Rattus norvegicus

52 known processes

Csf2

colony stimulating factor 2 (granulocyte-macrophage)

(Aliases: Gm-csf,Gmcsf)

Csf2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of molecular function GO:0065009 398 0.089
programmed cell death GO:0012501 392 0.077
intracellular signal transduction GO:0035556 314 0.076
response to extracellular stimulus GO:0009991 380 0.075
regulation of cell proliferation GO:0042127 359 0.070
response to mechanical stimulus GO:0009612 134 0.066
divalent inorganic cation homeostasis GO:0072507 165 0.063
cation transmembrane transport GO:0098655 263 0.060
regulation of programmed cell death GO:0043067 341 0.058
response to peptide hormone GO:0043434 278 0.057
regulation of secretion by cell GO:1903530 208 0.056
macromolecule localization GO:0033036 252 0.056
regulation of neurogenesis GO:0050767 247 0.055
response to nutrient levels GO:0031667 370 0.053
positive regulation of multicellular organismal process GO:0051240 387 0.050
response to cytokine GO:0034097 215 0.048
cell cell signaling GO:0007267 335 0.047
reproductive process GO:0022414 372 0.046
secretion by cell GO:0032940 248 0.046
positive regulation of transport GO:0051050 245 0.046
localization of cell GO:0051674 202 0.045
regulation of catalytic activity GO:0050790 304 0.044
positive regulation of cell differentiation GO:0045597 217 0.043
homeostatic process GO:0042592 331 0.043
secretion GO:0046903 307 0.043
cell migration GO:0016477 197 0.043
positive regulation of biosynthetic process GO:0009891 319 0.042
positive regulation of cell proliferation GO:0008284 249 0.042
positive regulation of developmental process GO:0051094 283 0.041
cellular response to growth factor stimulus GO:0071363 162 0.040
positive regulation of signaling GO:0023056 270 0.039
brain development GO:0007420 247 0.039
response to growth factor GO:0070848 189 0.038
positive regulation of cell communication GO:0010647 271 0.037
regulation of intracellular signal transduction GO:1902531 218 0.036
organic anion transport GO:0015711 132 0.036
forebrain development GO:0030900 98 0.036
nitrogen compound transport GO:0071705 229 0.036
ras protein signal transduction GO:0007265 29 0.035
response to bacterium GO:0009617 200 0.035
response to biotic stimulus GO:0009607 226 0.035
positive regulation of response to stimulus GO:0048584 285 0.035
regulation of ion transport GO:0043269 245 0.034
regulation of secretion GO:0051046 224 0.034
neuron development GO:0048666 286 0.034
multi organism reproductive process GO:0044703 262 0.034
regulation of hormone levels GO:0010817 187 0.033
cellular calcium ion homeostasis GO:0006874 160 0.033
signal release GO:0023061 145 0.033
chemical homeostasis GO:0048878 292 0.033
calcium ion homeostasis GO:0055074 162 0.033
regulation of cell motility GO:2000145 131 0.032
negative regulation of transport GO:0051051 136 0.032
cellular homeostasis GO:0019725 252 0.032
defense response GO:0006952 194 0.032
nucleic acid templated transcription GO:0097659 379 0.032
cellular chemical homeostasis GO:0055082 247 0.032
response to peptide GO:1901652 292 0.032
eye morphogenesis GO:0048592 4 0.031
potassium ion transport GO:0006813 97 0.031
negative regulation of cell communication GO:0010648 158 0.031
negative regulation of secretion by cell GO:1903531 72 0.031
positive regulation of ion transport GO:0043270 94 0.031
negative regulation of cell death GO:0060548 229 0.030
macromolecular complex assembly GO:0065003 273 0.030
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.030
response to corticosteroid GO:0031960 235 0.029
regulation of anatomical structure size GO:0090066 135 0.029
regulation of apoptotic process GO:0042981 335 0.029
g protein coupled receptor signaling pathway GO:0007186 242 0.028
response to monosaccharide GO:0034284 159 0.028
organic acid biosynthetic process GO:0016053 83 0.027
regulation of neuron differentiation GO:0045664 208 0.027
positive regulation of cell development GO:0010720 176 0.027
response to other organism GO:0051707 220 0.026
reactive nitrogen species metabolic process GO:2001057 1 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
reproductive system development GO:0061458 128 0.025
behavior GO:0007610 205 0.025
cell motility GO:0048870 202 0.025
regulation of cellular localization GO:0060341 263 0.025
