Rattus norvegicus

42 known processes

Aloxe3

arachidonate lipoxygenase 3

Aloxe3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular protein metabolic process GO:0032268 267 0.049
Rat
regulation of multicellular organismal development GO:2000026 376 0.048
Rat
metal ion transport GO:0030001 289 0.046
cellular response to oxygen containing compound GO:1901701 386 0.046
cation transmembrane transport GO:0098655 263 0.043
regulation of rna biosynthetic process GO:2001141 381 0.041
cation transport GO:0006812 382 0.040
negative regulation of macromolecule metabolic process GO:0010605 260 0.039
cell motility GO:0048870 202 0.039
Rat
rna biosynthetic process GO:0032774 380 0.039
carboxylic acid metabolic process GO:0019752 289 0.038
transcription dna templated GO:0006351 377 0.037
intracellular signal transduction GO:0035556 314 0.036
response to inorganic substance GO:0010035 377 0.036
regulation of molecular function GO:0065009 398 0.034
Rat
rna metabolic process GO:0016070 406 0.032
chemical homeostasis GO:0048878 292 0.032
Mouse Rat
single organism biosynthetic process GO:0044711 342 0.031
regulation of cell differentiation GO:0045595 320 0.031
Rat
amine metabolic process GO:0009308 38 0.029
cellular response to lipid GO:0071396 201 0.029
Rat
response to nutrient levels GO:0031667 370 0.028
Rat
regulation of secretion by cell GO:1903530 208 0.028
organic acid metabolic process GO:0006082 292 0.028
sodium ion transport GO:0006814 82 0.027
response to molecule of bacterial origin GO:0002237 194 0.027
response to acid chemical GO:0001101 222 0.026
negative regulation of cellular metabolic process GO:0031324 281 0.026
cellular amine metabolic process GO:0044106 38 0.026
regulation of signal transduction GO:0009966 318 0.026
regulation of phosphate metabolic process GO:0019220 349 0.026
regulation of secretion GO:0051046 224 0.026
response to extracellular stimulus GO:0009991 380 0.025
Rat
homeostatic process GO:0042592 331 0.025
Mouse Rat
response to metal ion GO:0010038 253 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
metestrus GO:0060210 1 0.025
positive regulation of gene expression GO:0010628 244 0.025
Rat
regulation of rna metabolic process GO:0051252 391 0.025
regulation of transcription dna templated GO:0006355 374 0.024
cellular homeostasis GO:0019725 252 0.024
regulation of apoptotic process GO:0042981 335 0.024
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
negative regulation of metabolic process GO:0009892 331 0.024
reproductive process GO:0022414 372 0.024
localization of cell GO:0051674 202 0.024
Rat
regulation of protein metabolic process GO:0051246 289 0.024
Rat
proteolysis GO:0006508 175 0.024
Rat
regulation of catalytic activity GO:0050790 304 0.024
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
positive regulation of multicellular organismal process GO:0051240 387 0.023
Rat
cellular amino acid metabolic process GO:0006520 107 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
response to peptide GO:1901652 292 0.022
cellular component movement GO:0006928 248 0.021
Rat
regulation of cellular component organization GO:0051128 368 0.021
positive regulation of molecular function GO:0044093 230 0.021
Rat
regulation of phosphorylation GO:0042325 248 0.021
response to corticosteroid GO:0031960 235 0.021
positive regulation of developmental process GO:0051094 283 0.021
Rat
ion transmembrane transport GO:0034220 365 0.021
protein complex assembly GO:0006461 263 0.020
regulation of nervous system development GO:0051960 264 0.020
negative regulation of programmed cell death GO:0043069 183 0.020
Rat
secretion GO:0046903 307 0.020
regulation of nucleic acid templated transcription GO:1903506 380 0.020
positive regulation of cell differentiation GO:0045597 217 0.019
Rat
inorganic ion transmembrane transport GO:0098660 229 0.019
anatomical structure morphogenesis GO:0009653 298 0.019
response to peptide hormone GO:0043434 278 0.019
cell adhesion GO:0007155 110 0.019
Rat
inorganic cation transmembrane transport GO:0098662 202 0.019
response to oxygen levels GO:0070482 265 0.019
Rat
response to estrogen GO:0043627 232 0.019
cellular component assembly GO:0022607 360 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
response to decreased oxygen levels GO:0036293 237 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
negative regulation of biosynthetic process GO:0009890 168 0.018
