Rattus norvegicus

32 known processes

Mb

myoglobin

Mb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cardiac muscle contraction GO:0060048 27 0.421
muscle contraction GO:0006936 88 0.320
striated muscle contraction GO:0006941 44 0.254
actin myosin filament sliding GO:0033275 2 0.252
circulatory system process GO:0003013 183 0.195
blood circulation GO:0008015 183 0.183
aromatic compound catabolic process GO:0019439 168 0.177
heart morphogenesis GO:0003007 3 0.137
carbohydrate derivative catabolic process GO:1901136 147 0.126
organic substance catabolic process GO:1901575 316 0.121
response to muscle stretch GO:0035994 2 0.117
cardiac myofibril assembly GO:0055003 1 0.112
cellular component morphogenesis GO:0032989 155 0.109
muscle filament sliding GO:0030049 2 0.106
organophosphate metabolic process GO:0019637 370 0.099
cell projection morphogenesis GO:0048858 123 0.095
nucleotide catabolic process GO:0009166 139 0.094
cellular catabolic process GO:0044248 295 0.094
purine nucleoside monophosphate catabolic process GO:0009128 55 0.091
catabolic process GO:0009056 351 0.090
cardiac muscle tissue morphogenesis GO:0055008 1 0.089
heart contraction GO:0060047 57 0.084
glycosyl compound metabolic process GO:1901657 182 0.084
regulation of establishment of planar polarity GO:0090175 2 0.083
purine nucleoside triphosphate catabolic process GO:0009146 122 0.082
nucleobase containing compound catabolic process GO:0034655 152 0.082
cardiovascular system development GO:0072358 134 0.071
Mouse
purine containing compound catabolic process GO:0072523 138 0.071
purine ribonucleotide catabolic process GO:0009154 136 0.071
heart process GO:0003015 57 0.070
organonitrogen compound catabolic process GO:1901565 179 0.070
lipid metabolic process GO:0006629 283 0.070
cellular nitrogen compound catabolic process GO:0044270 163 0.070
circulatory system development GO:0072359 134 0.069
Mouse
organophosphate catabolic process GO:0046434 148 0.067
muscle system process GO:0003012 115 0.067
ribonucleoside metabolic process GO:0009119 174 0.066
purine ribonucleoside catabolic process GO:0046130 124 0.066
purine nucleoside triphosphate metabolic process GO:0009144 141 0.065
actin filament based movement GO:0030048 16 0.062
ribonucleoside triphosphate metabolic process GO:0009199 141 0.062
anatomical structure morphogenesis GO:0009653 298 0.061
nucleoside triphosphate catabolic process GO:0009143 123 0.061
regulation of system process GO:0044057 208 0.060
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.059
response to metal ion GO:0010038 253 0.059
ribonucleoside catabolic process GO:0042454 126 0.058
single organism catabolic process GO:0044712 283 0.058
heterocycle catabolic process GO:0046700 167 0.057
homeostatic process GO:0042592 331 0.056
Mouse
striated muscle tissue development GO:0014706 58 0.056
ribonucleoside triphosphate catabolic process GO:0009203 122 0.055
multicellular organism reproduction GO:0032504 233 0.054
nucleoside triphosphate metabolic process GO:0009141 144 0.053
organic cyclic compound catabolic process GO:1901361 175 0.051
organelle organization GO:0006996 266 0.050
organic acid metabolic process GO:0006082 292 0.050
glycosyl compound catabolic process GO:1901658 126 0.049
nucleoside phosphate catabolic process GO:1901292 140 0.049
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.049
purine nucleotide catabolic process GO:0006195 136 0.047
anatomical structure formation involved in morphogenesis GO:0048646 83 0.047
protein complex subunit organization GO:0071822 302 0.046
purine nucleoside monophosphate metabolic process GO:0009126 84 0.046
tissue development GO:0009888 252 0.045
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.045
cellular component biogenesis GO:0044085 368 0.044
purine nucleoside catabolic process GO:0006152 124 0.042
muscle organ morphogenesis GO:0048644 1 0.042
purine ribonucleoside metabolic process GO:0046128 168 0.041
oxoacid metabolic process GO:0043436 290 0.041
nucleoside metabolic process GO:0009116 179 0.041
cell projection organization GO:0030030 302 0.041
negative regulation of metabolic process GO:0009892 331 0.041
cardiac muscle cell development GO:0055013 16 0.039
programmed cell death GO:0012501 392 0.039
carbohydrate derivative metabolic process GO:1901135 346 0.039
