Rattus norvegicus

37 known processes

Wnt4

wingless-type MMTV integration site family, member 4

(Aliases: MGC112773)

Wnt4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.070
Human
regulation of rna metabolic process GO:0051252 391 0.068
Human
transcription dna templated GO:0006351 377 0.067
Human
gland development GO:0048732 155 0.066
Human Rat
regulation of rna biosynthetic process GO:2001141 381 0.062
Human
regulation of phosphate metabolic process GO:0019220 349 0.062
Rat
nucleic acid templated transcription GO:0097659 379 0.060
Human
carboxylic acid metabolic process GO:0019752 289 0.057
intracellular signal transduction GO:0035556 314 0.055
Rat
rna biosynthetic process GO:0032774 380 0.054
Human
response to inorganic substance GO:0010035 377 0.054
nucleobase containing small molecule metabolic process GO:0055086 316 0.052
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.051
Human
regulation of cellular protein metabolic process GO:0032268 267 0.050
Rat
organic acid metabolic process GO:0006082 292 0.050
regulation of signal transduction GO:0009966 318 0.050
Human Rat
protein phosphorylation GO:0006468 345 0.048
Rat
oxoacid metabolic process GO:0043436 290 0.047
positive regulation of biosynthetic process GO:0009891 319 0.047
Human
regulation of molecular function GO:0065009 398 0.047
Rat
single organism biosynthetic process GO:0044711 342 0.046
Human
cellular response to endogenous stimulus GO:0071495 377 0.046
cell projection organization GO:0030030 302 0.046
Rat
organophosphate metabolic process GO:0019637 370 0.045
negative regulation of macromolecule metabolic process GO:0010605 260 0.045
Human
response to glucocorticoid GO:0051384 223 0.045
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.044
cellular amino acid metabolic process GO:0006520 107 0.043
positive regulation of rna biosynthetic process GO:1902680 197 0.043
Human
regulation of intracellular signal transduction GO:1902531 218 0.042
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.042
Human
positive regulation of phosphate metabolic process GO:0045937 262 0.042
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.041
Human
positive regulation of response to stimulus GO:0048584 285 0.040
Human Rat
positive regulation of cell proliferation GO:0008284 249 0.040
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.039
organic substance catabolic process GO:1901575 316 0.038
negative regulation of cell proliferation GO:0008285 119 0.038
regulation of phosphorus metabolic process GO:0051174 349 0.038
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.037
Rat
regulation of catalytic activity GO:0050790 304 0.037
Rat
response to decreased oxygen levels GO:0036293 237 0.036
regulation of cell proliferation GO:0042127 359 0.036
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.036
regulation of phosphorylation GO:0042325 248 0.035
Rat
programmed cell death GO:0012501 392 0.035
negative regulation of cellular metabolic process GO:0031324 281 0.034
Human
cellular component assembly GO:0022607 360 0.034
rna metabolic process GO:0016070 406 0.034
Human
cellular ketone metabolic process GO:0042180 51 0.034
Human
negative regulation of metabolic process GO:0009892 331 0.034
Human
catabolic process GO:0009056 351 0.034
amine metabolic process GO:0009308 38 0.034
regulation of protein modification process GO:0031399 194 0.033
Rat
central nervous system development GO:0007417 311 0.033
carbohydrate derivative metabolic process GO:1901135 346 0.033
cellular component biogenesis GO:0044085 368 0.032
single organism catabolic process GO:0044712 283 0.032
apoptotic process GO:0006915 381 0.032
mapk cascade GO:0000165 140 0.032
Rat
cellular response to stress GO:0033554 269 0.032
regulation of cellular ketone metabolic process GO:0010565 27 0.032
Human
response to nutrient levels GO:0031667 370 0.031
Rat
nucleotide metabolic process GO:0009117 279 0.031
transcription from rna polymerase ii promoter GO:0006366 252 0.031
protein complex subunit organization GO:0071822 302 0.031
regulation of response to stress GO:0080134 126 0.031
Rat
response to wounding GO:0009611 254 0.031
Rat
regulation of programmed cell death GO:0043067 341 0.030
positive regulation of programmed cell death GO:0043068 157 0.030
regulation of multicellular organismal development GO:2000026 376 0.030
Human Rat
positive regulation of molecular function GO:0044093 230 0.030
Rat
response to metal ion GO:0010038 253 0.030
cellular amine metabolic process GO:0044106 38 0.029
response to oxygen levels GO:0070482 265 0.029
Rat
cellular component movement GO:0006928 248 0.029
purine nucleotide metabolic process GO:0006163 229 0.029
regulation of transcription dna templated GO:0006355 374 0.028
Human
protein complex assembly GO:0006461 263 0.028
response to growth factor GO:0070848 189 0.028
Human
response to peptide GO:1901652 292 0.028
Rat
positive regulation of gene expression GO:0010628 244 0.028
Human
positive regulation of cellular component organization GO:0051130 200 0.028
ribose phosphate metabolic process GO:0019693 235 0.027
cellular response to oxygen containing compound GO:1901701 386 0.027
response to extracellular stimulus GO:0009991 380 0.027
