0045597 217 0.023
cellular amine metabolic process GO:0044106 38 0.023
regulation of anatomical structure size GO:0090066 135 0.022
Rat Fly
regulation of phosphorus metabolic process GO:0051174 349 0.022
Rat
ureteric bud development GO:0001657 14 0.022
mesonephric tubule development GO:0072164 14 0.022
regulation of blood circulation GO:1903522 110 0.022
purine containing compound metabolic process GO:0072521 253 0.022
negative regulation of cell proliferation GO:0008285 119 0.021
positive regulation of protein modification process GO:0031401 142 0.021
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.021
regulation of cell migration GO:0030334 128 0.021
positive regulation of developmental process GO:0051094 283 0.021
Human
brain development GO:0007420 247 0.021
embryonic skeletal system morphogenesis GO:0048704 3 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
amine metabolic process GO:0009308 38 0.020
potassium ion transport GO:0006813 97 0.020
positive regulation of cell projection organization GO:0031346 111 0.020
ossification GO:0001503 70 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
response to peptide GO:1901652 292 0.020
Rat
ion homeostasis GO:0050801 212 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
intracellular transport GO:0046907 185 0.020
rna metabolic process GO:0016070 406 0.020
tissue regeneration GO:0042246 36 0.020
regulation of cellular component organization GO:0051128 368 0.020
protein targeting GO:0006605 61 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
regulation of phosphate metabolic process GO:0019220 349 0.019
Rat
cellular amide metabolic process GO:0043603 44 0.019
cellular response to lipid GO:0071396 201 0.019
Rat
organophosphate metabolic process GO:0019637 370 0.019
regulation of hormone levels GO:0010817 187 0.019
reproductive process GO:0022414 372 0.019
Rat
positive regulation of cellular component organization GO:0051130 200 0.019
cell cycle GO:0007049 101 0.018
cell morphogenesis GO:0000902 142 0.018
Rat
embryonic skeletal system development GO:0048706 3 0.018
regulation of homeostatic process GO:0032844 101 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
regeneration GO:0031099 163 0.018
Rat
aromatic compound catabolic process GO:0019439 168 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
neuron apoptotic process GO:0051402 88 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
Rat
cell projection organization GO:0030030 302 0.018
Rat
glycosyl compound metabolic process GO:1901657 182 0.018
response to nutrient GO:0007584 248 0.018
cellular chemical homeostasis GO:0055082 247 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
sexual reproduction GO:0019953 148 0.017
positive regulation of programmed cell death GO:0043068 157 0.017
rhythmic process GO:0048511 156 0.017
carbohydrate metabolic process GO:0005975 130 0.017
cellular cation homeostasis GO:0030003 180 0.017
cytoskeleton organization GO:0007010 111 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
response to nutrient levels GO:0031667 370 0.017
Rat
mesonephros development GO:0001823 14 0.017
cellular response to peptide hormone stimulus GO:0071375 120 0.017
Rat
intracellular signal transduction GO:0035556 314 0.017
Rat
cellular catabolic process GO:0044248 295 0.016
hematopoietic progenitor cell differentiation GO:0002244 2 0.016
wound healing GO:0042060 122 0.016
Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
negative regulation of transport GO:0051051 136 0.016
response to glucocorticoid GO:0051384 223 0.016
Rat
regulation of cellular response to stress GO:0080135 49 0.016
Rat
ribonucleoside metabolic process GO:0009119 174 0.016
establishment of protein localization GO:0045184 141 0.016
cellular response to endogenous stimulus GO:0071495 377 0.016
Rat
purine ribonucleoside metabolic process GO:0046128 168 0.016
cellular ketone metabolic process GO:0042180 51 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
Rat
cation transport GO:0006812 382 0.016
male gonad development GO:0008584 59 0.015
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.015
nuclear transport GO:0051169 49 0.015
metal ion homeostasis GO:0055065 186 0.015
regulation of protein transport GO:0051223 68 0.015
response to wounding GO:0009611 254 0.015
Rat
heterocycle catabolic process GO:0046700 167 0.015
positive regulation of molecular function GO:0044093 230 0.015
Rat
regulation of body fluid levels GO:0050878 90 0.015
multi organism reproductive process GO:0044703 262 0.015
striated muscle tissue development GO:0014706 58 0.015
cell cell signaling GO:0007267 335 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
purine containing compound catabolic process GO:0072523 138 0.015
muscle organ development GO:0007517 50 0.014
axis specification GO:0009798 4 0.014
axonogenesis GO:0007409 71 0.014
membrane organization GO:0061024 94 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
Rat
rna biosynthetic process GO:0032774 380 0.014
inorganic cation transmembrane transport GO:0098662 202 0.014
proteolysis GO:0006508 175 0.014
nucleocytoplasmic transport GO:0006913 48 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
reproductive structure development GO:0048608 128 0.014
Rat
locomotion GO:0040011 237 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
purine nucleoside triphosphate catabolic process GO:0009146 122 0.014
