Rattus norvegicus

0 known processes

Apeh

N-acylaminoacyl-peptide hydrolase

Apeh biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.266
organic acid metabolic process GO:0006082 292 0.226
tetrapyrrole metabolic process GO:0033013 11 0.224
cofactor metabolic process GO:0051186 95 0.209
single organism biosynthetic process GO:0044711 342 0.161
carboxylic acid metabolic process GO:0019752 289 0.128
cellular component assembly GO:0022607 360 0.100
organic substance catabolic process GO:1901575 316 0.099
organonitrogen compound biosynthetic process GO:1901566 167 0.093
cellular component biogenesis GO:0044085 368 0.091
cellular lipid metabolic process GO:0044255 208 0.086
regulation of molecular function GO:0065009 398 0.081
lipid metabolic process GO:0006629 283 0.080
porphyrin containing compound metabolic process GO:0006778 8 0.077
porphyrin containing compound biosynthetic process GO:0006779 6 0.077
nucleobase containing small molecule metabolic process GO:0055086 316 0.074
single organism catabolic process GO:0044712 283 0.072
organic acid biosynthetic process GO:0016053 83 0.068
carbohydrate derivative metabolic process GO:1901135 346 0.065
regulation of catalytic activity GO:0050790 304 0.064
organophosphate metabolic process GO:0019637 370 0.063
response to extracellular stimulus GO:0009991 380 0.062
cofactor biosynthetic process GO:0051188 28 0.059
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.058
response to monosaccharide GO:0034284 159 0.057
coenzyme metabolic process GO:0006732 86 0.056
carbohydrate metabolic process GO:0005975 130 0.056
response to nutrient GO:0007584 248 0.056
response to carbohydrate GO:0009743 183 0.053
nucleoside phosphate metabolic process GO:0006753 283 0.051
oxidation reduction process GO:0055114 304 0.050
positive regulation of catalytic activity GO:0043085 184 0.050
monocarboxylic acid metabolic process GO:0032787 152 0.050
protein oligomerization GO:0051259 191 0.048
catabolic process GO:0009056 351 0.047
macromolecular complex assembly GO:0065003 273 0.046
response to nutrient levels GO:0031667 370 0.045
protein phosphorylation GO:0006468 345 0.045
response to transition metal nanoparticle GO:1990267 122 0.044
regulation of telomerase activity GO:0051972 2 0.044
protein complex assembly GO:0006461 263 0.043
regulation of rna biosynthetic process GO:2001141 381 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.041
positive regulation of cellular biosynthetic process GO:0031328 295 0.041
response to vitamin GO:0033273 131 0.040
macromolecular complex subunit organization GO:0043933 339 0.040
regulation of cellular protein metabolic process GO:0032268 267 0.038
response to toxic substance GO:0009636 133 0.038
response to hypoxia GO:0001666 231 0.038
positive regulation of molecular function GO:0044093 230 0.038
rna metabolic process GO:0016070 406 0.037
neuron differentiation GO:0030182 368 0.036
regulation of cellular component organization GO:0051128 368 0.036
response to glucose GO:0009749 136 0.036
protein complex biogenesis GO:0070271 263 0.035
single organism intracellular transport GO:1902582 166 0.035
response to external biotic stimulus GO:0043207 221 0.034
lipid biosynthetic process GO:0008610 128 0.034
tetrapyrrole biosynthetic process GO:0033014 7 0.034
nucleotide metabolic process GO:0009117 279 0.034
response to decreased oxygen levels GO:0036293 237 0.034
response to metal ion GO:0010038 253 0.034
cell projection organization GO:0030030 302 0.033
programmed cell death GO:0012501 392 0.033
regulation of transferase activity GO:0051338 123 0.033
cellular response to oxygen containing compound GO:1901701 386 0.032
cellular amino acid metabolic process GO:0006520 107 0.031
positive regulation of biosynthetic process GO:0009891 319 0.031
cell migration GO:0016477 197 0.031
localization of cell GO:0051674 202 0.030
heterocycle catabolic process GO:0046700 167 0.030
negative regulation of metabolic process GO:0009892 331 0.030
neuron projection development GO:0031175 273 0.030
cellular response to lipid GO:0071396 201 0.030
purine nucleotide metabolic process GO:0006163 229 0.030
central nervous system development GO:0007417 311 0.030
chemical homeostasis GO:0048878 292 0.030
brain development GO:0007420 247 0.029
response to oxygen levels GO:0070482 265 0.029
cellular response to stress GO:0033554 269 0.029
proteolysis GO:0006508 175 0.029
