Rattus norvegicus

52 known processes

Bhmt

betaine-homocysteine methyltransferase

Bhmt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.232
cellular amino acid metabolic process GO:0006520 107 0.147
regulation of hormone levels GO:0010817 187 0.136
carboxylic acid metabolic process GO:0019752 289 0.135
organic acid metabolic process GO:0006082 292 0.128
store operated calcium entry GO:0002115 2 0.097
alpha amino acid metabolic process GO:1901605 71 0.091
lipid metabolic process GO:0006629 283 0.091
regulation of nucleic acid templated transcription GO:1903506 380 0.076
secretion GO:0046903 307 0.076
immune system process GO:0002376 204 0.073
regulation of rna biosynthetic process GO:2001141 381 0.070
organic acid biosynthetic process GO:0016053 83 0.068
lipid biosynthetic process GO:0008610 128 0.067
single organism biosynthetic process GO:0044711 342 0.066
regulation of cellular localization GO:0060341 263 0.065
response to nutrient levels GO:0031667 370 0.064
small molecule biosynthetic process GO:0044283 124 0.062
positive regulation of multicellular organismal process GO:0051240 387 0.061
aromatic compound catabolic process GO:0019439 168 0.061
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.060
cellular catabolic process GO:0044248 295 0.060
response to ethanol GO:0045471 162 0.058
regulation of secretion GO:0051046 224 0.057
response to extracellular stimulus GO:0009991 380 0.057
regulation of intracellular signal transduction GO:1902531 218 0.057
positive regulation of response to stimulus GO:0048584 285 0.052
cellular amino acid catabolic process GO:0009063 21 0.052
response to estrogen GO:0043627 232 0.052
catabolic process GO:0009056 351 0.051
organic substance catabolic process GO:1901575 316 0.050
negative regulation of macromolecule metabolic process GO:0010605 260 0.049
cellular lipid metabolic process GO:0044255 208 0.049
homeostatic process GO:0042592 331 0.049
regulation of transcription dna templated GO:0006355 374 0.048
positive regulation of cell communication GO:0010647 271 0.046
organic cyclic compound catabolic process GO:1901361 175 0.046
cellular hormone metabolic process GO:0034754 49 0.046
intracellular signal transduction GO:0035556 314 0.046
organonitrogen compound catabolic process GO:1901565 179 0.045
regulation of secretion by cell GO:1903530 208 0.045
ribonucleoside metabolic process GO:0009119 174 0.045
response to ketone GO:1901654 182 0.045
response to inorganic substance GO:0010035 377 0.044
coenzyme metabolic process GO:0006732 86 0.043
cell motility GO:0048870 202 0.042
rna biosynthetic process GO:0032774 380 0.041
protein phosphorylation GO:0006468 345 0.041
response to metal ion GO:0010038 253 0.041
aromatic amino acid family catabolic process GO:0009074 7 0.041
negative regulation of signaling GO:0023057 157 0.040
nucleic acid templated transcription GO:0097659 379 0.039
positive regulation of biosynthetic process GO:0009891 319 0.039
cellular ketone metabolic process GO:0042180 51 0.039
regulation of cellular ketone metabolic process GO:0010565 27 0.039
positive regulation of phosphorylation GO:0042327 177 0.038
small molecule catabolic process GO:0044282 59 0.038
central nervous system development GO:0007417 311 0.038
regulation of cell development GO:0060284 263 0.037
purine containing compound metabolic process GO:0072521 253 0.037
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.036
amine metabolic process GO:0009308 38 0.036
purine nucleoside metabolic process GO:0042278 169 0.036
regulation of cellular amine metabolic process GO:0033238 8 0.035
regulation of rna metabolic process GO:0051252 391 0.035
ion homeostasis GO:0050801 212 0.035
organelle organization GO:0006996 266 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.034
regulation of multicellular organismal development GO:2000026 376 0.034
g protein coupled receptor signaling pathway GO:0007186 242 0.034
regulation of neuron projection development GO:0010975 161 0.034
localization of cell GO:0051674 202 0.033
regulation of ion transport GO:0043269 245 0.033
cofactor metabolic process GO:0051186 95 0.033
nucleoside metabolic process GO:0009116 179 0.033
cellular nitrogen compound catabolic process GO:0044270 163 0.033
secretion by cell GO:0032940 248 0.032
nucleoside phosphate metabolic process GO:0006753 283 0.032
positive regulation of developmental process GO:0051094 283 0.032
regulation of cell proliferation GO:0042127 359 0.032
cellular response to external stimulus GO:0071496 118 0.032
cell projection organization GO:0030030 302 0.031
defense response GO:0006952 194 0.031
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
positive regulation of neurogenesis GO:0050769 165 0.031
negative regulation of cell death GO:0060548 229 0.031
cell cell signaling GO:0007267 335 0.030
