Rattus norvegicus

0 known processes

Isg20

interferon stimulated exonuclease gene 20

(Aliases: MGC105645)

Isg20 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macromolecule localization GO:0033036 252 0.088
cell cell signaling GO:0007267 335 0.082
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.071
regulation of nucleic acid templated transcription GO:1903506 380 0.068
regulation of rna biosynthetic process GO:2001141 381 0.067
rna metabolic process GO:0016070 406 0.063
negative regulation of cell death GO:0060548 229 0.063
regulation of protein metabolic process GO:0051246 289 0.060
response to wounding GO:0009611 254 0.060
regulation of molecular function GO:0065009 398 0.059
cellular homeostasis GO:0019725 252 0.057
cellular ion homeostasis GO:0006873 184 0.055
apoptotic process GO:0006915 381 0.054
negative regulation of programmed cell death GO:0043069 183 0.053
regulation of programmed cell death GO:0043067 341 0.052
positive regulation of catalytic activity GO:0043085 184 0.052
protein phosphorylation GO:0006468 345 0.050
nucleobase containing small molecule metabolic process GO:0055086 316 0.050
central nervous system development GO:0007417 311 0.050
negative regulation of cell communication GO:0010648 158 0.050
negative regulation of cellular metabolic process GO:0031324 281 0.049
secretion GO:0046903 307 0.049
neuron differentiation GO:0030182 368 0.048
rna biosynthetic process GO:0032774 380 0.048
regulation of transcription dna templated GO:0006355 374 0.048
response to metal ion GO:0010038 253 0.047
nitrogen compound transport GO:0071705 229 0.047
organophosphate metabolic process GO:0019637 370 0.046
regulation of cell proliferation GO:0042127 359 0.046
positive regulation of developmental process GO:0051094 283 0.045
regulation of rna metabolic process GO:0051252 391 0.044
cellular response to stress GO:0033554 269 0.044
regulation of cellular component organization GO:0051128 368 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.043
nucleoside phosphate metabolic process GO:0006753 283 0.043
sensory perception GO:0007600 101 0.042
transcription dna templated GO:0006351 377 0.042
cellular response to endogenous stimulus GO:0071495 377 0.041
secretion by cell GO:0032940 248 0.041
negative regulation of gene expression GO:0010629 199 0.041
regulation of cell differentiation GO:0045595 320 0.041
programmed cell death GO:0012501 392 0.041
cellular divalent inorganic cation homeostasis GO:0072503 162 0.041
positive regulation of cell proliferation GO:0008284 249 0.040
cellular macromolecule localization GO:0070727 122 0.040
regulation of cellular localization GO:0060341 263 0.040
cellular cation homeostasis GO:0030003 180 0.040
negative regulation of macromolecule metabolic process GO:0010605 260 0.039
intracellular signal transduction GO:0035556 314 0.038
regulation of signal transduction GO:0009966 318 0.038
immune response GO:0006955 104 0.038
response to inorganic substance GO:0010035 377 0.038
cation transport GO:0006812 382 0.037
negative regulation of metabolic process GO:0009892 331 0.037
homeostatic process GO:0042592 331 0.037
regulation of apoptotic process GO:0042981 335 0.037
chemical homeostasis GO:0048878 292 0.036
response to oxidative stress GO:0006979 186 0.036
regulation of phosphorylation GO:0042325 248 0.035
neurological system process GO:0050877 219 0.035
signal transduction by phosphorylation GO:0023014 144 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.035
cell projection organization GO:0030030 302 0.034
regulation of catalytic activity GO:0050790 304 0.034
positive regulation of cellular component organization GO:0051130 200 0.034
response to hypoxia GO:0001666 231 0.033
reproduction GO:0000003 245 0.033
negative regulation of apoptotic process GO:0043066 181 0.033
regulation of phosphorus metabolic process GO:0051174 349 0.033
regulation of system process GO:0044057 208 0.033
positive regulation of biosynthetic process GO:0009891 319 0.032
cellular chemical homeostasis GO:0055082 247 0.032
cellular response to oxygen containing compound GO:1901701 386 0.032
positive regulation of cellular biosynthetic process GO:0031328 295 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.032
response to cytokine GO:0034097 215 0.032
negative regulation of biosynthetic process GO:0009890 168 0.031
regulation of cell development GO:0060284 263 0.031
cellular amino acid metabolic process GO:0006520 107 0.031