response to ethanol GO:0045471 162 0.028
response to peptide GO:1901652 292 0.028
purine ribonucleoside metabolic process GO:0046128 168 0.028
cellular amine metabolic process GO:0044106 38 0.028
intracellular transport GO:0046907 185 0.028
organelle organization GO:0006996 266 0.028
protein complex subunit organization GO:0071822 302 0.027
response to acid chemical GO:0001101 222 0.027
regulation of cellular localization GO:0060341 263 0.027
alpha amino acid biosynthetic process GO:1901607 23 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.026
cellular ketone metabolic process GO:0042180 51 0.026
neuron development GO:0048666 286 0.026
positive regulation of multicellular organismal process GO:0051240 387 0.025
glycosyl compound metabolic process GO:1901657 182 0.025
small molecule biosynthetic process GO:0044283 124 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.025
vesicle mediated transport GO:0016192 181 0.025
homeostatic process GO:0042592 331 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
macromolecule localization GO:0033036 252 0.024
cellular response to organic cyclic compound GO:0071407 202 0.024
response to amine GO:0014075 46 0.024
carboxylic acid biosynthetic process GO:0046394 83 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.024
response to biotic stimulus GO:0009607 226 0.024
single organism carbohydrate metabolic process GO:0044723 118 0.024
pigment biosynthetic process GO:0046148 4 0.023
positive regulation of transport GO:0051050 245 0.023
response to inorganic substance GO:0010035 377 0.023
purine nucleoside metabolic process GO:0042278 169 0.023
single organism cellular localization GO:1902580 102 0.023
response to corticosteroid GO:0031960 235 0.023
alpha amino acid metabolic process GO:1901605 71 0.023
response to hexose GO:0009746 144 0.023
amine metabolic process GO:0009308 38 0.023
response to other organism GO:0051707 220 0.022
cellular catabolic process GO:0044248 295 0.022
synaptic transmission GO:0007268 235 0.022
cellular response to endogenous stimulus GO:0071495 377 0.022
ribonucleoside metabolic process GO:0009119 174 0.022
regulation of nervous system development GO:0051960 264 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
cellular response to hormone stimulus GO:0032870 247 0.021
nucleic acid templated transcription GO:0097659 379 0.021
regulation of programmed cell death GO:0043067 341 0.021
intracellular protein transport GO:0006886 79 0.021
negative regulation of cellular component organization GO:0051129 83 0.021
cell motility GO:0048870 202 0.020
aging GO:0007568 241 0.020
negative regulation of transport GO:0051051 136 0.020
regulation of protein modification process GO:0031399 194 0.020
regulation of cell projection organization GO:0031344 175 0.020
carboxylic acid catabolic process GO:0046395 49 0.020
organic anion transport GO:0015711 132 0.020
transmembrane transport GO:0055085 412 0.020
purine containing compound metabolic process GO:0072521 253 0.020
negative regulation of cellular protein metabolic process GO:0032269 106 0.019
negative regulation of molecular function GO:0044092 133 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.019
hexose metabolic process GO:0019318 58 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
cellular nitrogen compound catabolic process GO:0044270 163 0.019
cytoplasmic transport GO:0016482 115 0.019
protein targeting GO:0006605 61 0.019
nucleoside triphosphate metabolic process GO:0009141 144 0.019
nicotinamide nucleotide metabolic process GO:0046496 28 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
secretion GO:0046903 307 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
cellular component movement GO:0006928 248 0.018
regulation of protein metabolic process GO:0051246 289 0.018
anion transport GO:0006820 178 0.018
purine ribonucleoside catabolic process GO:0046130 124 0.018
rna biosynthetic process GO:0032774 380 0.018
nucleoside metabolic process GO:0009116 179 0.018
carbohydrate derivative biosynthetic process GO:1901137 124 0.018
cellular macromolecule localization GO:0070727 122 0.018
cellular amino acid biosynthetic process GO:0008652 32 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
nitrogen compound transport GO:0071705 229 0.017
regulation of phosphorylation GO:0042325 248 0.017
blood circulation GO:0008015 183 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
