Rattus norvegicus

0 known processes

Blnk

B-cell linker

(Aliases: MGC112831)

Blnk biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
programmed cell death GO:0012501 392 0.111
regulation of programmed cell death GO:0043067 341 0.105
homeostatic process GO:0042592 331 0.101
cellular amino acid metabolic process GO:0006520 107 0.098
regulation of cell proliferation GO:0042127 359 0.089
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.085
immune system process GO:0002376 204 0.083
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.077
nucleotide metabolic process GO:0009117 279 0.076
nucleobase containing small molecule metabolic process GO:0055086 316 0.074
regulation of secretion by cell GO:1903530 208 0.073
apoptotic process GO:0006915 381 0.073
nucleoside phosphate metabolic process GO:0006753 283 0.072
intracellular signal transduction GO:0035556 314 0.071
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.070
regulation of protein metabolic process GO:0051246 289 0.070
regulation of apoptotic process GO:0042981 335 0.065
metal ion transport GO:0030001 289 0.065
regulation of catalytic activity GO:0050790 304 0.064
carboxylic acid metabolic process GO:0019752 289 0.061
protein complex biogenesis GO:0070271 263 0.061
response to wounding GO:0009611 254 0.060
regulation of molecular function GO:0065009 398 0.060
positive regulation of signaling GO:0023056 270 0.059
Human
regulation of cellular amine metabolic process GO:0033238 8 0.057
positive regulation of programmed cell death GO:0043068 157 0.057
oxoacid metabolic process GO:0043436 290 0.056
regulation of phosphorus metabolic process GO:0051174 349 0.055
regulation of multicellular organismal development GO:2000026 376 0.054
regulation of signal transduction GO:0009966 318 0.052
Human
negative regulation of cell death GO:0060548 229 0.052
positive regulation of phosphorylation GO:0042327 177 0.051
organic acid metabolic process GO:0006082 292 0.051
catabolic process GO:0009056 351 0.050
nucleic acid templated transcription GO:0097659 379 0.049
cellular response to endogenous stimulus GO:0071495 377 0.048
positive regulation of response to stimulus GO:0048584 285 0.048
Human
regulation of phosphorylation GO:0042325 248 0.048
purine ribonucleotide metabolic process GO:0009150 227 0.048
regulation of cellular amino acid metabolic process GO:0006521 2 0.047
chemical homeostasis GO:0048878 292 0.047
single organism biosynthetic process GO:0044711 342 0.047
protein phosphorylation GO:0006468 345 0.046
positive regulation of cell death GO:0010942 184 0.045
ribonucleoside triphosphate catabolic process GO:0009203 122 0.044
macromolecular complex assembly GO:0065003 273 0.044
negative regulation of immune system process GO:0002683 39 0.044
cellular ketone metabolic process GO:0042180 51 0.043
regulation of rna biosynthetic process GO:2001141 381 0.043
rna biosynthetic process GO:0032774 380 0.043
carbohydrate derivative metabolic process GO:1901135 346 0.041
regulation of cellular ketone metabolic process GO:0010565 27 0.041
positive regulation of molecular function GO:0044093 230 0.041
positive regulation of cell proliferation GO:0008284 249 0.041
regulation of phosphate metabolic process GO:0019220 349 0.041
ribonucleotide metabolic process GO:0009259 231 0.041
regulation of cellular localization GO:0060341 263 0.040
negative regulation of innate immune response GO:0045824 4 0.040
positive regulation of cellular protein metabolic process GO:0032270 167 0.040
gland development GO:0048732 155 0.039
positive regulation of phosphate metabolic process GO:0045937 262 0.039
leukocyte activation GO:0045321 76 0.039
cellular amine metabolic process GO:0044106 38 0.039
central nervous system development GO:0007417 311 0.039
regulation of protein phosphorylation GO:0001932 183 0.038
defense response GO:0006952 194 0.038
ribose phosphate metabolic process GO:0019693 235 0.038
cell activation GO:0001775 97 0.037
negative regulation of response to stimulus GO:0048585 155 0.037
purine containing compound metabolic process GO:0072521 253 0.037
ion homeostasis GO:0050801 212 0.037
glycosyl compound metabolic process GO:1901657 182 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.037
cellular response to stress GO:0033554 269 0.037
transcription dna templated GO:0006351 377 0.037
nucleotide catabolic process GO:0009166 139 0.036