organelle organization GO:0006996 266 0.031
organic acid metabolic process GO:0006082 292 0.030
purine containing compound metabolic process GO:0072521 253 0.030
regulation of cellular protein metabolic process GO:0032268 267 0.029
response to growth factor GO:0070848 189 0.029
neuron development GO:0048666 286 0.029
carboxylic acid metabolic process GO:0019752 289 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.029
cellular component biogenesis GO:0044085 368 0.028
response to temperature stimulus GO:0009266 94 0.028
reproductive process GO:0022414 372 0.028
response to corticosteroid GO:0031960 235 0.028
nucleotide metabolic process GO:0009117 279 0.028
negative regulation of signaling GO:0023057 157 0.028
response to nutrient levels GO:0031667 370 0.028
protein complex biogenesis GO:0070271 263 0.028
response to oxygen levels GO:0070482 265 0.028
single organism intracellular transport GO:1902582 166 0.028
single organism catabolic process GO:0044712 283 0.028
brain development GO:0007420 247 0.027
positive regulation of phosphate metabolic process GO:0045937 262 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.027
positive regulation of cell differentiation GO:0045597 217 0.027
single organism biosynthetic process GO:0044711 342 0.027
regulation of transferase activity GO:0051338 123 0.027
nucleic acid templated transcription GO:0097659 379 0.027
aging GO:0007568 241 0.027
positive regulation of cellular protein metabolic process GO:0032270 167 0.026
negative regulation of response to stimulus GO:0048585 155 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.026
ion homeostasis GO:0050801 212 0.026
growth GO:0040007 165 0.026
neuron projection development GO:0031175 273 0.026
cellular component assembly GO:0022607 360 0.026
negative regulation of transport GO:0051051 136 0.025
macromolecular complex assembly GO:0065003 273 0.025
purine nucleotide metabolic process GO:0006163 229 0.025
response to extracellular stimulus GO:0009991 380 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
tissue development GO:0009888 252 0.025
transmembrane transport GO:0055085 412 0.024
regulation of multicellular organismal development GO:2000026 376 0.024
regulation of phosphate metabolic process GO:0019220 349 0.024
proteolysis GO:0006508 175 0.024
cellular catabolic process GO:0044248 295 0.024
positive regulation of phosphorylation GO:0042327 177 0.024
response to external biotic stimulus GO:0043207 221 0.024
positive regulation of rna metabolic process GO:0051254 203 0.024
ribose phosphate metabolic process GO:0019693 235 0.023
immune system process GO:0002376 204 0.023
regulation of protein modification process GO:0031399 194 0.023
positive regulation of cell communication GO:0010647 271 0.023
anatomical structure morphogenesis GO:0009653 298 0.023
positive regulation of nucleotide metabolic process GO:0045981 91 0.023
anion transport GO:0006820 178 0.023
organic substance catabolic process GO:1901575 316 0.022
positive regulation of multicellular organismal process GO:0051240 387 0.022
protein complex subunit organization GO:0071822 302 0.022
cellular response to nitrogen compound GO:1901699 210 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.022
organonitrogen compound biosynthetic process GO:1901566 167 0.022
protein transport GO:0015031 132 0.022
cellular metal ion homeostasis GO:0006875 172 0.022
cellular response to cytokine stimulus GO:0071345 127 0.022
intracellular transport GO:0046907 185 0.022
cellular response to organonitrogen compound GO:0071417 197 0.021
divalent inorganic cation homeostasis GO:0072507 165 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
response to estrogen GO:0043627 232 0.021
regulation of hydrolase activity GO:0051336 143 0.021
oxidation reduction process GO:0055114 304 0.021
metal ion transport GO:0030001 289 0.021
response to purine containing compound GO:0014074 126 0.020
ribonucleotide metabolic process GO:0009259 231 0.020
regulation of ion transport GO:0043269 245 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
cell type specific apoptotic process GO:0097285 134 0.020
regulation of neuron differentiation GO:0045664 208 0.020
regulation of nervous system development GO:0051960 264 0.020
calcium ion homeostasis GO:0055074 162 0.020
response to interleukin 1 GO:0070555 55 0.020
regulation of smooth muscle cell proliferation GO:0048660 75 0.020
sex differentiation GO:0007548 113 0.020