regulation of cell proliferation GO:0042127 359 0.017
immune system process GO:0002376 204 0.017
heme biosynthetic process GO:0006783 4 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
regulation of phosphate metabolic process GO:0019220 349 0.017
regulation of nucleic acid templated transcription GO:1903506 380 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
dna metabolic process GO:0006259 96 0.017
organophosphate catabolic process GO:0046434 148 0.017
purine ribonucleotide catabolic process GO:0009154 136 0.016
head development GO:0060322 247 0.016
response to radiation GO:0009314 137 0.016
carboxylic acid transport GO:0046942 115 0.016
regulation of apoptotic process GO:0042981 335 0.016
protein maturation GO:0051604 68 0.016
cellular component morphogenesis GO:0032989 155 0.016
regulation of membrane potential GO:0042391 110 0.016
nucleoside catabolic process GO:0009164 126 0.016
positive regulation of response to stimulus GO:0048584 285 0.016
regulation of anatomical structure size GO:0090066 135 0.016
response to bacterium GO:0009617 200 0.016
ribonucleoside catabolic process GO:0042454 126 0.016
ribonucleoside triphosphate catabolic process GO:0009203 122 0.016
apoptotic process GO:0006915 381 0.016
purine nucleoside catabolic process GO:0006152 124 0.016
regulation of neuron projection development GO:0010975 161 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
organophosphate biosynthetic process GO:0090407 143 0.016
purine nucleotide catabolic process GO:0006195 136 0.015
regulation of transcription dna templated GO:0006355 374 0.015
response to amino acid GO:0043200 75 0.015
response to peptide hormone GO:0043434 278 0.015
regulation of neuron differentiation GO:0045664 208 0.015
purine nucleoside triphosphate catabolic process GO:0009146 122 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
small molecule catabolic process GO:0044282 59 0.015
cation transport GO:0006812 382 0.015
ion transmembrane transport GO:0034220 365 0.015
regulation of system process GO:0044057 208 0.015
cellular response to external stimulus GO:0071496 118 0.015
reproductive system development GO:0061458 128 0.015
protein homooligomerization GO:0051260 91 0.015
positive regulation of signaling GO:0023056 270 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
regulation of signal transduction GO:0009966 318 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
regulation of cell differentiation GO:0045595 320 0.014
organic acid catabolic process GO:0016054 49 0.014
metal ion transport GO:0030001 289 0.014
cation transmembrane transport GO:0098655 263 0.014
synaptic growth at neuromuscular junction GO:0051124 1 0.014
cell projection morphogenesis GO:0048858 123 0.014
regulation of rna metabolic process GO:0051252 391 0.014
positive regulation of cell development GO:0010720 176 0.014
purine containing compound catabolic process GO:0072523 138 0.014
cell cell signaling GO:0007267 335 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
regulation of cell development GO:0060284 263 0.014
glycerolipid metabolic process GO:0046486 67 0.014
protein modification by small protein conjugation or removal GO:0070647 35 0.014
response to cytokine GO:0034097 215 0.014
regulation of hydrolase activity GO:0051336 143 0.014
ncrna processing GO:0034470 3 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
ribonucleotide catabolic process GO:0009261 136 0.014
response to estradiol GO:0032355 164 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.014
regulation of nucleotide metabolic process GO:0006140 117 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
single organism reproductive process GO:0044702 297 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
cellular modified amino acid biosynthetic process GO:0042398 18 0.013
fatty acid metabolic process GO:0006631 99 0.013
regulation of neurogenesis GO:0050767 247 0.013
response to estrogen GO:0043627 232 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
metal ion homeostasis GO:0055065 186 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
positive regulation of gene expression GO:0010628 244 0.013
gastrulation GO:0007369 2 0.013
monosaccharide metabolic process GO:0005996 61 0.013
growth GO:0040007 165 0.013
nucleotide catabolic process GO:0009166 139 0.013
amide transport GO:0042886 105 0.013
regeneration GO:0031099 163 0.013
