Rattus norvegicus

209 known processes

Rps6kb1

ribosomal protein S6 kinase, polypeptide 1

Rps6kb1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macromolecular complex subunit organization GO:0043933 339 0.259
Fly
ribonucleoside metabolic process GO:0009119 174 0.221
protein complex assembly GO:0006461 263 0.217
single organism biosynthetic process GO:0044711 342 0.184
negative regulation of cellular metabolic process GO:0031324 281 0.153
positive regulation of membrane potential GO:0045838 16 0.150
nucleoside triphosphate metabolic process GO:0009141 144 0.126
organophosphate metabolic process GO:0019637 370 0.091
regulation of signal transduction GO:0009966 318 0.087
protein complex subunit organization GO:0071822 302 0.084
Fly
regulation of phosphorus metabolic process GO:0051174 349 0.082
regulation of phosphate metabolic process GO:0019220 349 0.081
regulation of protein metabolic process GO:0051246 289 0.080
Human
reproduction GO:0000003 245 0.079
Mouse Worm Fly
ribose phosphate metabolic process GO:0019693 235 0.077
cellular catabolic process GO:0044248 295 0.074
Worm Fly
tissue development GO:0009888 252 0.068
cell part morphogenesis GO:0032990 123 0.067
Fly
cellular component biogenesis GO:0044085 368 0.066
Worm Fly
purine ribonucleotide catabolic process GO:0009154 136 0.065
regulation of catalytic activity GO:0050790 304 0.065
macromolecular complex assembly GO:0065003 273 0.065
purine containing compound metabolic process GO:0072521 253 0.065
nucleic acid templated transcription GO:0097659 379 0.064
protein complex biogenesis GO:0070271 263 0.062
nucleotide metabolic process GO:0009117 279 0.062
regulation of molecular function GO:0065009 398 0.061
positive regulation of response to stimulus GO:0048584 285 0.061
Worm Fly
transcription dna templated GO:0006351 377 0.060
glycosyl compound metabolic process GO:1901657 182 0.060
regulation of rna biosynthetic process GO:2001141 381 0.059
rna biosynthetic process GO:0032774 380 0.055
cell cycle GO:0007049 101 0.054
Human
oxoacid metabolic process GO:0043436 290 0.053
carbohydrate derivative metabolic process GO:1901135 346 0.053
response to nutrient levels GO:0031667 370 0.053
negative regulation of protein metabolic process GO:0051248 114 0.052
rna metabolic process GO:0016070 406 0.052
nucleoside metabolic process GO:0009116 179 0.051
positive regulation of cellular component organization GO:0051130 200 0.050
Worm
purine nucleoside metabolic process GO:0042278 169 0.050
cellular response to endogenous stimulus GO:0071495 377 0.050
organ regeneration GO:0031100 101 0.049
organonitrogen compound catabolic process GO:1901565 179 0.048
response to decreased oxygen levels GO:0036293 237 0.047
protein oligomerization GO:0051259 191 0.046
aromatic compound catabolic process GO:0019439 168 0.045
purine nucleotide metabolic process GO:0006163 229 0.045
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.045
cell cycle process GO:0022402 57 0.045
Human
negative regulation of macromolecule metabolic process GO:0010605 260 0.044
necroptotic process GO:0070266 2 0.044
catabolic process GO:0009056 351 0.044
Worm Fly
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.043
alpha amino acid metabolic process GO:1901605 71 0.043
mesoderm development GO:0007498 2 0.043
purine ribonucleoside metabolic process GO:0046128 168 0.043
carboxylic acid metabolic process GO:0019752 289 0.042
anatomical structure morphogenesis GO:0009653 298 0.041
Fly
regulation of hydrolase activity GO:0051336 143 0.041
nucleoside phosphate metabolic process GO:0006753 283 0.040
cellular response to stress GO:0033554 269 0.039
Worm Fly
alternative mrna splicing via spliceosome GO:0000380 4 0.039
ribonucleotide metabolic process GO:0009259 231 0.039
positive regulation of molecular function GO:0044093 230 0.038
carbohydrate derivative catabolic process GO:1901136 147 0.038
regulation of nervous system development GO:0051960 264 0.037
positive regulation of rna biosynthetic process GO:1902680 197 0.037
cellular amino acid metabolic process GO:0006520 107 0.037
regulation of rna metabolic process GO:0051252 391 0.036
protein homooligomerization GO:0051260 91 0.036
nucleotide biosynthetic process GO:0009165 98 0.036
organic acid metabolic process GO:0006082 292 0.035
positive regulation of biosynthetic process GO:0009891 319 0.035
Human
negative regulation of gene expression GO:0010629 199 0.035
response to cytokine GO:0034097 215 0.035
chromosome segregation GO:0007059 2 0.035
ribonucleoside catabolic process GO:0042454 126 0.034