Rat
defense response GO:0006952 194 0.027
macromolecular complex subunit organization GO:0043933 339 0.027
positive regulation of catalytic activity GO:0043085 184 0.027
Rat
regulation of mapk cascade GO:0043408 116 0.027
Rat
regulation of protein metabolic process GO:0051246 289 0.026
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.026
Human
neuron projection development GO:0031175 273 0.026
Rat
negative regulation of signaling GO:0023057 157 0.026
Human
response to carbohydrate GO:0009743 183 0.026
protein complex biogenesis GO:0070271 263 0.026
cellular catabolic process GO:0044248 295 0.026
response to glucose GO:0009749 136 0.026
aging GO:0007568 241 0.026
response to corticosteroid GO:0031960 235 0.025
Rat
cellular response to organonitrogen compound GO:0071417 197 0.025
Rat
cellular protein localization GO:0034613 122 0.025
Human
neuron differentiation GO:0030182 368 0.025
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.025
Human
ion homeostasis GO:0050801 212 0.025
negative regulation of biosynthetic process GO:0009890 168 0.025
Human
chemical homeostasis GO:0048878 292 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
positive regulation of multicellular organismal process GO:0051240 387 0.025
Human
regulation of cellular amine metabolic process GO:0033238 8 0.025
positive regulation of developmental process GO:0051094 283 0.024
Human
purine containing compound metabolic process GO:0072521 253 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.024
Human
secretion GO:0046903 307 0.024
cellular response to growth factor stimulus GO:0071363 162 0.024
Human
regulation of cellular component movement GO:0051270 150 0.024
glycosyl compound metabolic process GO:1901657 182 0.024
positive regulation of rna metabolic process GO:0051254 203 0.023
Human
cellular response to nitrogen compound GO:1901699 210 0.023
Rat
purine ribonucleotide metabolic process GO:0009150 227 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
Human
regulation of apoptotic process GO:0042981 335 0.023
regulation of cellular component organization GO:0051128 368 0.023
protein oligomerization GO:0051259 191 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.023
response to monosaccharide GO:0034284 159 0.022
negative regulation of gene expression GO:0010629 199 0.022
Human
positive regulation of cell death GO:0010942 184 0.022
immune system process GO:0002376 204 0.022
negative regulation of transport GO:0051051 136 0.022
lipid metabolic process GO:0006629 283 0.022
Human
multi organism reproductive process GO:0044703 262 0.021
brain development GO:0007420 247 0.021
reproductive process GO:0022414 372 0.021
Human Rat
tissue development GO:0009888 252 0.021
Human Rat
homeostatic process GO:0042592 331 0.021
oxidation reduction process GO:0055114 304 0.021
negative regulation of multicellular organismal process GO:0051241 203 0.021
Human
organonitrogen compound catabolic process GO:1901565 179 0.021
nucleoside triphosphate metabolic process GO:0009141 144 0.021
cation transport GO:0006812 382 0.021
response to other organism GO:0051707 220 0.021
regulation of protein kinase activity GO:0045859 105 0.021
Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
regulation of membrane potential GO:0042391 110 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
Rat
response to nutrient GO:0007584 248 0.020
regulation of system process GO:0044057 208 0.020
response to hexose GO:0009746 144 0.020
regulation of cellular response to stress GO:0080135 49 0.020
Rat
carbohydrate derivative catabolic process GO:1901136 147 0.019
macromolecular complex assembly GO:0065003 273 0.019
positive regulation of apoptotic process GO:0043065 154 0.019
cellular homeostasis GO:0019725 252 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
Human
ion transmembrane transport GO:0034220 365 0.019
single organism reproductive process GO:0044702 297 0.019
Human Rat
positive regulation of signaling GO:0023056 270 0.019
Human Rat
protein transport GO:0015031 132 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
Rat
response to hypoxia GO:0001666 231 0.019
ribonucleotide metabolic process GO:0009259 231 0.018
response to peptide hormone GO:0043434 278 0.018
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
peptidyl amino acid modification GO:0018193 126 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
response to acid chemical GO:0001101 222 0.018
positive regulation of protein phosphorylation GO:0001934 135 0.018
Rat
localization of cell GO:0051674 202 0.018
ras protein signal transduction GO:0007265 29 0.018
signal transduction by phosphorylation GO:0023014 144 0.018
Rat
cellular nitrogen compound catabolic process GO:0044270 163 0.018
multicellular organism reproduction GO:0032504 233 0.018
organelle organization GO:0006996 266 0.018
enzyme linked receptor protein signaling pathway GO:0007167 116 0.017
head development GO:0060322 247 0.017
macromolecule localization GO:0033036 252 0.017
Human
locomotion GO:0040011 237 0.017
growth GO:0040007 165 0.017
small molecule biosynthetic process GO:0044283 124 0.017
Human
positive regulation of transport GO:0051050 245 0.017
regulation of kinase activity GO:0043549 117 0.017