negative regulation of gene expression GO:0010629 199 0.035
cell cell signaling GO:0007267 335 0.035
divalent metal ion transport GO:0070838 132 0.035
reproductive process GO:0022414 372 0.035
positive regulation of multicellular organismal process GO:0051240 387 0.034
regulation of rna metabolic process GO:0051252 391 0.034
positive regulation of apoptotic process GO:0043065 154 0.034
positive regulation of secretion by cell GO:1903532 128 0.034
positive regulation of protein phosphorylation GO:0001934 135 0.034
ribonucleotide catabolic process GO:0009261 136 0.034
positive regulation of catalytic activity GO:0043085 184 0.034
negative regulation of programmed cell death GO:0043069 183 0.034
amine metabolic process GO:0009308 38 0.033
regulation of hydrolase activity GO:0051336 143 0.033
response to oxidative stress GO:0006979 186 0.033
regulation of protein modification process GO:0031399 194 0.033
regulation of immune response GO:0050776 55 0.033
immune response GO:0006955 104 0.033
cellular response to oxygen containing compound GO:1901701 386 0.031
purine nucleoside catabolic process GO:0006152 124 0.031
cellular component biogenesis GO:0044085 368 0.031
response to acid chemical GO:0001101 222 0.031
purine containing compound catabolic process GO:0072523 138 0.030
positive regulation of protein metabolic process GO:0051247 178 0.030
organic cyclic compound catabolic process GO:1901361 175 0.030
regulation of transcription dna templated GO:0006355 374 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
nucleobase containing compound catabolic process GO:0034655 152 0.029
ribonucleoside triphosphate metabolic process GO:0009199 141 0.029
response to extracellular stimulus GO:0009991 380 0.029
negative regulation of metabolic process GO:0009892 331 0.029
response to inorganic substance GO:0010035 377 0.029
divalent inorganic cation transport GO:0072511 134 0.029
organic substance catabolic process GO:1901575 316 0.029
mapk cascade GO:0000165 140 0.029
positive regulation of cell communication GO:0010647 271 0.029
Human
endocytosis GO:0006897 84 0.029
organonitrogen compound catabolic process GO:1901565 179 0.028
purine nucleoside metabolic process GO:0042278 169 0.028
nucleoside catabolic process GO:0009164 126 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.028
locomotion GO:0040011 237 0.028
single organism catabolic process GO:0044712 283 0.028
organophosphate metabolic process GO:0019637 370 0.028
nucleoside phosphate catabolic process GO:1901292 140 0.028
actin filament based process GO:0030029 86 0.028
calcium ion transport GO:0006816 131 0.027
purine nucleoside triphosphate metabolic process GO:0009144 141 0.027
aromatic compound catabolic process GO:0019439 168 0.027
divalent inorganic cation homeostasis GO:0072507 165 0.027
cellular component assembly GO:0022607 360 0.027
nucleoside triphosphate metabolic process GO:0009141 144 0.027
monocarboxylic acid metabolic process GO:0032787 152 0.027
neuron development GO:0048666 286 0.027
single organism reproductive process GO:0044702 297 0.027
metal ion homeostasis GO:0055065 186 0.027
g protein coupled receptor signaling pathway GO:0007186 242 0.027
cellular homeostasis GO:0019725 252 0.027
signal transduction by phosphorylation GO:0023014 144 0.026
purine ribonucleotide catabolic process GO:0009154 136 0.026
purine nucleoside triphosphate catabolic process GO:0009146 122 0.026
neuron projection morphogenesis GO:0048812 122 0.026
purine ribonucleoside catabolic process GO:0046130 124 0.026
cellular response to growth factor stimulus GO:0071363 162 0.026
regulation of response to stress GO:0080134 126 0.026
macromolecule localization GO:0033036 252 0.025
nucleoside metabolic process GO:0009116 179 0.025
regeneration GO:0031099 163 0.025
ribonucleoside metabolic process GO:0009119 174 0.025
protein transport GO:0015031 132 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
response to bacterium GO:0009617 200 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
cation transport GO:0006812 382 0.025
regulation of secretion GO:0051046 224 0.025
single organism organelle organization GO:1902589 180 0.025
positive regulation of developmental process GO:0051094 283 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
rna metabolic process GO:0016070 406 0.024
regulation of immune system process GO:0002682 123 0.024
purine ribonucleoside metabolic process GO:0046128 168 0.024
