Rattus norvegicus

106 known processes

Sod2

superoxide dismutase 2, mitochondrial

Sod2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to inorganic substance GO:0010035 377 0.208
single organism biosynthetic process GO:0044711 342 0.202
homeostatic process GO:0042592 331 0.190
response to molecule of bacterial origin GO:0002237 194 0.180
cellular response to stress GO:0033554 269 0.163
cellular response to reactive oxygen species GO:0034614 55 0.151
neuron death GO:0070997 127 0.149
defense response GO:0006952 194 0.120
response to cadmium ion GO:0046686 35 0.116
cellular response to oxidative stress GO:0034599 76 0.113
response to extracellular stimulus GO:0009991 380 0.109
inflammatory response GO:0006954 150 0.087
carboxylic acid metabolic process GO:0019752 289 0.076
oxoacid metabolic process GO:0043436 290 0.072
response to estrogen GO:0043627 232 0.072
apoptotic process GO:0006915 381 0.069
negative regulation of neuron death GO:1901215 69 0.069
response to wounding GO:0009611 254 0.069
macromolecular complex assembly GO:0065003 273 0.068
response to lipopolysaccharide GO:0032496 191 0.067
response to decreased oxygen levels GO:0036293 237 0.066
positive regulation of transport GO:0051050 245 0.065
aging GO:0007568 241 0.065
regulation of neuron death GO:1901214 115 0.062
reactive oxygen species metabolic process GO:0072593 37 0.062
dicarboxylic acid metabolic process GO:0043648 42 0.062
proteolysis GO:0006508 175 0.058
response to heat GO:0009408 60 0.057
circulatory system process GO:0003013 183 0.057
negative regulation of metabolic process GO:0009892 331 0.055
response to peptide hormone GO:0043434 278 0.054
negative regulation of apoptotic process GO:0043066 181 0.051
single organism organelle organization GO:1902589 180 0.049
hydrogen peroxide metabolic process GO:0042743 13 0.049
cellular lipid metabolic process GO:0044255 208 0.049
nitrogen compound transport GO:0071705 229 0.047
response to purine containing compound GO:0014074 126 0.047
leukocyte migration GO:0050900 38 0.046
lipid metabolic process GO:0006629 283 0.045
regulation of cell motility GO:2000145 131 0.044
response to toxic substance GO:0009636 133 0.043
acyl coa biosynthetic process GO:0071616 7 0.043
establishment of neuroblast polarity GO:0045200 1 0.042
cellular catabolic process GO:0044248 295 0.042
regulation of cell proliferation GO:0042127 359 0.041
positive regulation of cell migration GO:0030335 96 0.041
monocarboxylic acid metabolic process GO:0032787 152 0.040
blood circulation GO:0008015 183 0.040
gastrulation GO:0007369 2 0.039
negative regulation of cellular protein metabolic process GO:0032269 106 0.039
regulation of anatomical structure morphogenesis GO:0022603 141 0.038
response to hypoxia GO:0001666 231 0.038
regulation of response to external stimulus GO:0032101 106 0.038
regulation of response to wounding GO:1903034 69 0.038
cellular amine metabolic process GO:0044106 38 0.037
negative regulation of cell death GO:0060548 229 0.037
protein transport GO:0015031 132 0.037
protein refolding GO:0042026 3 0.037
positive regulation of cellular component movement GO:0051272 102 0.037
negative regulation of cellular metabolic process GO:0031324 281 0.036
regulation of apoptotic process GO:0042981 335 0.035
protein complex biogenesis GO:0070271 263 0.034
regulation of protein metabolic process GO:0051246 289 0.034
response to bacterium GO:0009617 200 0.034
organic acid metabolic process GO:0006082 292 0.034
catabolic process GO:0009056 351 0.034
response to oxidative stress GO:0006979 186 0.034
organic hydroxy compound metabolic process GO:1901615 115 0.034
response to interleukin 1 GO:0070555 55 0.033
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
small molecule biosynthetic process GO:0044283 124 0.033
multicellular organismal homeostasis GO:0048871 49 0.032
positive regulation of multicellular organismal process GO:0051240 387 0.032
cell type specific apoptotic process GO:0097285 134 0.032
neuron apoptotic process GO:0051402 88 0.032
organelle organization GO:0006996 266 0.032
positive regulation of cell proliferation GO:0008284 249 0.031
positive regulation of cell motility GO:2000147 97 0.031