Rat
transmembrane transport GO:0055085 412 0.017
regulation of transferase activity GO:0051338 123 0.017
Rat
cell motility GO:0048870 202 0.017
nitrogen compound transport GO:0071705 229 0.017
positive regulation of protein modification process GO:0031401 142 0.017
Rat
regulation of anatomical structure size GO:0090066 135 0.017
Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
Human
cellular chemical homeostasis GO:0055082 247 0.017
regulation of cell differentiation GO:0045595 320 0.017
Human
establishment of protein localization GO:0045184 141 0.017
Human
monocarboxylic acid metabolic process GO:0032787 152 0.017
positive regulation of cell differentiation GO:0045597 217 0.016
Human
positive regulation of protein metabolic process GO:0051247 178 0.016
Rat
single organism carbohydrate metabolic process GO:0044723 118 0.016
organophosphate catabolic process GO:0046434 148 0.016
organic acid biosynthetic process GO:0016053 83 0.016
regulation of purine nucleotide metabolic process GO:1900542 115 0.016
circulatory system process GO:0003013 183 0.016
response to lipopolysaccharide GO:0032496 191 0.016
reproduction GO:0000003 245 0.016
positive regulation of transferase activity GO:0051347 81 0.016
Rat
response to estradiol GO:0032355 164 0.016
cell migration GO:0016477 197 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
Rat
regulation of nucleotide metabolic process GO:0006140 117 0.016
immune response GO:0006955 104 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.016
protein localization GO:0008104 191 0.016
Human
response to ketone GO:1901654 182 0.016
Rat
anatomical structure morphogenesis GO:0009653 298 0.016
Human Rat
ribonucleoside metabolic process GO:0009119 174 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
negative regulation of rna metabolic process GO:0051253 123 0.016
Human
regulation of cell development GO:0060284 263 0.016
single organism organelle organization GO:1902589 180 0.016
cation homeostasis GO:0055080 195 0.016
multicellular organism growth GO:0035264 1 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
positive regulation of cell communication GO:0010647 271 0.015
Human Rat
purine ribonucleoside metabolic process GO:0046128 168 0.015
negative regulation of cell communication GO:0010648 158 0.015
Human
response to estrogen GO:0043627 232 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
regulation of cell motility GO:2000145 131 0.015
aromatic compound catabolic process GO:0019439 168 0.015
cellular lipid metabolic process GO:0044255 208 0.015
positive regulation of signal transduction GO:0009967 175 0.015
Human Rat
carboxylic acid biosynthetic process GO:0046394 83 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
response to cytokine GO:0034097 215 0.015
response to transition metal nanoparticle GO:1990267 122 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
purine containing compound catabolic process GO:0072523 138 0.015
cardiovascular system development GO:0072358 134 0.015
Human
ribonucleotide catabolic process GO:0009261 136 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
blood circulation GO:0008015 183 0.014
single organism intracellular transport GO:1902582 166 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
Human
g protein coupled receptor signaling pathway GO:0007186 242 0.014
nucleoside metabolic process GO:0009116 179 0.014
regulation of catabolic process GO:0009894 113 0.014
neuron development GO:0048666 286 0.014
Rat
cell cell signaling GO:0007267 335 0.014
lipid biosynthetic process GO:0008610 128 0.014
Human
salivary gland development GO:0007431 3 0.014
negative regulation of cell death GO:0060548 229 0.014
regulation of ion transport GO:0043269 245 0.014
metal ion homeostasis GO:0055065 186 0.014
calcium ion homeostasis GO:0055074 162 0.014
dna metabolic process GO:0006259 96 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
Human
carbohydrate metabolic process GO:0005975 130 0.014
regulation of cell migration GO:0030334 128 0.014
cellular cation homeostasis GO:0030003 180 0.014
cyclic nucleotide metabolic process GO:0009187 80 0.013
negative regulation of phosphorus metabolic process GO:0010563 80 0.013
response to biotic stimulus GO:0009607 226 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
intracellular transport GO:0046907 185 0.013
regulation of proteasomal protein catabolic process GO:0061136 4 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
response to oxidative stress GO:0006979 186 0.013
response to radiation GO:0009314 137 0.013
positive regulation of cellular component movement GO:0051272 102 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
Human
sexual reproduction GO:0019953 148 0.013
neuronal action potential GO:0019228 35 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.013
regulation of hydrolase activity GO:0051336 143 0.013
response to bacterium GO:0009617 200 0.013
response to external biotic stimulus GO:0043207 221 0.013
cell morphogenesis GO:0000902 142 0.013
Human Rat
heart morphogenesis GO:0003007 3 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
Rat
nucleobase containing compound catabolic process GO:0034655 152 0.013
