Rattus norvegicus

0 known processes

Osm

oncostatin M

Osm biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to endogenous stimulus GO:0071495 377 0.060
organic acid metabolic process GO:0006082 292 0.057
regulation of rna biosynthetic process GO:2001141 381 0.057
rna biosynthetic process GO:0032774 380 0.055
transcription dna templated GO:0006351 377 0.053
regulation of nucleic acid templated transcription GO:1903506 380 0.051
apoptotic process GO:0006915 381 0.051
carboxylic acid metabolic process GO:0019752 289 0.050
rna metabolic process GO:0016070 406 0.050
nucleic acid templated transcription GO:0097659 379 0.048
regulation of rna metabolic process GO:0051252 391 0.048
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.048
regulation of transcription dna templated GO:0006355 374 0.046
oxoacid metabolic process GO:0043436 290 0.046
regulation of apoptotic process GO:0042981 335 0.044
regulation of programmed cell death GO:0043067 341 0.044
regulation of cell proliferation GO:0042127 359 0.042
cation transport GO:0006812 382 0.042
response to inorganic substance GO:0010035 377 0.041
cellular response to oxygen containing compound GO:1901701 386 0.040
programmed cell death GO:0012501 392 0.040
cellular amino acid metabolic process GO:0006520 107 0.039
central nervous system development GO:0007417 311 0.039
anatomical structure morphogenesis GO:0009653 298 0.038
cellular component assembly GO:0022607 360 0.038
regulation of cellular component organization GO:0051128 368 0.037
protein phosphorylation GO:0006468 345 0.037
neuron differentiation GO:0030182 368 0.036
regulation of phosphorus metabolic process GO:0051174 349 0.035
intracellular signal transduction GO:0035556 314 0.035
transcription from rna polymerase ii promoter GO:0006366 252 0.035
regulation of multicellular organismal development GO:2000026 376 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.034
regulation of cellular amino acid metabolic process GO:0006521 2 0.034
response to oxygen levels GO:0070482 265 0.034
response to extracellular stimulus GO:0009991 380 0.033
positive regulation of cell proliferation GO:0008284 249 0.033
cellular amine metabolic process GO:0044106 38 0.033
positive regulation of multicellular organismal process GO:0051240 387 0.033
cellular ketone metabolic process GO:0042180 51 0.033
cell projection organization GO:0030030 302 0.033
response to nutrient levels GO:0031667 370 0.033
negative regulation of cellular metabolic process GO:0031324 281 0.032
macromolecular complex subunit organization GO:0043933 339 0.032
reproductive process GO:0022414 372 0.032
single organism reproductive process GO:0044702 297 0.031
amine metabolic process GO:0009308 38 0.031
regulation of cellular amine metabolic process GO:0033238 8 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
negative regulation of metabolic process GO:0009892 331 0.030
regulation of molecular function GO:0065009 398 0.030
cellular response to hormone stimulus GO:0032870 247 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.030
cellular component biogenesis GO:0044085 368 0.029
transmembrane transport GO:0055085 412 0.029
regulation of catalytic activity GO:0050790 304 0.029
response to hypoxia GO:0001666 231 0.029
homeostatic process GO:0042592 331 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.028
cellular response to organic cyclic compound GO:0071407 202 0.028
protein complex subunit organization GO:0071822 302 0.028
regulation of protein metabolic process GO:0051246 289 0.028
cellular component movement GO:0006928 248 0.028
positive regulation of gene expression GO:0010628 244 0.028
cellular response to stress GO:0033554 269 0.028
regulation of phosphate metabolic process GO:0019220 349 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.027
neuron projection development GO:0031175 273 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
positive regulation of response to stimulus GO:0048584 285 0.027
macromolecular complex assembly GO:0065003 273 0.027
single organism biosynthetic process GO:0044711 342 0.027
response to metal ion GO:0010038 253 0.027
response to decreased oxygen levels GO:0036293 237 0.027
brain development GO:0007420 247 0.027
chemical homeostasis GO:0048878 292 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
regulation of cell differentiation GO:0045595 320 0.026
catabolic process GO:0009056 351 0.026
cellular response to nitrogen compound GO:1901699 210 0.026
cellular homeostasis GO:0019725 252 0.026
cellular response to lipid GO:0071396 201 0.026
organelle organization GO:0006996 266 0.026
protein complex assembly GO:0006461 263 0.026
regulation of nervous system development GO:0051960 264 0.026
neurological system process GO:0050877 219 0.026
positive regulation of developmental process GO:0051094 283 0.025
protein complex biogenesis GO:0070271 263 0.025
negative regulation of cell death GO:0060548 229 0.025
response to peptide GO:1901652 292 0.025
organic substance catabolic process GO:1901575 316 0.025
multi organism reproductive process GO:0044703 262 0.025
negative regulation of programmed cell death GO:0043069 183 0.025
regulation of signal transduction GO:0009966 318 0.025
positive regulation of rna biosynthetic process GO:1902680 197 0.025
ion homeostasis GO:0050801 212 0.024
positive regulation of rna metabolic process GO:0051254 203 0.024