glycosyl compound catabolic process GO:1901658 126 0.014
regulation of muscle system process GO:0090257 79 0.014
protein heterooligomerization GO:0051291 89 0.014
response to acid chemical GO:0001101 222 0.013
Rat
response to vitamin GO:0033273 131 0.013
activation of cysteine type endopeptidase activity GO:0097202 4 0.013
spermatogenesis GO:0007283 99 0.013
nephron morphogenesis GO:0072028 13 0.013
response to reactive oxygen species GO:0000302 120 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
Rat
cytoplasmic transport GO:0016482 115 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 10 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
muscle system process GO:0003012 115 0.013
response to alkaloid GO:0043279 132 0.013
bmp signaling pathway GO:0030509 4 0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.013
positive regulation of multicellular organismal process GO:0051240 387 0.013
Human
response to extracellular stimulus GO:0009991 380 0.013
Rat
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
fertilization GO:0009566 3 0.013
regulation of signal transduction GO:0009966 318 0.013
Rat
skeletal muscle tissue development GO:0007519 31 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
response to estradiol GO:0032355 164 0.013
Rat
response to oxidative stress GO:0006979 186 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
macromolecule catabolic process GO:0009057 58 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
Rat
kidney morphogenesis GO:0060993 13 0.012
regulation of cell cycle GO:0051726 73 0.012
neuron development GO:0048666 286 0.012
Rat
regulation of phosphorylation GO:0042325 248 0.012
Rat
anion transport GO:0006820 178 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
regulation of establishment of protein localization GO:0070201 69 0.012
muscle tissue development GO:0060537 58 0.012
development of primary male sexual characteristics GO:0046546 59 0.012
multicellular organism growth GO:0035264 1 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
regulation of protein localization GO:0032880 81 0.012
cell motility GO:0048870 202 0.012
aging GO:0007568 241 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
cellular homeostasis GO:0019725 252 0.012
response to toxic substance GO:0009636 133 0.012
cation transmembrane transport GO:0098655 263 0.012
regulation of cellular component movement GO:0051270 150 0.012
sensory organ development GO:0007423 74 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
regulation of organ formation GO:0003156 2 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
protein localization to organelle GO:0033365 57 0.012
single organism membrane organization GO:0044802 74 0.012
dephosphorylation GO:0016311 98 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
response to carbohydrate GO:0009743 183 0.011
female sex differentiation GO:0046660 59 0.011
erythrocyte differentiation GO:0030218 1 0.011
metal ion transport GO:0030001 289 0.011
regulation of locomotion GO:0040012 148 0.011
regulation of cell projection organization GO:0031344 175 0.011
secretion by cell GO:0032940 248 0.011
response to other organism GO:0051707 220 0.011
positive regulation of signal transduction GO:0009967 175 0.011
Rat
salivary gland development GO:0007431 3 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
single organism biosynthetic process GO:0044711 342 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
cellular protein complex assembly GO:0043623 44 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
maintenance of location GO:0051235 17 0.011
cellular response to inorganic substance GO:0071241 65 0.011
sequestering of calcium ion GO:0051208 8 0.011
metanephric s shaped body morphogenesis GO:0072284 2 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
Rat
positive regulation of cell development GO:0010720 176 0.011
response to corticosteroid GO:0031960 235 0.011
Rat
regulation of neuron apoptotic process GO:0043523 83 0.011
regulation of multicellular organismal development GO:2000026 376 0.011
Human Rat
peptide metabolic process GO:0006518 32 0.011
cellular modified amino acid metabolic process GO:0006575 61 0.011
nitrogen compound transport GO:0071705 229 0.011
regulation of cell differentiation GO:0045595 320 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
negative regulation of cellular metabolic process GO:0031324 281 0.011
single organism reproductive process GO:0044702 297 0.011
Rat
single organism intracellular transport GO:1902582 166 0.011
endomembrane system organization GO:0010256 48 0.011
positive regulation of secretion GO:0051047 140 0.010
hormone transport GO:0009914 121 0.010
nucleotide metabolic process GO:0009117 279 0.010
response to insulin GO:0032868 133 0.010
regulation of stem cell differentiation GO:2000736 2 0.010
muscle structure development GO:0061061 87 0.010
response to hexose GO:0009746 144 0.010
male gamete generation GO:0048232 99 0.010
positive regulation of blood circulation GO:1903524 65 0.010
monocarboxylic acid biosynthetic process GO:0072330 48 0.010
regulation of hydrolase activity GO:0051336 143 0.010

Wnt6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
musculoskeletal system disease DOID:17 0 0.020
bone disease DOID:0080001 0 0.011
connective tissue disease DOID:65 0 0.011