nucleotide metabolic process GO:0009117 279 0.036
regulation of muscle system process GO:0090257 79 0.036
regulation of cellular component movement GO:0051270 150 0.036
actin filament based process GO:0030029 86 0.036
chemical homeostasis GO:0048878 292 0.035
ribonucleotide catabolic process GO:0009261 136 0.035
regulation of multicellular organismal development GO:2000026 376 0.035
response to peptide GO:1901652 292 0.035
heart development GO:0007507 72 0.034
Mouse
purine nucleotide metabolic process GO:0006163 229 0.033
nucleoside monophosphate metabolic process GO:0009123 93 0.033
macromolecular complex assembly GO:0065003 273 0.033
nucleobase containing small molecule metabolic process GO:0055086 316 0.033
muscle structure development GO:0061061 87 0.032
macromolecular complex subunit organization GO:0043933 339 0.032
response to hypoxia GO:0001666 231 0.032
Mouse
actin mediated cell contraction GO:0070252 12 0.032
nucleoside catabolic process GO:0009164 126 0.031
ribonucleoside monophosphate metabolic process GO:0009161 88 0.031
regulation of rna biosynthetic process GO:2001141 381 0.031
regulation of nucleic acid templated transcription GO:1903506 380 0.031
purine nucleoside metabolic process GO:0042278 169 0.030
multi organism reproductive process GO:0044703 262 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.029
response to oxidative stress GO:0006979 186 0.029
regulation of rna metabolic process GO:0051252 391 0.029
myofibril assembly GO:0030239 6 0.029
cardiocyte differentiation GO:0035051 22 0.028
cardiac ventricle development GO:0003231 1 0.027
apoptotic process GO:0006915 381 0.027
nucleoside phosphate metabolic process GO:0006753 283 0.027
response to nutrient levels GO:0031667 370 0.026
single organism carbohydrate metabolic process GO:0044723 118 0.026
muscle tissue development GO:0060537 58 0.026
cardiac muscle cell contraction GO:0086003 10 0.026
defense response GO:0006952 194 0.026
atp metabolic process GO:0046034 72 0.025
regulation of blood circulation GO:1903522 110 0.025
regulation of muscle contraction GO:0006937 53 0.024
cell part morphogenesis GO:0032990 123 0.024
single organism organelle organization GO:1902589 180 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.024
cardiac cell development GO:0055006 16 0.024
establishment of tissue polarity GO:0007164 2 0.024
organ morphogenesis GO:0009887 75 0.024
ribonucleoside monophosphate catabolic process GO:0009158 55 0.023
cellular response to abiotic stimulus GO:0071214 85 0.023
regulation of cellular component organization GO:0051128 368 0.023
response to inorganic substance GO:0010035 377 0.023
protein complex biogenesis GO:0070271 263 0.023
metal ion transport GO:0030001 289 0.023
skeletal muscle tissue development GO:0007519 31 0.023
nucleoside monophosphate catabolic process GO:0009125 56 0.022
locomotion GO:0040011 237 0.022
rna biosynthetic process GO:0032774 380 0.022
response to extracellular stimulus GO:0009991 380 0.022
cellular homeostasis GO:0019725 252 0.022
rna metabolic process GO:0016070 406 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.022
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 3 0.022
reproductive process GO:0022414 372 0.022
twitch skeletal muscle contraction GO:0014721 3 0.022
ribose phosphate metabolic process GO:0019693 235 0.021
neuron differentiation GO:0030182 368 0.021
neuron projection morphogenesis GO:0048812 122 0.021
positive regulation of developmental process GO:0051094 283 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
striated muscle cell development GO:0055002 26 0.021
voluntary skeletal muscle contraction GO:0003010 3 0.021
cellular amino acid metabolic process GO:0006520 107 0.020
nucleic acid templated transcription GO:0097659 379 0.020
ion transmembrane transport GO:0034220 365 0.020
cellular ion homeostasis GO:0006873 184 0.020
response to other organism GO:0051707 220 0.020
response to decreased oxygen levels GO:0036293 237 0.020
Mouse
regulation of catalytic activity GO:0050790 304 0.020
cellular component assembly GO:0022607 360 0.020
neuron development GO:0048666 286 0.020
carbohydrate metabolic process GO:0005975 130 0.019
cardiac chamber development GO:0003205 1 0.019
cold acclimation GO:0009631 1 0.019
protein complex assembly GO:0006461 263 0.019
