Rattus norvegicus

0 known processes

Barhl1

BarH-like homeobox 1

(Aliases: Mbh2,Barhl2)

Barhl1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transcription from rna polymerase ii promoter GO:0006366 252 0.395
Mouse Rat Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.261
Mouse Rat Fly
nucleic acid templated transcription GO:0097659 379 0.243
Mouse Rat Fly
transcription dna templated GO:0006351 377 0.207
Mouse Rat Fly
neuron differentiation GO:0030182 368 0.185
Fly
regulation of hormone levels GO:0010817 187 0.185
regulation of transcription dna templated GO:0006355 374 0.185
Mouse Rat Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.183
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.183
Fly
head development GO:0060322 247 0.181
Mouse
response to inorganic substance GO:0010035 377 0.176
rna metabolic process GO:0016070 406 0.174
Mouse Rat Fly
response to bacterium GO:0009617 200 0.161
forebrain development GO:0030900 98 0.155
response to external biotic stimulus GO:0043207 221 0.155
homeostatic process GO:0042592 331 0.154
secretion GO:0046903 307 0.154
cellular calcium ion homeostasis GO:0006874 160 0.141
regulation of rna biosynthetic process GO:2001141 381 0.133
Mouse Rat Fly
single organism reproductive process GO:0044702 297 0.129
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.127
Fly
rna biosynthetic process GO:0032774 380 0.125
Mouse Rat Fly
regulation of multicellular organismal development GO:2000026 376 0.124
negative regulation of cellular biosynthetic process GO:0031327 161 0.122
Fly
negative regulation of gene expression GO:0010629 199 0.118
Fly
brain development GO:0007420 247 0.115
Mouse
response to ketone GO:1901654 182 0.112
positive regulation of developmental process GO:0051094 283 0.108
response to cytokine GO:0034097 215 0.105
intracellular signal transduction GO:0035556 314 0.102
positive regulation of cell communication GO:0010647 271 0.102
cell migration GO:0016477 197 0.101
Mouse
positive regulation of gene expression GO:0010628 244 0.099
Mouse
cytosolic calcium ion homeostasis GO:0051480 140 0.098
regulation of cell differentiation GO:0045595 320 0.097
regulation of nucleic acid templated transcription GO:1903506 380 0.095
Mouse Rat Fly
regulation of neuron differentiation GO:0045664 208 0.092
cation transmembrane transport GO:0098655 263 0.090
response to glucocorticoid GO:0051384 223 0.089
cellular chemical homeostasis GO:0055082 247 0.089
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.088
Fly
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.086
neuron projection development GO:0031175 273 0.085
central nervous system development GO:0007417 311 0.084
Mouse
regulation of rna metabolic process GO:0051252 391 0.084
Mouse Rat Fly
immune system process GO:0002376 204 0.082
regulation of secretion GO:0051046 224 0.078
response to hexose GO:0009746 144 0.077
chemical homeostasis GO:0048878 292 0.077
cellular response to stress GO:0033554 269 0.076
anatomical structure morphogenesis GO:0009653 298 0.076
Fly
small molecule biosynthetic process GO:0044283 124 0.076
positive regulation of signaling GO:0023056 270 0.074
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.074
Mouse
positive regulation of rna metabolic process GO:0051254 203 0.072
Mouse
positive regulation of rna biosynthetic process GO:1902680 197 0.072
Mouse
regulation of nervous system development GO:0051960 264 0.070
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.070
Mouse
hormone transport GO:0009914 121 0.069
multicellular organism reproduction GO:0032504 233 0.068
regulation of cell proliferation GO:0042127 359 0.068
organic hydroxy compound metabolic process GO:1901615 115 0.067
regulation of neurogenesis GO:0050767 247 0.067
response to extracellular stimulus GO:0009991 380 0.067
aging GO:0007568 241 0.066
circulatory system development GO:0072359 134 0.065
programmed cell death GO:0012501 392 0.065
Mouse Worm
regulation of system process GO:0044057 208 0.064
ion transmembrane transport GO:0034220 365 0.063
regulation of secretion by cell GO:1903530 208 0.062
response to toxic substance GO:0009636 133 0.062
negative regulation of rna metabolic process GO:0051253 123 0.062
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.061
Mouse
negative regulation of biosynthetic process GO:0009890 168 0.061
Fly
positive regulation of transcription dna templated GO:0045893 197 0.061
Mouse
regulation of cellular localization GO:0060341 263 0.061
