Rattus norvegicus

63 known processes

Dusp12

dual specificity phosphatase 12

(Aliases: GKAP)

Dusp12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of rna metabolic process GO:0051252 391 0.082
regulation of nucleic acid templated transcription GO:1903506 380 0.073
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.065
positive regulation of biosynthetic process GO:0009891 319 0.057
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.057
nucleic acid templated transcription GO:0097659 379 0.056
positive regulation of cellular biosynthetic process GO:0031328 295 0.053
rna biosynthetic process GO:0032774 380 0.051
cellular response to endogenous stimulus GO:0071495 377 0.050
intracellular signal transduction GO:0035556 314 0.048
Fly
regulation of transcription dna templated GO:0006355 374 0.046
protein phosphorylation GO:0006468 345 0.046
Fly
regulation of signal transduction GO:0009966 318 0.045
Fly
oxoacid metabolic process GO:0043436 290 0.044
regulation of rna biosynthetic process GO:2001141 381 0.044
cellular response to oxygen containing compound GO:1901701 386 0.043
organic acid metabolic process GO:0006082 292 0.043
single organism biosynthetic process GO:0044711 342 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.040
negative regulation of metabolic process GO:0009892 331 0.036
Fly
catabolic process GO:0009056 351 0.036
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.035
regulation of cellular component organization GO:0051128 368 0.034
macromolecule localization GO:0033036 252 0.034
positive regulation of nucleic acid templated transcription GO:1903508 197 0.034
regulation of multicellular organismal development GO:2000026 376 0.033
regulation of cell differentiation GO:0045595 320 0.033
reproductive process GO:0022414 372 0.032
positive regulation of multicellular organismal process GO:0051240 387 0.031
regulation of protein metabolic process GO:0051246 289 0.031
Fly
positive regulation of gene expression GO:0010628 244 0.031
rna metabolic process GO:0016070 406 0.031
positive regulation of rna biosynthetic process GO:1902680 197 0.030
response to nutrient levels GO:0031667 370 0.029
regulation of protein modification process GO:0031399 194 0.029
Fly
transcription dna templated GO:0006351 377 0.029
cellular component assembly GO:0022607 360 0.028
regulation of programmed cell death GO:0043067 341 0.028
anatomical structure morphogenesis GO:0009653 298 0.028
lipid metabolic process GO:0006629 283 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
positive regulation of rna metabolic process GO:0051254 203 0.026
programmed cell death GO:0012501 392 0.026
cellular component biogenesis GO:0044085 368 0.026
organic substance catabolic process GO:1901575 316 0.025
regulation of phosphorylation GO:0042325 248 0.025
aging GO:0007568 241 0.025
single organism intracellular transport GO:1902582 166 0.024
transmembrane transport GO:0055085 412 0.024
cellular catabolic process GO:0044248 295 0.024
inorganic ion transmembrane transport GO:0098660 229 0.024
intracellular transport GO:0046907 185 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.023
Fly
protein transport GO:0015031 132 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
organophosphate biosynthetic process GO:0090407 143 0.023
carboxylic acid metabolic process GO:0019752 289 0.023
cellular ketone metabolic process GO:0042180 51 0.023
amine metabolic process GO:0009308 38 0.023
macromolecular complex assembly GO:0065003 273 0.023
cell projection organization GO:0030030 302 0.023
negative regulation of gene expression GO:0010629 199 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
Fly
cellular amino acid metabolic process GO:0006520 107 0.022
muscle contraction GO:0006936 88 0.022
cellular response to stress GO:0033554 269 0.022
Fly
neuron differentiation GO:0030182 368 0.022
cellular amine metabolic process GO:0044106 38 0.022
regulation of apoptotic process GO:0042981 335 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.021
single organism reproductive process GO:0044702 297 0.021
organic acid biosynthetic process GO:0016053 83 0.021
carboxylic acid biosynthetic process GO:0046394 83 0.021
negative regulation of multicellular organismal process GO:0051241 203 0.021
small molecule biosynthetic process GO:0044283 124 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
positive regulation of transcription dna templated GO:0045893 197 0.021
response to metal ion GO:0010038 253 0.021
neuron projection development GO:0031175 273 0.020
transcription from rna polymerase ii promoter GO:0006366 252 0.020
metal ion transport GO:0030001 289 0.020
organelle organization GO:0006996 266 0.020
positive regulation of molecular function GO:0044093 230 0.020
chemical homeostasis GO:0048878 292 0.020
protein localization GO:0008104 191 0.020
negative regulation of cellular metabolic process GO:0031324 281 0.020
Fly
tissue development GO:0009888 252 0.019
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
reproductive structure development GO:0048608 128 0.019
positive regulation of cell death GO:0010942 184 0.019
lipid biosynthetic process GO:0008610 128 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.019
regulation of molecular function GO:0065009 398 0.019
cation transmembrane transport GO:0098655 263 0.019
establishment of protein localization GO:0045184 141 0.019
reproductive system development GO:0061458 128 0.019
regulation of catalytic activity GO:0050790 304 0.019
vesicle mediated transport GO:0016192 181 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
Fly
proteolysis GO:0006508 175 0.019
muscle system process GO:0003012 115 0.019
enzyme linked receptor protein signaling pathway GO:0007167 116 0.019
apoptotic process GO:0006915 381 0.018
positive regulation of developmental process GO:0051094 283 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
ion transmembrane transport GO:0034220 365 0.018
negative regulation of biosynthetic process GO:0009890 168 0.018
response to radiation GO:0009314 137 0.018
response to growth factor GO:0070848 189 0.018
developmental process involved in reproduction GO:0003006 159 0.018
organonitrogen compound biosynthetic process GO:1901566 167 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
multicellular organism reproduction GO:0032504 233 0.018
negative regulation of protein metabolic process GO:0051248 114 0.017
Fly
regulation of phosphate metabolic process GO:0019220 349 0.017
