Rattus norvegicus

0 known processes

Higd1b

HIG1 hypoxia inducible domain family, member 1B

(Aliases: RGD1306907)

Higd1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to inorganic substance GO:0010035 377 0.139
tissue development GO:0009888 252 0.115
response to wounding GO:0009611 254 0.115
cellular component movement GO:0006928 248 0.095
regulation of cell proliferation GO:0042127 359 0.079
response to hexose GO:0009746 144 0.074
organic acid metabolic process GO:0006082 292 0.073
response to oxygen levels GO:0070482 265 0.066
response to oxidative stress GO:0006979 186 0.061
negative regulation of metabolic process GO:0009892 331 0.059
cellular response to oxygen containing compound GO:1901701 386 0.058
response to nutrient GO:0007584 248 0.056
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.055
homeostatic process GO:0042592 331 0.053
regulation of cellular component organization GO:0051128 368 0.053
nucleoside phosphate metabolic process GO:0006753 283 0.052
positive regulation of phosphate metabolic process GO:0045937 262 0.051
programmed cell death GO:0012501 392 0.051
response to estrogen GO:0043627 232 0.050
lipid metabolic process GO:0006629 283 0.050
apoptotic process GO:0006915 381 0.050
response to extracellular stimulus GO:0009991 380 0.049
catabolic process GO:0009056 351 0.049
cell motility GO:0048870 202 0.049
regulation of programmed cell death GO:0043067 341 0.048
oxoacid metabolic process GO:0043436 290 0.048
cellular response to stress GO:0033554 269 0.047
response to hypoxia GO:0001666 231 0.046
organic cyclic compound catabolic process GO:1901361 175 0.046
rna biosynthetic process GO:0032774 380 0.045
positive regulation of programmed cell death GO:0043068 157 0.044
regulation of apoptotic process GO:0042981 335 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.044
positive regulation of cell proliferation GO:0008284 249 0.044
positive regulation of phosphorus metabolic process GO:0010562 262 0.044
cellular component biogenesis GO:0044085 368 0.043
regulation of rna biosynthetic process GO:2001141 381 0.043
organophosphate metabolic process GO:0019637 370 0.042
response to glucocorticoid GO:0051384 223 0.042
cellular response to external stimulus GO:0071496 118 0.042
response to carbohydrate GO:0009743 183 0.042
intracellular signal transduction GO:0035556 314 0.041
response to nutrient levels GO:0031667 370 0.041
carboxylic acid metabolic process GO:0019752 289 0.040
positive regulation of response to stimulus GO:0048584 285 0.039
response to decreased oxygen levels GO:0036293 237 0.039
cellular catabolic process GO:0044248 295 0.039
negative regulation of macromolecule metabolic process GO:0010605 260 0.039
regulation of phosphate metabolic process GO:0019220 349 0.039
negative regulation of biosynthetic process GO:0009890 168 0.038
response to metal ion GO:0010038 253 0.037
nucleobase containing small molecule metabolic process GO:0055086 316 0.036
single organism catabolic process GO:0044712 283 0.036
carbohydrate derivative metabolic process GO:1901135 346 0.036
response to peptide GO:1901652 292 0.036
cellular lipid metabolic process GO:0044255 208 0.036
regulation of nucleic acid templated transcription GO:1903506 380 0.035
rna metabolic process GO:0016070 406 0.035
cellular chemical homeostasis GO:0055082 247 0.035
regulation of signal transduction GO:0009966 318 0.034
negative regulation of cell death GO:0060548 229 0.034
reproduction GO:0000003 245 0.033
negative regulation of cellular metabolic process GO:0031324 281 0.033
regeneration GO:0031099 163 0.033
neurological system process GO:0050877 219 0.033
positive regulation of biosynthetic process GO:0009891 319 0.032
regulation of multicellular organismal development GO:2000026 376 0.031
regulation of rna metabolic process GO:0051252 391 0.030
ribonucleotide metabolic process GO:0009259 231 0.030
response to corticosteroid GO:0031960 235 0.030
multicellular organismal reproductive process GO:0048609 233 0.030
response to glucose GO:0009749 136 0.029
regulation of catalytic activity GO:0050790 304 0.029
response to ketone GO:1901654 182 0.029
ion transmembrane transport GO:0034220 365 0.029
regulation of hormone levels GO:0010817 187 0.029
positive regulation of signaling GO:0023056 270 0.029
nucleic acid templated transcription GO:0097659 379 0.029
positive regulation of cell communication GO:0010647 271 0.028
positive regulation of rna biosynthetic process GO:1902680 197 0.028
limb morphogenesis GO:0035108 4 0.028
multi organism reproductive process GO:0044703 262 0.028