response to growth factor GO:0070848 189 0.024
positive regulation of molecular function GO:0044093 230 0.024
defense response GO:0006952 194 0.024
response to glucocorticoid GO:0051384 223 0.024
negative regulation of apoptotic process GO:0043066 181 0.024
metal ion transport GO:0030001 289 0.024
response to estrogen GO:0043627 232 0.024
secretion by cell GO:0032940 248 0.024
locomotion GO:0040011 237 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.023
regulation of protein modification process GO:0031399 194 0.023
neuron development GO:0048666 286 0.023
positive regulation of transcription dna templated GO:0045893 197 0.023
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
positive regulation of phosphate metabolic process GO:0045937 262 0.023
response to wounding GO:0009611 254 0.023
negative regulation of gene expression GO:0010629 199 0.023
localization of cell GO:0051674 202 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
g protein coupled receptor signaling pathway GO:0007186 242 0.022
cellular chemical homeostasis GO:0055082 247 0.022
head development GO:0060322 247 0.022
negative regulation of biosynthetic process GO:0009890 168 0.022
multicellular organism reproduction GO:0032504 233 0.022
secretion GO:0046903 307 0.022
response to acid chemical GO:0001101 222 0.022
regulation of phosphorylation GO:0042325 248 0.022
positive regulation of cell death GO:0010942 184 0.022
macromolecule localization GO:0033036 252 0.022
cellular metal ion homeostasis GO:0006875 172 0.022
response to corticosteroid GO:0031960 235 0.022
response to nutrient GO:0007584 248 0.022
organophosphate metabolic process GO:0019637 370 0.022
regulation of protein phosphorylation GO:0001932 183 0.021
response to ketone GO:1901654 182 0.021
reproduction GO:0000003 245 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
positive regulation of signaling GO:0023056 270 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
regulation of neurogenesis GO:0050767 247 0.021
cellular response to growth factor stimulus GO:0071363 162 0.021
cation homeostasis GO:0055080 195 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
protein oligomerization GO:0051259 191 0.021
regulation of cell development GO:0060284 263 0.021
regulation of intracellular signal transduction GO:1902531 218 0.021
response to carbohydrate GO:0009743 183 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.020
negative regulation of cell communication GO:0010648 158 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
nitrogen compound transport GO:0071705 229 0.020
cell motility GO:0048870 202 0.020
regulation of secretion by cell GO:1903530 208 0.020
cellular catabolic process GO:0044248 295 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
cell cell signaling GO:0007267 335 0.020
circulatory system process GO:0003013 183 0.020
regulation of ion transport GO:0043269 245 0.020
lipid metabolic process GO:0006629 283 0.020
immune system process GO:0002376 204 0.020
response to peptide hormone GO:0043434 278 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
cell migration GO:0016477 197 0.020
positive regulation of cell communication GO:0010647 271 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
cellular ion homeostasis GO:0006873 184 0.020
cellular response to organonitrogen compound GO:0071417 197 0.020
positive regulation of phosphorylation GO:0042327 177 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
metal ion homeostasis GO:0055065 186 0.019
positive regulation of transport GO:0051050 245 0.019
ion transmembrane transport GO:0034220 365 0.019
divalent inorganic cation homeostasis GO:0072507 165 0.019
growth GO:0040007 165 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.019
regulation of system process GO:0044057 208 0.019
positive regulation of protein modification process GO:0031401 142 0.019
regeneration GO:0031099 163 0.019
regulation of cellular localization GO:0060341 263 0.019
intracellular transport GO:0046907 185 0.019
response to cytokine GO:0034097 215 0.019
single organism catabolic process GO:0044712 283 0.019
blood circulation GO:0008015 183 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
cellular cation homeostasis GO:0030003 180 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
aging GO:0007568 241 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.019
response to radiation GO:0009314 137 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
cellular calcium ion homeostasis GO:0006874 160 0.018
calcium ion transport GO:0006816 131 0.018
positive regulation of nervous system development GO:0051962 178 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
tissue development GO:0009888 252 0.018
cellular component morphogenesis GO:0032989 155 0.018
regulation of anatomical structure morphogenesis GO:0022603 141 0.018
response to estradiol GO:0032355 164 0.018
response to biotic stimulus GO:0009607 226 0.018
negative regulation of response to stimulus GO:0048585 155 0.017
purine containing compound metabolic process GO:0072521 253 0.017
positive regulation of apoptotic process GO:0043065 154 0.017
calcium ion homeostasis GO:0055074 162 0.017
regulation of neuron differentiation GO:0045664 208 0.017
nucleotide metabolic process GO:0009117 279 0.017
anterior posterior pattern specification GO:0009952 1 0.017
positive regulation of cell development GO:0010720 176 0.017
