Rattus norvegicus

0 known processes

Cryba2

crystallin, beta A2

Cryba2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
g protein coupled receptor signaling pathway GO:0007186 242 0.275
cellular response to endogenous stimulus GO:0071495 377 0.256
cellular response to organic cyclic compound GO:0071407 202 0.237
response to glucocorticoid GO:0051384 223 0.226
sensory perception GO:0007600 101 0.225
regulation of cellular localization GO:0060341 263 0.214
neuron development GO:0048666 286 0.199
secretion by cell GO:0032940 248 0.197
positive regulation of signaling GO:0023056 270 0.189
regulation of secretion by cell GO:1903530 208 0.172
cellular cation homeostasis GO:0030003 180 0.161
ion transmembrane transport GO:0034220 365 0.161
regulation of hormone levels GO:0010817 187 0.159
response to peptide GO:1901652 292 0.154
Rat
transmembrane transport GO:0055085 412 0.143
cellular response to hormone stimulus GO:0032870 247 0.142
response to inorganic substance GO:0010035 377 0.141
cellular homeostasis GO:0019725 252 0.130
cellular response to oxygen containing compound GO:1901701 386 0.126
positive regulation of response to stimulus GO:0048584 285 0.121
cellular response to nitrogen compound GO:1901699 210 0.119
positive regulation of cell communication GO:0010647 271 0.116
intracellular signal transduction GO:0035556 314 0.116
response to corticosteroid GO:0031960 235 0.111
tissue development GO:0009888 252 0.111
Rat
rhythmic process GO:0048511 156 0.110
cellular response to lipid GO:0071396 201 0.108
hormone metabolic process GO:0042445 69 0.108
cell cell signaling GO:0007267 335 0.105
regulation of secretion GO:0051046 224 0.100
regulation of ion transport GO:0043269 245 0.096
regulation of phosphate metabolic process GO:0019220 349 0.095
cytosolic calcium ion homeostasis GO:0051480 140 0.094
central nervous system development GO:0007417 311 0.094
neurological system process GO:0050877 219 0.093
response to peptide hormone GO:0043434 278 0.093
Rat
inorganic ion transmembrane transport GO:0098660 229 0.091
positive regulation of secretion GO:0051047 140 0.091
response to metal ion GO:0010038 253 0.087
cellular response to organonitrogen compound GO:0071417 197 0.085
regulation of protein metabolic process GO:0051246 289 0.083
neuron differentiation GO:0030182 368 0.079
regulation of metal ion transport GO:0010959 118 0.078
divalent metal ion transport GO:0070838 132 0.078
secretion GO:0046903 307 0.078
cellular chemical homeostasis GO:0055082 247 0.074
calcium ion homeostasis GO:0055074 162 0.074
response to wounding GO:0009611 254 0.070
organelle organization GO:0006996 266 0.069
regulation of neurogenesis GO:0050767 247 0.067
positive regulation of transport GO:0051050 245 0.066
divalent inorganic cation transport GO:0072511 134 0.066
homeostatic process GO:0042592 331 0.064
response to nutrient levels GO:0031667 370 0.063
cation transmembrane transport GO:0098655 263 0.062
reproduction GO:0000003 245 0.061
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.059
programmed cell death GO:0012501 392 0.058
metal ion transport GO:0030001 289 0.058
carboxylic acid metabolic process GO:0019752 289 0.057
cellular component movement GO:0006928 248 0.057
inorganic cation transmembrane transport GO:0098662 202 0.057
cellular calcium ion homeostasis GO:0006874 160 0.056
positive regulation of molecular function GO:0044093 230 0.056
regulation of nucleotide biosynthetic process GO:0030808 47 0.053
multi organism reproductive process GO:0044703 262 0.052
regulation of apoptotic process GO:0042981 335 0.050
response to extracellular stimulus GO:0009991 380 0.050
positive regulation of hormone secretion GO:0046887 65 0.049
carbohydrate derivative metabolic process GO:1901135 346 0.048
regulation of multicellular organismal development GO:2000026 376 0.048
regulation of neuron differentiation GO:0045664 208 0.047
regulation of response to external stimulus GO:0032101 106 0.046
signal release GO:0023061 145 0.046
organic acid metabolic process GO:0006082 292 0.045
single organism biosynthetic process GO:0044711 342 0.045
chemical homeostasis GO:0048878 292 0.044
macromolecular complex assembly GO:0065003 273 0.044
proteolysis GO:0006508 175 0.043
single organism intracellular transport GO:1902582 166 0.043