muscle structure development GO:0061061 87 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
Rat
regulation of neurogenesis GO:0050767 247 0.018
cellular response to endogenous stimulus GO:0071495 377 0.018
transcription from rna polymerase ii promoter GO:0006366 252 0.018
cellular component biogenesis GO:0044085 368 0.018
cellular chemical homeostasis GO:0055082 247 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
multi organism reproductive process GO:0044703 262 0.018
cellular cation homeostasis GO:0030003 180 0.018
protein phosphorylation GO:0006468 345 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
neuron projection development GO:0031175 273 0.017
neuron differentiation GO:0030182 368 0.017
regulation of cellular localization GO:0060341 263 0.017
regulation of phosphorus metabolic process GO:0051174 349 0.017
transmembrane transport GO:0055085 412 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
Rat
regulation of protein phosphorylation GO:0001932 183 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
response to nutrient GO:0007584 248 0.017
Rat
single organism intracellular transport GO:1902582 166 0.017
ras protein signal transduction GO:0007265 29 0.017
regulation of cell proliferation GO:0042127 359 0.017
Rat
positive regulation of cell death GO:0010942 184 0.017
Rat
multicellular organismal reproductive process GO:0048609 233 0.017
response to bacterium GO:0009617 200 0.017
intracellular transport GO:0046907 185 0.016
biological adhesion GO:0022610 110 0.016
Rat
protein complex biogenesis GO:0070271 263 0.016
regulation of cell development GO:0060284 263 0.016
growth GO:0040007 165 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
regulation of protein modification process GO:0031399 194 0.016
tissue development GO:0009888 252 0.016
Rat
lipid metabolic process GO:0006629 283 0.016
negative regulation of gene expression GO:0010629 199 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
response to biotic stimulus GO:0009607 226 0.016
negative regulation of cell communication GO:0010648 158 0.016
cellular ion homeostasis GO:0006873 184 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
Rat
organic hydroxy compound metabolic process GO:1901615 115 0.016
gastrulation GO:0007369 2 0.016
axis specification GO:0009798 4 0.015
eye morphogenesis GO:0048592 4 0.015
nucleic acid templated transcription GO:0097659 379 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.015
negative regulation of cell death GO:0060548 229 0.015
Rat
cellular response to organonitrogen compound GO:0071417 197 0.015
neurological system process GO:0050877 219 0.015
macromolecular complex assembly GO:0065003 273 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
response to oxidative stress GO:0006979 186 0.015
response to glucocorticoid GO:0051384 223 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
cellular ketone metabolic process GO:0042180 51 0.015
immune system process GO:0002376 204 0.015
positive regulation of cell communication GO:0010647 271 0.015
cellular lipid metabolic process GO:0044255 208 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
Rat
protein localization GO:0008104 191 0.014
oxoacid metabolic process GO:0043436 290 0.014
small molecule biosynthetic process GO:0044283 124 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
tube development GO:0035295 89 0.014
reproduction GO:0000003 245 0.014
regulation of establishment of planar polarity GO:0090175 2 0.014
response to carbohydrate GO:0009743 183 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
cellular catabolic process GO:0044248 295 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
cytoplasmic transport GO:0016482 115 0.014
cell migration GO:0016477 197 0.014
Rat
central nervous system development GO:0007417 311 0.014
vesicle mediated transport GO:0016192 181 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
response to hexose GO:0009746 144 0.014
negative regulation of signaling GO:0023057 157 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
macromolecule localization GO:0033036 252 0.014
cellular response to stress GO:0033554 269 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
purine containing compound metabolic process GO:0072521 253 0.013
locomotion GO:0040011 237 0.013
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
programmed cell death GO:0012501 392 0.013
Rat
defense response GO:0006952 194 0.013
