Rattus norvegicus

0 known processes

Cops8

COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)

Cops8 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular protein metabolic process GO:0032268 267 0.124
regulation of protein metabolic process GO:0051246 289 0.106
positive regulation of phosphorus metabolic process GO:0010562 262 0.093
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.091
response to peptide GO:1901652 292 0.087
negative regulation of translation in response to stress GO:0032055 5 0.078
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.077
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.075
regulation of phosphate metabolic process GO:0019220 349 0.068
regulation of transcription dna templated GO:0006355 374 0.066
macromolecule localization GO:0033036 252 0.064
transcription dna templated GO:0006351 377 0.064
regulation of phosphorus metabolic process GO:0051174 349 0.063
positive regulation of phosphate metabolic process GO:0045937 262 0.062
transcription from rna polymerase ii promoter GO:0006366 252 0.057
nucleic acid templated transcription GO:0097659 379 0.056
positive regulation of cell death GO:0010942 184 0.055
catabolic process GO:0009056 351 0.054
negative regulation of metabolic process GO:0009892 331 0.054
regulation of rna biosynthetic process GO:2001141 381 0.054
regulation of signal transduction GO:0009966 318 0.053
regulation of nucleic acid templated transcription GO:1903506 380 0.052
ribonucleoside triphosphate catabolic process GO:0009203 122 0.050
response to peptide hormone GO:0043434 278 0.049
atp catabolic process GO:0006200 54 0.049
regulation of molecular function GO:0065009 398 0.049
regulation of catalytic activity GO:0050790 304 0.048
organic substance catabolic process GO:1901575 316 0.046
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.046
carbohydrate derivative catabolic process GO:1901136 147 0.043
regulation of apoptotic process GO:0042981 335 0.042
apoptotic process GO:0006915 381 0.042
ribonucleoside metabolic process GO:0009119 174 0.040
response to carbohydrate GO:0009743 183 0.040
nucleoside monophosphate catabolic process GO:0009125 56 0.038
organonitrogen compound catabolic process GO:1901565 179 0.037
positive regulation of nucleic acid templated transcription GO:1903508 197 0.037
purine nucleotide catabolic process GO:0006195 136 0.037
protein transport GO:0015031 132 0.037
response to monosaccharide GO:0034284 159 0.037
cation transmembrane transport GO:0098655 263 0.036
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.036
positive regulation of signaling GO:0023056 270 0.035
regulation of protein modification process GO:0031399 194 0.035
regulation of multicellular organismal development GO:2000026 376 0.035
cellular catabolic process GO:0044248 295 0.034
organophosphate metabolic process GO:0019637 370 0.034
positive regulation of cellular biosynthetic process GO:0031328 295 0.034
ribose phosphate metabolic process GO:0019693 235 0.034
nucleoside catabolic process GO:0009164 126 0.034
protein localization GO:0008104 191 0.033
negative regulation of protein metabolic process GO:0051248 114 0.033
regulation of cell proliferation GO:0042127 359 0.033
cellular response to stress GO:0033554 269 0.033
positive regulation of gene expression GO:0010628 244 0.033
intracellular transport GO:0046907 185 0.032
positive regulation of rna biosynthetic process GO:1902680 197 0.032
purine ribonucleotide metabolic process GO:0009150 227 0.032
intracellular signal transduction GO:0035556 314 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.031
negative regulation of response to stimulus GO:0048585 155 0.031
glycosyl compound catabolic process GO:1901658 126 0.031
protein phosphorylation GO:0006468 345 0.031
glycosyl compound metabolic process GO:1901657 182 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.030
response to hexose GO:0009746 144 0.030
positive regulation of molecular function GO:0044093 230 0.030
regulation of cellular component organization GO:0051128 368 0.030
purine ribonucleoside catabolic process GO:0046130 124 0.029
negative regulation of biosynthetic process GO:0009890 168 0.029
ribonucleoside catabolic process GO:0042454 126 0.029
regulation of intracellular signal transduction GO:1902531 218 0.029
regulation of translation in response to stress GO:0043555 5 0.029
small gtpase mediated signal transduction GO:0007264 36 0.028
purine containing compound metabolic process GO:0072521 253 0.028
regulation of hydrolase activity GO:0051336 143 0.028