response to ammonium ion GO:0060359 71 0.043
calcium ion transmembrane transport GO:0070588 70 0.042
cellular ion homeostasis GO:0006873 184 0.042
cellular divalent inorganic cation homeostasis GO:0072503 162 0.042
regulation of phosphorus metabolic process GO:0051174 349 0.042
response to ethanol GO:0045471 162 0.041
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.041
reproductive process GO:0022414 372 0.041
cellular metal ion homeostasis GO:0006875 172 0.041
protein complex biogenesis GO:0070271 263 0.041
hormone secretion GO:0046879 115 0.041
regulation of rna metabolic process GO:0051252 391 0.041
positive regulation of apoptotic process GO:0043065 154 0.040
neuron projection development GO:0031175 273 0.040
ribose phosphate metabolic process GO:0019693 235 0.040
response to bacterium GO:0009617 200 0.039
positive regulation of intracellular signal transduction GO:1902533 138 0.038
single organism reproductive process GO:0044702 297 0.038
positive regulation of signal transduction GO:0009967 175 0.038
macromolecular complex subunit organization GO:0043933 339 0.038
regulation of protein kinase activity GO:0045859 105 0.037
protein complex assembly GO:0006461 263 0.037
calcium ion import GO:0070509 22 0.037
response to acid chemical GO:0001101 222 0.037
regulation of calcium ion transport GO:0051924 77 0.037
response to radiation GO:0009314 137 0.036
positive regulation of protein metabolic process GO:0051247 178 0.036
positive regulation of catalytic activity GO:0043085 184 0.036
regulation of transcription dna templated GO:0006355 374 0.036
cellular amide metabolic process GO:0043603 44 0.035
protein phosphorylation GO:0006468 345 0.035
negative regulation of metabolic process GO:0009892 331 0.035
organonitrogen compound biosynthetic process GO:1901566 167 0.035
regulation of cellular component movement GO:0051270 150 0.034
positive regulation of biosynthetic process GO:0009891 319 0.034
cell motility GO:0048870 202 0.033
immune system process GO:0002376 204 0.033
nucleobase containing small molecule metabolic process GO:0055086 316 0.033
apoptotic process GO:0006915 381 0.032
behavior GO:0007610 205 0.032
multicellular organismal reproductive process GO:0048609 233 0.032
calcium ion transport GO:0006816 131 0.032
regulation of transmembrane transport GO:0034762 122 0.032
head development GO:0060322 247 0.032
response to estrogen GO:0043627 232 0.032
regulation of hormone secretion GO:0046883 106 0.032
response to camp GO:0051591 91 0.031
positive regulation of nervous system development GO:0051962 178 0.031
regulation of molecular function GO:0065009 398 0.031
regulation of neuron apoptotic process GO:0043523 83 0.030
response to hexose GO:0009746 144 0.030
response to external biotic stimulus GO:0043207 221 0.030
response to estradiol GO:0032355 164 0.030
cellular amine metabolic process GO:0044106 38 0.030
regulation of intracellular signal transduction GO:1902531 218 0.030
cation transport GO:0006812 382 0.030
cellular response to steroid hormone stimulus GO:0071383 93 0.030
tube development GO:0035295 89 0.030
cellular response to growth factor stimulus GO:0071363 162 0.029
cellular response to cytokine stimulus GO:0071345 127 0.029
divalent inorganic cation homeostasis GO:0072507 165 0.029
regulation of nervous system development GO:0051960 264 0.029
protein complex subunit organization GO:0071822 302 0.028
oxoacid metabolic process GO:0043436 290 0.028
regulation of programmed cell death GO:0043067 341 0.028
blood circulation GO:0008015 183 0.028
metal ion homeostasis GO:0055065 186 0.028
positive regulation of cellular biosynthetic process GO:0031328 295 0.028
positive regulation of secretion by cell GO:1903532 128 0.028
glucose homeostasis GO:0042593 75 0.027
ribose phosphate biosynthetic process GO:0046390 87 0.027
positive regulation of cell differentiation GO:0045597 217 0.027
intracellular transport GO:0046907 185 0.027
anatomical structure morphogenesis GO:0009653 298 0.027
nucleoside phosphate biosynthetic process GO:1901293 102 0.027
establishment of protein localization GO:0045184 141 0.027
protein homooligomerization GO:0051260 91 0.026
jak stat cascade GO:0007259 26 0.026
response to glucose GO:0009749 136 0.026
vesicle mediated transport GO:0016192 181 0.026