response to external biotic stimulus GO:0043207 221 0.017
response to monosaccharide GO:0034284 159 0.017
cellular lipid metabolic process GO:0044255 208 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
cation transmembrane transport GO:0098655 263 0.017
single organism organelle organization GO:1902589 180 0.017
negative regulation of nucleic acid templated transcription GO:1903507 117 0.017
synaptic transmission GO:0007268 235 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
behavior GO:0007610 205 0.016
protein localization GO:0008104 191 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
regulation of immune system process GO:0002682 123 0.016
negative regulation of rna metabolic process GO:0051253 123 0.016
monovalent inorganic cation transport GO:0015672 172 0.016
negative regulation of rna biosynthetic process GO:1902679 118 0.016
regulation of canonical wnt signaling pathway GO:0060828 4 0.016
cellular response to external stimulus GO:0071496 118 0.016
regulation of anatomical structure size GO:0090066 135 0.016
inflammatory response GO:0006954 150 0.016
response to hexose GO:0009746 144 0.016
female pregnancy GO:0007565 122 0.016
multi multicellular organism process GO:0044706 138 0.016
axis specification GO:0009798 4 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
reproductive system development GO:0061458 128 0.016
response to bacterium GO:0009617 200 0.016
regulation of cell projection organization GO:0031344 175 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
regulation of response to stress GO:0080134 126 0.016
regulation of membrane potential GO:0042391 110 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
regulation of secretion GO:0051046 224 0.015
gland development GO:0048732 155 0.015
sexual reproduction GO:0019953 148 0.015
divalent metal ion transport GO:0070838 132 0.015
reproductive structure development GO:0048608 128 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
circulatory system development GO:0072359 134 0.015
response to other organism GO:0051707 220 0.015
wound healing GO:0042060 122 0.015
response to vitamin GO:0033273 131 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
muscle system process GO:0003012 115 0.015
negative regulation of transport GO:0051051 136 0.015
cell projection morphogenesis GO:0048858 123 0.015
regulation of locomotion GO:0040012 148 0.015
divalent inorganic cation transport GO:0072511 134 0.015
cell growth GO:0016049 104 0.015
ras protein signal transduction GO:0007265 29 0.015
cell type specific apoptotic process GO:0097285 134 0.015
gamete generation GO:0007276 124 0.015
negative regulation of molecular function GO:0044092 133 0.015
proteolysis GO:0006508 175 0.015
response to toxic substance GO:0009636 133 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
cell adhesion GO:0007155 110 0.014
establishment of protein localization GO:0045184 141 0.014
response to glucose GO:0009749 136 0.014
cell morphogenesis GO:0000902 142 0.014
signal release GO:0023061 145 0.014
protein transport GO:0015031 132 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
biological adhesion GO:0022610 110 0.014
negative regulation of signaling GO:0023057 157 0.014
response to oxidative stress GO:0006979 186 0.014
sensory perception GO:0007600 101 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
single organism intracellular transport GO:1902582 166 0.014
cellular protein localization GO:0034613 122 0.014
developmental growth GO:0048589 100 0.014
regulation of hydrolase activity GO:0051336 143 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
developmental process involved in reproduction GO:0003006 159 0.014
response to ethanol GO:0045471 162 0.014
regulation of cell motility GO:2000145 131 0.014
lipid biosynthetic process GO:0008610 128 0.014
regulation of neuron projection development GO:0010975 161 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
nucleoside metabolic process GO:0009116 179 0.014
mapk cascade GO:0000165 140 0.014
multicellular organismal signaling GO:0035637 44 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
regulation of transferase activity GO:0051338 123 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
regulation of cellular component movement GO:0051270 150 0.013
response to mechanical stimulus GO:0009612 134 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
cellular response to peptide GO:1901653 133 0.013
oxidation reduction process GO:0055114 304 0.013
regulation of hormone levels GO:0010817 187 0.013
cell part morphogenesis GO:0032990 123 0.013
anion transport GO:0006820 178 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
regulation of neuron death GO:1901214 115 0.013
positive regulation of signal transduction GO:0009967 175 0.013
rhythmic process GO:0048511 156 0.013
heterocycle catabolic process GO:0046700 167 0.013
cardiovascular system development GO:0072358 134 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
non canonical wnt signaling pathway GO:0035567 3 0.013
regulation of metal ion transport GO:0010959 118 0.013
peptidyl amino acid modification GO:0018193 126 0.013
cellular response to alcohol GO:0097306 87 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
cellular response to steroid hormone stimulus GO:0071383 93 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