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.060
Fly
negative regulation of macromolecule metabolic process GO:0010605 260 0.060
Fly
response to monosaccharide GO:0034284 159 0.059
nitrogen compound transport GO:0071705 229 0.058
cell projection organization GO:0030030 302 0.057
negative regulation of multicellular organismal process GO:0051241 203 0.057
positive regulation of signal transduction GO:0009967 175 0.055
response to other organism GO:0051707 220 0.054
response to growth factor GO:0070848 189 0.053
regulation of insulin secretion GO:0050796 65 0.052
regulation of peptide hormone secretion GO:0090276 80 0.052
response to glucose GO:0009749 136 0.051
protein complex biogenesis GO:0070271 263 0.051
positive regulation of biosynthetic process GO:0009891 319 0.051
Mouse
protein complex subunit organization GO:0071822 302 0.049
signal transduction by phosphorylation GO:0023014 144 0.049
negative regulation of transport GO:0051051 136 0.049
regulation of cellular component movement GO:0051270 150 0.048
response to carbohydrate GO:0009743 183 0.048
regulation of hormone secretion GO:0046883 106 0.048
cellular component biogenesis GO:0044085 368 0.048
positive regulation of nucleic acid templated transcription GO:1903508 197 0.047
Mouse
regulation of signal transduction GO:0009966 318 0.047
secretion by cell GO:0032940 248 0.047
negative regulation of rna biosynthetic process GO:1902679 118 0.047
Fly
negative regulation of transcription dna templated GO:0045892 116 0.047
Fly
regulation of peptide secretion GO:0002791 82 0.046
response to metal ion GO:0010038 253 0.046
peptide transport GO:0015833 97 0.045
positive regulation of cell proliferation GO:0008284 249 0.045
neuron development GO:0048666 286 0.045
mapk cascade GO:0000165 140 0.045
hormone secretion GO:0046879 115 0.044
divalent inorganic cation transport GO:0072511 134 0.044
cell cell signaling GO:0007267 335 0.043
Fly
macromolecular complex subunit organization GO:0043933 339 0.043
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.043
organic substance catabolic process GO:1901575 316 0.042
regulation of phosphate metabolic process GO:0019220 349 0.042
reproductive process GO:0022414 372 0.042
Worm
regulation of cellular component organization GO:0051128 368 0.041
cellular lipid metabolic process GO:0044255 208 0.040
positive regulation of cell differentiation GO:0045597 217 0.040
g protein coupled receptor signaling pathway GO:0007186 242 0.040
lipid metabolic process GO:0006629 283 0.040
amide transport GO:0042886 105 0.040
calcium ion import GO:0070509 22 0.039
negative regulation of nucleic acid templated transcription GO:1903507 117 0.039
Fly
insulin secretion GO:0030073 69 0.039
multicellular organismal reproductive process GO:0048609 233 0.039
negative regulation of signaling GO:0023057 157 0.038
negative regulation of cellular metabolic process GO:0031324 281 0.038
Fly
cardiovascular system development GO:0072358 134 0.038
regulation of neuron projection development GO:0010975 161 0.038
negative regulation of secretion GO:0051048 82 0.038
response to radiation GO:0009314 137 0.037
positive regulation of multicellular organismal process GO:0051240 387 0.037
carbohydrate derivative metabolic process GO:1901135 346 0.036
response to biotic stimulus GO:0009607 226 0.036
positive regulation of cellular component organization GO:0051130 200 0.036
regulation of cell development GO:0060284 263 0.035
response to corticosteroid GO:0031960 235 0.035
cellular ion homeostasis GO:0006873 184 0.034
regulation of phosphorylation GO:0042325 248 0.034
carbohydrate homeostasis GO:0033500 75 0.034
calcium ion homeostasis GO:0055074 162 0.034
single organism biosynthetic process GO:0044711 342 0.034
response to nutrient levels GO:0031667 370 0.033
cellular metal ion homeostasis GO:0006875 172 0.033
cellular response to cytokine stimulus GO:0071345 127 0.033
signal release GO:0023061 145 0.033
response to estradiol GO:0032355 164 0.033
response to lipopolysaccharide GO:0032496 191 0.033
response to estrogen GO:0043627 232 0.032
regulation of anatomical structure morphogenesis GO:0022603 141 0.032
regulation of programmed cell death GO:0043067 341 0.032
Mouse Worm
response to oxidative stress GO:0006979 186 0.032
transmembrane transport GO:0055085 412 0.032
inorganic ion transmembrane transport GO:0098660 229 0.032
cognition GO:0050890 92 0.031
positive regulation of phosphorus metabolic process GO:0010562 262 0.031