response to organophosphorus GO:0046683 102 0.026
rna biosynthetic process GO:0032774 380 0.026
cellular hormone metabolic process GO:0034754 49 0.026
regulation of signal transduction GO:0009966 318 0.026
steroid metabolic process GO:0008202 73 0.026
response to carbohydrate GO:0009743 183 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
cell migration GO:0016477 197 0.026
second messenger mediated signaling GO:0019932 51 0.026
regulation of catalytic activity GO:0050790 304 0.025
cognition GO:0050890 92 0.025
negative regulation of transport GO:0051051 136 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
cellular response to peptide hormone stimulus GO:0071375 120 0.025
positive regulation of ion transport GO:0043270 94 0.025
sensory perception of pain GO:0019233 73 0.025
response to hypoxia GO:0001666 231 0.025
inflammatory response GO:0006954 150 0.025
sex differentiation GO:0007548 113 0.025
purine nucleotide biosynthetic process GO:0006164 83 0.024
regulation of cell development GO:0060284 263 0.024
protein oligomerization GO:0051259 191 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.024
regulation of cell projection organization GO:0031344 175 0.024
ion homeostasis GO:0050801 212 0.024
cellular response to peptide GO:1901653 133 0.024
regulation of system process GO:0044057 208 0.024
dorsal ventral axon guidance GO:0033563 1 0.024
positive regulation of phosphorylation GO:0042327 177 0.024
synaptic transmission GO:0007268 235 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
response to monosaccharide GO:0034284 159 0.023
cellular lipid metabolic process GO:0044255 208 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
positive regulation of peptide secretion GO:0002793 52 0.023
response to decreased oxygen levels GO:0036293 237 0.023
response to oxygen levels GO:0070482 265 0.023
nucleotide metabolic process GO:0009117 279 0.023
insulin secretion GO:0030073 69 0.023
defense response GO:0006952 194 0.023
response to cytokine GO:0034097 215 0.023
glutamate receptor signaling pathway GO:0007215 43 0.023
response to molecule of bacterial origin GO:0002237 194 0.023
response to alkaloid GO:0043279 132 0.023
organophosphate biosynthetic process GO:0090407 143 0.023
neuron death GO:0070997 127 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.022
developmental growth involved in morphogenesis GO:0060560 33 0.022
action potential GO:0001508 54 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.022
positive regulation of cellular protein metabolic process GO:0032270 167 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
single organism catabolic process GO:0044712 283 0.021
lipid metabolic process GO:0006629 283 0.021
peptide transport GO:0015833 97 0.021
macromolecule localization GO:0033036 252 0.021
regulation of peptide secretion GO:0002791 82 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
positive regulation of protein modification process GO:0031401 142 0.020
response to light stimulus GO:0009416 52 0.020
cell projection organization GO:0030030 302 0.020
aging GO:0007568 241 0.020
rna metabolic process GO:0016070 406 0.020
response to retinoic acid GO:0032526 63 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
monovalent inorganic cation transport GO:0015672 172 0.020
cation homeostasis GO:0055080 195 0.020
organophosphate metabolic process GO:0019637 370 0.020
nucleotide biosynthetic process GO:0009165 98 0.019
response to lipopolysaccharide GO:0032496 191 0.019
regulation of transferase activity GO:0051338 123 0.019
positive regulation of protein phosphorylation GO:0001934 135 0.019
negative regulation of protein metabolic process GO:0051248 114 0.019
ribonucleotide biosynthetic process GO:0009260 85 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
cellular ketone metabolic process GO:0042180 51 0.019
nucleic acid templated transcription GO:0097659 379 0.019
sensory perception of light stimulus GO:0050953 3 0.019
positive regulation of transferase activity GO:0051347 81 0.018
multicellular organismal response to stress GO:0033555 25 0.018
amide transport GO:0042886 105 0.018
anion transport GO:0006820 178 0.018
cell adhesion GO:0007155 110 0.018
response to transition metal nanoparticle GO:1990267 122 0.018