response to reactive oxygen species GO:0000302 120 0.013
inorganic cation transmembrane transport GO:0098662 202 0.013
aromatic compound catabolic process GO:0019439 168 0.013
negative regulation of developmental process GO:0051093 125 0.013
immune response GO:0006955 104 0.013
positive regulation of secretion GO:0051047 140 0.013
regulation of kinase activity GO:0043549 117 0.012
muscle contraction GO:0006936 88 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
regulation of cell migration GO:0030334 128 0.012
dna metabolic process GO:0006259 96 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
cellular macromolecule localization GO:0070727 122 0.012
regulation of body fluid levels GO:0050878 90 0.012
regulation of synaptic transmission GO:0050804 141 0.012
regulation of mapk cascade GO:0043408 116 0.012
gastrulation GO:0007369 2 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
single organism behavior GO:0044708 130 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
negative regulation of innate immune response GO:0045824 4 0.012
action potential GO:0001508 54 0.012
cell activation GO:0001775 97 0.012
regulation of cell growth GO:0001558 85 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
regulation of protein kinase activity GO:0045859 105 0.012
heart morphogenesis GO:0003007 3 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
neuron death GO:0070997 127 0.012
embryonic pattern specification GO:0009880 1 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
organ regeneration GO:0031100 101 0.012
hormone secretion GO:0046879 115 0.012
regulation of growth GO:0040008 105 0.012
regulation of muscle system process GO:0090257 79 0.012
regulation of blood circulation GO:1903522 110 0.012
response to lipopolysaccharide GO:0032496 191 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
spindle organization GO:0007051 2 0.012
negative regulation of signal transduction GO:0009968 83 0.012
establishment of tissue polarity GO:0007164 2 0.012
response to insulin GO:0032868 133 0.012
hematopoietic progenitor cell differentiation GO:0002244 2 0.012
chromosome segregation GO:0007059 2 0.011
cytoplasmic transport GO:0016482 115 0.011
carbohydrate metabolic process GO:0005975 130 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
positive regulation of immune system process GO:0002684 90 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
regulation of hormone secretion GO:0046883 106 0.011
hormone transport GO:0009914 121 0.011
cellular response to acid chemical GO:0071229 75 0.011
regulation of response to external stimulus GO:0032101 106 0.011
neuronal action potential GO:0019228 35 0.011
vascular process in circulatory system GO:0003018 96 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
eye morphogenesis GO:0048592 4 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
muscle structure development GO:0061061 87 0.011
urogenital system development GO:0001655 78 0.011
transmission of nerve impulse GO:0019226 42 0.011
regulation of calcium ion transport GO:0051924 77 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
vesicle mediated transport GO:0016192 181 0.011
regulation of peptide transport GO:0090087 87 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
neuron projection morphogenesis GO:0048812 122 0.011
membrane organization GO:0061024 94 0.011
regulation of catabolic process GO:0009894 113 0.011
male gamete generation GO:0048232 99 0.011
regulation of tube size GO:0035150 89 0.011
response to alkaloid GO:0043279 132 0.011
actin filament based process GO:0030029 86 0.011
spermatogenesis GO:0007283 99 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
nucleotide catabolic process GO:0009166 139 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010
synaptic growth at neuromuscular junction GO:0051124 1 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.010
glycosyl compound catabolic process GO:1901658 126 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.010
coenzyme metabolic process GO:0006732 86 0.010
ribonucleoside metabolic process GO:0009119 174 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
gliogenesis GO:0042063 93 0.010
sequestering of metal ion GO:0051238 9 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
response to activity GO:0014823 73 0.010
chemosensory behavior GO:0007635 2 0.010
response to retinoic acid GO:0032526 63 0.010
salivary gland development GO:0007431 3 0.010
tube development GO:0035295 89 0.010
hepaticobiliary system development GO:0061008 90 0.010
organ formation GO:0048645 3 0.010
response to purine containing compound GO:0014074 126 0.010
forebrain development GO:0030900 98 0.010
negative regulation of secretion GO:0051048 82 0.010
cofactor metabolic process GO:0051186 95 0.010
embryonic appendage morphogenesis GO:0035113 4 0.010
sequestering of calcium ion GO:0051208 8 0.010
purine nucleotide catabolic process GO:0006195 136 0.010

Osm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.036
musculoskeletal system disease DOID:17 0 0.018
sensory system disease DOID:0050155 0 0.017
central nervous system disease DOID:331 0 0.015
eye and adnexa disease DOID:1492 0 0.014
disease of metabolism DOID:0014667 0 0.014
eye disease DOID:5614 0 0.013
retinal disease DOID:5679 0 0.012
cardiovascular system disease DOID:1287 0 0.011
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010