Rattus norvegicus

0 known processes

Dpep2

dipeptidase 2

Dpep2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
rna biosynthetic process GO:0032774 380 0.136
negative regulation of metabolic process GO:0009892 331 0.110
cell motility GO:0048870 202 0.108
rna metabolic process GO:0016070 406 0.103
regulation of rna biosynthetic process GO:2001141 381 0.101
transcription dna templated GO:0006351 377 0.095
positive regulation of cell proliferation GO:0008284 249 0.093
regulation of rna metabolic process GO:0051252 391 0.090
regulation of nucleic acid templated transcription GO:1903506 380 0.087
regulation of transcription dna templated GO:0006355 374 0.081
intracellular signal transduction GO:0035556 314 0.079
localization of cell GO:0051674 202 0.078
transcription from rna polymerase ii promoter GO:0006366 252 0.076
cell migration GO:0016477 197 0.073
nucleic acid templated transcription GO:0097659 379 0.072
positive regulation of gene expression GO:0010628 244 0.069
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.068
regulation of cell motility GO:2000145 131 0.068
response to inorganic substance GO:0010035 377 0.066
regulation of molecular function GO:0065009 398 0.066
positive regulation of rna metabolic process GO:0051254 203 0.065
negative regulation of gene expression GO:0010629 199 0.064
carboxylic acid metabolic process GO:0019752 289 0.061
organic acid metabolic process GO:0006082 292 0.060
regulation of signal transduction GO:0009966 318 0.060
negative regulation of multicellular organismal process GO:0051241 203 0.055
positive regulation of nucleic acid templated transcription GO:1903508 197 0.055
cellular component movement GO:0006928 248 0.055
immune system process GO:0002376 204 0.054
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.053
positive regulation of rna biosynthetic process GO:1902680 197 0.052
cellular response to lipid GO:0071396 201 0.051
programmed cell death GO:0012501 392 0.051
regulation of cell proliferation GO:0042127 359 0.051
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.050
positive regulation of transcription dna templated GO:0045893 197 0.050
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.049
regulation of hydrolase activity GO:0051336 143 0.048
regulation of programmed cell death GO:0043067 341 0.048
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.047
macromolecule localization GO:0033036 252 0.046
negative regulation of macromolecule metabolic process GO:0010605 260 0.046
regulation of phosphorus metabolic process GO:0051174 349 0.045
negative regulation of cellular metabolic process GO:0031324 281 0.044
regulation of phosphate metabolic process GO:0019220 349 0.044
negative regulation of apoptotic process GO:0043066 181 0.043
regulation of cell differentiation GO:0045595 320 0.043
oxoacid metabolic process GO:0043436 290 0.042
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.042
negative regulation of cellular biosynthetic process GO:0031327 161 0.042
response to hypoxia GO:0001666 231 0.042
regulation of locomotion GO:0040012 148 0.041
regulation of cell migration GO:0030334 128 0.041
aging GO:0007568 241 0.040
regulation of cellular protein metabolic process GO:0032268 267 0.040
positive regulation of transport GO:0051050 245 0.040
response to acid chemical GO:0001101 222 0.039
regulation of immune system process GO:0002682 123 0.037
regulation of apoptotic process GO:0042981 335 0.037
cellular catabolic process GO:0044248 295 0.036
positive regulation of molecular function GO:0044093 230 0.036
cytokine mediated signaling pathway GO:0019221 43 0.036
central nervous system development GO:0007417 311 0.036
secretion by cell GO:0032940 248 0.035
negative regulation of rna metabolic process GO:0051253 123 0.035
response to oxygen levels GO:0070482 265 0.035
regulation of catalytic activity GO:0050790 304 0.035
response to peptide hormone GO:0043434 278 0.034
organic substance catabolic process GO:1901575 316 0.034
positive regulation of programmed cell death GO:0043068 157 0.034
positive regulation of cellular biosynthetic process GO:0031328 295 0.033
anatomical structure morphogenesis GO:0009653 298 0.033
nucleoside phosphate metabolic process GO:0006753 283 0.032
cellular amino acid metabolic process GO:0006520 107 0.032
regulation of multicellular organismal development GO:2000026 376 0.032
anatomical structure formation involved in morphogenesis GO:0048646 83 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.031
lipid metabolic process GO:0006629 283 0.031
cell cell signaling GO:0007267 335 0.031
protein localization GO:0008104 191 0.031