negative regulation of cellular metabolic process GO:0031324 281 0.027
purine ribonucleotide catabolic process GO:0009154 136 0.027
response to glucose GO:0009749 136 0.027
guanosine containing compound catabolic process GO:1901069 71 0.027
rna metabolic process GO:0016070 406 0.026
positive regulation of cell communication GO:0010647 271 0.026
positive regulation of transcription dna templated GO:0045893 197 0.025
organophosphate catabolic process GO:0046434 148 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
purine nucleoside metabolic process GO:0042278 169 0.025
purine nucleotide metabolic process GO:0006163 229 0.025
negative regulation of cellular protein metabolic process GO:0032269 106 0.024
secretion by cell GO:0032940 248 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
positive regulation of rna metabolic process GO:0051254 203 0.024
ion transmembrane transport GO:0034220 365 0.024
positive regulation of cell proliferation GO:0008284 249 0.024
gastrulation GO:0007369 2 0.024
regulation of catabolic process GO:0009894 113 0.023
regulation of programmed cell death GO:0043067 341 0.023
purine ribonucleoside metabolic process GO:0046128 168 0.023
response to cytokine GO:0034097 215 0.023
regulation of cell development GO:0060284 263 0.023
nucleoside triphosphate catabolic process GO:0009143 123 0.023
cellular amine metabolic process GO:0044106 38 0.023
positive regulation of biosynthetic process GO:0009891 319 0.023
cellular chemical homeostasis GO:0055082 247 0.023
negative regulation of gene expression GO:0010629 199 0.023
ribonucleoside triphosphate metabolic process GO:0009199 141 0.023
cellular homeostasis GO:0019725 252 0.022
organic cyclic compound catabolic process GO:1901361 175 0.022
regulation of rna metabolic process GO:0051252 391 0.022
regulation of cell differentiation GO:0045595 320 0.022
cellular nitrogen compound catabolic process GO:0044270 163 0.022
amine metabolic process GO:0009308 38 0.022
cellular response to lipid GO:0071396 201 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.022
nucleotide catabolic process GO:0009166 139 0.022
mesoderm development GO:0007498 2 0.022
aromatic compound catabolic process GO:0019439 168 0.021
nucleoside triphosphate metabolic process GO:0009141 144 0.021
central nervous system development GO:0007417 311 0.021
negative regulation of multicellular organismal process GO:0051241 203 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
heterocycle catabolic process GO:0046700 167 0.021
regulation of nervous system development GO:0051960 264 0.021
negative regulation of cell death GO:0060548 229 0.020
inorganic ion transmembrane transport GO:0098660 229 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
protein complex biogenesis GO:0070271 263 0.020
rna biosynthetic process GO:0032774 380 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.020
ras protein signal transduction GO:0007265 29 0.020
translation GO:0006412 35 0.020
positive regulation of developmental process GO:0051094 283 0.020
purine nucleoside triphosphate catabolic process GO:0009146 122 0.020
positive regulation of hydrolase activity GO:0051345 86 0.020
response to ethanol GO:0045471 162 0.019
transmembrane transport GO:0055085 412 0.019
oxoacid metabolic process GO:0043436 290 0.019
macromolecular complex subunit organization GO:0043933 339 0.019
anatomical structure morphogenesis GO:0009653 298 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
cation transport GO:0006812 382 0.019
ribonucleotide catabolic process GO:0009261 136 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
nucleoside monophosphate metabolic process GO:0009123 93 0.018
organelle organization GO:0006996 266 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
homeostatic process GO:0042592 331 0.018
reproductive process GO:0022414 372 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
negative regulation of signaling GO:0023057 157 0.018
purine nucleoside triphosphate metabolic process GO:0009144 141 0.018
purine nucleoside monophosphate catabolic process GO:0009128 55 0.018
establishment of protein localization GO:0045184 141 0.018
negative regulation of cell communication GO:0010648 158 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
negative regulation of translational initiation GO:0045947 5 0.017
positive regulation of nucleotide metabolic process GO:0045981 91 0.017
regulation of phosphorylation GO:0042325 248 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
positive regulation of response to stimulus GO:0048584 285 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
