Rattus norvegicus

0 known processes

Hipk4

homeodomain interacting protein kinase 4

Hipk4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of protein metabolic process GO:0051246 289 0.086
regulation of rna metabolic process GO:0051252 391 0.064
cation transport GO:0006812 382 0.063
homeostatic process GO:0042592 331 0.063
regulation of programmed cell death GO:0043067 341 0.061
Fly
apoptotic process GO:0006915 381 0.060
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.058
cellular response to oxygen containing compound GO:1901701 386 0.058
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.057
negative regulation of metabolic process GO:0009892 331 0.056
regulation of phosphate metabolic process GO:0019220 349 0.056
programmed cell death GO:0012501 392 0.056
Fly
protein phosphorylation GO:0006468 345 0.055
Mouse Fly
regulation of molecular function GO:0065009 398 0.054
transmembrane transport GO:0055085 412 0.051
positive regulation of biosynthetic process GO:0009891 319 0.049
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.048
transcription dna templated GO:0006351 377 0.047
regulation of catalytic activity GO:0050790 304 0.045
transcription from rna polymerase ii promoter GO:0006366 252 0.045
nucleic acid templated transcription GO:0097659 379 0.044
regulation of apoptotic process GO:0042981 335 0.044
cellular amino acid metabolic process GO:0006520 107 0.044
organophosphate metabolic process GO:0019637 370 0.044
negative regulation of macromolecule metabolic process GO:0010605 260 0.043
response to nutrient levels GO:0031667 370 0.042
cellular response to stress GO:0033554 269 0.042
brain development GO:0007420 247 0.042
response to inorganic substance GO:0010035 377 0.040
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.040
positive regulation of cell proliferation GO:0008284 249 0.040
anatomical structure morphogenesis GO:0009653 298 0.040
Fly
cellular response to endogenous stimulus GO:0071495 377 0.040
regulation of signal transduction GO:0009966 318 0.039
Mouse Fly
regulation of system process GO:0044057 208 0.039
rna biosynthetic process GO:0032774 380 0.038
response to peptide GO:1901652 292 0.038
positive regulation of signaling GO:0023056 270 0.038
Fly
positive regulation of cell communication GO:0010647 271 0.038
Fly
regulation of cellular protein metabolic process GO:0032268 267 0.037
regulation of protein phosphorylation GO:0001932 183 0.037
negative regulation of cellular metabolic process GO:0031324 281 0.037
regulation of transcription dna templated GO:0006355 374 0.037
positive regulation of gene expression GO:0010628 244 0.036
neuron development GO:0048666 286 0.036
intracellular signal transduction GO:0035556 314 0.036
Mouse Fly
positive regulation of phosphorylation GO:0042327 177 0.036
regulation of rna biosynthetic process GO:2001141 381 0.035
secretion GO:0046903 307 0.035
regulation of cellular amino acid metabolic process GO:0006521 2 0.035
tissue development GO:0009888 252 0.034
cellular component morphogenesis GO:0032989 155 0.034
cellular amine metabolic process GO:0044106 38 0.034
organic acid metabolic process GO:0006082 292 0.034
regulation of nucleic acid templated transcription GO:1903506 380 0.034
response to extracellular stimulus GO:0009991 380 0.034
regulation of cell differentiation GO:0045595 320 0.033
positive regulation of cellular biosynthetic process GO:0031328 295 0.033
regulation of phosphorylation GO:0042325 248 0.033
positive regulation of cellular protein metabolic process GO:0032270 167 0.033
ion homeostasis GO:0050801 212 0.032
positive regulation of molecular function GO:0044093 230 0.032
oxidation reduction process GO:0055114 304 0.031
positive regulation of phosphorus metabolic process GO:0010562 262 0.031
cellular catabolic process GO:0044248 295 0.031
positive regulation of phosphate metabolic process GO:0045937 262 0.031
anion transport GO:0006820 178 0.031
cell cycle GO:0007049 101 0.031
central nervous system development GO:0007417 311 0.031
neuron projection development GO:0031175 273 0.031
response to estrogen GO:0043627 232 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.030
regulation of protein modification process GO:0031399 194 0.030
cell morphogenesis GO:0000902 142 0.030
neuron differentiation GO:0030182 368 0.030
cellular chemical homeostasis GO:0055082 247 0.030
regulation of cellular amine metabolic process GO:0033238 8 0.030
positive regulation of protein metabolic process GO:0051247 178 0.030
lipid metabolic process GO:0006629 283 0.029
head development GO:0060322 247 0.029
positive regulation of catalytic activity GO:0043085 184 0.029
cation homeostasis GO:0055080 195 0.029
carboxylic acid metabolic process GO:0019752 289 0.029
regulation of cellular component organization GO:0051128 368 0.028
macromolecule localization GO:0033036 252 0.028
cellular homeostasis GO:0019725 252 0.028
regulation of phosphorus metabolic process GO:0051174 349 0.028
positive regulation of rna metabolic process GO:0051254 203 0.028
macromolecular complex assembly GO:0065003 273 0.028
amine metabolic process GO:0009308 38 0.028
catabolic process GO:0009056 351 0.027
neurological system process GO:0050877 219 0.027
carbohydrate derivative metabolic process GO:1901135 346 0.027
cell projection organization GO:0030030 302 0.027
negative regulation of cell death GO:0060548 229 0.027
cellular component movement GO:0006928 248 0.027
organelle organization GO:0006996 266 0.027
Mouse
cellular response to organonitrogen compound GO:0071417 197 0.027
g protein coupled receptor signaling pathway GO:0007186 242 0.027
