Rattus norvegicus

0 known processes

Tmco4

transmembrane and coiled-coil domains 4

(Aliases: MGC124660)

Tmco4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to inorganic substance GO:0010035 377 0.081
regulation of phosphate metabolic process GO:0019220 349 0.079
organic acid metabolic process GO:0006082 292 0.072
regulation of transcription dna templated GO:0006355 374 0.070
oxoacid metabolic process GO:0043436 290 0.068
response to nutrient GO:0007584 248 0.064
response to extracellular stimulus GO:0009991 380 0.064
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.063
rna biosynthetic process GO:0032774 380 0.062
regulation of anatomical structure morphogenesis GO:0022603 141 0.062
carboxylic acid metabolic process GO:0019752 289 0.060
transcription dna templated GO:0006351 377 0.058
positive regulation of rna biosynthetic process GO:1902680 197 0.056
regulation of molecular function GO:0065009 398 0.056
cellular response to oxygen containing compound GO:1901701 386 0.055
nucleic acid templated transcription GO:0097659 379 0.055
regulation of rna biosynthetic process GO:2001141 381 0.055
rna metabolic process GO:0016070 406 0.054
intracellular signal transduction GO:0035556 314 0.053
regulation of programmed cell death GO:0043067 341 0.050
regulation of rna metabolic process GO:0051252 391 0.050
cellular response to endogenous stimulus GO:0071495 377 0.050
positive regulation of cellular biosynthetic process GO:0031328 295 0.049
response to nutrient levels GO:0031667 370 0.049
response to external biotic stimulus GO:0043207 221 0.048
negative regulation of metabolic process GO:0009892 331 0.047
apoptotic process GO:0006915 381 0.046
cellular ketone metabolic process GO:0042180 51 0.046
response to other organism GO:0051707 220 0.045
response to lipopolysaccharide GO:0032496 191 0.044
response to metal ion GO:0010038 253 0.044
positive regulation of biosynthetic process GO:0009891 319 0.044
programmed cell death GO:0012501 392 0.044
regulation of protein metabolic process GO:0051246 289 0.043
response to oxygen levels GO:0070482 265 0.043
catabolic process GO:0009056 351 0.043
cation transport GO:0006812 382 0.043
regulation of phosphorus metabolic process GO:0051174 349 0.042
secretion GO:0046903 307 0.042
positive regulation of response to stimulus GO:0048584 285 0.042
carbohydrate derivative metabolic process GO:1901135 346 0.041
regulation of nucleic acid templated transcription GO:1903506 380 0.041
response to peptide hormone GO:0043434 278 0.040
response to molecule of bacterial origin GO:0002237 194 0.039
regulation of cell proliferation GO:0042127 359 0.039
regulation of cellular component organization GO:0051128 368 0.039
regulation of cellular ketone metabolic process GO:0010565 27 0.039
positive regulation of cell proliferation GO:0008284 249 0.039
regulation of multicellular organismal development GO:2000026 376 0.039
cellular response to cytokine stimulus GO:0071345 127 0.038
nucleoside phosphate metabolic process GO:0006753 283 0.038
regulation of apoptotic process GO:0042981 335 0.037
negative regulation of cellular metabolic process GO:0031324 281 0.037
cellular component assembly GO:0022607 360 0.037
response to biotic stimulus GO:0009607 226 0.036
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.036
nucleobase containing small molecule metabolic process GO:0055086 316 0.036
cellular response to stress GO:0033554 269 0.036
positive regulation of molecular function GO:0044093 230 0.035
neuron projection development GO:0031175 273 0.034
aging GO:0007568 241 0.034
anatomical structure morphogenesis GO:0009653 298 0.034
regulation of cellular protein metabolic process GO:0032268 267 0.034
immune system process GO:0002376 204 0.034
macromolecular complex assembly GO:0065003 273 0.033
protein phosphorylation GO:0006468 345 0.033
transcription from rna polymerase ii promoter GO:0006366 252 0.033
positive regulation of transcription dna templated GO:0045893 197 0.033
positive regulation of nucleic acid templated transcription GO:1903508 197 0.033
cellular response to lipid GO:0071396 201 0.032
response to bacterium GO:0009617 200 0.032
cellular response to nitrogen compound GO:1901699 210 0.032
cellular component movement GO:0006928 248 0.032
reproductive process GO:0022414 372 0.032