negative regulation of protein metabolic process GO:0051248 114 0.031
positive regulation of secretion GO:0051047 140 0.030
protein oligomerization GO:0051259 191 0.030
protein phosphorylation GO:0006468 345 0.030
negative regulation of programmed cell death GO:0043069 183 0.030
positive regulation of cellular component organization GO:0051130 200 0.030
positive regulation of locomotion GO:0040017 102 0.030
response to metal ion GO:0010038 253 0.030
positive regulation of cellular amine metabolic process GO:0033240 3 0.029
cellular response to molecule of bacterial origin GO:0071219 56 0.029
regulation of secretion GO:0051046 224 0.029
positive regulation of mapk cascade GO:0043410 92 0.029
regulation of cell projection organization GO:0031344 175 0.029
endomembrane system organization GO:0010256 48 0.028
response to oxygen levels GO:0070482 265 0.028
stress activated mapk cascade GO:0051403 35 0.028
wound healing GO:0042060 122 0.028
jnk cascade GO:0007254 28 0.028
organic anion transport GO:0015711 132 0.027
positive regulation of immune system process GO:0002684 90 0.027
positive regulation of cell differentiation GO:0045597 217 0.027
response to peptide GO:1901652 292 0.027
regulation of ion transport GO:0043269 245 0.027
female pregnancy GO:0007565 122 0.027
cellular response to endogenous stimulus GO:0071495 377 0.026
regulation of programmed cell death GO:0043067 341 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.026
cellular amino acid metabolic process GO:0006520 107 0.026
regulation of protein transport GO:0051223 68 0.026
secretion GO:0046903 307 0.025
cellular response to nitrogen compound GO:1901699 210 0.025
response to monosaccharide GO:0034284 159 0.025
cell chemotaxis GO:0060326 31 0.025
signal transduction by phosphorylation GO:0023014 144 0.025
positive regulation of protein metabolic process GO:0051247 178 0.025
cell projection organization GO:0030030 302 0.024
regulation of tube size GO:0035150 89 0.024
organic acid transport GO:0015849 116 0.024
dna metabolic process GO:0006259 96 0.024
response to external biotic stimulus GO:0043207 221 0.023
cellular response to organic cyclic compound GO:0071407 202 0.023
glucose homeostasis GO:0042593 75 0.023
cation transport GO:0006812 382 0.023
response to estradiol GO:0032355 164 0.023
single organism reproductive process GO:0044702 297 0.023
negative regulation of molecular function GO:0044092 133 0.023
cellular response to lipopolysaccharide GO:0071222 55 0.022
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
protein localization GO:0008104 191 0.022
cell redox homeostasis GO:0045454 1 0.021
response to nutrient levels GO:0031667 370 0.021
reactive oxygen species biosynthetic process GO:1903409 8 0.021
response to hexose GO:0009746 144 0.021
reactive nitrogen species metabolic process GO:2001057 1 0.021
cellular homeostasis GO:0019725 252 0.021
cell cell signaling GO:0007267 335 0.021
cellular response to interleukin 1 GO:0071347 37 0.021
response to other organism GO:0051707 220 0.020
chemical homeostasis GO:0048878 292 0.020
cellular ketone metabolic process GO:0042180 51 0.020
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.020
regulation of locomotion GO:0040012 148 0.020
cellular response to alcohol GO:0097306 87 0.020
sensory perception of pain GO:0019233 73 0.020
response to vitamin GO:0033273 131 0.020
response to carbohydrate GO:0009743 183 0.019
cell migration GO:0016477 197 0.019
positive regulation of molecular function GO:0044093 230 0.019
amine metabolic process GO:0009308 38 0.019
carboxylic acid transport GO:0046942 115 0.019
single organism intracellular transport GO:1902582 166 0.019
positive regulation of cell development GO:0010720 176 0.019
nucleotide metabolic process GO:0009117 279 0.019
regulation of molecular function GO:0065009 398 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.018
response to corticosteroid GO:0031960 235 0.018
muscle contraction GO:0006936 88 0.018
negative regulation of reactive oxygen species metabolic process GO:2000378 7 0.018
protein complex subunit organization GO:0071822 302 0.018
response to food GO:0032094 27 0.018
cellular component movement GO:0006928 248 0.018