regulation of heart contraction GO:0008016 48 0.019
regulation of cell differentiation GO:0045595 320 0.019
female pregnancy GO:0007565 122 0.019
intestinal absorption GO:0050892 3 0.019
response to wounding GO:0009611 254 0.019
cytoskeleton organization GO:0007010 111 0.019
cellular amine metabolic process GO:0044106 38 0.019
regulation of striated muscle contraction GO:0006942 21 0.018
myosin filament organization GO:0031033 2 0.018
cellular component movement GO:0006928 248 0.018
response to peptide hormone GO:0043434 278 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
wound healing GO:0042060 122 0.018
response to electrical stimulus involved in regulation of muscle adaptation GO:0014878 4 0.018
cellular chemical homeostasis GO:0055082 247 0.018
transcription dna templated GO:0006351 377 0.018
carboxylic acid metabolic process GO:0019752 289 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.018
central nervous system development GO:0007417 311 0.018
regulation of stem cell differentiation GO:2000736 2 0.018
cardiac muscle tissue development GO:0048738 26 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
response to mechanical stimulus GO:0009612 134 0.017
purine containing compound metabolic process GO:0072521 253 0.017
growth GO:0040007 165 0.017
negative regulation of cell death GO:0060548 229 0.017
oxidation reduction process GO:0055114 304 0.017
Rat
metal ion homeostasis GO:0055065 186 0.017
ion homeostasis GO:0050801 212 0.017
cellular modified amino acid metabolic process GO:0006575 61 0.017
response to reactive oxygen species GO:0000302 120 0.017
skeletal muscle fiber adaptation GO:0043503 1 0.017
regulation of apoptotic process GO:0042981 335 0.017
potassium ion transmembrane transport GO:0071805 71 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
developmental growth GO:0048589 100 0.016
muscle tissue morphogenesis GO:0060415 1 0.016
neuron projection development GO:0031175 273 0.016
brain development GO:0007420 247 0.015
cardiac conduction GO:0061337 2 0.015
gland development GO:0048732 155 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.015
positive regulation of cell communication GO:0010647 271 0.015
cell growth GO:0016049 104 0.015
regulation of phosphorylation GO:0042325 248 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
cellular protein complex assembly GO:0043623 44 0.015
regulation of cardiac muscle contraction GO:0055117 17 0.015
single organism biosynthetic process GO:0044711 342 0.015
establishment of planar polarity GO:0001736 1 0.015
neuromuscular synaptic transmission GO:0007274 2 0.015
regulation of molecular function GO:0065009 398 0.014
cellular lipid metabolic process GO:0044255 208 0.014
hepaticobiliary system development GO:0061008 90 0.014
gamete generation GO:0007276 124 0.014
regulation of neuron differentiation GO:0045664 208 0.014
muscle cell differentiation GO:0042692 52 0.014
organelle assembly GO:0070925 22 0.014
regulation of phosphorus metabolic process GO:0051174 349 0.014
positive regulation of signal transduction GO:0009967 175 0.014
tissue morphogenesis GO:0048729 22 0.014
monocarboxylic acid metabolic process GO:0032787 152 0.014
cellular macromolecule localization GO:0070727 122 0.014
cellular protein localization GO:0034613 122 0.014
spermatogenesis GO:0007283 99 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
response to bacterium GO:0009617 200 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
camera type eye development GO:0043010 48 0.013
positive regulation of molecular function GO:0044093 230 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
regulation of cell proliferation GO:0042127 359 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
positive regulation of gene expression GO:0010628 244 0.013
amine metabolic process GO:0009308 38 0.013
head development GO:0060322 247 0.013
sexual reproduction GO:0019953 148 0.013
cellular ketone metabolic process GO:0042180 51 0.012
nitrogen compound transport GO:0071705 229 0.012
cell morphogenesis GO:0000902 142 0.012
atp catabolic process GO:0006200 54 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
regulation of programmed cell death GO:0043067 341 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
regeneration GO:0031099 163 0.012
membrane depolarization during action potential GO:0086010 1 0.012