fatty acid metabolic process GO:0006631 99 0.030
programmed cell death GO:0012501 392 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
transcription dna templated GO:0006351 377 0.030
positive regulation of nucleic acid templated transcription GO:1903508 197 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
response to peptide GO:1901652 292 0.029
negative regulation of programmed cell death GO:0043069 183 0.029
pteridine containing compound metabolic process GO:0042558 14 0.029
organophosphate metabolic process GO:0019637 370 0.029
nucleoside triphosphate metabolic process GO:0009141 144 0.028
regulation of phosphorylation GO:0042325 248 0.028
response to nutrient GO:0007584 248 0.027
regulation of immune system process GO:0002682 123 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
glycosyl compound metabolic process GO:1901657 182 0.027
regulation of nervous system development GO:0051960 264 0.027
peptide secretion GO:0002790 86 0.027
response to purine containing compound GO:0014074 126 0.026
cellular modified amino acid metabolic process GO:0006575 61 0.026
cellular amine metabolic process GO:0044106 38 0.026
chemical homeostasis GO:0048878 292 0.026
regulation of programmed cell death GO:0043067 341 0.026
brain development GO:0007420 247 0.025
positive regulation of secretion GO:0051047 140 0.025
regulation of peptide hormone secretion GO:0090276 80 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
negative regulation of transport GO:0051051 136 0.025
head development GO:0060322 247 0.025
negative regulation of gene expression GO:0010629 199 0.025
cellular response to nitrogen compound GO:1901699 210 0.025
regulation of cell differentiation GO:0045595 320 0.025
negative regulation of cellular metabolic process GO:0031324 281 0.025
positive regulation of gene expression GO:0010628 244 0.025
regulation of neuron differentiation GO:0045664 208 0.025
single organism reproductive process GO:0044702 297 0.024
positive regulation of transcription dna templated GO:0045893 197 0.024
positive regulation of cell proliferation GO:0008284 249 0.024
cellular chemical homeostasis GO:0055082 247 0.024
response to decreased oxygen levels GO:0036293 237 0.024
regulation of cellular component organization GO:0051128 368 0.024
positive regulation of rna metabolic process GO:0051254 203 0.024
cellular response to stress GO:0033554 269 0.024
response to glucose GO:0009749 136 0.023
heterocycle catabolic process GO:0046700 167 0.023
peptide hormone secretion GO:0030072 84 0.023
regulation of cell projection organization GO:0031344 175 0.023
organic acid catabolic process GO:0016054 49 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
aromatic amino acid family metabolic process GO:0009072 9 0.023
positive regulation of nervous system development GO:0051962 178 0.023
positive regulation of signaling GO:0023056 270 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.022
transcription from rna polymerase ii promoter GO:0006366 252 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
response to cytokine GO:0034097 215 0.022
thioester metabolic process GO:0035383 28 0.022
purine ribonucleoside metabolic process GO:0046128 168 0.022
negative regulation of metabolic process GO:0009892 331 0.022
positive regulation of intracellular signal transduction GO:1902533 138 0.022
regulation of response to stress GO:0080134 126 0.022
negative regulation of apoptotic process GO:0043066 181 0.021
hormone metabolic process GO:0042445 69 0.021
ossification GO:0001503 70 0.021
circulatory system process GO:0003013 183 0.021
regulation of protein modification process GO:0031399 194 0.021
muscle cell proliferation GO:0033002 84 0.021
single organism catabolic process GO:0044712 283 0.021
negative regulation of rna metabolic process GO:0051253 123 0.021
regulation of molecular function GO:0065009 398 0.021
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.020
regulation of phosphorus metabolic process GO:0051174 349 0.020
regulation of defense response GO:0031347 68 0.020
smooth muscle cell proliferation GO:0048659 77 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.020
regulation of signal transduction GO:0009966 318 0.020
circadian rhythm GO:0007623 88 0.020
response to organophosphorus GO:0046683 102 0.020
response to transition metal nanoparticle GO:1990267 122 0.020
neuron projection development GO:0031175 273 0.020
amide transport GO:0042886 105 0.020
rna metabolic process GO:0016070 406 0.019
locomotion GO:0040011 237 0.019
regulation of catalytic activity GO:0050790 304 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
positive regulation of protein modification process GO:0031401 142 0.019
multi organism reproductive process GO:0044703 262 0.019
response to peptide hormone GO:0043434 278 0.019
