Rattus norvegicus

0 known processes

Dusp18

dual specificity phosphatase 18

Dusp18 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
nucleoside phosphate metabolic process GO:0006753 283 0.066
regulation of phosphorus metabolic process GO:0051174 349 0.064
regulation of phosphate metabolic process GO:0019220 349 0.048
positive regulation of phosphorus metabolic process GO:0010562 262 0.047
purine ribonucleotide metabolic process GO:0009150 227 0.047
organophosphate metabolic process GO:0019637 370 0.044
rna biosynthetic process GO:0032774 380 0.044
regulation of molecular function GO:0065009 398 0.043
carbohydrate derivative metabolic process GO:1901135 346 0.042
response to peptide hormone GO:0043434 278 0.041
purine containing compound metabolic process GO:0072521 253 0.041
positive regulation of phosphate metabolic process GO:0045937 262 0.040
regulation of protein metabolic process GO:0051246 289 0.039
response to inorganic substance GO:0010035 377 0.039
regulation of catalytic activity GO:0050790 304 0.037
regulation of signal transduction GO:0009966 318 0.037
purine nucleotide metabolic process GO:0006163 229 0.036
reproductive process GO:0022414 372 0.035
nucleobase containing small molecule metabolic process GO:0055086 316 0.035
ribose phosphate metabolic process GO:0019693 235 0.035
ribonucleotide metabolic process GO:0009259 231 0.035
protein phosphorylation GO:0006468 345 0.035
nucleotide metabolic process GO:0009117 279 0.034
catabolic process GO:0009056 351 0.033
macromolecular complex subunit organization GO:0043933 339 0.033
single organism reproductive process GO:0044702 297 0.033
negative regulation of metabolic process GO:0009892 331 0.032
cellular component biogenesis GO:0044085 368 0.032
organic acid metabolic process GO:0006082 292 0.032
programmed cell death GO:0012501 392 0.032
apoptotic process GO:0006915 381 0.032
regulation of hydrolase activity GO:0051336 143 0.030
intracellular signal transduction GO:0035556 314 0.030
response to acid chemical GO:0001101 222 0.030
single organism biosynthetic process GO:0044711 342 0.030
negative regulation of cellular metabolic process GO:0031324 281 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.029
regulation of apoptotic process GO:0042981 335 0.029
carboxylic acid metabolic process GO:0019752 289 0.029
positive regulation of biosynthetic process GO:0009891 319 0.029
cell projection organization GO:0030030 302 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.029
oxoacid metabolic process GO:0043436 290 0.029
transcription dna templated GO:0006351 377 0.029
protein complex subunit organization GO:0071822 302 0.029
cellular amino acid metabolic process GO:0006520 107 0.029
regulation of cell differentiation GO:0045595 320 0.029
response to peptide GO:1901652 292 0.028
positive regulation of multicellular organismal process GO:0051240 387 0.027
cellular component assembly GO:0022607 360 0.027
nucleoside catabolic process GO:0009164 126 0.027
regulation of programmed cell death GO:0043067 341 0.027
nucleoside triphosphate catabolic process GO:0009143 123 0.027
regulation of nucleic acid templated transcription GO:1903506 380 0.027
cellular amine metabolic process GO:0044106 38 0.027
nucleic acid templated transcription GO:0097659 379 0.026
regulation of protein modification process GO:0031399 194 0.026
ras protein signal transduction GO:0007265 29 0.026
small gtpase mediated signal transduction GO:0007264 36 0.026
organelle organization GO:0006996 266 0.026
negative regulation of apoptotic process GO:0043066 181 0.025
negative regulation of gene expression GO:0010629 199 0.025
macromolecule localization GO:0033036 252 0.025
amine metabolic process GO:0009308 38 0.025
positive regulation of nucleotide metabolic process GO:0045981 91 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
rna metabolic process GO:0016070 406 0.025
single organism catabolic process GO:0044712 283 0.025
regulation of cellular protein metabolic process GO:0032268 267 0.024
glycosyl compound metabolic process GO:1901657 182 0.024
homeostatic process GO:0042592 331 0.024
regulation of transcription dna templated GO:0006355 374 0.024
regulation of rna biosynthetic process GO:2001141 381 0.024
response to cytokine GO:0034097 215 0.024
response to decreased oxygen levels GO:0036293 237 0.023
regulation of secretion by cell GO:1903530 208 0.023
regulation of cellular ketone metabolic process GO:0010565 27 0.023
nucleoside metabolic process GO:0009116 179 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
regulation of cellular localization GO:0060341 263 0.023
single organism organelle organization GO:1902589 180 0.023