central nervous system development GO:0007417 311 0.032
organophosphate metabolic process GO:0019637 370 0.032
purine containing compound metabolic process GO:0072521 253 0.032
defense response GO:0006952 194 0.031
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.031
response to cytokine GO:0034097 215 0.031
positive regulation of rna metabolic process GO:0051254 203 0.031
positive regulation of phosphate metabolic process GO:0045937 262 0.031
negative regulation of gene expression GO:0010629 199 0.031
positive regulation of gene expression GO:0010628 244 0.030
nucleotide metabolic process GO:0009117 279 0.030
cellular response to hormone stimulus GO:0032870 247 0.030
regulation of signal transduction GO:0009966 318 0.030
single organism reproductive process GO:0044702 297 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.029
regulation of phosphorylation GO:0042325 248 0.029
response to hypoxia GO:0001666 231 0.029
cellular component biogenesis GO:0044085 368 0.029
macromolecular complex subunit organization GO:0043933 339 0.029
negative regulation of programmed cell death GO:0043069 183 0.029
positive regulation of protein metabolic process GO:0051247 178 0.029
regulation of cell differentiation GO:0045595 320 0.028
cellular catabolic process GO:0044248 295 0.028
negative regulation of multicellular organismal process GO:0051241 203 0.028
cellular component morphogenesis GO:0032989 155 0.028
organelle organization GO:0006996 266 0.028
locomotion GO:0040011 237 0.028
cellular amine metabolic process GO:0044106 38 0.028
localization of cell GO:0051674 202 0.027
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
protein oligomerization GO:0051259 191 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.027
response to acid chemical GO:0001101 222 0.027
anion transport GO:0006820 178 0.027
cellular amino acid metabolic process GO:0006520 107 0.027
oxidation reduction process GO:0055114 304 0.027
intracellular transport GO:0046907 185 0.027
monocarboxylic acid metabolic process GO:0032787 152 0.027
positive regulation of cellular protein metabolic process GO:0032270 167 0.027
chemical homeostasis GO:0048878 292 0.026
response to oxidative stress GO:0006979 186 0.026
positive regulation of programmed cell death GO:0043068 157 0.026
ion transmembrane transport GO:0034220 365 0.026
biological adhesion GO:0022610 110 0.026
response to ethanol GO:0045471 162 0.026
immune response GO:0006955 104 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
response to peptide GO:1901652 292 0.026
positive regulation of cell death GO:0010942 184 0.026
protein complex subunit organization GO:0071822 302 0.026
response to estrogen GO:0043627 232 0.026
single organism catabolic process GO:0044712 283 0.026
reproduction GO:0000003 245 0.025
regulation of cell development GO:0060284 263 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
regulation of catalytic activity GO:0050790 304 0.025
regulation of response to stress GO:0080134 126 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.025
regulation of locomotion GO:0040012 148 0.025
neuron development GO:0048666 286 0.025
protein complex assembly GO:0006461 263 0.025
macromolecule localization GO:0033036 252 0.025
cellular response to organonitrogen compound GO:0071417 197 0.025
neuron differentiation GO:0030182 368 0.024
ribose phosphate metabolic process GO:0019693 235 0.024
leukocyte activation GO:0045321 76 0.024
regulation of secretion GO:0051046 224 0.024
homeostatic process GO:0042592 331 0.024
negative regulation of cell death GO:0060548 229 0.024
cellular response to peptide GO:1901653 133 0.024
cell migration GO:0016477 197 0.024
regulation of intracellular signal transduction GO:1902531 218 0.024
positive regulation of apoptotic process GO:0043065 154 0.024
positive regulation of developmental process GO:0051094 283 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
protein complex biogenesis GO:0070271 263 0.023
regulation of immune system process GO:0002682 123 0.023
response to insulin GO:0032868 133 0.023
cell motility GO:0048870 202 0.023
nitrogen compound transport GO:0071705 229 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
response to growth factor GO:0070848 189 0.023
single organism biosynthetic process GO:0044711 342 0.023
ribonucleotide metabolic process GO:0009259 231 0.023