response to lipopolysaccharide GO:0032496 191 0.025
central nervous system development GO:0007417 311 0.025
synaptic transmission GO:0007268 235 0.025
regulation of signal transduction GO:0009966 318 0.025
response to hexose GO:0009746 144 0.024
cellular amino acid metabolic process GO:0006520 107 0.024
organic substance catabolic process GO:1901575 316 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
cellular cation homeostasis GO:0030003 180 0.024
positive regulation of secretion GO:0051047 140 0.024
negative regulation of response to stimulus GO:0048585 155 0.024
regulation of cell projection organization GO:0031344 175 0.023
regulation of rna metabolic process GO:0051252 391 0.023
small gtpase mediated signal transduction GO:0007264 36 0.023
regulation of ion transmembrane transport GO:0034765 121 0.023
regulation of system process GO:0044057 208 0.023
positive regulation of signal transduction GO:0009967 175 0.022
response to fatty acid GO:0070542 65 0.022
negative regulation of neuron projection development GO:0010977 46 0.022
negative regulation of signaling GO:0023057 157 0.022
regulation of rna biosynthetic process GO:2001141 381 0.022
response to glucocorticoid GO:0051384 223 0.022
regulation of cell differentiation GO:0045595 320 0.021
cation transport GO:0006812 382 0.021
negative regulation of cellular component organization GO:0051129 83 0.021
negative regulation of cell projection organization GO:0031345 50 0.021
regulation of cellular component organization GO:0051128 368 0.021
metal ion homeostasis GO:0055065 186 0.021
female pregnancy GO:0007565 122 0.021
negative regulation of cellular protein metabolic process GO:0032269 106 0.021
hormone secretion GO:0046879 115 0.020
monocarboxylic acid metabolic process GO:0032787 152 0.020
monovalent inorganic cation transport GO:0015672 172 0.020
regeneration GO:0031099 163 0.019
protein phosphorylation GO:0006468 345 0.019
cell projection organization GO:0030030 302 0.019
response to external biotic stimulus GO:0043207 221 0.019
ion transmembrane transport GO:0034220 365 0.019
proteolysis GO:0006508 175 0.019
lipid metabolic process GO:0006629 283 0.019
regulation of response to stress GO:0080134 126 0.019
innate immune response GO:0045087 35 0.019
cellular response to oxygen containing compound GO:1901701 386 0.018
cytosolic calcium ion homeostasis GO:0051480 140 0.018
regulation of transcription dna templated GO:0006355 374 0.018
regulation of locomotion GO:0040012 148 0.018
neurological system process GO:0050877 219 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
protein complex assembly GO:0006461 263 0.018
negative regulation of secretion GO:0051048 82 0.018
negative regulation of protein metabolic process GO:0051248 114 0.017
lipid localization GO:0010876 62 0.017
positive regulation of molecular function GO:0044093 230 0.017
circulatory system process GO:0003013 183 0.017
response to nutrient GO:0007584 248 0.017
apoptotic process GO:0006915 381 0.017
head development GO:0060322 247 0.017
lipid transport GO:0006869 61 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
regulation of cell development GO:0060284 263 0.017
negative regulation of nervous system development GO:0051961 79 0.017
sensory perception of pain GO:0019233 73 0.017
response to molecule of bacterial origin GO:0002237 194 0.017
ion homeostasis GO:0050801 212 0.016
regulation of nucleic acid templated transcription GO:1903506 380 0.016
regulation of multicellular organismal development GO:2000026 376 0.016
neuron differentiation GO:0030182 368 0.016
anion transport GO:0006820 178 0.016
negative regulation of neuron differentiation GO:0045665 62 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.016
camera type eye morphogenesis GO:0048593 2 0.015
response to wounding GO:0009611 254 0.015
regulation of nervous system development GO:0051960 264 0.015
regulation of cellular component movement GO:0051270 150 0.015
cation homeostasis GO:0055080 195 0.015
transcription dna templated GO:0006351 377 0.015
cellular response to endogenous stimulus GO:0071495 377 0.015
negative regulation of metabolic process GO:0009892 331 0.015
catabolic process GO:0009056 351 0.015
positive regulation of blood circulation GO:1903524 65 0.015
single organism biosynthetic process GO:0044711 342 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