negative regulation of cellular metabolic process GO:0031324 281 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
liver development GO:0001889 90 0.013
single organism membrane organization GO:0044802 74 0.013
response to zinc ion GO:0010043 39 0.013
protein modification by small protein conjugation GO:0032446 31 0.013
regulation of kinase activity GO:0043549 117 0.013
peptide transport GO:0015833 97 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
signal release GO:0023061 145 0.012
regulation of intracellular transport GO:0032386 65 0.012
response to ketone GO:1901654 182 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
neurological system process GO:0050877 219 0.012
response to glucocorticoid GO:0051384 223 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
membrane organization GO:0061024 94 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
ion homeostasis GO:0050801 212 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
regulation of catabolic process GO:0009894 113 0.012
circulatory system process GO:0003013 183 0.012
protein transport GO:0015031 132 0.012
anion transmembrane transport GO:0098656 77 0.012
cellular homeostasis GO:0019725 252 0.012
response to fungicide GO:0060992 20 0.012
pigment metabolic process GO:0042440 7 0.012
regulation of vesicle mediated transport GO:0060627 81 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
positive regulation of developmental process GO:0051094 283 0.012
rhythmic process GO:0048511 156 0.012
cell part morphogenesis GO:0032990 123 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
response to herbicide GO:0009635 16 0.012
response to wounding GO:0009611 254 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
cellular modified amino acid metabolic process GO:0006575 61 0.012
protein processing GO:0016485 68 0.011
adult locomotory behavior GO:0008344 4 0.011
positive regulation of transferase activity GO:0051347 81 0.011
protein heterooligomerization GO:0051291 89 0.011
macroautophagy GO:0016236 4 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
regulation of hormone levels GO:0010817 187 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
developmental growth GO:0048589 100 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
cation homeostasis GO:0055080 195 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
locomotion GO:0040011 237 0.011
gland development GO:0048732 155 0.011
reproduction GO:0000003 245 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
regulation of homeostatic process GO:0032844 101 0.011
negative regulation of cell communication GO:0010648 158 0.011
cell adhesion GO:0007155 110 0.011
dephosphorylation GO:0016311 98 0.011
hepaticobiliary system development GO:0061008 90 0.011
response to temperature stimulus GO:0009266 94 0.011
negative regulation of signaling GO:0023057 157 0.011
hormone transport GO:0009914 121 0.011
chromosome segregation GO:0007059 2 0.011
regulation of response to stress GO:0080134 126 0.011
single organism organelle organization GO:1902589 180 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
organic acid transport GO:0015849 116 0.011
aromatic compound catabolic process GO:0019439 168 0.011
cellular response to topologically incorrect protein GO:0035967 3 0.011
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
pyridine containing compound metabolic process GO:0072524 32 0.010
intracellular signal transduction GO:0035556 314 0.010
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.010
peptidyl amino acid modification GO:0018193 126 0.010
transmission of nerve impulse GO:0019226 42 0.010
positive regulation of nucleic acid templated transcription GO:1903508 197 0.010
reproductive process GO:0022414 372 0.010
response to fatty acid GO:0070542 65 0.010
protein localization GO:0008104 191 0.010
axis specification GO:0009798 4 0.010
regulation of locomotion GO:0040012 148 0.010
single organism behavior GO:0044708 130 0.010
regulation of cellular catabolic process GO:0031329 101 0.010

Apeh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.101
disease of anatomical entity DOID:7 0 0.101
musculoskeletal system disease DOID:17 0 0.101
myopathy DOID:423 0 0.082
muscle tissue disease DOID:66 0 0.082
muscular dystrophy DOID:9884 0 0.042
disease of metabolism DOID:0014667 0 0.030
inherited metabolic disorder DOID:655 0 0.030
nervous system disease DOID:863 0 0.012