cellular homeostasis GO:0019725 252 0.031
divalent inorganic cation homeostasis GO:0072507 165 0.031
cation transport GO:0006812 382 0.031
muscle system process GO:0003012 115 0.030
cellular component assembly GO:0022607 360 0.030
cellular cation homeostasis GO:0030003 180 0.030
negative regulation of metabolic process GO:0009892 331 0.030
Fly
ion homeostasis GO:0050801 212 0.030
regulation of intracellular signal transduction GO:1902531 218 0.029
angiogenesis GO:0001525 53 0.029
positive regulation of secretion GO:0051047 140 0.029
myeloid leukocyte activation GO:0002274 36 0.029
negative regulation of cell communication GO:0010648 158 0.029
negative regulation of secretion by cell GO:1903531 72 0.029
macromolecular complex assembly GO:0065003 273 0.028
locomotion GO:0040011 237 0.028
Mouse
cellular response to growth factor stimulus GO:0071363 162 0.028
protein complex assembly GO:0006461 263 0.027
cellular carbohydrate metabolic process GO:0044262 72 0.027
neurological system process GO:0050877 219 0.027
Mouse
negative regulation of developmental process GO:0051093 125 0.027
sensory perception GO:0007600 101 0.027
Mouse
positive regulation of cell migration GO:0030335 96 0.027
positive regulation of phosphorylation GO:0042327 177 0.026
regulation of ion transmembrane transport GO:0034765 121 0.026
regulation of apoptotic process GO:0042981 335 0.026
Mouse Worm
gliogenesis GO:0042063 93 0.026
behavior GO:0007610 205 0.026
positive regulation of nervous system development GO:0051962 178 0.026
multicellular organismal signaling GO:0035637 44 0.026
positive regulation of transport GO:0051050 245 0.025
cell motility GO:0048870 202 0.025
Mouse
second messenger mediated signaling GO:0019932 51 0.025
regulation of synaptic transmission GO:0050804 141 0.025
alcohol metabolic process GO:0006066 77 0.025
peptide secretion GO:0002790 86 0.025
cellular amino acid metabolic process GO:0006520 107 0.025
cellular response to endogenous stimulus GO:0071495 377 0.024
hormone metabolic process GO:0042445 69 0.024
negative regulation of cell differentiation GO:0045596 99 0.024
smooth muscle cell proliferation GO:0048659 77 0.024
organophosphate metabolic process GO:0019637 370 0.023
organic acid metabolic process GO:0006082 292 0.023
metal ion homeostasis GO:0055065 186 0.023
response to hypoxia GO:0001666 231 0.023
cellular response to oxidative stress GO:0034599 76 0.023
developmental process involved in reproduction GO:0003006 159 0.023
Worm
response to peptide GO:1901652 292 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.023
localization of cell GO:0051674 202 0.022
Mouse
regulation of peptide transport GO:0090087 87 0.022
cellular response to oxygen containing compound GO:1901701 386 0.022
response to ammonium ion GO:0060359 71 0.022
negative regulation of defecation GO:2000293 1 0.022
response to mechanical stimulus GO:0009612 134 0.022
organonitrogen compound biosynthetic process GO:1901566 167 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
reproduction GO:0000003 245 0.021
cellular component movement GO:0006928 248 0.021
Mouse
memory GO:0007613 54 0.021
reproductive system development GO:0061458 128 0.021
regulation of organelle organization GO:0033043 80 0.021
telencephalon development GO:0021537 62 0.021
development of primary sexual characteristics GO:0045137 107 0.021
positive regulation of neuron differentiation GO:0045666 126 0.021
response to reactive oxygen species GO:0000302 120 0.021
response to peptide hormone GO:0043434 278 0.021
circulatory system process GO:0003013 183 0.021
regulation of metal ion transport GO:0010959 118 0.021
regulation of calcium ion transport GO:0051924 77 0.021
regulation of immune system process GO:0002682 123 0.020
organic hydroxy compound biosynthetic process GO:1901617 51 0.020
cell morphogenesis involved in differentiation GO:0000904 119 0.020
positive regulation of cell development GO:0010720 176 0.020
regulation of protein metabolic process GO:0051246 289 0.020
positive regulation of cellular component movement GO:0051272 102 0.020
dendrite development GO:0016358 72 0.020
sex differentiation GO:0007548 113 0.020
Worm
regulation of angiogenesis GO:0045765 39 0.020
positive regulation of neurogenesis GO:0050769 165 0.020
organ formation GO:0048645 3 0.020
Fly
response to acid chemical GO:0001101 222 0.020
single organism organelle organization GO:1902589 180 0.020
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.020