response to external biotic stimulus GO:0043207 221 0.027
organonitrogen compound catabolic process GO:1901565 179 0.027
proteolysis GO:0006508 175 0.027
reproductive process GO:0022414 372 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.026
peptidyl amino acid modification GO:0018193 126 0.026
regulation of cellular catabolic process GO:0031329 101 0.026
locomotion GO:0040011 237 0.026
multi multicellular organism process GO:0044706 138 0.026
response to monosaccharide GO:0034284 159 0.025
cellular amine metabolic process GO:0044106 38 0.025
female pregnancy GO:0007565 122 0.025
immune system process GO:0002376 204 0.025
transcription dna templated GO:0006351 377 0.025
response to molecule of bacterial origin GO:0002237 194 0.025
cation transmembrane transport GO:0098655 263 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
negative regulation of gene expression GO:0010629 199 0.025
response to growth factor GO:0070848 189 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
regulation of transcription dna templated GO:0006355 374 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
regulation of molecular function GO:0065009 398 0.024
ribonucleoside triphosphate catabolic process GO:0009203 122 0.024
central nervous system development GO:0007417 311 0.024
localization of cell GO:0051674 202 0.024
circulatory system process GO:0003013 183 0.024
cellular homeostasis GO:0019725 252 0.024
positive regulation of protein phosphorylation GO:0001934 135 0.024
cellular ketone metabolic process GO:0042180 51 0.024
nucleotide metabolic process GO:0009117 279 0.023
regulation of hydrolase activity GO:0051336 143 0.023
aging GO:0007568 241 0.023
ion homeostasis GO:0050801 212 0.023
organic substance catabolic process GO:1901575 316 0.023
neuron differentiation GO:0030182 368 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.023
positive regulation of intracellular signal transduction GO:1902533 138 0.023
negative regulation of protein metabolic process GO:0051248 114 0.023
blood circulation GO:0008015 183 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
regulation of phosphorus metabolic process GO:0051174 349 0.022
carbohydrate derivative catabolic process GO:1901136 147 0.022
purine containing compound metabolic process GO:0072521 253 0.022
single organism biosynthetic process GO:0044711 342 0.022
sodium ion transport GO:0006814 82 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
wound healing GO:0042060 122 0.022
regulation of ion transport GO:0043269 245 0.022
organelle organization GO:0006996 266 0.021
chemical homeostasis GO:0048878 292 0.021
nucleobase containing compound catabolic process GO:0034655 152 0.021
regulation of protein metabolic process GO:0051246 289 0.021
heterocycle catabolic process GO:0046700 167 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
negative regulation of rna metabolic process GO:0051253 123 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
amine metabolic process GO:0009308 38 0.021
protein complex assembly GO:0006461 263 0.021
brain development GO:0007420 247 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
response to reactive oxygen species GO:0000302 120 0.020
regulation of cellular component movement GO:0051270 150 0.020
cellular response to abiotic stimulus GO:0071214 85 0.020
appendage morphogenesis GO:0035107 4 0.020
transcription from rna polymerase ii promoter GO:0006366 252 0.020
positive regulation of signal transduction GO:0009967 175 0.020
multicellular organism reproduction GO:0032504 233 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.019
fatty acid metabolic process GO:0006631 99 0.019
cell migration GO:0016477 197 0.019
cellular response to organic cyclic compound GO:0071407 202 0.019
nucleoside phosphate catabolic process GO:1901292 140 0.019
response to lipopolysaccharide GO:0032496 191 0.019
g protein coupled receptor signaling pathway GO:0007186 242 0.019
single organism reproductive process GO:0044702 297 0.019
response to biotic stimulus GO:0009607 226 0.019
monovalent inorganic cation transport GO:0015672 172 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
cation transport GO:0006812 382 0.018
regulation of system process GO:0044057 208 0.018
ribonucleoside triphosphate metabolic process GO:0009199 141 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
defense response GO:0006952 194 0.017
metal ion transport GO:0030001 289 0.017
regulation of secretion by cell GO:1903530 208 0.017
positive regulation of gene expression GO:0010628 244 0.017
head development GO:0060322 247 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