cyclic nucleotide metabolic process GO:0009187 80 0.020
response to vitamin GO:0033273 131 0.020
protein complex assembly GO:0006461 263 0.020
macromolecular complex subunit organization GO:0043933 339 0.019
localization of cell GO:0051674 202 0.019
regulation of kinase activity GO:0043549 117 0.019
multi organism reproductive process GO:0044703 262 0.019
dephosphorylation GO:0016311 98 0.019
positive regulation of protein modification process GO:0031401 142 0.019
regulation of secretion GO:0051046 224 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.018
wound healing GO:0042060 122 0.018
negative regulation of rna metabolic process GO:0051253 123 0.018
response to decreased oxygen levels GO:0036293 237 0.018
response to bacterium GO:0009617 200 0.018
metal ion homeostasis GO:0055065 186 0.018
positive regulation of cell development GO:0010720 176 0.018
negative regulation of cell proliferation GO:0008285 119 0.018
response to mechanical stimulus GO:0009612 134 0.018
synaptic transmission GO:0007268 235 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.018
catabolic process GO:0009056 351 0.018
mapk cascade GO:0000165 140 0.018
head development GO:0060322 247 0.018
amine metabolic process GO:0009308 38 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
leukocyte activation GO:0045321 76 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
response to glucocorticoid GO:0051384 223 0.017
cell migration GO:0016477 197 0.017
positive regulation of gene expression GO:0010628 244 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
protein oligomerization GO:0051259 191 0.017
positive regulation of molecular function GO:0044093 230 0.017
ion transmembrane transport GO:0034220 365 0.017
negative regulation of nucleic acid templated transcription GO:1903507 117 0.017
cell cycle GO:0007049 101 0.017
positive regulation of signaling GO:0023056 270 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
cellular protein localization GO:0034613 122 0.016
response to acid chemical GO:0001101 222 0.016
nucleoside phosphate biosynthetic process GO:1901293 102 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
negative regulation of viral process GO:0048525 4 0.016
response to peptide hormone GO:0043434 278 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
response to nutrient GO:0007584 248 0.016
purine containing compound catabolic process GO:0072523 138 0.016
regulation of response to external stimulus GO:0032101 106 0.016
positive regulation of hydrolase activity GO:0051345 86 0.015
divalent inorganic cation transport GO:0072511 134 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
negative regulation of viral genome replication GO:0045071 1 0.015
negative regulation of molecular function GO:0044092 133 0.015
regulation of protein kinase activity GO:0045859 105 0.015
response to tumor necrosis factor GO:0034612 56 0.015
regulation of mapk cascade GO:0043408 116 0.015
calcium ion transport GO:0006816 131 0.015
reactive oxygen species metabolic process GO:0072593 37 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
circulatory system process GO:0003013 183 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
response to peptide GO:1901652 292 0.015
purine ribonucleoside catabolic process GO:0046130 124 0.015
cellular response to oxygen levels GO:0071453 60 0.014
circulatory system development GO:0072359 134 0.014
single organism reproductive process GO:0044702 297 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
lipid localization GO:0010876 62 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
establishment of protein localization GO:0045184 141 0.014
signal release GO:0023061 145 0.014
multicellular organism reproduction GO:0032504 233 0.014
cellular response to fluid shear stress GO:0071498 4 0.014
muscle system process GO:0003012 115 0.014
negative regulation of signal transduction GO:0009968 83 0.014
cation homeostasis GO:0055080 195 0.014
lipid transport GO:0006869 61 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
regulation of secretion by cell GO:1903530 208 0.014
response to carbohydrate GO:0009743 183 0.014
single organism organelle organization GO:1902589 180 0.014
cellular component movement GO:0006928 248 0.014
positive regulation of ion transport GO:0043270 94 0.014
cytoplasmic transport GO:0016482 115 0.014
purine nucleotide biosynthetic process GO:0006164 83 0.014