regulation of cellular protein metabolic process GO:0032268 267 0.034
Human
nucleoside triphosphate catabolic process GO:0009143 123 0.034
positive regulation of developmental process GO:0051094 283 0.034
response to oxygen levels GO:0070482 265 0.033
cellular macromolecular complex assembly GO:0034622 58 0.033
regulation of cellular catabolic process GO:0031329 101 0.033
Worm Fly
positive regulation of nucleic acid templated transcription GO:1903508 197 0.033
glutamine family amino acid metabolic process GO:0009064 15 0.032
nucleobase containing small molecule metabolic process GO:0055086 316 0.032
coenzyme metabolic process GO:0006732 86 0.032
regulation of catabolic process GO:0009894 113 0.031
Worm Fly
cofactor metabolic process GO:0051186 95 0.031
organic cyclic compound catabolic process GO:1901361 175 0.031
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.031
proteolysis GO:0006508 175 0.031
cellular nitrogen compound catabolic process GO:0044270 163 0.031
cellular ketone metabolic process GO:0042180 51 0.031
regulation of protein modification process GO:0031399 194 0.031
purine ribonucleoside catabolic process GO:0046130 124 0.030
neuron development GO:0048666 286 0.030
Fly
regulation of phosphorylation GO:0042325 248 0.030
aging GO:0007568 241 0.030
positive regulation of mitochondrion organization GO:0010822 4 0.030
negative regulation of metabolic process GO:0009892 331 0.029
purine nucleoside triphosphate catabolic process GO:0009146 122 0.029
neuron projection development GO:0031175 273 0.029
Fly
response to transition metal nanoparticle GO:1990267 122 0.028
regulation of cellular response to stress GO:0080135 49 0.028
Worm Fly
purine containing compound biosynthetic process GO:0072522 85 0.028
positive regulation of transcription dna templated GO:0045893 197 0.028
growth GO:0040007 165 0.028
amine metabolic process GO:0009308 38 0.028
protein phosphorylation GO:0006468 345 0.028
small gtpase mediated signal transduction GO:0007264 36 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.027
purine nucleotide catabolic process GO:0006195 136 0.027
response to inorganic substance GO:0010035 377 0.027
regulation of transforming growth factor beta3 production GO:0032910 2 0.026
regulation of cellular localization GO:0060341 263 0.026
heterocycle catabolic process GO:0046700 167 0.026
mitotic cell cycle GO:0000278 49 0.025
Human
kidney development GO:0001822 67 0.025
regulation of protein phosphorylation GO:0001932 183 0.025
ribonucleoside triphosphate metabolic process GO:0009199 141 0.025
regulation of response to stress GO:0080134 126 0.025
Worm Fly
intracellular signal transduction GO:0035556 314 0.025
Human Mouse
protein prenylation GO:0018342 4 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
multicellular organism growth GO:0035264 1 0.024
Fly
purine containing compound catabolic process GO:0072523 138 0.024
cellular component assembly GO:0022607 360 0.024
Worm Fly
positive regulation of catalytic activity GO:0043085 184 0.024
dna metabolic process GO:0006259 96 0.024
positive regulation of protein metabolic process GO:0051247 178 0.024
Human
regulation of cell differentiation GO:0045595 320 0.024
positive regulation of transport GO:0051050 245 0.024
positive regulation of rna metabolic process GO:0051254 203 0.024
single organism reproductive process GO:0044702 297 0.024
Mouse Fly
positive regulation of intracellular signal transduction GO:1902533 138 0.024
regulation of organelle organization GO:0033043 80 0.024
Worm
lipid metabolic process GO:0006629 283 0.024
Fly
regulation of cell proliferation GO:0042127 359 0.024
regulation of mrna splicing via spliceosome GO:0048024 3 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.023
positive regulation of cell differentiation GO:0045597 217 0.023
negative regulation of cell cycle phase transition GO:1901988 4 0.023
vesicle mediated transport GO:0016192 181 0.023
Fly
regulation of cellular amine metabolic process GO:0033238 8 0.023
developmental process involved in reproduction GO:0003006 159 0.023
Mouse Fly
cellular protein localization GO:0034613 122 0.022
response to temperature stimulus GO:0009266 94 0.022
signal transduction by phosphorylation GO:0023014 144 0.022
sexual reproduction GO:0019953 148 0.022
Mouse Fly
negative regulation of cellular protein metabolic process GO:0032269 106 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.021
positive regulation of secretion by cell GO:1903532 128 0.021
axis specification GO:0009798 4 0.021
renal system development GO:0072001 67 0.021
response to estrogen GO:0043627 232 0.021