calcium ion homeostasis GO:0055074 162 0.018
regulation of mapk cascade GO:0043408 116 0.018
regulation of anatomical structure size GO:0090066 135 0.017
organophosphate metabolic process GO:0019637 370 0.017
positive regulation of jnk cascade GO:0046330 13 0.017
regulation of immune system process GO:0002682 123 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
regulation of inflammatory response GO:0050727 48 0.017
antigen receptor mediated signaling pathway GO:0050851 1 0.017
negative regulation of neuron apoptotic process GO:0043524 45 0.017
regulation of blood pressure GO:0008217 83 0.017
response to biotic stimulus GO:0009607 226 0.017
cellular response to extracellular stimulus GO:0031668 73 0.017
regulation of metalloenzyme activity GO:0048552 1 0.016
localization of cell GO:0051674 202 0.016
cation homeostasis GO:0055080 195 0.016
metal ion transport GO:0030001 289 0.016
cellular calcium ion homeostasis GO:0006874 160 0.016
response to antibiotic GO:0046677 39 0.016
macromolecular complex subunit organization GO:0043933 339 0.016
mapk cascade GO:0000165 140 0.016
protein import GO:0017038 37 0.016
regulation of neuron apoptotic process GO:0043523 83 0.016
acetyl coa biosynthetic process from pyruvate GO:0006086 5 0.016
vascular process in circulatory system GO:0003018 96 0.016
neuron development GO:0048666 286 0.016
multi organism reproductive process GO:0044703 262 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
cytoplasmic transport GO:0016482 115 0.016
regulation of phosphate metabolic process GO:0019220 349 0.016
locomotion GO:0040011 237 0.016
response to glucocorticoid GO:0051384 223 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
purine containing compound metabolic process GO:0072521 253 0.015
intracellular transport GO:0046907 185 0.015
regulation of catalytic activity GO:0050790 304 0.015
anion transport GO:0006820 178 0.015
positive regulation of response to external stimulus GO:0032103 51 0.015
fatty acid metabolic process GO:0006631 99 0.015
immune system process GO:0002376 204 0.015
acute inflammatory response GO:0002526 58 0.015
cell cycle GO:0007049 101 0.015
regulation of cell development GO:0060284 263 0.015
submandibular salivary gland formation GO:0060661 1 0.015
regulation of multicellular organismal development GO:2000026 376 0.015
ion homeostasis GO:0050801 212 0.015
cofactor metabolic process GO:0051186 95 0.015
regulation of defense response GO:0031347 68 0.015
macromolecule localization GO:0033036 252 0.015
negative regulation of cell cycle phase transition GO:1901988 4 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
activation of protein kinase activity GO:0032147 47 0.015
organ regeneration GO:0031100 101 0.014
negative regulation of phosphorus metabolic process GO:0010563 80 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
positive regulation of developmental process GO:0051094 283 0.014
neuronal stem cell division GO:0036445 1 0.014
cellular response to biotic stimulus GO:0071216 59 0.014
dephosphorylation GO:0016311 98 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
sensory perception GO:0007600 101 0.014
transcription dna templated GO:0006351 377 0.014
brain development GO:0007420 247 0.014
response to temperature stimulus GO:0009266 94 0.014
positive regulation of nervous system development GO:0051962 178 0.014
response to mechanical stimulus GO:0009612 134 0.014
regulation of phosphorus metabolic process GO:0051174 349 0.014
golgi organization GO:0007030 17 0.014
regulation of protein modification process GO:0031399 194 0.014
cellular amide metabolic process GO:0043603 44 0.014
anatomical structure homeostasis GO:0060249 29 0.013
regulation of hydrogen peroxide biosynthetic process GO:0010728 2 0.013
cellular ion homeostasis GO:0006873 184 0.013
cellular response to glucocorticoid stimulus GO:0071385 68 0.013
mast cell migration GO:0097531 4 0.013
cellular carbohydrate metabolic process GO:0044262 72 0.013
cellular chemical homeostasis GO:0055082 247 0.013
regulation of cell cycle GO:0051726 73 0.013
metal ion homeostasis GO:0055065 186 0.013
negative regulation of oxidoreductase activity GO:0051354 4 0.013
cardiovascular system development GO:0072358 134 0.013