synaptic transmission GO:0007268 235 0.019
cation homeostasis GO:0055080 195 0.019
positive regulation of locomotion GO:0040017 102 0.019
positive regulation of serotonin secretion GO:0014064 1 0.019
positive regulation of hormone secretion GO:0046887 65 0.019
cellular response to glucose stimulus GO:0071333 65 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
glucose homeostasis GO:0042593 75 0.019
rhythmic process GO:0048511 156 0.019
vesicle mediated transport GO:0016192 181 0.019
protein localization GO:0008104 191 0.019
regulation of cell projection organization GO:0031344 175 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.019
Fly
calcium ion transport GO:0006816 131 0.019
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
Mouse
catabolic process GO:0009056 351 0.019
tube development GO:0035295 89 0.019
hematopoietic progenitor cell differentiation GO:0002244 2 0.018
cell part morphogenesis GO:0032990 123 0.018
steroid metabolic process GO:0008202 73 0.018
cellular response to lipid GO:0071396 201 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
digestion GO:0007586 26 0.018
regulation of phosphorus metabolic process GO:0051174 349 0.018
cellular hormone metabolic process GO:0034754 49 0.018
multi organism reproductive process GO:0044703 262 0.018
organic acid biosynthetic process GO:0016053 83 0.018
regulation of mapk cascade GO:0043408 116 0.018
leukocyte differentiation GO:0002521 30 0.018
sexual reproduction GO:0019953 148 0.017
cell type specific apoptotic process GO:0097285 134 0.017
Mouse
positive regulation of cell motility GO:2000147 97 0.017
positive regulation of programmed cell death GO:0043068 157 0.017
gonad development GO:0008406 104 0.017
regulation of calcium ion dependent exocytosis GO:0017158 11 0.017
negative regulation of ion transport GO:0043271 51 0.017
cellular catabolic process GO:0044248 295 0.017
protein oligomerization GO:0051259 191 0.017
female pregnancy GO:0007565 122 0.017
muscle cell proliferation GO:0033002 84 0.017
regulation of locomotion GO:0040012 148 0.017
positive regulation of secretion by cell GO:1903532 128 0.017
cell projection morphogenesis GO:0048858 123 0.017
regulation of smooth muscle cell proliferation GO:0048660 75 0.016
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.016
gland development GO:0048732 155 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
regulation of transmembrane transport GO:0034762 122 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
positive regulation of angiogenesis GO:0045766 28 0.016
positive regulation of molecular function GO:0044093 230 0.016
cellular response to reactive oxygen species GO:0034614 55 0.016
regulation of ion transmembrane transporter activity GO:0032412 48 0.016
cellular response to hexose stimulus GO:0071331 65 0.016
positive regulation of ion transport GO:0043270 94 0.016
macromolecule localization GO:0033036 252 0.016
regulation of ion transport GO:0043269 245 0.016
cellular response to glucocorticoid stimulus GO:0071385 68 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
Mouse Worm
regulation of molecular function GO:0065009 398 0.015
response to wounding GO:0009611 254 0.015
regulation of membrane potential GO:0042391 110 0.015
defecation GO:0030421 1 0.015
inflammatory response GO:0006954 150 0.015
cellular response to corticosteroid stimulus GO:0071384 69 0.015
negative regulation of cellular component organization GO:0051129 83 0.015
neuron projection morphogenesis GO:0048812 122 0.015
cellular amide metabolic process GO:0043603 44 0.015
axonogenesis GO:0007409 71 0.015
heart development GO:0007507 72 0.015
hormone mediated signaling pathway GO:0009755 23 0.015
peptide hormone secretion GO:0030072 84 0.015
muscle structure development GO:0061061 87 0.015
cellular amine metabolic process GO:0044106 38 0.015
immune response GO:0006955 104 0.014
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.014
oxoacid metabolic process GO:0043436 290 0.014
anatomical structure formation involved in morphogenesis GO:0048646 83 0.014
Fly
negative regulation of calcium ion import GO:0090281 2 0.014
establishment of protein localization GO:0045184 141 0.014
regulation of neural precursor cell proliferation GO:2000177 16 0.014
organ morphogenesis GO:0009887 75 0.014
Fly
defense response GO:0006952 194 0.014
response to calcium ion GO:0051592 59 0.014
lipid biosynthetic process GO:0008610 128 0.014
muscle tissue development GO:0060537 58 0.014