positive regulation of cell death GO:0010942 184 0.031
regulation of cellular localization GO:0060341 263 0.030
proteolysis GO:0006508 175 0.030
Mouse
positive regulation of cellular component movement GO:0051272 102 0.030
negative regulation of nucleic acid templated transcription GO:1903507 117 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
tissue development GO:0009888 252 0.029
protein phosphorylation GO:0006468 345 0.029
regulation of secretion GO:0051046 224 0.029
cellular ketone metabolic process GO:0042180 51 0.028
ribonucleotide metabolic process GO:0009259 231 0.028
catabolic process GO:0009056 351 0.028
wound healing GO:0042060 122 0.028
negative regulation of biosynthetic process GO:0009890 168 0.028
negative regulation of programmed cell death GO:0043069 183 0.028
positive regulation of phosphorus metabolic process GO:0010562 262 0.028
regulation of nervous system development GO:0051960 264 0.027
regulation of cellular component movement GO:0051270 150 0.027
regulation of cellular component organization GO:0051128 368 0.027
negative regulation of cell death GO:0060548 229 0.027
response to extracellular stimulus GO:0009991 380 0.027
cellular response to hormone stimulus GO:0032870 247 0.027
secretion GO:0046903 307 0.027
apoptotic process GO:0006915 381 0.027
biological adhesion GO:0022610 110 0.027
metal ion homeostasis GO:0055065 186 0.027
response to nutrient GO:0007584 248 0.026
defense response GO:0006952 194 0.026
negative regulation of rna biosynthetic process GO:1902679 118 0.026
response to wounding GO:0009611 254 0.026
metal ion transport GO:0030001 289 0.026
regulation of leukocyte activation GO:0002694 45 0.026
response to peptide GO:1901652 292 0.025
positive regulation of nervous system development GO:0051962 178 0.025
positive regulation of cellular amine metabolic process GO:0033240 3 0.025
vesicle mediated transport GO:0016192 181 0.024
cation transport GO:0006812 382 0.024
regulation of phosphorylation GO:0042325 248 0.024
regulation of neurogenesis GO:0050767 247 0.024
response to metal ion GO:0010038 253 0.024
limb morphogenesis GO:0035108 4 0.024
positive regulation of locomotion GO:0040017 102 0.024
cellular homeostasis GO:0019725 252 0.024
immune response GO:0006955 104 0.024
head development GO:0060322 247 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
purine containing compound metabolic process GO:0072521 253 0.023
response to decreased oxygen levels GO:0036293 237 0.023
positive regulation of phosphate metabolic process GO:0045937 262 0.023
response to estrogen GO:0043627 232 0.023
regulation of protein metabolic process GO:0051246 289 0.023
ion transmembrane transport GO:0034220 365 0.023
response to nutrient levels GO:0031667 370 0.023
cellular amine metabolic process GO:0044106 38 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
organophosphate metabolic process GO:0019637 370 0.023
regulation of response to stress GO:0080134 126 0.023
circulatory system development GO:0072359 134 0.022
cation homeostasis GO:0055080 195 0.022
nucleotide metabolic process GO:0009117 279 0.022
negative regulation of transcription dna templated GO:0045892 116 0.022
amine metabolic process GO:0009308 38 0.022
cellular chemical homeostasis GO:0055082 247 0.022
cellular component biogenesis GO:0044085 368 0.022
regulation of secretion by cell GO:1903530 208 0.021
establishment of protein localization GO:0045184 141 0.021
reproduction GO:0000003 245 0.021
cardiovascular system development GO:0072358 134 0.021
negative regulation of cell proliferation GO:0008285 119 0.021
positive regulation of developmental process GO:0051094 283 0.021
positive regulation of cell migration GO:0030335 96 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
negative regulation of secretion by cell GO:1903531 72 0.020
sexual reproduction GO:0019953 148 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
cellular macromolecule localization GO:0070727 122 0.020
single organism catabolic process GO:0044712 283 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
homeostatic process GO:0042592 331 0.020
positive regulation of cell communication GO:0010647 271 0.020
multicellular organism reproduction GO:0032504 233 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
response to growth factor GO:0070848 189 0.020
organic hydroxy compound metabolic process GO:1901615 115 0.020
ion homeostasis GO:0050801 212 0.019
response to bacterium GO:0009617 200 0.019
organelle organization GO:0006996 266 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
g protein coupled receptor signaling pathway GO:0007186 242 0.019