single organism reproductive process GO:0044702 297 0.015
response to glucose GO:0009749 136 0.015
sensory perception GO:0007600 101 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
positive regulation of cell death GO:0010942 184 0.014
regulation of protein metabolic process GO:0051246 289 0.014
immune response GO:0006955 104 0.014
jak stat cascade GO:0007259 26 0.014
carboxylic acid metabolic process GO:0019752 289 0.014
negative regulation of cell development GO:0010721 82 0.014
cellular potassium ion transport GO:0071804 72 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
gland development GO:0048732 155 0.014
regulation of transmembrane transport GO:0034762 122 0.014
response to estradiol GO:0032355 164 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
response to carbohydrate GO:0009743 183 0.014
negative regulation of molecular function GO:0044092 133 0.014
macromolecular complex subunit organization GO:0043933 339 0.013
negative regulation of neurogenesis GO:0050768 78 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.013
regulation of neuron projection development GO:0010975 161 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
regulation of cellular ketone metabolic process GO:0010565 27 0.013
regulation of dendrite development GO:0050773 59 0.013
organic acid metabolic process GO:0006082 292 0.013
response to alkaloid GO:0043279 132 0.013
glucose homeostasis GO:0042593 75 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
cellular response to glucose stimulus GO:0071333 65 0.013
positive regulation of secretion by cell GO:1903532 128 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.012
metal ion transport GO:0030001 289 0.012
cellular component morphogenesis GO:0032989 155 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
regulation of mapk cascade GO:0043408 116 0.012
cellular ketone metabolic process GO:0042180 51 0.012
cellular component movement GO:0006928 248 0.012
organic acid transport GO:0015849 116 0.012
regulation of calcium ion transport GO:0051924 77 0.012
aging GO:0007568 241 0.012
protein complex subunit organization GO:0071822 302 0.012
glial cell migration GO:0008347 11 0.012
mesoderm development GO:0007498 2 0.012
multicellular organism reproduction GO:0032504 233 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
purinergic receptor signaling pathway GO:0035587 10 0.012
hormone metabolic process GO:0042445 69 0.012
vascular process in circulatory system GO:0003018 96 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.012
organ formation GO:0048645 3 0.012
peptide transport GO:0015833 97 0.012
positive regulation of gene expression GO:0010628 244 0.011
organic hydroxy compound transport GO:0015850 77 0.011
cellular response to external stimulus GO:0071496 118 0.011
hepaticobiliary system development GO:0061008 90 0.011
axon choice point recognition GO:0016198 2 0.011
negative regulation of cellular metabolic process GO:0031324 281 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
regulation of cell migration GO:0030334 128 0.011
regulation of tube size GO:0035150 89 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
respiratory gaseous exchange GO:0007585 4 0.011
amine metabolic process GO:0009308 38 0.011
regulation of insulin secretion GO:0050796 65 0.010
reproduction GO:0000003 245 0.010
regulation of blood vessel size GO:0050880 89 0.010
retina morphogenesis in camera type eye GO:0060042 1 0.010
calcium ion transport GO:0006816 131 0.010
endomembrane system organization GO:0010256 48 0.010
transmembrane transport GO:0055085 412 0.010
carboxylic acid transport GO:0046942 115 0.010
amide transport GO:0042886 105 0.010
sexual reproduction GO:0019953 148 0.010
nucleotide metabolic process GO:0009117 279 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
regulation of protein phosphorylation GO:0001932 183 0.010
response to oxygen levels GO:0070482 265 0.010
negative regulation of signal transduction GO:0009968 83 0.010
response to amine GO:0014075 46 0.010
cellular component assembly GO:0022607 360 0.010
male gamete generation GO:0048232 99 0.010

Csf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
nervous system disease DOID:863 0 0.047
sensory system disease DOID:0050155 0 0.030
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013