Rattus norvegicus

143 known processes

Egln1

EGL nine homolog 1 (C. elegans)

(Aliases: HPH-2,HIF-PH2,PHD-2)

Egln1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to extracellular stimulus GO:0009991 380 0.052
regulation of cellular localization GO:0060341 263 0.047
rna metabolic process GO:0016070 406 0.046
regulation of nucleic acid templated transcription GO:1903506 380 0.044
carbohydrate derivative metabolic process GO:1901135 346 0.041
response to nutrient levels GO:0031667 370 0.040
apoptotic process GO:0006915 381 0.040
regulation of rna metabolic process GO:0051252 391 0.038
action potential GO:0001508 54 0.037
ion transmembrane transport GO:0034220 365 0.037
cation transport GO:0006812 382 0.037
regulation of transcription dna templated GO:0006355 374 0.036
negative regulation of metabolic process GO:0009892 331 0.036
g protein coupled receptor signaling pathway GO:0007186 242 0.035
cellular component biogenesis GO:0044085 368 0.035
cellular ketone metabolic process GO:0042180 51 0.035
response to peptide hormone GO:0043434 278 0.034
response to peptide GO:1901652 292 0.032
homeostatic process GO:0042592 331 0.032
Human
organic acid metabolic process GO:0006082 292 0.031
Human
regulation of cell proliferation GO:0042127 359 0.031
Rat
catabolic process GO:0009056 351 0.031
positive regulation of response to stimulus GO:0048584 285 0.031
macromolecular complex assembly GO:0065003 273 0.030
regulation of rna biosynthetic process GO:2001141 381 0.030
regulation of molecular function GO:0065009 398 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
transmembrane transport GO:0055085 412 0.030
cell cell signaling GO:0007267 335 0.030
cellular component assembly GO:0022607 360 0.030
regulation of cellular ketone metabolic process GO:0010565 27 0.029
protein complex subunit organization GO:0071822 302 0.029
transcription dna templated GO:0006351 377 0.028
neuronal action potential GO:0019228 35 0.028
response to carbohydrate GO:0009743 183 0.028
macromolecular complex subunit organization GO:0043933 339 0.028
cellular response to oxygen containing compound GO:1901701 386 0.028
nucleic acid templated transcription GO:0097659 379 0.028
chemical homeostasis GO:0048878 292 0.027
Human
negative regulation of cellular metabolic process GO:0031324 281 0.027
response to hexose GO:0009746 144 0.027
rhythmic process GO:0048511 156 0.027
neurological system process GO:0050877 219 0.027
response to hypoxia GO:0001666 231 0.027
regulation of membrane potential GO:0042391 110 0.027
organic substance catabolic process GO:1901575 316 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
transmission of nerve impulse GO:0019226 42 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.026
aging GO:0007568 241 0.026
carboxylic acid metabolic process GO:0019752 289 0.026
Human
organophosphate metabolic process GO:0019637 370 0.025
rna biosynthetic process GO:0032774 380 0.025
ribose phosphate metabolic process GO:0019693 235 0.025
cellular homeostasis GO:0019725 252 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
single organism catabolic process GO:0044712 283 0.024
gland development GO:0048732 155 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.024
programmed cell death GO:0012501 392 0.024
neuron differentiation GO:0030182 368 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
central nervous system development GO:0007417 311 0.024
purine nucleotide metabolic process GO:0006163 229 0.024
positive regulation of signaling GO:0023056 270 0.024
response to glucocorticoid GO:0051384 223 0.023
anatomical structure morphogenesis GO:0009653 298 0.023
Mouse
positive regulation of signal transduction GO:0009967 175 0.023
intracellular signal transduction GO:0035556 314 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
single organism organelle organization GO:1902589 180 0.023
regulation of apoptotic process GO:0042981 335 0.022
cellular amine metabolic process GO:0044106 38 0.022
cellular catabolic process GO:0044248 295 0.022
secretion GO:0046903 307 0.022
regulation of catalytic activity GO:0050790 304 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
regulation of synaptic transmission GO:0050804 141 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
regulation of signal transduction GO:0009966 318 0.022
amine metabolic process GO:0009308 38 0.022
neuron projection development GO:0031175 273 0.022
response to glucose GO:0009749 136 0.022
regulation of neurogenesis GO:0050767 247 0.022
cellular amino acid metabolic process GO:0006520 107 0.021
Human
oxoacid metabolic process GO:0043436 290 0.021
Human
transcription from rna polymerase ii promoter GO:0006366 252 0.021
cellular ion homeostasis GO:0006873 184 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
positive regulation of rna biosynthetic process GO:1902680 197 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
nucleotide metabolic process GO:0009117 279 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