regulation of cell activation GO:0050865 50 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
response to monosaccharide GO:0034284 159 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
intracellular transport GO:0046907 185 0.019
positive regulation of immune system process GO:0002684 90 0.019
salivary gland development GO:0007431 3 0.019
cellular response to oxygen containing compound GO:1901701 386 0.019
cellular response to growth factor stimulus GO:0071363 162 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
response to external biotic stimulus GO:0043207 221 0.018
regulation of anatomical structure morphogenesis GO:0022603 141 0.018
neuron differentiation GO:0030182 368 0.018
cell projection organization GO:0030030 302 0.018
regulation of cell development GO:0060284 263 0.018
macromolecular complex assembly GO:0065003 273 0.018
positive regulation of cell motility GO:2000147 97 0.018
response to corticosteroid GO:0031960 235 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
endocytosis GO:0006897 84 0.018
negative regulation of cell communication GO:0010648 158 0.017
multi organism reproductive process GO:0044703 262 0.017
regeneration GO:0031099 163 0.017
response to other organism GO:0051707 220 0.017
positive regulation of apoptotic process GO:0043065 154 0.017
cellular ion homeostasis GO:0006873 184 0.017
vasculature development GO:0001944 70 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
cellular component assembly GO:0022607 360 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
response to carbohydrate GO:0009743 183 0.017
divalent inorganic cation transport GO:0072511 134 0.017
negative regulation of signaling GO:0023057 157 0.017
cellular response to endogenous stimulus GO:0071495 377 0.017
negative regulation of transport GO:0051051 136 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.017
response to mechanical stimulus GO:0009612 134 0.017
regulation of hormone levels GO:0010817 187 0.017
response to hexose GO:0009746 144 0.016
positive regulation of cell development GO:0010720 176 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
locomotion GO:0040011 237 0.016
negative regulation of secretion GO:0051048 82 0.016
response to amino acid GO:0043200 75 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
cellular response to glucocorticoid stimulus GO:0071385 68 0.016
organ regeneration GO:0031100 101 0.016
angiogenesis GO:0001525 53 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
reproductive process GO:0022414 372 0.016
response to glucose GO:0009749 136 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
negative regulation of developmental process GO:0051093 125 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
cellular response to biotic stimulus GO:0071216 59 0.016
growth GO:0040007 165 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
chemical homeostasis GO:0048878 292 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
regulation of vesicle mediated transport GO:0060627 81 0.015
cell activation GO:0001775 97 0.015
response to alkaloid GO:0043279 132 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
regulation of protein modification process GO:0031399 194 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
divalent metal ion transport GO:0070838 132 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
signal transduction by phosphorylation GO:0023014 144 0.014
behavior GO:0007610 205 0.014
positive regulation of angiogenesis GO:0045766 28 0.014
cellular response to molecule of bacterial origin GO:0071219 56 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
positive regulation of protein modification process GO:0031401 142 0.014
response to temperature stimulus GO:0009266 94 0.014
single organism biosynthetic process GO:0044711 342 0.014
response to biotic stimulus GO:0009607 226 0.014
single organism reproductive process GO:0044702 297 0.014
protein heterooligomerization GO:0051291 89 0.014
brain development GO:0007420 247 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
calcium ion homeostasis GO:0055074 162 0.014
positive regulation of cell activation GO:0050867 34 0.014
small molecule biosynthetic process GO:0044283 124 0.014
cytoplasmic transport GO:0016482 115 0.014
reactive oxygen species metabolic process GO:0072593 37 0.014
calcium ion transport GO:0006816 131 0.014
negative regulation of signal transduction GO:0009968 83 0.013
response to hyperoxia GO:0055093 45 0.013
response to glucocorticoid GO:0051384 223 0.013
protein complex assembly GO:0006461 263 0.013