nucleobase containing compound catabolic process GO:0034655 152 0.019
cellular component biogenesis GO:0044085 368 0.019
cellular component assembly GO:0022607 360 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.019
liver development GO:0001889 90 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
cellular component movement GO:0006928 248 0.018
positive regulation of cell development GO:0010720 176 0.018
carboxylic acid biosynthetic process GO:0046394 83 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
regulation of homeostatic process GO:0032844 101 0.018
cellular cation homeostasis GO:0030003 180 0.018
alpha amino acid biosynthetic process GO:1901607 23 0.018
muscle system process GO:0003012 115 0.018
positive regulation of molecular function GO:0044093 230 0.018
cellular amino acid biosynthetic process GO:0008652 32 0.018
regulation of transferase activity GO:0051338 123 0.018
ribonucleoside triphosphate catabolic process GO:0009203 122 0.017
response to estradiol GO:0032355 164 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
response to vitamin GO:0033273 131 0.017
immune response GO:0006955 104 0.017
negative regulation of molecular function GO:0044092 133 0.017
divalent inorganic cation homeostasis GO:0072507 165 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
negative regulation of cell communication GO:0010648 158 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
negative regulation of transcription dna templated GO:0045892 116 0.017
regulation of neurogenesis GO:0050767 247 0.017
reproduction GO:0000003 245 0.017
monocarboxylic acid metabolic process GO:0032787 152 0.017
response to hexose GO:0009746 144 0.017
rhythmic process GO:0048511 156 0.017
regulation of locomotion GO:0040012 148 0.017
single organism organelle organization GO:1902589 180 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
regulation of smooth muscle cell proliferation GO:0048660 75 0.017
nucleoside phosphate catabolic process GO:1901292 140 0.016
mapk cascade GO:0000165 140 0.016
regulation of lipid metabolic process GO:0019216 68 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.016
calcium ion homeostasis GO:0055074 162 0.016
purine nucleoside catabolic process GO:0006152 124 0.016
sulfur compound metabolic process GO:0006790 70 0.016
cation homeostasis GO:0055080 195 0.016
response to radiation GO:0009314 137 0.016
response to corticosteroid GO:0031960 235 0.016
regulation of anatomical structure size GO:0090066 135 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
regulation of serine type peptidase activity GO:1902571 1 0.016
glycosyl compound catabolic process GO:1901658 126 0.016
alpha amino acid catabolic process GO:1901606 20 0.016
multicellular organism growth GO:0035264 1 0.016
nucleotide catabolic process GO:0009166 139 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
response to glucocorticoid GO:0051384 223 0.016
nucleoside catabolic process GO:0009164 126 0.015
negative regulation of hormone secretion GO:0046888 46 0.015
response to wounding GO:0009611 254 0.015
negative regulation of serine type endopeptidase activity GO:1900004 1 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
serine family amino acid metabolic process GO:0009069 12 0.015
monocarboxylic acid biosynthetic process GO:0072330 48 0.015
steroid metabolic process GO:0008202 73 0.015
dna metabolic process GO:0006259 96 0.015
neuron differentiation GO:0030182 368 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
regulation of peptide transport GO:0090087 87 0.015
macromolecular complex subunit organization GO:0043933 339 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
cellular homeostasis GO:0019725 252 0.015
metal ion homeostasis GO:0055065 186 0.015
nitrogen compound transport GO:0071705 229 0.015
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.015
toxin metabolic process GO:0009404 9 0.015
activation of protein kinase activity GO:0032147 47 0.015
gland development GO:0048732 155 0.014
multi multicellular organism process GO:0044706 138 0.014
positive regulation of blood circulation GO:1903524 65 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
positive regulation of immune system process GO:0002684 90 0.014
benzene containing compound metabolic process GO:0042537 22 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
tube development GO:0035295 89 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
response to oxygen levels GO:0070482 265 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
response to light stimulus GO:0009416 52 0.014
neurological system process GO:0050877 219 0.014
regulation of cellular component movement GO:0051270 150 0.014
organophosphate catabolic process GO:0046434 148 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.013