regulation of phosphate metabolic process GO:0019220 349 0.019
synaptic transmission GO:0007268 235 0.019
positive regulation of developmental process GO:0051094 283 0.019
regulation of cellular component organization GO:0051128 368 0.019
single organism behavior GO:0044708 130 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
single organism reproductive process GO:0044702 297 0.019
Mouse
brain development GO:0007420 247 0.019
regulation of neuron differentiation GO:0045664 208 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
developmental process involved in reproduction GO:0003006 159 0.018
Mouse
blood circulation GO:0008015 183 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
protein complex biogenesis GO:0070271 263 0.018
multicellular organismal signaling GO:0035637 44 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
multi organism reproductive process GO:0044703 262 0.018
positive regulation of molecular function GO:0044093 230 0.018
metal ion transport GO:0030001 289 0.018
cell projection organization GO:0030030 302 0.018
response to nutrient GO:0007584 248 0.018
single organism biosynthetic process GO:0044711 342 0.018
reproductive process GO:0022414 372 0.018
Mouse
response to oxygen levels GO:0070482 265 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
ensheathment of neurons GO:0007272 40 0.018
positive regulation of protein modification process GO:0031401 142 0.018
regulation of protein metabolic process GO:0051246 289 0.018
circulatory system development GO:0072359 134 0.018
Mouse
tissue development GO:0009888 252 0.018
Mouse
regulation of cellular protein metabolic process GO:0032268 267 0.018
macromolecule localization GO:0033036 252 0.018
regulation of cell development GO:0060284 263 0.018
cell growth GO:0016049 104 0.018
regulation of cell differentiation GO:0045595 320 0.018
positive regulation of gene expression GO:0010628 244 0.017
myelination GO:0042552 39 0.017
organelle organization GO:0006996 266 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
protein oligomerization GO:0051259 191 0.017
cation homeostasis GO:0055080 195 0.017
axis specification GO:0009798 4 0.017
regulation of system process GO:0044057 208 0.017
positive regulation of cell communication GO:0010647 271 0.017
negative regulation of cell communication GO:0010648 158 0.017
proteolysis GO:0006508 175 0.017
response to oxidative stress GO:0006979 186 0.017
Human
inorganic ion transmembrane transport GO:0098660 229 0.017
regulation of programmed cell death GO:0043067 341 0.017
regulation of nervous system development GO:0051960 264 0.017
protein heterooligomerization GO:0051291 89 0.017
organophosphate biosynthetic process GO:0090407 143 0.017
protein complex assembly GO:0006461 263 0.016
multicellular organism reproduction GO:0032504 233 0.016
muscle system process GO:0003012 115 0.016
carbohydrate derivative biosynthetic process GO:1901137 124 0.016
protein localization GO:0008104 191 0.016
neuron development GO:0048666 286 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
response to corticosteroid GO:0031960 235 0.016
negative regulation of transport GO:0051051 136 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
reproduction GO:0000003 245 0.016
response to decreased oxygen levels GO:0036293 237 0.016
purine containing compound metabolic process GO:0072521 253 0.016
calcium ion homeostasis GO:0055074 162 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
regulation of ion transport GO:0043269 245 0.015
response to ethanol GO:0045471 162 0.015
axon ensheathment GO:0008366 40 0.015
oxidation reduction process GO:0055114 304 0.015
ras protein signal transduction GO:0007265 29 0.015
lipid metabolic process GO:0006629 283 0.015
anterior posterior pattern specification GO:0009952 1 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
cellular chemical homeostasis GO:0055082 247 0.015
cellular response to external stimulus GO:0071496 118 0.015
single organism intracellular transport GO:1902582 166 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
embryonic pattern specification GO:0009880 1 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
cellular cation homeostasis GO:0030003 180 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
regulation of hormone levels GO:0010817 187 0.014
positive regulation of nervous system development GO:0051962 178 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
nucleoside metabolic process GO:0009116 179 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
negative regulation of cell death GO:0060548 229 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
cellular protein localization GO:0034613 122 0.014
vesicle mediated transport GO:0016192 181 0.014
response to estrogen GO:0043627 232 0.014
nitrogen compound transport GO:0071705 229 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
regulation of neuron projection development GO:0010975 161 0.014