organic substance catabolic process GO:1901575 316 0.023
positive regulation of phosphorylation GO:0042327 177 0.022
amine metabolic process GO:0009308 38 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
glycosyl compound metabolic process GO:1901657 182 0.022
heterocycle catabolic process GO:0046700 167 0.022
negative regulation of rna biosynthetic process GO:1902679 118 0.022
negative regulation of transport GO:0051051 136 0.022
single organism intracellular transport GO:1902582 166 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
positive regulation of signaling GO:0023056 270 0.021
regulation of cellular localization GO:0060341 263 0.021
cell cell signaling GO:0007267 335 0.021
proteolysis GO:0006508 175 0.021
transmembrane transport GO:0055085 412 0.021
cell projection organization GO:0030030 302 0.021
nucleoside triphosphate metabolic process GO:0009141 144 0.020
nucleoside metabolic process GO:0009116 179 0.020
multi organism reproductive process GO:0044703 262 0.020
regulation of nervous system development GO:0051960 264 0.020
cellular chemical homeostasis GO:0055082 247 0.020
multicellular organism reproduction GO:0032504 233 0.020
response to mechanical stimulus GO:0009612 134 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.020
metal ion transport GO:0030001 289 0.020
positive regulation of transport GO:0051050 245 0.020
response to reactive oxygen species GO:0000302 120 0.020
ribonucleoside metabolic process GO:0009119 174 0.020
regulation of neurogenesis GO:0050767 247 0.020
cellular lipid metabolic process GO:0044255 208 0.020
secretion by cell GO:0032940 248 0.020
gland development GO:0048732 155 0.019
carboxylic acid transport GO:0046942 115 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
cellular response to peptide hormone stimulus GO:0071375 120 0.019
regeneration GO:0031099 163 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
metal ion homeostasis GO:0055065 186 0.019
cell activation GO:0001775 97 0.019
regulation of hormone levels GO:0010817 187 0.019
regulation of hydrolase activity GO:0051336 143 0.019
establishment of protein localization GO:0045184 141 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
response to amino acid GO:0043200 75 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
response to transition metal nanoparticle GO:1990267 122 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
peptidyl amino acid modification GO:0018193 126 0.018
cell morphogenesis GO:0000902 142 0.018
purine containing compound catabolic process GO:0072523 138 0.018
head development GO:0060322 247 0.018
positive regulation of protein modification process GO:0031401 142 0.018
ion homeostasis GO:0050801 212 0.018
response to wounding GO:0009611 254 0.018
cell part morphogenesis GO:0032990 123 0.018
regulation of cell migration GO:0030334 128 0.018
lipid metabolic process GO:0006629 283 0.018
positive regulation of cell development GO:0010720 176 0.018
tissue development GO:0009888 252 0.018
cellular ion homeostasis GO:0006873 184 0.018
response to decreased oxygen levels GO:0036293 237 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.017
peptide transport GO:0015833 97 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
response to estradiol GO:0032355 164 0.017
gastrulation GO:0007369 2 0.017
cellular response to insulin stimulus GO:0032869 81 0.017
positive regulation of cellular component movement GO:0051272 102 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
response to glucocorticoid GO:0051384 223 0.017
cellular cation homeostasis GO:0030003 180 0.017
negative regulation of transcription dna templated GO:0045892 116 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
positive regulation of signal transduction GO:0009967 175 0.017
regulation of secretion by cell GO:1903530 208 0.017
reactive oxygen species biosynthetic process GO:1903409 8 0.017
hormone transport GO:0009914 121 0.017
reproductive system development GO:0061458 128 0.017
cellular response to tumor necrosis factor GO:0071356 46 0.017
reactive oxygen species metabolic process GO:0072593 37 0.017
organic cyclic compound catabolic process GO:1901361 175 0.016
developmental process involved in reproduction GO:0003006 159 0.016
ribonucleoside triphosphate metabolic process GO:0009199 141 0.016