forebrain development GO:0030900 98 0.013
response to hypoxia GO:0001666 231 0.013
cellular response to peptide hormone stimulus GO:0071375 120 0.013
response to insulin GO:0032868 133 0.013
female pregnancy GO:0007565 122 0.013
synaptic transmission GO:0007268 235 0.013
monoamine transport GO:0015844 43 0.013
sulfur amino acid metabolic process GO:0000096 9 0.013
acetyl coa metabolic process GO:0006084 17 0.013
signal release GO:0023061 145 0.013
proteolysis GO:0006508 175 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
response to acid chemical GO:0001101 222 0.013
cellular response to peptide GO:1901653 133 0.013
developmental growth GO:0048589 100 0.013
ras protein signal transduction GO:0007265 29 0.013
growth GO:0040007 165 0.013
cellular response to endogenous stimulus GO:0071495 377 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
blood circulation GO:0008015 183 0.013
single organism behavior GO:0044708 130 0.013
apoptotic process GO:0006915 381 0.013
dicarboxylic acid metabolic process GO:0043648 42 0.013
regulation of pancreatic stellate cell proliferation GO:2000229 2 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
calcitriol biosynthetic process from calciol GO:0036378 2 0.012
nucleotide metabolic process GO:0009117 279 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
response to camp GO:0051591 91 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
oxidation reduction process GO:0055114 304 0.012
regulation of hydrolase activity GO:0051336 143 0.012
regulation of response to external stimulus GO:0032101 106 0.012
retinal metabolic process GO:0042574 3 0.012
ovulation cycle GO:0042698 67 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
hormone secretion GO:0046879 115 0.012
positive regulation of protein kinase activity GO:0045860 73 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
regulation of peptide secretion GO:0002791 82 0.012
response to growth factor GO:0070848 189 0.012
glycine metabolic process GO:0006544 7 0.012
heart morphogenesis GO:0003007 3 0.012
positive regulation of signal transduction GO:0009967 175 0.012
regulation of ion homeostasis GO:2000021 63 0.012
vascular process in circulatory system GO:0003018 96 0.012
cellular response to gonadotropin stimulus GO:0071371 17 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
regulation of hormone secretion GO:0046883 106 0.012
positive regulation of transport GO:0051050 245 0.012
regulation of protein metabolic process GO:0051246 289 0.012
steroid biosynthetic process GO:0006694 48 0.012
positive regulation of ion transport GO:0043270 94 0.012
cellular metal ion homeostasis GO:0006875 172 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
response to cocaine GO:0042220 39 0.011
peptidyl tyrosine phosphorylation GO:0018108 72 0.011
protein complex assembly GO:0006461 263 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
regulation of cell motility GO:2000145 131 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
multicellular organism reproduction GO:0032504 233 0.011
tissue development GO:0009888 252 0.011
cytoplasmic transport GO:0016482 115 0.011
nucleoside monophosphate metabolic process GO:0009123 93 0.011
response to zinc ion GO:0010043 39 0.011
macromolecular complex assembly GO:0065003 273 0.011
regulation of growth GO:0040008 105 0.011
regulation of apoptotic process GO:0042981 335 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
skeletal muscle cell differentiation GO:0035914 2 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
response to biotic stimulus GO:0009607 226 0.011
response to insecticide GO:0017085 21 0.011
isoprenoid metabolic process GO:0006720 45 0.011
regeneration GO:0031099 163 0.011
neuron development GO:0048666 286 0.011
protein complex biogenesis GO:0070271 263 0.010
hormone transport GO:0009914 121 0.010
olfactory learning GO:0008355 1 0.010
macromolecule localization GO:0033036 252 0.010
regulation of nucleotide catabolic process GO:0030811 65 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010
regulation of mapk cascade GO:0043408 116 0.010
regulation of protein transport GO:0051223 68 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
sexual reproduction GO:0019953 148 0.010
regulation of serine type endopeptidase activity GO:1900003 1 0.010
response to ammonium ion GO:0060359 71 0.010
positive regulation of blood coagulation GO:0030194 4 0.010
purine nucleoside triphosphate catabolic process GO:0009146 122 0.010

Bhmt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.041
inherited metabolic disorder DOID:655 0 0.041
disease of anatomical entity DOID:7 0 0.021
cardiovascular system disease DOID:1287 0 0.021
amino acid metabolic disorder DOID:9252 0 0.016
nervous system disease DOID:863 0 0.010
vascular disease DOID:178 0 0.010