negative regulation of molecular function GO:0044092 133 0.014
positive regulation of transport GO:0051050 245 0.014
response to external biotic stimulus GO:0043207 221 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
cellular response to peptide hormone stimulus GO:0071375 120 0.014
ion homeostasis GO:0050801 212 0.014
regulation of multicellular organismal development GO:2000026 376 0.014
Mouse
lipid biosynthetic process GO:0008610 128 0.014
regulation of muscle system process GO:0090257 79 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
positive regulation of cell development GO:0010720 176 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
cellular response to peptide GO:1901653 133 0.014
anion transport GO:0006820 178 0.014
response to inorganic substance GO:0010035 377 0.013
Human
divalent metal ion transport GO:0070838 132 0.013
cellular response to organic cyclic compound GO:0071407 202 0.013
response to insulin GO:0032868 133 0.013
circadian rhythm GO:0007623 88 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
response to estradiol GO:0032355 164 0.013
response to biotic stimulus GO:0009607 226 0.013
chromosome segregation GO:0007059 2 0.013
response to cytokine GO:0034097 215 0.013
sexual reproduction GO:0019953 148 0.013
positive regulation of ion transport GO:0043270 94 0.013
cellular response to endogenous stimulus GO:0071495 377 0.013
cellular component movement GO:0006928 248 0.013
head development GO:0060322 247 0.013
response to growth factor GO:0070848 189 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
cellular response to stress GO:0033554 269 0.013
negative regulation of signaling GO:0023057 157 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
regeneration GO:0031099 163 0.012
heterocycle catabolic process GO:0046700 167 0.012
cardiovascular system development GO:0072358 134 0.012
Mouse
cell morphogenesis GO:0000902 142 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
gastrulation GO:0007369 2 0.012
response to monosaccharide GO:0034284 159 0.012
muscle contraction GO:0006936 88 0.012
positive regulation of multicellular organismal process GO:0051240 387 0.012
carboxylic acid transport GO:0046942 115 0.012
regulation of cell projection organization GO:0031344 175 0.012
negative regulation of gene expression GO:0010629 199 0.012
multi multicellular organism process GO:0044706 138 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
regulation of phosphorus metabolic process GO:0051174 349 0.012
response to wounding GO:0009611 254 0.012
response to other organism GO:0051707 220 0.012
response to toxic substance GO:0009636 133 0.012
response to ketone GO:1901654 182 0.012
positive regulation of cell death GO:0010942 184 0.012
learning or memory GO:0007611 90 0.012
heart morphogenesis GO:0003007 3 0.012
Mouse
response to vitamin GO:0033273 131 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
cation transmembrane transport GO:0098655 263 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
protein phosphorylation GO:0006468 345 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
amide transport GO:0042886 105 0.012
cellular response to extracellular stimulus GO:0031668 73 0.011
defense response GO:0006952 194 0.011
response to acid chemical GO:0001101 222 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.011
growth GO:0040007 165 0.011
metal ion homeostasis GO:0055065 186 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
actin filament based process GO:0030029 86 0.011
response to purine containing compound GO:0014074 126 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
regulation of anatomical structure size GO:0090066 135 0.011
secretion by cell GO:0032940 248 0.011
female pregnancy GO:0007565 122 0.011
signal release GO:0023061 145 0.011
response to bacterium GO:0009617 200 0.011
axon development GO:0061564 96 0.011
response to organophosphorus GO:0046683 102 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
intracellular transport GO:0046907 185 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
glycosyl compound catabolic process GO:1901658 126 0.010
eye morphogenesis GO:0048592 4 0.010
cell type specific apoptotic process GO:0097285 134 0.010
establishment of protein localization GO:0045184 141 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
ribonucleotide catabolic process GO:0009261 136 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
dna metabolic process GO:0006259 96 0.010
circulatory system process GO:0003013 183 0.010
glycosyl compound metabolic process GO:1901657 182 0.010
enzyme linked receptor protein signaling pathway GO:0007167 116 0.010
embryonic axis specification GO:0000578 1 0.010
regulation of protein modification process GO:0031399 194 0.010

Egln1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
sensory system disease DOID:0050155 0 0.016
disease of cellular proliferation DOID:14566 0 0.010
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010