regulation of lymphocyte migration GO:2000401 1 0.013
mapk cascade GO:0000165 140 0.013
response to insulin GO:0032868 133 0.013
regulation of metal ion transport GO:0010959 118 0.013
cellular protein localization GO:0034613 122 0.013
regulation of endocytosis GO:0030100 42 0.013
regulation of ion transport GO:0043269 245 0.013
sequestering of calcium ion GO:0051208 8 0.013
inflammatory response GO:0006954 150 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
protein complex subunit organization GO:0071822 302 0.013
sequestering of metal ion GO:0051238 9 0.013
regulation of neuron projection development GO:0010975 161 0.013
carbohydrate metabolic process GO:0005975 130 0.013
synaptic transmission GO:0007268 235 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
cell adhesion GO:0007155 110 0.013
regulation of endothelial cell differentiation GO:0045601 4 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
gonad development GO:0008406 104 0.012
regulation of protein localization GO:0032880 81 0.012
cellular response to steroid hormone stimulus GO:0071383 93 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
ras protein signal transduction GO:0007265 29 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
maintenance of location GO:0051235 17 0.012
regulation of vasculature development GO:1901342 44 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
dna metabolic process GO:0006259 96 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
positive regulation of leukocyte activation GO:0002696 30 0.012
cellular cation homeostasis GO:0030003 180 0.012
response to reactive oxygen species GO:0000302 120 0.012
regulation of response to external stimulus GO:0032101 106 0.012
cellular response to acid chemical GO:0071229 75 0.012
positive regulation of endothelial cell migration GO:0010595 4 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
pseudopodium organization GO:0031268 3 0.012
protein complex biogenesis GO:0070271 263 0.012
mesenchymal cell proliferation GO:0010463 4 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
regulation of cell adhesion GO:0030155 52 0.012
smooth muscle cell proliferation GO:0048659 77 0.012
protein oligomerization GO:0051259 191 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
regulation of cell projection organization GO:0031344 175 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
regulation of system process GO:0044057 208 0.012
regulation of cytokine biosynthetic process GO:0042035 3 0.012
taxis GO:0042330 67 0.012
gliogenesis GO:0042063 93 0.012
cytokine biosynthetic process GO:0042089 3 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
response to toxic substance GO:0009636 133 0.011
single organism intracellular transport GO:1902582 166 0.011
neuron projection development GO:0031175 273 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
gastrulation GO:0007369 2 0.011
sensory perception GO:0007600 101 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
peptidyl amino acid modification GO:0018193 126 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
response to retinoic acid GO:0032526 63 0.011
innate immune response GO:0045087 35 0.011
regulation of transferase activity GO:0051338 123 0.011
glomerular mesangial cell proliferation GO:0072110 4 0.011
muscle cell proliferation GO:0033002 84 0.011
response to ketone GO:1901654 182 0.011
eye morphogenesis GO:0048592 4 0.011
chemotaxis GO:0006935 66 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
development of primary sexual characteristics GO:0045137 107 0.011
salivary gland morphogenesis GO:0007435 1 0.010
regulation of t cell migration GO:2000404 1 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
cellular response to abiotic stimulus GO:0071214 85 0.010
multicellular organism growth GO:0035264 1 0.010
lipid storage GO:0019915 1 0.010
regulation of muscle system process GO:0090257 79 0.010
renal system development GO:0072001 67 0.010
blood circulation GO:0008015 183 0.010
neurological system process GO:0050877 219 0.010
cellular response to peptide hormone stimulus GO:0071375 120 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
blood vessel morphogenesis GO:0048514 58 0.010
response to lipopolysaccharide GO:0032496 191 0.010
single organism organelle organization GO:1902589 180 0.010
negative regulation of innate immune response GO:0045824 4 0.010
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.010
sensory perception of pain GO:0019233 73 0.010

Dpep2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
musculoskeletal system disease DOID:17 0 0.017
nervous system disease DOID:863 0 0.015