organophosphate catabolic process GO:0046434 148 0.023
organic substance catabolic process GO:1901575 316 0.023
response to growth factor GO:0070848 189 0.023
aromatic compound catabolic process GO:0019439 168 0.022
macromolecular complex assembly GO:0065003 273 0.022
positive regulation of molecular function GO:0044093 230 0.022
cytoskeleton organization GO:0007010 111 0.022
cellular ketone metabolic process GO:0042180 51 0.022
cellular response to endogenous stimulus GO:0071495 377 0.022
regulation of multicellular organismal development GO:2000026 376 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
response to extracellular stimulus GO:0009991 380 0.022
developmental process involved in reproduction GO:0003006 159 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
aging GO:0007568 241 0.022
regulation of rna metabolic process GO:0051252 391 0.022
purine ribonucleotide catabolic process GO:0009154 136 0.021
cellular component morphogenesis GO:0032989 155 0.021
chemical homeostasis GO:0048878 292 0.021
response to hypoxia GO:0001666 231 0.021
secretion GO:0046903 307 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
ribonucleoside catabolic process GO:0042454 126 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
organic cyclic compound catabolic process GO:1901361 175 0.021
purine ribonucleoside metabolic process GO:0046128 168 0.021
regulation of intracellular signal transduction GO:1902531 218 0.021
neuron projection development GO:0031175 273 0.021
multi organism reproductive process GO:0044703 262 0.021
purine nucleoside triphosphate metabolic process GO:0009144 141 0.021
cellular catabolic process GO:0044248 295 0.021
mapk cascade GO:0000165 140 0.020
cell cell signaling GO:0007267 335 0.020
purine nucleotide catabolic process GO:0006195 136 0.020
embryonic pattern specification GO:0009880 1 0.020
purine nucleoside metabolic process GO:0042278 169 0.020
regulation of phosphorylation GO:0042325 248 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
sex differentiation GO:0007548 113 0.020
regulation of cell proliferation GO:0042127 359 0.020
ribonucleotide catabolic process GO:0009261 136 0.020
negative regulation of cell communication GO:0010648 158 0.020
cation transport GO:0006812 382 0.020
reproduction GO:0000003 245 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
cellular response to stress GO:0033554 269 0.020
ribonucleoside metabolic process GO:0009119 174 0.020
cellular response to oxygen containing compound GO:1901701 386 0.020
positive regulation of rna biosynthetic process GO:1902680 197 0.020
response to metal ion GO:0010038 253 0.019
cellular component movement GO:0006928 248 0.019
regulation of cellular component organization GO:0051128 368 0.019
nucleoside phosphate catabolic process GO:1901292 140 0.019
establishment of protein localization GO:0045184 141 0.019
intracellular transport GO:0046907 185 0.019
small molecule biosynthetic process GO:0044283 124 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
signal transduction by phosphorylation GO:0023014 144 0.019
heterocycle catabolic process GO:0046700 167 0.018
regulation of nervous system development GO:0051960 264 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
purine ribonucleoside catabolic process GO:0046130 124 0.018
purine nucleoside triphosphate catabolic process GO:0009146 122 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
regulation of purine nucleotide metabolic process GO:1900542 115 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
regulation of cell motility GO:2000145 131 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.018
sexual reproduction GO:0019953 148 0.018
cell motility GO:0048870 202 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
negative regulation of protein metabolic process GO:0051248 114 0.018
single organism intracellular transport GO:1902582 166 0.018
response to wounding GO:0009611 254 0.018
positive regulation of developmental process GO:0051094 283 0.017
ribonucleoside triphosphate catabolic process GO:0009203 122 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
neuron development GO:0048666 286 0.017
reproductive structure development GO:0048608 128 0.017
regulation of catabolic process GO:0009894 113 0.017
nucleotide catabolic process GO:0009166 139 0.017
regulation of synaptic transmission GO:0050804 141 0.017
neuron differentiation GO:0030182 368 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
growth GO:0040007 165 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
cellular nitrogen compound catabolic process GO:0044270 163 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