programmed cell death GO:0012501 392 0.017
nucleoside metabolic process GO:0009116 179 0.017
cellular macromolecule localization GO:0070727 122 0.017
negative regulation of developmental process GO:0051093 125 0.017
positive regulation of protein modification process GO:0031401 142 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.016
ribonucleoside monophosphate catabolic process GO:0009158 55 0.016
head development GO:0060322 247 0.016
negative regulation of cell development GO:0010721 82 0.016
negative regulation of cell differentiation GO:0045596 99 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.015
chemical homeostasis GO:0048878 292 0.015
response to oxidative stress GO:0006979 186 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.015
guanosine containing compound metabolic process GO:1901068 74 0.015
multicellular organism reproduction GO:0032504 233 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
cellular response to growth factor stimulus GO:0071363 162 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
histone methylation GO:0016571 3 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
neuron death GO:0070997 127 0.014
protein prenylation GO:0018342 4 0.014
cellular amino acid metabolic process GO:0006520 107 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
positive regulation of signal transduction GO:0009967 175 0.014
regulation of translation GO:0006417 27 0.014
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.014
cellular component assembly GO:0022607 360 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
formation of primary germ layer GO:0001704 1 0.013
single organism catabolic process GO:0044712 283 0.013
positive regulation of catabolic process GO:0009896 78 0.013
single organism organelle organization GO:1902589 180 0.013
cellular component biogenesis GO:0044085 368 0.013
nucleotide metabolic process GO:0009117 279 0.013
ribonucleoside monophosphate metabolic process GO:0009161 88 0.013
growth GO:0040007 165 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
neuron differentiation GO:0030182 368 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.012
purine nucleoside monophosphate metabolic process GO:0009126 84 0.012
localization of cell GO:0051674 202 0.012
regulation of mapk cascade GO:0043408 116 0.012
brain development GO:0007420 247 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
response to acid chemical GO:0001101 222 0.012
cellular ketone metabolic process GO:0042180 51 0.012
cardiac chamber development GO:0003205 1 0.012
purine nucleotide biosynthetic process GO:0006164 83 0.012
cellular component morphogenesis GO:0032989 155 0.012
response to growth factor GO:0070848 189 0.012
positive regulation of neuron death GO:1901216 43 0.012
atp metabolic process GO:0046034 72 0.011
response to ketone GO:1901654 182 0.011
response to oxygen levels GO:0070482 265 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
action potential GO:0001508 54 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
tissue development GO:0009888 252 0.011
mapk cascade GO:0000165 140 0.011
cell migration GO:0016477 197 0.011
macromolecular complex assembly GO:0065003 273 0.011
metal ion transport GO:0030001 289 0.011
regulation of neuron death GO:1901214 115 0.011
gamete generation GO:0007276 124 0.011
regulation of cell migration GO:0030334 128 0.011
muscle system process GO:0003012 115 0.011
positive regulation of nucleotide catabolic process GO:0030813 53 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
negative regulation of transport GO:0051051 136 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
protein complex assembly GO:0006461 263 0.011
anterior posterior pattern specification GO:0009952 1 0.011
response to decreased oxygen levels GO:0036293 237 0.010
regulation of neurogenesis GO:0050767 247 0.010
positive regulation of nervous system development GO:0051962 178 0.010
purine containing compound biosynthetic process GO:0072522 85 0.010
cellular component movement GO:0006928 248 0.010
regulation of transferase activity GO:0051338 123 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
negative regulation of signal transduction GO:0009968 83 0.010
positive regulation of mapk cascade GO:0043410 92 0.010
embryonic pattern specification GO:0009880 1 0.010
rna localization GO:0006403 4 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
multi organism reproductive process GO:0044703 262 0.010

Cops8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017