mechanoreceptor differentiation GO:0042490 2 0.013
dna replication GO:0006260 37 0.013
transmembrane transport GO:0055085 412 0.013
nucleocytoplasmic transport GO:0006913 48 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
oxidation reduction process GO:0055114 304 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.013
positive regulation of neuron differentiation GO:0045666 126 0.012
cellular protein localization GO:0034613 122 0.012
cell cycle checkpoint GO:0000075 2 0.012
immune response GO:0006955 104 0.012
regulation of muscle contraction GO:0006937 53 0.012
regulation of nervous system development GO:0051960 264 0.012
multicellular organism growth GO:0035264 1 0.012
regulation of cell differentiation GO:0045595 320 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
regulation of neuron differentiation GO:0045664 208 0.012
acyl coa metabolic process GO:0006637 28 0.012
regulation of lipid metabolic process GO:0019216 68 0.012
response to growth factor GO:0070848 189 0.012
cytokine production GO:0001816 61 0.012
positive regulation of protein modification process GO:0031401 142 0.012
single organism catabolic process GO:0044712 283 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
regulation of reactive oxygen species metabolic process GO:2000377 26 0.012
regulation of jnk cascade GO:0046328 19 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
cellular component biogenesis GO:0044085 368 0.012
cellular modified amino acid metabolic process GO:0006575 61 0.011
regulation of synaptic plasticity GO:0048167 70 0.011
cell fate determination GO:0001709 2 0.011
regulation of phosphorylation GO:0042325 248 0.011
muscle cell proliferation GO:0033002 84 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
behavior GO:0007610 205 0.011
regulation of system process GO:0044057 208 0.011
blood vessel development GO:0001568 69 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
muscle system process GO:0003012 115 0.011
establishment or maintenance of neuroblast polarity GO:0045196 1 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
establishment of protein localization GO:0045184 141 0.011
heart contraction GO:0060047 57 0.011
positive regulation of dna metabolic process GO:0051054 39 0.011
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.011
cellular response to oxygen containing compound GO:1901701 386 0.011
regulation of homeostatic process GO:0032844 101 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
t cell receptor signaling pathway GO:0050852 1 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
negative regulation of protein phosphorylation GO:0001933 44 0.011
cell motility GO:0048870 202 0.011
regulation of secretion by cell GO:1903530 208 0.011
asymmetric stem cell division GO:0098722 2 0.011
interleukin 12 production GO:0032615 3 0.011
organic substance catabolic process GO:1901575 316 0.011
cofactor biosynthetic process GO:0051188 28 0.011
intracellular protein transport GO:0006886 79 0.011
vesicle mediated transport GO:0016192 181 0.011
embryo development GO:0009790 49 0.010
acid secretion GO:0046717 48 0.010
digestive tract development GO:0048565 39 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
mast cell chemotaxis GO:0002551 4 0.010
regulation of cellular component movement GO:0051270 150 0.010
negative regulation of hydrogen peroxide biosynthetic process GO:0010730 2 0.010
regulation of map kinase activity GO:0043405 53 0.010
positive regulation of interferon gamma production GO:0032729 2 0.010
regulation of cell activation GO:0050865 50 0.010
nucleoside phosphate metabolic process GO:0006753 283 0.010
positive regulation of secretion by cell GO:1903532 128 0.010
positive regulation of gene expression GO:0010628 244 0.010
protein targeting GO:0006605 61 0.010
response to insulin GO:0032868 133 0.010
regulation of cytokine biosynthetic process GO:0042035 3 0.010

Sod2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.036
disease of metabolism DOID:0014667 0 0.029
amino acid metabolic disorder DOID:9252 0 0.029
inherited metabolic disorder DOID:655 0 0.029
organic acidemia DOID:0060159 0 0.029
central nervous system disease DOID:331 0 0.015