negative regulation of cell death GO:0060548 229 0.017
axis specification GO:0009798 4 0.017
response to oxygen levels GO:0070482 265 0.017
guanosine containing compound metabolic process GO:1901068 74 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.017
purine containing compound catabolic process GO:0072523 138 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
multicellular organism reproduction GO:0032504 233 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
positive regulation of signaling GO:0023056 270 0.016
purine nucleoside catabolic process GO:0006152 124 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
response to oxidative stress GO:0006979 186 0.016
protein complex biogenesis GO:0070271 263 0.016
regulation of neurogenesis GO:0050767 247 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.016
positive regulation of gene expression GO:0010628 244 0.016
glycosyl compound catabolic process GO:1901658 126 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
organophosphate biosynthetic process GO:0090407 143 0.016
response to nutrient levels GO:0031667 370 0.016
secretion by cell GO:0032940 248 0.016
negative regulation of signaling GO:0023057 157 0.016
gonad development GO:0008406 104 0.016
cell projection morphogenesis GO:0048858 123 0.016
response to insulin GO:0032868 133 0.016
cell morphogenesis GO:0000902 142 0.016
negative regulation of molecular function GO:0044092 133 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.015
positive regulation of cell communication GO:0010647 271 0.015
gtp catabolic process GO:0006184 71 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
response to corticosteroid GO:0031960 235 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
lipid metabolic process GO:0006629 283 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
regulation of neuron projection development GO:0010975 161 0.015
regulation of hormone levels GO:0010817 187 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
gland development GO:0048732 155 0.015
response to glucocorticoid GO:0051384 223 0.015
regulation of small gtpase mediated signal transduction GO:0051056 48 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
response to hexose GO:0009746 144 0.014
response to monosaccharide GO:0034284 159 0.014
development of primary sexual characteristics GO:0045137 107 0.014
response to purine containing compound GO:0014074 126 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
regulation of system process GO:0044057 208 0.014
regulation of blood circulation GO:1903522 110 0.014
localization of cell GO:0051674 202 0.014
regulation of response to stress GO:0080134 126 0.014
positive regulation of signal transduction GO:0009967 175 0.014
reproductive system development GO:0061458 128 0.014
regulation of cell projection organization GO:0031344 175 0.014
anatomical structure formation involved in morphogenesis GO:0048646 83 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.014
hormone transport GO:0009914 121 0.014
central nervous system development GO:0007417 311 0.014
protein transport GO:0015031 132 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
response to carbohydrate GO:0009743 183 0.014
synaptic transmission GO:0007268 235 0.014
protein localization GO:0008104 191 0.014
tissue development GO:0009888 252 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.013
positive regulation of nervous system development GO:0051962 178 0.013
protein complex assembly GO:0006461 263 0.013
cardiovascular system development GO:0072358 134 0.013
cellular homeostasis GO:0019725 252 0.013
rhythmic process GO:0048511 156 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
response to reactive oxygen species GO:0000302 120 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
response to glucose GO:0009749 136 0.013
cellular cation homeostasis GO:0030003 180 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
regulation of nucleotide catabolic process GO:0030811 65 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
negative regulation of innate immune response GO:0045824 4 0.013
head development GO:0060322 247 0.013
erythrocyte differentiation GO:0030218 1 0.013
positive regulation of protein modification process GO:0031401 142 0.013
signal release GO:0023061 145 0.013
locomotion GO:0040011 237 0.013
regulation of cellular component movement GO:0051270 150 0.013
blood circulation GO:0008015 183 0.013
response to mechanical stimulus GO:0009612 134 0.013
salivary gland development GO:0007431 3 0.013
regulation of neuron differentiation GO:0045664 208 0.013