cellular response to external stimulus GO:0071496 118 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
response to glucocorticoid GO:0051384 223 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
positive regulation of rna metabolic process GO:0051254 203 0.012
regulation of cytokine production GO:0001817 56 0.012
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.012
regulation of transcription dna templated GO:0006355 374 0.012
cation transport GO:0006812 382 0.012
sarcomere organization GO:0045214 6 0.012
regulation of purine nucleotide catabolic process GO:0033121 65 0.012
cellular response to stress GO:0033554 269 0.012
regulation of neuron projection development GO:0010975 161 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
transmembrane transport GO:0055085 412 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.011
developmental process involved in reproduction GO:0003006 159 0.011
diterpenoid metabolic process GO:0016101 33 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
regulation of anatomical structure size GO:0090066 135 0.011
cellular response to oxygen containing compound GO:1901701 386 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
respiratory system process GO:0003016 3 0.011
dna metabolic process GO:0006259 96 0.011
cellular cation homeostasis GO:0030003 180 0.011
cell fate determination GO:0001709 2 0.011
single organism reproductive process GO:0044702 297 0.011
terpenoid metabolic process GO:0006721 37 0.011
actomyosin structure organization GO:0031032 22 0.011
cellular response to oxidative stress GO:0034599 76 0.011
positive regulation of catabolic process GO:0009896 78 0.011
response to lipopolysaccharide GO:0032496 191 0.011
intracellular signal transduction GO:0035556 314 0.011
cell type specific apoptotic process GO:0097285 134 0.011
cellular modified amino acid biosynthetic process GO:0042398 18 0.011
negative regulation of cellular metabolic process GO:0031324 281 0.011
response to purine containing compound GO:0014074 126 0.011
protein phosphorylation GO:0006468 345 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
cellular amino acid biosynthetic process GO:0008652 32 0.011
multicellular organismal reproductive process GO:0048609 233 0.011
generation of precursor metabolites and energy GO:0006091 62 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
monosaccharide metabolic process GO:0005996 61 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
multi multicellular organism process GO:0044706 138 0.011
adult locomotory behavior GO:0008344 4 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.010
cardiac muscle cell action potential involved in contraction GO:0086002 2 0.010
response to fatty acid GO:0070542 65 0.010
positive regulation of protein modification process GO:0031401 142 0.010
gastrulation GO:0007369 2 0.010
myosin filament assembly GO:0031034 1 0.010
regulation of cell projection organization GO:0031344 175 0.010
multicellular organismal signaling GO:0035637 44 0.010
positive regulation of cell development GO:0010720 176 0.010
negative regulation of gene expression GO:0010629 199 0.010
male gamete generation GO:0048232 99 0.010
response to nutrient GO:0007584 248 0.010
meiotic cell cycle process GO:1903046 3 0.010
regulation of cellular amino acid metabolic process GO:0006521 2 0.010
bmp signaling pathway GO:0030509 4 0.010
response to biotic stimulus GO:0009607 226 0.010
reproduction GO:0000003 245 0.010
monovalent inorganic cation transport GO:0015672 172 0.010
negative regulation of cellular biosynthetic process GO:0031327 161 0.010
slow twitch skeletal muscle fiber contraction GO:0031444 2 0.010

Mb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.887
muscular disease DOID:0080000 0 0.887
heart disease DOID:114 0 0.887
cardiomyopathy DOID:0050700 0 0.887
disease of anatomical entity DOID:7 0 0.887
intrinsic cardiomyopathy DOID:0060036 0 0.887
cardiovascular system disease DOID:1287 0 0.887
musculoskeletal system disease DOID:17 0 0.887
muscle tissue disease DOID:66 0 0.887
hypertrophic cardiomyopathy DOID:11984 0 0.613
dilated cardiomyopathy DOID:12930 0 0.232
muscular dystrophy DOID:9884 0 0.013
congenital heart disease DOID:1682 0 0.011
heart septal defect DOID:1681 0 0.011
disease of metabolism DOID:0014667 0 0.010