response to wounding GO:0009611 254 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
Mouse
response to radiation GO:0009314 137 0.026
cellular response to peptide GO:1901653 133 0.026
nucleotide metabolic process GO:0009117 279 0.026
regulation of intracellular signal transduction GO:1902531 218 0.026
Mouse Fly
positive regulation of response to stimulus GO:0048584 285 0.026
Fly
negative regulation of protein metabolic process GO:0051248 114 0.025
cell projection morphogenesis GO:0048858 123 0.025
defense response GO:0006952 194 0.025
negative regulation of programmed cell death GO:0043069 183 0.025
negative regulation of apoptotic process GO:0043066 181 0.025
cellular ion homeostasis GO:0006873 184 0.024
rna metabolic process GO:0016070 406 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
positive regulation of kinase activity GO:0033674 77 0.024
organic substance catabolic process GO:1901575 316 0.024
small gtpase mediated signal transduction GO:0007264 36 0.024
proteolysis GO:0006508 175 0.024
protein oligomerization GO:0051259 191 0.024
response to estradiol GO:0032355 164 0.024
positive regulation of developmental process GO:0051094 283 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
single organism carbohydrate metabolic process GO:0044723 118 0.023
blood circulation GO:0008015 183 0.023
ion transmembrane transport GO:0034220 365 0.023
positive regulation of cell death GO:0010942 184 0.023
organic anion transport GO:0015711 132 0.023
positive regulation of rna biosynthetic process GO:1902680 197 0.022
protein complex biogenesis GO:0070271 263 0.022
cation transmembrane transport GO:0098655 263 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
positive regulation of protein modification process GO:0031401 142 0.022
protein processing GO:0016485 68 0.022
developmental process involved in reproduction GO:0003006 159 0.022
cellular component assembly GO:0022607 360 0.022
neuron projection morphogenesis GO:0048812 122 0.022
protein complex assembly GO:0006461 263 0.022
regulation of cell proliferation GO:0042127 359 0.021
cellular response to hormone stimulus GO:0032870 247 0.021
secretion by cell GO:0032940 248 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
oxoacid metabolic process GO:0043436 290 0.021
purine containing compound metabolic process GO:0072521 253 0.021
response to organophosphorus GO:0046683 102 0.021
negative regulation of cell communication GO:0010648 158 0.021
carbohydrate derivative biosynthetic process GO:1901137 124 0.021
axon development GO:0061564 96 0.021
regulation of ion transport GO:0043269 245 0.020
circulatory system process GO:0003013 183 0.020
cellular component biogenesis GO:0044085 368 0.020
multicellular organism reproduction GO:0032504 233 0.020
response to oxygen levels GO:0070482 265 0.020
cellular metal ion homeostasis GO:0006875 172 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
spindle organization GO:0007051 2 0.020
heterocycle catabolic process GO:0046700 167 0.019
cellular cation homeostasis GO:0030003 180 0.019
cellular ketone metabolic process GO:0042180 51 0.019
organ morphogenesis GO:0009887 75 0.019
Fly
response to peptide hormone GO:0043434 278 0.019
metal ion transport GO:0030001 289 0.019
chromosome segregation GO:0007059 2 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
multicellular organismal reproductive process GO:0048609 233 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
divalent inorganic cation homeostasis GO:0072507 165 0.018
regulation of multicellular organismal development GO:2000026 376 0.018
protein maturation GO:0051604 68 0.018
negative regulation of signaling GO:0023057 157 0.018
response to hypoxia GO:0001666 231 0.018
single organism catabolic process GO:0044712 283 0.018
negative regulation of gene expression GO:0010629 199 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
peptidyl amino acid modification GO:0018193 126 0.018
Mouse
positive regulation of cellular component organization GO:0051130 200 0.018
nitrogen compound transport GO:0071705 229 0.018
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
regulation of anatomical structure size GO:0090066 135 0.017
chemical homeostasis GO:0048878 292 0.017
single organism organelle organization GO:1902589 180 0.017
Mouse
single organism biosynthetic process GO:0044711 342 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
protein complex subunit organization GO:0071822 302 0.017
anterior posterior pattern specification GO:0009952 1 0.017
regulation of transferase activity GO:0051338 123 0.017
regulation of kinase activity GO:0043549 117 0.016
reproductive process GO:0022414 372 0.016
calcium ion transport GO:0006816 131 0.016
cellular response to cytokine stimulus GO:0071345 127 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
axonogenesis GO:0007409 71 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
response to purine containing compound GO:0014074 126 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
regulation of secretion GO:0051046 224 0.016
response to ethanol GO:0045471 162 0.015
reproduction GO:0000003 245 0.015
peptidyl tyrosine modification GO:0018212 72 0.015
cell type specific apoptotic process GO:0097285 134 0.015
muscle system process GO:0003012 115 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
positive regulation of transferase activity GO:0051347 81 0.015
carbohydrate metabolic process GO:0005975 130 0.015
peptidyl tyrosine phosphorylation GO:0018108 72 0.015
cell part morphogenesis GO:0032990 123 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
regulation of body fluid levels GO:0050878 90 0.015