amine transport GO:0015837 57 0.018
purine ribonucleotide biosynthetic process GO:0009152 81 0.018
response to toxic substance GO:0009636 133 0.017
regulation of axonogenesis GO:0050770 37 0.017
purine containing compound metabolic process GO:0072521 253 0.017
protein heterooligomerization GO:0051291 89 0.017
muscle system process GO:0003012 115 0.017
negative regulation of cell communication GO:0010648 158 0.017
carbohydrate homeostasis GO:0033500 75 0.017
cellular component biogenesis GO:0044085 368 0.017
brain development GO:0007420 247 0.017
sexual reproduction GO:0019953 148 0.017
multi multicellular organism process GO:0044706 138 0.017
circadian rhythm GO:0007623 88 0.017
response to growth factor GO:0070848 189 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
amine metabolic process GO:0009308 38 0.017
transmission of nerve impulse GO:0019226 42 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
carbohydrate derivative biosynthetic process GO:1901137 124 0.017
cytoskeleton organization GO:0007010 111 0.017
growth GO:0040007 165 0.016
peptide secretion GO:0002790 86 0.016
positive regulation of response to external stimulus GO:0032103 51 0.016
catabolic process GO:0009056 351 0.016
regulation of membrane potential GO:0042391 110 0.016
regulation of protein modification process GO:0031399 194 0.016
synapse organization GO:0050808 46 0.016
regulation of immune system process GO:0002682 123 0.016
positive regulation of cell death GO:0010942 184 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.016
multicellular organism reproduction GO:0032504 233 0.016
purine containing compound biosynthetic process GO:0072522 85 0.016
positive regulation of developmental process GO:0051094 283 0.016
organic cyclic compound catabolic process GO:1901361 175 0.015
nitrogen compound transport GO:0071705 229 0.015
negative regulation of nervous system development GO:0051961 79 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
regulation of cellular component organization GO:0051128 368 0.015
response to temperature stimulus GO:0009266 94 0.015
protein localization GO:0008104 191 0.015
regulation of neurological system process GO:0031644 43 0.015
regulation of anatomical structure size GO:0090066 135 0.015
salivary gland development GO:0007431 3 0.015
cellular response to insulin stimulus GO:0032869 81 0.015
peptidyl amino acid modification GO:0018193 126 0.015
cellular response to stress GO:0033554 269 0.015
cellular component assembly GO:0022607 360 0.015
response to dexamethasone GO:0071548 49 0.015
sodium ion transport GO:0006814 82 0.015
gamete generation GO:0007276 124 0.014
visual perception GO:0007601 3 0.014
positive regulation of cell development GO:0010720 176 0.014
response to vitamin GO:0033273 131 0.014
eye morphogenesis GO:0048592 4 0.014
biological adhesion GO:0022610 110 0.014
sensory organ development GO:0007423 74 0.014
Rat
regulation of camp metabolic process GO:0030814 43 0.014
positive regulation of peptide hormone secretion GO:0090277 50 0.014
development of primary sexual characteristics GO:0045137 107 0.014
regulation of cell proliferation GO:0042127 359 0.014
locomotion GO:0040011 237 0.013
camp biosynthetic process GO:0006171 47 0.013
regulation of neuron projection development GO:0010975 161 0.013
negative regulation of cell death GO:0060548 229 0.013
regulation of organelle organization GO:0033043 80 0.013
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.013
negative regulation of gene expression GO:0010629 199 0.013
positive regulation of gene expression GO:0010628 244 0.013
activation of protein kinase activity GO:0032147 47 0.013
cellular response to inorganic substance GO:0071241 65 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
positive regulation of calcium ion transport GO:0051928 36 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
negative regulation of signaling GO:0023057 157 0.013
cellular response to alcohol GO:0097306 87 0.013
cofactor metabolic process GO:0051186 95 0.013
retina morphogenesis in camera type eye GO:0060042 1 0.013
cellular catabolic process GO:0044248 295 0.013
multicellular organismal signaling GO:0035637 44 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
forebrain development GO:0030900 98 0.013