positive regulation of cell death GO:0010942 184 0.017
cell growth GO:0016049 104 0.017
gamete generation GO:0007276 124 0.017
negative regulation of signaling GO:0023057 157 0.017
regulation of secretion GO:0051046 224 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
purine nucleotide catabolic process GO:0006195 136 0.017
transmembrane transport GO:0055085 412 0.017
cellular nitrogen compound catabolic process GO:0044270 163 0.017
aromatic compound catabolic process GO:0019439 168 0.017
positive regulation of molecular function GO:0044093 230 0.017
positive regulation of catabolic process GO:0009896 78 0.017
response to estradiol GO:0032355 164 0.017
growth GO:0040007 165 0.017
regulation of muscle system process GO:0090257 79 0.016
nucleotide catabolic process GO:0009166 139 0.016
epithelium development GO:0060429 96 0.016
monocarboxylic acid metabolic process GO:0032787 152 0.016
nitrogen compound transport GO:0071705 229 0.016
negative regulation of molecular function GO:0044092 133 0.016
negative regulation of cell communication GO:0010648 158 0.016
organophosphate catabolic process GO:0046434 148 0.016
positive regulation of nervous system development GO:0051962 178 0.016
neuron projection development GO:0031175 273 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
regulation of response to external stimulus GO:0032101 106 0.016
enzyme linked receptor protein signaling pathway GO:0007167 116 0.016
response to toxic substance GO:0009636 133 0.016
muscle system process GO:0003012 115 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.016
cellular component assembly GO:0022607 360 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.015
organ regeneration GO:0031100 101 0.015
nucleoside catabolic process GO:0009164 126 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
nucleoside metabolic process GO:0009116 179 0.015
regulation of peptide transport GO:0090087 87 0.015
response to other organism GO:0051707 220 0.015
signal transduction by phosphorylation GO:0023014 144 0.015
cytoskeleton organization GO:0007010 111 0.015
macromolecular complex subunit organization GO:0043933 339 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
reproductive system development GO:0061458 128 0.015
regulation of metal ion transport GO:0010959 118 0.015
urogenital system development GO:0001655 78 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
secretion GO:0046903 307 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
regulation of neurogenesis GO:0050767 247 0.014
sensory organ development GO:0007423 74 0.014
regulation of cellular component biogenesis GO:0044087 86 0.014
regulation of cell growth GO:0001558 85 0.014
nucleoside triphosphate catabolic process GO:0009143 123 0.014
nucleoside triphosphate metabolic process GO:0009141 144 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
single organism organelle organization GO:1902589 180 0.014
positive regulation of developmental process GO:0051094 283 0.014
kidney development GO:0001822 67 0.014
regulation of cell projection organization GO:0031344 175 0.014
regulation of catabolic process GO:0009894 113 0.014
purine nucleoside catabolic process GO:0006152 124 0.014
peptide secretion GO:0002790 86 0.014
negative regulation of transport GO:0051051 136 0.014
ras protein signal transduction GO:0007265 29 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
regulation of cell differentiation GO:0045595 320 0.014
rhythmic process GO:0048511 156 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
neuronal action potential GO:0019228 35 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
cellular ion homeostasis GO:0006873 184 0.014
calcium ion homeostasis GO:0055074 162 0.014
metal ion homeostasis GO:0055065 186 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
regulation of cellular localization GO:0060341 263 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
protein complex biogenesis GO:0070271 263 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
ossification GO:0001503 70 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
multicellular organism growth GO:0035264 1 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
response to acid chemical GO:0001101 222 0.013
cellular response to endogenous stimulus GO:0071495 377 0.013
oxidation reduction process GO:0055114 304 0.013
cellular cation homeostasis GO:0030003 180 0.013
cellular response to oxygen levels GO:0071453 60 0.013
action potential GO:0001508 54 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
positive regulation of cellular biosynthetic process GO:0031328 295 0.013