brain development GO:0007420 247 0.016
negative regulation of secretion GO:0051048 82 0.016
organic anion transport GO:0015711 132 0.016
reproductive structure development GO:0048608 128 0.016
regulation of cell motility GO:2000145 131 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
regulation of protein modification process GO:0031399 194 0.016
regulation of system process GO:0044057 208 0.016
nucleoside catabolic process GO:0009164 126 0.016
regulation of neuron differentiation GO:0045664 208 0.016
reactive nitrogen species metabolic process GO:2001057 1 0.016
aromatic compound catabolic process GO:0019439 168 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
cell adhesion GO:0007155 110 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
purine nucleotide catabolic process GO:0006195 136 0.016
regulation of cell morphogenesis GO:0022604 77 0.016
mesenchymal cell proliferation GO:0010463 4 0.016
negative regulation of molecular function GO:0044092 133 0.016
ras protein signal transduction GO:0007265 29 0.016
positive regulation of cell motility GO:2000147 97 0.016
negative regulation of developmental process GO:0051093 125 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.015
positive regulation of multicellular organismal process GO:0051240 387 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
regulation of response to external stimulus GO:0032101 106 0.015
cellular homeostasis GO:0019725 252 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
divalent inorganic cation transport GO:0072511 134 0.015
cation transmembrane transport GO:0098655 263 0.015
hormone secretion GO:0046879 115 0.015
regulation of neuron projection development GO:0010975 161 0.015
negative regulation of rna metabolic process GO:0051253 123 0.015
cellular response to external stimulus GO:0071496 118 0.015
enzyme linked receptor protein signaling pathway GO:0007167 116 0.015
cellular response to steroid hormone stimulus GO:0071383 93 0.015
response to hydrogen peroxide GO:0042542 89 0.015
calcium ion homeostasis GO:0055074 162 0.015
signal release GO:0023061 145 0.014
neurological system process GO:0050877 219 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
sex differentiation GO:0007548 113 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
cellular response to reactive oxygen species GO:0034614 55 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
embryonic pattern specification GO:0009880 1 0.014
peptide hormone secretion GO:0030072 84 0.014
cation homeostasis GO:0055080 195 0.014
rhythmic process GO:0048511 156 0.014
positive regulation of hydrolase activity GO:0051345 86 0.014
regulation of mesenchymal cell proliferation GO:0010464 4 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
regulation of membrane potential GO:0042391 110 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
amide transport GO:0042886 105 0.014
negative regulation of signaling GO:0023057 157 0.014
response to interleukin 1 GO:0070555 55 0.014
positive regulation of cell communication GO:0010647 271 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
dendrite development GO:0016358 72 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
regulation of cell projection organization GO:0031344 175 0.013
protein heterooligomerization GO:0051291 89 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
gliogenesis GO:0042063 93 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
regulation of cellular component movement GO:0051270 150 0.013
regulation of cell activation GO:0050865 50 0.013
lipid biosynthetic process GO:0008610 128 0.013
anterior posterior pattern specification GO:0009952 1 0.013
nucleotide catabolic process GO:0009166 139 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
regulation of cellular component biogenesis GO:0044087 86 0.013
b cell mediated immunity GO:0019724 4 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
response to vitamin GO:0033273 131 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
gonad development GO:0008406 104 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
lipid transport GO:0006869 61 0.012
positive regulation of nervous system development GO:0051962 178 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
positive regulation of locomotion GO:0040017 102 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