reproductive structure development GO:0048608 128 0.013
Human Rat
cell part morphogenesis GO:0032990 123 0.013
Rat
developmental process involved in reproduction GO:0003006 159 0.013
Human Rat
tube development GO:0035295 89 0.013
Human Rat
cell growth GO:0016049 104 0.013
positive regulation of cell development GO:0010720 176 0.013
metal ion transport GO:0030001 289 0.013
secretion by cell GO:0032940 248 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
Human
response to organophosphorus GO:0046683 102 0.013
embryonic skeletal system development GO:0048706 3 0.013
regulation of organelle organization GO:0033043 80 0.013
nucleotide catabolic process GO:0009166 139 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
Human Rat
glycosyl compound catabolic process GO:1901658 126 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
heterocycle catabolic process GO:0046700 167 0.012
reproductive system development GO:0061458 128 0.012
Human Rat
regulation of hormone levels GO:0010817 187 0.012
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
gastrulation GO:0007369 2 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
cytoplasmic transport GO:0016482 115 0.012
regeneration GO:0031099 163 0.012
Rat
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
neurological system process GO:0050877 219 0.012
gamete generation GO:0007276 124 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
regulation of nervous system development GO:0051960 264 0.012
muscle cell proliferation GO:0033002 84 0.012
multi multicellular organism process GO:0044706 138 0.012
response to reactive oxygen species GO:0000302 120 0.012
regulation of neurogenesis GO:0050767 247 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
Human
sensory organ development GO:0007423 74 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
regulation of fat cell differentiation GO:0045598 3 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
response to ethanol GO:0045471 162 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.011
Rat
nucleoside catabolic process GO:0009164 126 0.011
peptide transport GO:0015833 97 0.011
behavior GO:0007610 205 0.011
proteolysis GO:0006508 175 0.011
negative regulation of secretion GO:0051048 82 0.011
positive regulation of catabolic process GO:0009896 78 0.011
anion transport GO:0006820 178 0.011
regulation of cell projection organization GO:0031344 175 0.011
synaptic transmission GO:0007268 235 0.011
response to camp GO:0051591 91 0.011
rhythmic process GO:0048511 156 0.011
regulation of secretion by cell GO:1903530 208 0.011
amide transport GO:0042886 105 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
response to toxic substance GO:0009636 133 0.011
forebrain development GO:0030900 98 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
muscle structure development GO:0061061 87 0.011
regulation of protein transport GO:0051223 68 0.011
divalent inorganic cation transport GO:0072511 134 0.011
regulation of secretion GO:0051046 224 0.011
regulation of cytokine production GO:0001817 56 0.011
monosaccharide metabolic process GO:0005996 61 0.011
negative regulation of molecular function GO:0044092 133 0.011
cellular macromolecule localization GO:0070727 122 0.011
Human
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
wound healing GO:0042060 122 0.011
Rat
female pregnancy GO:0007565 122 0.011
calcium ion transport GO:0006816 131 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
establishment of planar polarity GO:0001736 1 0.011
Rat
single organism cellular localization GO:1902580 102 0.011
Human
regulation of neuron death GO:1901214 115 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
circadian rhythm GO:0007623 88 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
cation transmembrane transport GO:0098655 263 0.011
regulation of establishment of planar polarity GO:0090175 2 0.011
Rat
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
regulation of cellular localization GO:0060341 263 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
regulation of blood circulation GO:1903522 110 0.011
peptidyl tyrosine modification GO:0018212 72 0.010
carboxylic acid transport GO:0046942 115 0.010
eye morphogenesis GO:0048592 4 0.010
cellular response to peptide GO:1901653 133 0.010
Rat
stress activated protein kinase signaling cascade GO:0031098 37 0.010
Rat
insulin like growth factor receptor signaling pathway GO:0048009 3 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
divalent metal ion transport GO:0070838 132 0.010
regulation of muscle system process GO:0090257 79 0.010
cell cycle checkpoint GO:0000075 2 0.010
establishment of tissue polarity GO:0007164 2 0.010
Rat
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.010
single organism behavior GO:0044708 130 0.010
action potential GO:0001508 54 0.010
purine containing compound biosynthetic process GO:0072522 85 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
actin filament based process GO:0030029 86 0.010

Wnt4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.013
sensory system disease DOID:0050155 0 0.012
musculoskeletal system disease DOID:17 0 0.011
central nervous system disease DOID:331 0 0.010