enzyme linked receptor protein signaling pathway GO:0007167 116 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
neurological system process GO:0050877 219 0.021
organonitrogen compound biosynthetic process GO:1901566 167 0.021
posttranscriptional regulation of gene expression GO:0010608 37 0.020
Human
regulation of multicellular organismal development GO:2000026 376 0.020
response to radiation GO:0009314 137 0.020
response to extracellular stimulus GO:0009991 380 0.020
purine ribonucleotide biosynthetic process GO:0009152 81 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
Human
asymmetric protein localization GO:0008105 2 0.020
nucleoside phosphate catabolic process GO:1901292 140 0.019
purine nucleotide biosynthetic process GO:0006164 83 0.019
single organism organelle organization GO:1902589 180 0.019
Fly
response to hypoxia GO:0001666 231 0.019
endoplasmic reticulum organization GO:0007029 1 0.019
hexose metabolic process GO:0019318 58 0.018
macromolecule localization GO:0033036 252 0.018
regulation of cell cycle g2 m phase transition GO:1902749 4 0.018
carbohydrate derivative biosynthetic process GO:1901137 124 0.018
response to metal ion GO:0010038 253 0.018
programmed necrotic cell death GO:0097300 2 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
peristalsis GO:0030432 2 0.018
regulation of cell cycle GO:0051726 73 0.018
Human
ribonucleotide catabolic process GO:0009261 136 0.018
nucleotide catabolic process GO:0009166 139 0.018
regulation of mapk cascade GO:0043408 116 0.018
gtp catabolic process GO:0006184 71 0.018
nucleoside phosphate biosynthetic process GO:1901293 102 0.018
response to alkaloid GO:0043279 132 0.017
positive regulation of signaling GO:0023056 270 0.017
positive regulation of apoptotic process GO:0043065 154 0.017
organophosphate catabolic process GO:0046434 148 0.017
response to growth factor GO:0070848 189 0.017
Human
protein localization GO:0008104 191 0.017
cellular amine metabolic process GO:0044106 38 0.017
single organism intracellular transport GO:1902582 166 0.017
homeostatic process GO:0042592 331 0.017
positive regulation of signal transduction GO:0009967 175 0.017
secretion GO:0046903 307 0.017
negative regulation of catalytic activity GO:0043086 103 0.017
cellular response to nitrogen compound GO:1901699 210 0.016
regulation of protein localization GO:0032880 81 0.016
circulatory system development GO:0072359 134 0.016
rhythmic process GO:0048511 156 0.016
endocytosis GO:0006897 84 0.016
Fly
positive regulation of neuron differentiation GO:0045666 126 0.016
defense response GO:0006952 194 0.016
endomembrane system organization GO:0010256 48 0.016
positive regulation of mapk cascade GO:0043410 92 0.016
brain development GO:0007420 247 0.016
protein transport GO:0015031 132 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
multi organism reproductive process GO:0044703 262 0.016
Mouse Fly
regulation of g2 m transition of mitotic cell cycle GO:0010389 4 0.016
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.015
regulation of protein transport GO:0051223 68 0.015
multicellular organism reproduction GO:0032504 233 0.015
Mouse Fly
cell projection organization GO:0030030 302 0.015
Fly
organic substance catabolic process GO:1901575 316 0.015
regulation of membrane potential GO:0042391 110 0.015
cellular component morphogenesis GO:0032989 155 0.015
Fly
reproductive process GO:0022414 372 0.015
Mouse Fly
muscle structure development GO:0061061 87 0.015
protein processing GO:0016485 68 0.015
glycosyl compound catabolic process GO:1901658 126 0.015
regulation of developmental growth GO:0048638 45 0.015
regulation of secretion GO:0051046 224 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
Human
regulation of cellular ketone metabolic process GO:0010565 27 0.015
regulation of secretion by cell GO:1903530 208 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
programmed cell death GO:0012501 392 0.015
Human Mouse
positive regulation of release of cytochrome c from mitochondria GO:0090200 3 0.015
maintenance of location GO:0051235 17 0.014
cytokine production GO:0001816 61 0.014
mitotic cell cycle process GO:1903047 35 0.014
Human
secretion by cell GO:0032940 248 0.014
regulation of neuron projection development GO:0010975 161 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
Fly
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
regulation of establishment of protein localization GO:0070201 69 0.014
regulation of cellular component organization GO:0051128 368 0.014
Worm
embryonic axis specification GO:0000578 1 0.013