positive regulation of protein modification process GO:0031401 142 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
carbohydrate derivative catabolic process GO:1901136 147 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
cellular ion homeostasis GO:0006873 184 0.024
secretion by cell GO:0032940 248 0.024
rhythmic process GO:0048511 156 0.023
regulation of cell differentiation GO:0045595 320 0.023
regulation of ion transport GO:0043269 245 0.023
regulation of nucleic acid templated transcription GO:1903506 380 0.023
lipid metabolic process GO:0006629 283 0.023
intracellular transport GO:0046907 185 0.023
ribonucleoside catabolic process GO:0042454 126 0.023
regulation of hormone levels GO:0010817 187 0.023
positive regulation of signal transduction GO:0009967 175 0.023
Human
signal release GO:0023061 145 0.022
cellular component movement GO:0006928 248 0.022
response to nutrient levels GO:0031667 370 0.022
regulation of protein kinase activity GO:0045859 105 0.022
positive regulation of gene expression GO:0010628 244 0.022
immune effector process GO:0002252 53 0.022
transmembrane transport GO:0055085 412 0.022
cellular nitrogen compound catabolic process GO:0044270 163 0.022
heterocycle catabolic process GO:0046700 167 0.022
cellular chemical homeostasis GO:0055082 247 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
growth GO:0040007 165 0.021
organophosphate catabolic process GO:0046434 148 0.021
regulation of neurogenesis GO:0050767 247 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
cell type specific apoptotic process GO:0097285 134 0.021
positive regulation of transport GO:0051050 245 0.021
positive regulation of immune response GO:0050778 42 0.021
localization of cell GO:0051674 202 0.021
cation homeostasis GO:0055080 195 0.021
purine nucleotide catabolic process GO:0006195 136 0.020
glycosyl compound catabolic process GO:1901658 126 0.020
cellular response to external stimulus GO:0071496 118 0.020
neuron differentiation GO:0030182 368 0.020
regulation of nervous system development GO:0051960 264 0.020
negative regulation of leukocyte mediated immunity GO:0002704 6 0.020
regulation of hormone secretion GO:0046883 106 0.020
positive regulation of intracellular signal transduction GO:1902533 138 0.020
neuron projection development GO:0031175 273 0.020
antigen receptor mediated signaling pathway GO:0050851 1 0.020
single organism intracellular transport GO:1902582 166 0.020
immune response regulating signaling pathway GO:0002764 19 0.019
peptidyl tyrosine modification GO:0018212 72 0.019
response to external biotic stimulus GO:0043207 221 0.019
response to reactive oxygen species GO:0000302 120 0.019
regulation of nucleotide metabolic process GO:0006140 117 0.019
negative regulation of molecular function GO:0044092 133 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
regulation of kinase activity GO:0043549 117 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
regulation of gtpase activity GO:0043087 57 0.019
cellular lipid metabolic process GO:0044255 208 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
cytoskeleton organization GO:0007010 111 0.018
multicellular organism reproduction GO:0032504 233 0.018
cellular cation homeostasis GO:0030003 180 0.018
regulation of cellular component organization GO:0051128 368 0.018
nitrogen compound transport GO:0071705 229 0.018
peptidyl amino acid modification GO:0018193 126 0.018
multi organism reproductive process GO:0044703 262 0.018
developmental growth GO:0048589 100 0.018
cytoplasmic transport GO:0016482 115 0.018
regulation of cell development GO:0060284 263 0.018
guanosine containing compound catabolic process GO:1901069 71 0.018
regulation of innate immune response GO:0045088 15 0.018
regulation of mapk cascade GO:0043408 116 0.018
aging GO:0007568 241 0.018
protein complex assembly GO:0006461 263 0.018
positive regulation of nucleotide metabolic process GO:0045981 91 0.017
fatty acid metabolic process GO:0006631 99 0.017
positive regulation of gtpase activity GO:0043547 47 0.017
positive regulation of secretion GO:0051047 140 0.017
hormone secretion GO:0046879 115 0.017
carboxylic acid biosynthetic process GO:0046394 83 0.017
response to estrogen GO:0043627 232 0.017
axis specification GO:0009798 4 0.017
reproduction GO:0000003 245 0.017
oxidation reduction process GO:0055114 304 0.017