organic anion transport GO:0015711 132 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
nephric duct development GO:0072176 1 0.013
regulation of cell development GO:0060284 263 0.013
terpenoid metabolic process GO:0006721 37 0.013
response to ethanol GO:0045471 162 0.013
Fly
ribonucleoside metabolic process GO:0009119 174 0.013
dna metabolic process GO:0006259 96 0.013
epithelial cell differentiation GO:0030855 71 0.013
peptide transport GO:0015833 97 0.013
cellular response to hypoxia GO:0071456 51 0.013
cellular response to alcohol GO:0097306 87 0.012
response to purine containing compound GO:0014074 126 0.012
regulation of hormone secretion GO:0046883 106 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
retina morphogenesis in camera type eye GO:0060042 1 0.012
regulation of membrane potential GO:0042391 110 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
positive regulation of transport GO:0051050 245 0.012
gland development GO:0048732 155 0.012
protein phosphorylation GO:0006468 345 0.012
carbohydrate homeostasis GO:0033500 75 0.012
cellular response to peptide GO:1901653 133 0.012
macromolecular complex assembly GO:0065003 273 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
regulation of anatomical structure size GO:0090066 135 0.012
purine containing compound catabolic process GO:0072523 138 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
regulation of growth GO:0040008 105 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
spermatogenesis GO:0007283 99 0.012
amide transport GO:0042886 105 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
response to transition metal nanoparticle GO:1990267 122 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
response to vitamin GO:0033273 131 0.011
regulation of response to stress GO:0080134 126 0.011
embryonic appendage morphogenesis GO:0035113 4 0.011
male gamete generation GO:0048232 99 0.011
sexual reproduction GO:0019953 148 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
glucose homeostasis GO:0042593 75 0.011
eye morphogenesis GO:0048592 4 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
regulation of neuron projection development GO:0010975 161 0.011
response to bacterium GO:0009617 200 0.011
peptide hormone secretion GO:0030072 84 0.011
vasoconstriction GO:0042310 54 0.011
cellular component morphogenesis GO:0032989 155 0.011
regulation of protein modification process GO:0031399 194 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
rho protein signal transduction GO:0007266 11 0.011
axis specification GO:0009798 4 0.011
hepaticobiliary system development GO:0061008 90 0.011
positive regulation of locomotion GO:0040017 102 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
macromolecule localization GO:0033036 252 0.011
secretion by cell GO:0032940 248 0.011
response to mechanical stimulus GO:0009612 134 0.011
regulation of blood pressure GO:0008217 83 0.011
cytoplasmic transport GO:0016482 115 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
regulation of organelle organization GO:0033043 80 0.011
positive regulation of transferase activity GO:0051347 81 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
cellular response to monosaccharide stimulus GO:0071326 67 0.011
positive regulation of peptide secretion GO:0002793 52 0.011
cellular response to lipid GO:0071396 201 0.011
cellular response to reactive oxygen species GO:0034614 55 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
positive regulation of protein metabolic process GO:0051247 178 0.010
regulation of transferase activity GO:0051338 123 0.010
positive regulation of response to external stimulus GO:0032103 51 0.010
gastrulation GO:0007369 2 0.010
lipid catabolic process GO:0016042 46 0.010
protein complex subunit organization GO:0071822 302 0.010
regulation of cell motility GO:2000145 131 0.010
heart development GO:0007507 72 0.010
cation homeostasis GO:0055080 195 0.010
small molecule catabolic process GO:0044282 59 0.010
positive regulation of cellular catabolic process GO:0031331 71 0.010
muscle structure development GO:0061061 87 0.010
cell projection organization GO:0030030 302 0.010
multicellular organismal signaling GO:0035637 44 0.010
regulation of peptide secretion GO:0002791 82 0.010

Higd1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
sensory system disease DOID:0050155 0 0.019
hypertension DOID:10763 0 0.010
artery disease DOID:0050828 0 0.010
vascular disease DOID:178 0 0.010
essential hypertension DOID:10825 0 0.010
cardiovascular system disease DOID:1287 0 0.010