detection of calcium ion GO:0005513 1 0.014
regulation of protein modification process GO:0031399 194 0.014
cellular macromolecule localization GO:0070727 122 0.014
s shaped body morphogenesis GO:0072050 2 0.014
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.014
vasculature development GO:0001944 70 0.014
exocytosis GO:0006887 60 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
organic hydroxy compound transport GO:0015850 77 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
negative regulation of cell development GO:0010721 82 0.013
bone development GO:0060348 25 0.013
chemotaxis GO:0006935 66 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
eye morphogenesis GO:0048592 4 0.013
Fly
multi multicellular organism process GO:0044706 138 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
negative regulation of hormone secretion GO:0046888 46 0.013
regulation of cellular ketone metabolic process GO:0010565 27 0.013
muscle contraction GO:0006936 88 0.013
response to axon injury GO:0048678 59 0.013
regulation of mrna splicing via spliceosome GO:0048024 3 0.013
response to oxygen levels GO:0070482 265 0.013
response to ethanol GO:0045471 162 0.013
learning GO:0007612 33 0.012
myeloid leukocyte differentiation GO:0002573 20 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
cellular response to monosaccharide stimulus GO:0071326 67 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
male mating behavior GO:0060179 3 0.012
actin filament based process GO:0030029 86 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
phosphatidylinositol dephosphorylation GO:0046856 4 0.012
protein phosphorylation GO:0006468 345 0.012
negative regulation of cell death GO:0060548 229 0.012
Mouse Worm
cellular glucose homeostasis GO:0001678 66 0.012
axis specification GO:0009798 4 0.012
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.012
neuron fate commitment GO:0048663 4 0.012
digestive system process GO:0022600 24 0.012
regeneration GO:0031099 163 0.012
carboxylic acid metabolic process GO:0019752 289 0.012
neural precursor cell proliferation GO:0061351 23 0.012
detection of chemical stimulus GO:0009593 10 0.012
regulation of muscle contraction GO:0006937 53 0.012
heart contraction GO:0060047 57 0.012
heart process GO:0003015 57 0.012
intracellular transport GO:0046907 185 0.012
divalent metal ion transport GO:0070838 132 0.011
reproductive structure development GO:0048608 128 0.011
regulation of muscle system process GO:0090257 79 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
Mouse
positive regulation of protein modification process GO:0031401 142 0.011
cellular protein localization GO:0034613 122 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
endoplasmic reticulum organization GO:0007029 1 0.011
regulation of vasculature development GO:1901342 44 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
cell fate determination GO:0001709 2 0.011
negative regulation of camp metabolic process GO:0030815 14 0.011
ossification GO:0001503 70 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
ras protein signal transduction GO:0007265 29 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
lymphocyte migration GO:0072676 3 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
regulation of erk1 and erk2 cascade GO:0070372 41 0.011
positive regulation of immune system process GO:0002684 90 0.011
intracellular receptor signaling pathway GO:0030522 35 0.011
phospholipid metabolic process GO:0006644 61 0.011
amine metabolic process GO:0009308 38 0.010
bmp signaling pathway GO:0030509 4 0.010
response to ionizing radiation GO:0010212 59 0.010
positive regulation of insulin secretion GO:0032024 36 0.010
endomembrane system organization GO:0010256 48 0.010
circadian rhythm GO:0007623 88 0.010
regulation of defense response GO:0031347 68 0.010
anion transport GO:0006820 178 0.010
multicellular organismal response to stress GO:0033555 25 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
urinary bladder smooth muscle contraction GO:0014832 4 0.010
erk1 and erk2 cascade GO:0070371 48 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
regulation of regulated secretory pathway GO:1903305 7 0.010
cellular protein complex assembly GO:0043623 44 0.010

Barhl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.056
nervous system disease DOID:863 0 0.056
central nervous system disease DOID:331 0 0.018
musculoskeletal system disease DOID:17 0 0.013
connective tissue disease DOID:65 0 0.012