response to peptide hormone GO:0043434 278 0.017
cellular catabolic process GO:0044248 295 0.017
negative regulation of cell communication GO:0010648 158 0.017
organelle organization GO:0006996 266 0.017
vesicle mediated transport GO:0016192 181 0.017
proteolysis GO:0006508 175 0.017
calcium ion homeostasis GO:0055074 162 0.017
immunoglobulin mediated immune response GO:0016064 4 0.017
anterior posterior pattern specification GO:0009952 1 0.017
response to biotic stimulus GO:0009607 226 0.017
regulation of tolerance induction to nonself antigen GO:0002655 1 0.017
cell adhesion GO:0007155 110 0.017
cell projection organization GO:0030030 302 0.017
regulation of immune effector process GO:0002697 32 0.017
ras protein signal transduction GO:0007265 29 0.017
negative regulation of protein metabolic process GO:0051248 114 0.017
response to metal ion GO:0010038 253 0.016
regulation of homeostatic process GO:0032844 101 0.016
protein oligomerization GO:0051259 191 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.016
guanosine containing compound metabolic process GO:1901068 74 0.016
cell part morphogenesis GO:0032990 123 0.016
protein localization GO:0008104 191 0.016
cell killing GO:0001906 13 0.016
inflammatory response GO:0006954 150 0.016
negative regulation of signaling GO:0023057 157 0.016
lymphocyte activation GO:0046649 43 0.016
transmission of nerve impulse GO:0019226 42 0.016
cognition GO:0050890 92 0.016
regulation of catabolic process GO:0009894 113 0.015
sequestering of calcium ion GO:0051208 8 0.015
nucleoside monophosphate metabolic process GO:0009123 93 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
negative regulation of catalytic activity GO:0043086 103 0.015
regulation of purine nucleotide catabolic process GO:0033121 65 0.015
regulation of metal ion transport GO:0010959 118 0.015
positive regulation of mapk cascade GO:0043410 92 0.015
regulation of neuron apoptotic process GO:0043523 83 0.015
regulation of gtp catabolic process GO:0033124 58 0.015
regulation of anatomical structure size GO:0090066 135 0.015
developmental process involved in reproduction GO:0003006 159 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
b cell differentiation GO:0030183 2 0.015
response to other organism GO:0051707 220 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
response to hypoxia GO:0001666 231 0.015
negative regulation of transport GO:0051051 136 0.014
response to decreased oxygen levels GO:0036293 237 0.014
neurological system process GO:0050877 219 0.014
response to insulin GO:0032868 133 0.014
muscle system process GO:0003012 115 0.014
regulation of system process GO:0044057 208 0.014
gtp catabolic process GO:0006184 71 0.014
response to oxygen levels GO:0070482 265 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
regulation of small gtpase mediated signal transduction GO:0051056 48 0.014
small molecule biosynthetic process GO:0044283 124 0.014
leukocyte mediated immunity GO:0002443 28 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
cellular macromolecule localization GO:0070727 122 0.014
gastrulation GO:0007369 2 0.014
embryonic pattern specification GO:0009880 1 0.014
establishment of protein localization GO:0045184 141 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
response to nutrient GO:0007584 248 0.014
dna metabolic process GO:0006259 96 0.014
regulation of membrane potential GO:0042391 110 0.014
regulation of protein localization GO:0032880 81 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
synaptic transmission GO:0007268 235 0.014
tissue development GO:0009888 252 0.014
sequestering of metal ion GO:0051238 9 0.013
negative regulation of cellular metabolic process GO:0031324 281 0.013
regulation of defense response GO:0031347 68 0.013
response to ketone GO:1901654 182 0.013
regulation of neuron death GO:1901214 115 0.013
regulation of mononuclear cell proliferation GO:0032944 26 0.013
eye morphogenesis GO:0048592 4 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
amide transport GO:0042886 105 0.013
carbohydrate metabolic process GO:0005975 130 0.013
response to carbohydrate GO:0009743 183 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.013
nucleoside triphosphate catabolic process GO:0009143 123 0.013
regulation of body fluid levels GO:0050878 90 0.013
hormone transport GO:0009914 121 0.013
regulation of growth GO:0040008 105 0.013