regulation of nervous system development GO:0051960 264 0.015
cellular response to steroid hormone stimulus GO:0071383 93 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
ribonucleotide catabolic process GO:0009261 136 0.015
reproductive structure development GO:0048608 128 0.015
response to decreased oxygen levels GO:0036293 237 0.015
purine containing compound catabolic process GO:0072523 138 0.014
single organism reproductive process GO:0044702 297 0.014
axis specification GO:0009798 4 0.014
regulation of neuron differentiation GO:0045664 208 0.014
regulation of transmembrane transport GO:0034762 122 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
response to glucose GO:0009749 136 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
response to nutrient GO:0007584 248 0.014
multicellular organismal signaling GO:0035637 44 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
regulation of mapk cascade GO:0043408 116 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
cellular lipid metabolic process GO:0044255 208 0.014
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
regulation of proteasomal protein catabolic process GO:0061136 4 0.014
reactive oxygen species metabolic process GO:0072593 37 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
non canonical wnt signaling pathway GO:0035567 3 0.013
cell adhesion GO:0007155 110 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.013
regulation of protein localization GO:0032880 81 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
wound healing GO:0042060 122 0.013
behavior GO:0007610 205 0.013
regulation of blood vessel size GO:0050880 89 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
response to ketone GO:1901654 182 0.013
positive regulation of secretion GO:0051047 140 0.013
cellular response to lipid GO:0071396 201 0.013
muscle structure development GO:0061061 87 0.013
meiotic cell cycle process GO:1903046 3 0.012
heart morphogenesis GO:0003007 3 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
regulation of immune system process GO:0002682 123 0.012
response to glucocorticoid GO:0051384 223 0.012
regulation of protein kinase activity GO:0045859 105 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
multi organism reproductive process GO:0044703 262 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
gland development GO:0048732 155 0.012
positive regulation of multicellular organismal process GO:0051240 387 0.012
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.012
regulation of hormone levels GO:0010817 187 0.012
nucleoside metabolic process GO:0009116 179 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
calcium ion homeostasis GO:0055074 162 0.012
regulation of secretion by cell GO:1903530 208 0.012
mapk cascade GO:0000165 140 0.012
positive regulation of signal transduction GO:0009967 175 0.012
Fly
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
response to camp GO:0051591 91 0.012
cell cell signaling GO:0007267 335 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
hematopoietic progenitor cell differentiation GO:0002244 2 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
transmission of nerve impulse GO:0019226 42 0.011
response to growth factor GO:0070848 189 0.011
cell cycle process GO:0022402 57 0.011
aging GO:0007568 241 0.011
Worm
regulation of blood circulation GO:1903522 110 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
small molecule biosynthetic process GO:0044283 124 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
urogenital system development GO:0001655 78 0.011
regulation of hydrolase activity GO:0051336 143 0.011
response to carbohydrate GO:0009743 183 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
action potential GO:0001508 54 0.011
response to toxic substance GO:0009636 133 0.011
regulation of tube size GO:0035150 89 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
growth GO:0040007 165 0.011
Fly
ras protein signal transduction GO:0007265 29 0.011
organophosphate catabolic process GO:0046434 148 0.011
cell migration GO:0016477 197 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
regulation of catabolic process GO:0009894 113 0.011
establishment of tissue polarity GO:0007164 2 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
response to other organism GO:0051707 220 0.011
peptide biosynthetic process GO:0043043 3 0.011
regulation of cellular localization GO:0060341 263 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.010
multi multicellular organism process GO:0044706 138 0.010
nucleoside phosphate catabolic process GO:1901292 140 0.010
lipid transport GO:0006869 61 0.010
morphogenesis of a polarized epithelium GO:0001738 1 0.010
protein localization GO:0008104 191 0.010
single organism behavior GO:0044708 130 0.010
cardiovascular system development GO:0072358 134 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
regulation of cell projection organization GO:0031344 175 0.010
response to bacterium GO:0009617 200 0.010
positive regulation of cell development GO:0010720 176 0.010
regulation of neurogenesis GO:0050767 247 0.010
response to corticosteroid GO:0031960 235 0.010
response to acid chemical GO:0001101 222 0.010
regulation of muscle system process GO:0090257 79 0.010

Hipk4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.053
nervous system disease DOID:863 0 0.053
sensory system disease DOID:0050155 0 0.021
eye and adnexa disease DOID:1492 0 0.021
eye disease DOID:5614 0 0.021
retinal disease DOID:5679 0 0.015
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012
musculoskeletal system disease DOID:17 0 0.010