regulation of establishment of protein localization GO:0070201 69 0.012
cellular macromolecule localization GO:0070727 122 0.012
response to ketone GO:1901654 182 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
development of primary sexual characteristics GO:0045137 107 0.012
cytoplasmic transport GO:0016482 115 0.012
mapk cascade GO:0000165 140 0.012
response to tumor necrosis factor GO:0034612 56 0.012
dephosphorylation GO:0016311 98 0.012
response to corticosteroid GO:0031960 235 0.012
divalent metal ion transport GO:0070838 132 0.012
positive regulation of secretion GO:0051047 140 0.012
calcium ion transport GO:0006816 131 0.012
cytokine biosynthetic process GO:0042089 3 0.012
small molecule biosynthetic process GO:0044283 124 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
protein transport GO:0015031 132 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
regulation of establishment of planar polarity GO:0090175 2 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
positive regulation of cell migration GO:0030335 96 0.012
neuron projection morphogenesis GO:0048812 122 0.012
single organism organelle organization GO:1902589 180 0.011
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
response to carbohydrate GO:0009743 183 0.011
lipid localization GO:0010876 62 0.011
positive regulation of immune system process GO:0002684 90 0.011
vesicle mediated transport GO:0016192 181 0.011
salivary gland development GO:0007431 3 0.011
learning or memory GO:0007611 90 0.011
negative regulation of secretion by cell GO:1903531 72 0.011
lipid storage GO:0019915 1 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
synaptic transmission GO:0007268 235 0.011
cell projection morphogenesis GO:0048858 123 0.011
response to radiation GO:0009314 137 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
response to toxic substance GO:0009636 133 0.011
circulatory system process GO:0003013 183 0.011
liver development GO:0001889 90 0.011
carboxylic acid biosynthetic process GO:0046394 83 0.011
cell type specific apoptotic process GO:0097285 134 0.011
gamete generation GO:0007276 124 0.011
maintenance of location GO:0051235 17 0.011
cellular response to oxidative stress GO:0034599 76 0.011
action potential GO:0001508 54 0.011
response to alkaloid GO:0043279 132 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
regulation of mapk cascade GO:0043408 116 0.011
regulation of metal ion transport GO:0010959 118 0.011
response to temperature stimulus GO:0009266 94 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
neuronal action potential GO:0019228 35 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
epithelium development GO:0060429 96 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
axon development GO:0061564 96 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
muscle cell proliferation GO:0033002 84 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
muscle system process GO:0003012 115 0.010
negative regulation of cell communication GO:0010648 158 0.010
organic hydroxy compound metabolic process GO:1901615 115 0.010
multicellular organism growth GO:0035264 1 0.010
membrane organization GO:0061024 94 0.010
positive regulation of secretion by cell GO:1903532 128 0.010
dna metabolic process GO:0006259 96 0.010
inflammatory response GO:0006954 150 0.010
cytokine production GO:0001816 61 0.010
axis specification GO:0009798 4 0.010
sexual reproduction GO:0019953 148 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
organic acid transport GO:0015849 116 0.010
positive regulation of nucleotide metabolic process GO:0045981 91 0.010
regulation of ion transport GO:0043269 245 0.010
regulation of immune response GO:0050776 55 0.010
protein localization GO:0008104 191 0.010
regulation of hormone secretion GO:0046883 106 0.010
carbohydrate metabolic process GO:0005975 130 0.010

Tmco4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.031
disease of metabolism DOID:0014667 0 0.016
central nervous system disease DOID:331 0 0.015
musculoskeletal system disease DOID:17 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
sensory system disease DOID:0050155 0 0.011
inherited metabolic disorder DOID:655 0 0.010
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010