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.013
cytoskeleton organization GO:0007010 111 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
organophosphate metabolic process GO:0019637 370 0.013
metal ion homeostasis GO:0055065 186 0.013
regulation of cellular ketone metabolic process GO:0010565 27 0.013
organelle organization GO:0006996 266 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
regulation of locomotion GO:0040012 148 0.013
Rat
response to estradiol GO:0032355 164 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
cation homeostasis GO:0055080 195 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
Mouse
single organism reproductive process GO:0044702 297 0.013
establishment of tissue polarity GO:0007164 2 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
Rat
single organism cell adhesion GO:0098602 46 0.012
Rat
response to lipopolysaccharide GO:0032496 191 0.012
gland development GO:0048732 155 0.012
ion homeostasis GO:0050801 212 0.012
Rat
regulation of anatomical structure size GO:0090066 135 0.012
Rat
retina morphogenesis in camera type eye GO:0060042 1 0.012
response to hypoxia GO:0001666 231 0.012
developmental process involved in reproduction GO:0003006 159 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
calcium ion homeostasis GO:0055074 162 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
regulation of membrane potential GO:0042391 110 0.012
Rat
regulation of growth GO:0040008 105 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
circulatory system process GO:0003013 183 0.012
Rat
regulation of kinase activity GO:0043549 117 0.012
apoptotic process GO:0006915 381 0.012
Rat
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
cellular response to alcohol GO:0097306 87 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
Rat
anterior posterior pattern specification GO:0009952 1 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
positive regulation of rna metabolic process GO:0051254 203 0.012
negative regulation of molecular function GO:0044092 133 0.012
response to other organism GO:0051707 220 0.011
multicellular organism reproduction GO:0032504 233 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
gamete generation GO:0007276 124 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
urogenital system development GO:0001655 78 0.011
divalent metal ion transport GO:0070838 132 0.011
cellular response to peptide GO:1901653 133 0.011
response to ethanol GO:0045471 162 0.011
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.011
single organism catabolic process GO:0044712 283 0.011
neural crest cell differentiation GO:0014033 2 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
macromolecular complex subunit organization GO:0043933 339 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
blood circulation GO:0008015 183 0.011
Rat
small gtpase mediated signal transduction GO:0007264 36 0.011
response to monosaccharide GO:0034284 159 0.011
positive regulation of cell development GO:0010720 176 0.011
regulation of neuron projection development GO:0010975 161 0.011
single organism behavior GO:0044708 130 0.011
glucose homeostasis GO:0042593 75 0.011
regulation of blood vessel size GO:0050880 89 0.011
Rat
response to glucose GO:0009749 136 0.011
regulation of programmed cell death GO:0043067 341 0.011
Rat
hormone transport GO:0009914 121 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
brain development GO:0007420 247 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
cyclic nucleotide biosynthetic process GO:0009190 63 0.011
regulation of neuron differentiation GO:0045664 208 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
regulation of cell projection size GO:0032536 1 0.011
exocytosis GO:0006887 60 0.010
regulation of transferase activity GO:0051338 123 0.010
heterocycle catabolic process GO:0046700 167 0.010
lipid biosynthetic process GO:0008610 128 0.010
adult locomotory behavior GO:0008344 4 0.010
calcium ion transport GO:0006816 131 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
positive regulation of signaling GO:0023056 270 0.010

Aloxe3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
sensory system disease DOID:0050155 0 0.015
retinal disease DOID:5679 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014
disease of metabolism DOID:0014667 0 0.011
gastrointestinal system disease DOID:77 0 0.010