regulation of kinase activity GO:0043549 117 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.013
cellular response to ammonium ion GO:0071242 17 0.013
cyclic nucleotide metabolic process GO:0009187 80 0.013
regulation of neuron death GO:1901214 115 0.012
spermatogenesis GO:0007283 99 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
male gamete generation GO:0048232 99 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
coenzyme metabolic process GO:0006732 86 0.012
regulation of synaptic transmission GO:0050804 141 0.012
membrane organization GO:0061024 94 0.012
regulation of cell differentiation GO:0045595 320 0.012
response to purine containing compound GO:0014074 126 0.012
sequestering of calcium ion GO:0051208 8 0.012
regulation of cell morphogenesis GO:0022604 77 0.012
adult locomotory behavior GO:0008344 4 0.012
response to hydrogen peroxide GO:0042542 89 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
cellular amino acid metabolic process GO:0006520 107 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
regulation of defense response GO:0031347 68 0.012
negative regulation of neuron differentiation GO:0045665 62 0.012
organic substance catabolic process GO:1901575 316 0.012
spinal cord development GO:0021510 27 0.012
peptide hormone secretion GO:0030072 84 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
alcohol metabolic process GO:0006066 77 0.011
glucagon secretion GO:0070091 5 0.011
regulation of glucagon secretion GO:0070092 5 0.011
neuron projection morphogenesis GO:0048812 122 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
cytoplasmic transport GO:0016482 115 0.011
cyclic purine nucleotide metabolic process GO:0052652 62 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
dna metabolic process GO:0006259 96 0.011
taxis GO:0042330 67 0.011
single organism behavior GO:0044708 130 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
response to electrical stimulus GO:0051602 56 0.011
response to ketone GO:1901654 182 0.011
cell projection morphogenesis GO:0048858 123 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
peptide metabolic process GO:0006518 32 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
hormone transport GO:0009914 121 0.011
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.011
regulation of cell adhesion GO:0030155 52 0.011
muscle contraction GO:0006936 88 0.011
protein transport GO:0015031 132 0.011
camera type eye development GO:0043010 48 0.011
Rat
protein maturation GO:0051604 68 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
cellular response to ketone GO:1901655 51 0.011
axon choice point recognition GO:0016198 2 0.011
cellular response to hexose stimulus GO:0071331 65 0.011
regulation of locomotion GO:0040012 148 0.010
negative regulation of biosynthetic process GO:0009890 168 0.010
response to amine GO:0014075 46 0.010
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.010
meiotic cell cycle process GO:1903046 3 0.010
reproductive system development GO:0061458 128 0.010
wound healing GO:0042060 122 0.010
organelle localization GO:0051640 55 0.010
positive regulation of immune system process GO:0002684 90 0.010
gonad development GO:0008406 104 0.010
neuronal action potential GO:0019228 35 0.010
cardiovascular system development GO:0072358 134 0.010
calcium ion dependent exocytosis GO:0017156 16 0.010
response to oxidative stress GO:0006979 186 0.010
heart development GO:0007507 72 0.010
response to insulin GO:0032868 133 0.010
cellular response to glucose stimulus GO:0071333 65 0.010
positive regulation of protein kinase activity GO:0045860 73 0.010
response to starvation GO:0042594 59 0.010
sequestering of metal ion GO:0051238 9 0.010
negative regulation of neuron death GO:1901215 69 0.010
mapk cascade GO:0000165 140 0.010
camera type eye morphogenesis GO:0048593 2 0.010
positive regulation of defense response GO:0031349 37 0.010

Cryba2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.073
disease of anatomical entity DOID:7 0 0.073
nervous system disease DOID:863 0 0.073
retinal disease DOID:5679 0 0.049
retinal degeneration DOID:8466 0 0.049
eye and adnexa disease DOID:1492 0 0.049
eye disease DOID:5614 0 0.049
retinitis pigmentosa DOID:10584 0 0.041
musculoskeletal system disease DOID:17 0 0.010