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
fatty acid metabolic process GO:0006631 99 0.017
cytoplasmic transport GO:0016482 115 0.017
reproduction GO:0000003 245 0.017
response to extracellular stimulus GO:0009991 380 0.017
regulation of ion transport GO:0043269 245 0.017
regulation of kinase activity GO:0043549 117 0.016
negative regulation of signaling GO:0023057 157 0.016
Fly
response to inorganic substance GO:0010035 377 0.016
positive regulation of cell development GO:0010720 176 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
protein complex assembly GO:0006461 263 0.016
regulation of protein kinase activity GO:0045859 105 0.016
Fly
response to estradiol GO:0032355 164 0.016
regulation of cell development GO:0060284 263 0.016
homeostatic process GO:0042592 331 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
regulation of membrane potential GO:0042391 110 0.015
regulation of synaptic transmission GO:0050804 141 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
cellular cation homeostasis GO:0030003 180 0.015
regulation of secretion GO:0051046 224 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
regulation of phosphorus metabolic process GO:0051174 349 0.015
negative regulation of molecular function GO:0044092 133 0.015
Fly
single organism organelle organization GO:1902589 180 0.015
response to toxic substance GO:0009636 133 0.015
gland development GO:0048732 155 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
anion transport GO:0006820 178 0.014
secretion GO:0046903 307 0.014
negative regulation of rna biosynthetic process GO:1902679 118 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
sex differentiation GO:0007548 113 0.014
monocarboxylic acid metabolic process GO:0032787 152 0.013
striated muscle contraction GO:0006941 44 0.013
response to hypoxia GO:0001666 231 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
sodium ion transport GO:0006814 82 0.013
positive regulation of protein modification process GO:0031401 142 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
male sex differentiation GO:0046661 64 0.013
metal ion homeostasis GO:0055065 186 0.013
membrane organization GO:0061024 94 0.013
cell cell signaling involved in cell fate commitment GO:0045168 2 0.013
protein complex biogenesis GO:0070271 263 0.013
cellular macromolecule localization GO:0070727 122 0.013
cellular lipid metabolic process GO:0044255 208 0.013
gonad development GO:0008406 104 0.013
positive regulation of transport GO:0051050 245 0.013
organophosphate metabolic process GO:0019637 370 0.013
regulation of system process GO:0044057 208 0.013
cellular response to hormone stimulus GO:0032870 247 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
Fly
regulation of cell projection organization GO:0031344 175 0.012
response to organophosphorus GO:0046683 102 0.012
organ formation GO:0048645 3 0.012
response to external biotic stimulus GO:0043207 221 0.012
regulation of nervous system development GO:0051960 264 0.012
kidney development GO:0001822 67 0.012
negative regulation of transport GO:0051051 136 0.012
protein complex subunit organization GO:0071822 302 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
regulation of transferase activity GO:0051338 123 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
Fly
ribose phosphate metabolic process GO:0019693 235 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
cellular response to metal ion GO:0071248 55 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
single organism catabolic process GO:0044712 283 0.012
regulation of ion transmembrane transport GO:0034765 121 0.012
purine nucleotide biosynthetic process GO:0006164 83 0.012
ion homeostasis GO:0050801 212 0.012
alcohol metabolic process GO:0006066 77 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
purine containing compound metabolic process GO:0072521 253 0.012
cation transport GO:0006812 382 0.012
male gamete generation GO:0048232 99 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
response to temperature stimulus GO:0009266 94 0.011
central nervous system development GO:0007417 311 0.011
development of primary sexual characteristics GO:0045137 107 0.011
lipid transport GO:0006869 61 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
regulation of catabolic process GO:0009894 113 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
negative regulation of cell communication GO:0010648 158 0.011
Fly
spermatogenesis GO:0007283 99 0.011
cellular homeostasis GO:0019725 252 0.011
aromatic amino acid family metabolic process GO:0009072 9 0.011
cell type specific apoptotic process GO:0097285 134 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
cellular component movement GO:0006928 248 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
response to lipopolysaccharide GO:0032496 191 0.011
response to oxidative stress GO:0006979 186 0.011
response to biotic stimulus GO:0009607 226 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
Fly
cellular ion homeostasis GO:0006873 184 0.011
regulation of anatomical structure size GO:0090066 135 0.011
ras protein signal transduction GO:0007265 29 0.011
epithelial cell differentiation GO:0030855 71 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
response to carbohydrate GO:0009743 183 0.011
nucleotide metabolic process GO:0009117 279 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
cyclic purine nucleotide metabolic process GO:0052652 62 0.011
cardiovascular system development GO:0072358 134 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
gamete generation GO:0007276 124 0.010
single organism cellular localization GO:1902580 102 0.010
heterocycle catabolic process GO:0046700 167 0.010
purine ribonucleotide biosynthetic process GO:0009152 81 0.010
negative regulation of signal transduction GO:0009968 83 0.010
Fly
lipid storage GO:0019915 1 0.010
urogenital system development GO:0001655 78 0.010
response to oxygen levels GO:0070482 265 0.010
glycosyl compound metabolic process GO:1901657 182 0.010
axis specification GO:0009798 4 0.010
positive regulation of signal transduction GO:0009967 175 0.010
regulation of g0 to g1 transition GO:0070316 3 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
bmp signaling pathway GO:0030509 4 0.010
actin filament based process GO:0030029 86 0.010

Dusp12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.014
myopathy DOID:423 0 0.011
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011