locomotion GO:0040011 237 0.014
cellular amine metabolic process GO:0044106 38 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
multicellular organism growth GO:0035264 1 0.014
regulation of response to stress GO:0080134 126 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
smooth muscle cell proliferation GO:0048659 77 0.014
muscle cell proliferation GO:0033002 84 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
regulation of neurogenesis GO:0050767 247 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
cellular ketone metabolic process GO:0042180 51 0.013
nucleoside metabolic process GO:0009116 179 0.013
protein localization GO:0008104 191 0.013
positive regulation of cell death GO:0010942 184 0.013
dna metabolic process GO:0006259 96 0.013
gonad development GO:0008406 104 0.013
response to ketone GO:1901654 182 0.013
gastrulation GO:0007369 2 0.013
defense response GO:0006952 194 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
purine containing compound biosynthetic process GO:0072522 85 0.013
cell motility GO:0048870 202 0.013
reproductive structure development GO:0048608 128 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
potassium ion transmembrane transport GO:0071805 71 0.012
regulation of synaptic transmission GO:0050804 141 0.012
ribonucleotide biosynthetic process GO:0009260 85 0.012
regulation of dna metabolic process GO:0051052 60 0.012
amide transport GO:0042886 105 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
positive regulation of transferase activity GO:0051347 81 0.012
blood circulation GO:0008015 183 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
regulation of protein localization GO:0032880 81 0.012
response to monosaccharide GO:0034284 159 0.012
eye morphogenesis GO:0048592 4 0.012
peptide transport GO:0015833 97 0.012
potassium ion transport GO:0006813 97 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
multi multicellular organism process GO:0044706 138 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
response to reactive oxygen species GO:0000302 120 0.012
cellular response to oxidative stress GO:0034599 76 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.011
response to estradiol GO:0032355 164 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
viral genome replication GO:0019079 2 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
gland development GO:0048732 155 0.011
sexual reproduction GO:0019953 148 0.011
muscle structure development GO:0061061 87 0.011
regulation of body fluid levels GO:0050878 90 0.011
response to lipopolysaccharide GO:0032496 191 0.011
positive regulation of cell motility GO:2000147 97 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
carbohydrate homeostasis GO:0033500 75 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
aromatic compound catabolic process GO:0019439 168 0.011
response to hexose GO:0009746 144 0.011
regulation of cell growth GO:0001558 85 0.011
regulation of anatomical structure size GO:0090066 135 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
protein heterooligomerization GO:0051291 89 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
camp metabolic process GO:0046058 63 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
cation transmembrane transport GO:0098655 263 0.011
response to glucose GO:0009749 136 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
spermatogenesis GO:0007283 99 0.010
tonic smooth muscle contraction GO:0014820 4 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.010
cellular carbohydrate metabolic process GO:0044262 72 0.010
regulation of neuron projection development GO:0010975 161 0.010
response to biotic stimulus GO:0009607 226 0.010
membrane organization GO:0061024 94 0.010
regulation of cellular amine metabolic process GO:0033238 8 0.010
developmental process involved in reproduction GO:0003006 159 0.010
cardiovascular system development GO:0072358 134 0.010
oxoacid metabolic process GO:0043436 290 0.010
anatomical structure formation involved in morphogenesis GO:0048646 83 0.010
striated muscle tissue development GO:0014706 58 0.010
developmental growth GO:0048589 100 0.010
ras protein signal transduction GO:0007265 29 0.010

Isg20 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
sensory system disease DOID:0050155 0 0.022
eye and adnexa disease DOID:1492 0 0.016
eye disease DOID:5614 0 0.016
retinal disease DOID:5679 0 0.014
retinal degeneration DOID:8466 0 0.011