brain development GO:0007420 247 0.013
negative regulation of phosphate metabolic process GO:0045936 80 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
secretion GO:0046903 307 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
regulation of leukocyte activation GO:0002694 45 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
response to hexose GO:0009746 144 0.012
negative regulation of secretion GO:0051048 82 0.012
protein maturation GO:0051604 68 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
positive regulation of nucleoside metabolic process GO:0045979 55 0.012
positive regulation of protein kinase activity GO:0045860 73 0.012
enzyme linked receptor protein signaling pathway GO:0007167 116 0.012
leukocyte mediated cytotoxicity GO:0001909 10 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
reproductive system development GO:0061458 128 0.012
gtp metabolic process GO:0046039 72 0.012
regulation of nucleotide catabolic process GO:0030811 65 0.012
anion transport GO:0006820 178 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
negative regulation of homeostatic process GO:0032845 47 0.012
head development GO:0060322 247 0.012
response to hydrogen peroxide GO:0042542 89 0.012
negative regulation of signal transduction GO:0009968 83 0.012
regulation of peptidase activity GO:0052547 55 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
response to peptide GO:1901652 292 0.012
protein complex subunit organization GO:0071822 302 0.012
regulation of nucleoside metabolic process GO:0009118 66 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
neuronal action potential GO:0019228 35 0.012
maintenance of location GO:0051235 17 0.012
negative regulation of cell killing GO:0031342 5 0.012
learning or memory GO:0007611 90 0.012
coagulation GO:0050817 28 0.011
protein heterooligomerization GO:0051291 89 0.011
intracellular protein transport GO:0006886 79 0.011
sensory organ development GO:0007423 74 0.011
cell morphogenesis GO:0000902 142 0.011
axon development GO:0061564 96 0.011
response to cytokine GO:0034097 215 0.011
hematopoietic progenitor cell differentiation GO:0002244 2 0.011
peptide transport GO:0015833 97 0.011
single organism behavior GO:0044708 130 0.011
regulation of lymphocyte activation GO:0051249 34 0.011
cellular component morphogenesis GO:0032989 155 0.011
hepaticobiliary system development GO:0061008 90 0.011
positive regulation of catabolic process GO:0009896 78 0.011
negative regulation of immune effector process GO:0002698 12 0.011
rho protein signal transduction GO:0007266 11 0.011
ion transmembrane transport GO:0034220 365 0.011
positive regulation of cell development GO:0010720 176 0.011
sex differentiation GO:0007548 113 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
response to glucose GO:0009749 136 0.011
regulation of cell projection organization GO:0031344 175 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
response to monosaccharide GO:0034284 159 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.010
dephosphorylation GO:0016311 98 0.010
multicellular organism growth GO:0035264 1 0.010
cell migration GO:0016477 197 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
negative regulation of defense response GO:0031348 19 0.010
negative regulation of cellular amine metabolic process GO:0033239 3 0.010
regulation of leukocyte proliferation GO:0070663 26 0.010
positive regulation of kinase activity GO:0033674 77 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
regulation of transferase activity GO:0051338 123 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.010
activation of protein kinase activity GO:0032147 47 0.010
female pregnancy GO:0007565 122 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
unsaturated fatty acid metabolic process GO:0033559 39 0.010
regulation of ion homeostasis GO:2000021 63 0.010
innate immune response GO:0045087 35 0.010
response to radiation GO:0009314 137 0.010
cellular macromolecular complex assembly GO:0034622 58 0.010
reproductive structure development GO:0048608 128 0.010
positive regulation of gtp catabolic process GO:0033126 48 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
positive regulation of nervous system development GO:0051962 178 0.010

Blnk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
Human
nervous system disease DOID:863 0 0.016
sensory system disease DOID:0050155 0 0.010