regulation of neurogenesis GO:0050767 247 0.013
nucleoside catabolic process GO:0009164 126 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
single organism membrane organization GO:0044802 74 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
localization of cell GO:0051674 202 0.013
cell cycle checkpoint GO:0000075 2 0.013
response to purine containing compound GO:0014074 126 0.013
locomotion GO:0040011 237 0.013
metanephric tubule morphogenesis GO:0072173 2 0.013
nucleocytoplasmic transport GO:0006913 48 0.013
biological adhesion GO:0022610 110 0.013
regulation of transcription dna templated GO:0006355 374 0.013
ion homeostasis GO:0050801 212 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
cellular protein complex assembly GO:0043623 44 0.012
gtp metabolic process GO:0046039 72 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
urogenital system development GO:0001655 78 0.012
cellular response to peptide GO:1901653 133 0.012
developmental growth GO:0048589 100 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
regulation of growth GO:0040008 105 0.012
regulation of nucleic acid templated transcription GO:1903506 380 0.012
positive regulation of cell communication GO:0010647 271 0.012
Worm Fly
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
Fly
positive regulation of multicellular organismal process GO:0051240 387 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
guanosine containing compound catabolic process GO:1901069 71 0.012
response to ammonium ion GO:0060359 71 0.012
positive regulation of cell development GO:0010720 176 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
Mouse Fly
cellular macromolecule catabolic process GO:0044265 29 0.012
activation of phospholipase d activity GO:0031584 2 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
regulation of vesicle mediated transport GO:0060627 81 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
Human
positive regulation of gene expression GO:0010628 244 0.012
Human
cellular response to organonitrogen compound GO:0071417 197 0.012
purine ribonucleoside biosynthetic process GO:0046129 21 0.012
coenzyme biosynthetic process GO:0009108 22 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.012
regulation of cell development GO:0060284 263 0.012
cell migration GO:0016477 197 0.011
positive regulation of cell death GO:0010942 184 0.011
negative regulation of endopeptidase activity GO:0010951 36 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
anterior posterior pattern specification GO:0009952 1 0.011
reproductive structure development GO:0048608 128 0.011
potassium ion transport GO:0006813 97 0.011
regulation of neuron differentiation GO:0045664 208 0.011
regulation of protein secretion GO:0050708 28 0.011
cellular chemical homeostasis GO:0055082 247 0.011
organelle organization GO:0006996 266 0.011
Worm Fly
organophosphate biosynthetic process GO:0090407 143 0.011
lipid storage GO:0019915 1 0.011
apoptotic process GO:0006915 381 0.011
Human Mouse
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.011
Mouse Fly
protein modification by small protein conjugation or removal GO:0070647 35 0.011
protein secretion GO:0009306 34 0.011
response to gamma radiation GO:0010332 24 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
Worm Fly
negative regulation of rna metabolic process GO:0051253 123 0.011
response to organophosphorus GO:0046683 102 0.010
neuron projection morphogenesis GO:0048812 122 0.010
Fly
positive regulation of nervous system development GO:0051962 178 0.010
response to reactive oxygen species GO:0000302 120 0.010
head development GO:0060322 247 0.010
epithelium development GO:0060429 96 0.010
regulation of nucleotide catabolic process GO:0030811 65 0.010
regulation of cell projection organization GO:0031344 175 0.010
cellular homeostasis GO:0019725 252 0.010
mapk cascade GO:0000165 140 0.010
regulation of nucleoside metabolic process GO:0009118 66 0.010
negative regulation of peptidase activity GO:0010466 38 0.010
response to ethanol GO:0045471 162 0.010
mrna processing GO:0006397 14 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
centrosome organization GO:0051297 1 0.010
regulation of protein oligomerization GO:0032459 2 0.010

Rps6kb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.048
muscular disease DOID:0080000 0 0.048
muscular dystrophy DOID:9884 0 0.048
disease of anatomical entity DOID:7 0 0.048
musculoskeletal system disease DOID:17 0 0.048
muscle tissue disease DOID:66 0 0.048
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
nervous system disease DOID:863 0 0.010