gtp metabolic process GO:0046039 72 0.012
metal ion transport GO:0030001 289 0.012
response to estradiol GO:0032355 164 0.012
lipid biosynthetic process GO:0008610 128 0.012
erythrocyte homeostasis GO:0034101 2 0.012
actin filament based process GO:0030029 86 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
cellular response to external stimulus GO:0071496 118 0.012
transmembrane transport GO:0055085 412 0.012
proteolysis GO:0006508 175 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
appendage morphogenesis GO:0035107 4 0.012
brain development GO:0007420 247 0.012
regulation of purine nucleotide catabolic process GO:0033121 65 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
regulation of kinase activity GO:0043549 117 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
guanosine containing compound catabolic process GO:1901069 71 0.012
response to external biotic stimulus GO:0043207 221 0.012
cell adhesion GO:0007155 110 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
eye morphogenesis GO:0048592 4 0.012
cytoplasmic transport GO:0016482 115 0.012
regulation of cell development GO:0060284 263 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
development of primary female sexual characteristics GO:0046545 56 0.012
immune system process GO:0002376 204 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
purine containing compound biosynthetic process GO:0072522 85 0.011
regulation of nucleoside metabolic process GO:0009118 66 0.011
gastrulation GO:0007369 2 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
heart morphogenesis GO:0003007 3 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
ion transmembrane transport GO:0034220 365 0.011
response to estrogen GO:0043627 232 0.011
regulation of mapk cascade GO:0043408 116 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
female sex differentiation GO:0046660 59 0.011
positive regulation of gtpase activity GO:0043547 47 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
regulation of secretion GO:0051046 224 0.011
regulation of cell cycle GO:0051726 73 0.011
rna localization GO:0006403 4 0.011
hormone secretion GO:0046879 115 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
response to ketone GO:1901654 182 0.011
wound healing GO:0042060 122 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
response to amino acid GO:0043200 75 0.011
liver development GO:0001889 90 0.011
protein oligomerization GO:0051259 191 0.011
circulatory system process GO:0003013 183 0.011
response to nutrient GO:0007584 248 0.011
negative regulation of secretion GO:0051048 82 0.011
spermatogenesis GO:0007283 99 0.011
olfactory behavior GO:0042048 2 0.011
positive regulation of nucleoside metabolic process GO:0045979 55 0.011
regulation of gtpase activity GO:0043087 57 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
anterior posterior pattern specification GO:0009952 1 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
gamete generation GO:0007276 124 0.011
positive regulation of cell death GO:0010942 184 0.011
positive regulation of cell development GO:0010720 176 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
vesicle mediated transport GO:0016192 181 0.011
male sex differentiation GO:0046661 64 0.011
sequestering of metal ion GO:0051238 9 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
cellular chemical homeostasis GO:0055082 247 0.010
regulation of transferase activity GO:0051338 123 0.010
regulation of anatomical structure morphogenesis GO:0022603 141 0.010
regulation of homeostatic process GO:0032844 101 0.010
regulation of membrane potential GO:0042391 110 0.010
sequestering of calcium ion GO:0051208 8 0.010
organic anion transport GO:0015711 132 0.010
negative regulation of rna metabolic process GO:0051253 123 0.010
blood vessel development GO:0001568 69 0.010
synaptic growth at neuromuscular junction GO:0051124 1 0.010
rho protein signal transduction GO:0007266 11 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.010
cellular response to nitrogen compound GO:1901699 210 0.010
regulation of cell growth GO:0001558 85 0.010
regulation of cell morphogenesis GO:0022604 77 0.010
cardiac chamber development GO:0003205 1 0.010
cilium morphogenesis GO:0060271 2 0.010
chemosensory behavior GO:0007635 2 0.010
cellular response to cytokine stimulus GO:0071345 127 0.010
cellular protein localization GO:0034613 122 0.010
ion homeostasis GO:0050801 212 0.010
positive regulation of transport GO:0051050 245 0.010
cellular macromolecule localization GO:0070727 122 0.010

Dusp18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
musculoskeletal system disease DOID:17 0 0.010