Rattus norvegicus

0 known processes

Espl1

extra spindle pole bodies homolog 1 (S. cerevisiae)

Espl1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
chromosome segregation GO:0007059 2 0.133
mitotic sister chromatid separation GO:0051306 1 0.120
regulation of proteasomal protein catabolic process GO:0061136 4 0.112
mitotic sister chromatid segregation GO:0000070 1 0.108
regulation of protein metabolic process GO:0051246 289 0.078
sister chromatid segregation GO:0000819 1 0.065
mitotic spindle organization GO:0007052 2 0.061
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.057
spindle organization GO:0007051 2 0.054
regulation of protein modification process GO:0031399 194 0.052
cell cycle GO:0007049 101 0.052
metaphase anaphase transition of cell cycle GO:0044784 1 0.051
regulation of chromosome segregation GO:0051983 1 0.046
regulation of cellular component organization GO:0051128 368 0.046
centrosome organization GO:0051297 1 0.046
regulation of cellular protein metabolic process GO:0032268 267 0.046
negative regulation of macromolecule metabolic process GO:0010605 260 0.045
organelle organization GO:0006996 266 0.043
organic substance catabolic process GO:1901575 316 0.042
regulation of phosphorus metabolic process GO:0051174 349 0.041
negative regulation of gene expression GO:0010629 199 0.038
regulation of phosphorylation GO:0042325 248 0.037
cellular catabolic process GO:0044248 295 0.037
positive regulation of cellular protein metabolic process GO:0032270 167 0.036
negative regulation of cellular component organization GO:0051129 83 0.035
metaphase plate congression GO:0051310 1 0.035
regulation of protein phosphorylation GO:0001932 183 0.035
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.035
microtubule organizing center organization GO:0031023 1 0.034
centrosome cycle GO:0007098 1 0.034
cellular amino acid metabolic process GO:0006520 107 0.034
regulation of neurogenesis GO:0050767 247 0.033
multicellular organismal reproductive process GO:0048609 233 0.033
positive regulation of protein metabolic process GO:0051247 178 0.033
regulation of sister chromatid segregation GO:0033045 1 0.033
protein complex biogenesis GO:0070271 263 0.033
negative regulation of cellular protein metabolic process GO:0032269 106 0.033
regulation of cell differentiation GO:0045595 320 0.032
cellular component assembly GO:0022607 360 0.032
cellular amine metabolic process GO:0044106 38 0.032
regulation of molecular function GO:0065009 398 0.031
negative regulation of metabolic process GO:0009892 331 0.031
regulation of synapse maturation GO:0090128 2 0.031
single organism organelle organization GO:1902589 180 0.030
meiotic cell cycle process GO:1903046 3 0.030
macromolecular complex assembly GO:0065003 273 0.030
cellular response to stress GO:0033554 269 0.030
ras protein signal transduction GO:0007265 29 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
nucleobase containing small molecule metabolic process GO:0055086 316 0.028
cellular response to oxygen containing compound GO:1901701 386 0.028
apoptotic process GO:0006915 381 0.028
regulation of cell projection organization GO:0031344 175 0.028
cellular component biogenesis GO:0044085 368 0.028
regulation of programmed cell death GO:0043067 341 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
programmed cell death GO:0012501 392 0.026
small gtpase mediated signal transduction GO:0007264 36 0.026
reproduction GO:0000003 245 0.026
protein complex assembly GO:0006461 263 0.026
protein complex subunit organization GO:0071822 302 0.026
positive regulation of developmental process GO:0051094 283 0.026
cellular component movement GO:0006928 248 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.025
regulation of multicellular organismal development GO:2000026 376 0.025
negative regulation of cell death GO:0060548 229 0.025
chromosome organization GO:0051276 36 0.025
regulation of transcription dna templated GO:0006355 374 0.025
intracellular signal transduction GO:0035556 314 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.023
regulation of phosphate metabolic process GO:0019220 349 0.023
regulation of neuron differentiation GO:0045664 208 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
amine metabolic process GO:0009308 38 0.023
regulation of nervous system development GO:0051960 264 0.023
regulation of neuron projection development GO:0010975 161 0.023
regulation of cell proliferation GO:0042127 359 0.023
organic acid metabolic process GO:0006082 292 0.023
positive regulation of protein phosphorylation GO:0001934 135 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
brain development GO:0007420 247 0.022
aging GO:0007568 241 0.022
regulation of catalytic activity GO:0050790 304 0.022
regulation of apoptotic process GO:0042981 335 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.021
response to cytokine GO:0034097 215 0.021
mitotic cell cycle process GO:1903047 35 0.021
cellular macromolecule catabolic process GO:0044265 29 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
maintenance of location GO:0051235 17 0.020
rna metabolic process GO:0016070 406 0.020
negative regulation of programmed cell death GO:0043069 183 0.020
regulation of cell cycle GO:0051726 73 0.019
regulation of protein serine threonine kinase activity GO:0071900 64 0.019
positive regulation of gene expression GO:0010628 244 0.019
negative regulation of phosphate metabolic process GO:0045936 80 0.019
protein localization GO:0008104 191 0.019
cytoskeleton organization GO:0007010 111 0.019
catabolic process GO:0009056 351 0.019
regulation of mitotic sister chromatid separation GO:0010965 1 0.019
positive regulation of protein modification process GO:0031401 142 0.019
gastrulation GO:0007369 2 0.019
macromolecule catabolic process GO:0009057 58 0.018
nucleotide metabolic process GO:0009117 279 0.018
neuron differentiation GO:0030182 368 0.018
regulation of cell development GO:0060284 263 0.018
regulation of protein kinase activity GO:0045859 105 0.018
positive regulation of nervous system development GO:0051962 178 0.018
central nervous system development GO:0007417 311 0.018
cell cycle checkpoint GO:0000075 2 0.017
negative regulation of neurogenesis GO:0050768 78 0.017
cell cycle process GO:0022402 57 0.017
single organism catabolic process GO:0044712 283 0.017
regulation of transferase activity GO:0051338 123 0.017
chromosome separation GO:0051304 1 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
nucleic acid templated transcription GO:0097659 379 0.017
regulation of mitotic sister chromatid segregation GO:0033047 1 0.017
regulation of signal transduction GO:0009966 318 0.017
sexual reproduction GO:0019953 148 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
regeneration GO:0031099 163 0.016
response to acid chemical GO:0001101 222 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
tissue development GO:0009888 252 0.016
gamete generation GO:0007276 124 0.016
negative regulation of nuclear division GO:0051784 1 0.016
meiosis i GO:0007127 2 0.016
microtubule polymerization or depolymerization GO:0031109 13 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
cellular protein localization GO:0034613 122 0.016
negative regulation of cell differentiation GO:0045596 99 0.015
dna metabolic process GO:0006259 96 0.015
vesicle mediated transport GO:0016192 181 0.015
carboxylic acid metabolic process GO:0019752 289 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
mitotic cell cycle GO:0000278 49 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
negative regulation of cell cycle phase transition GO:1901988 4 0.015
organophosphate metabolic process GO:0019637 370 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.015
double strand break repair GO:0006302 1 0.015
positive regulation of molecular function GO:0044093 230 0.015
response to ethanol GO:0045471 162 0.015
negative regulation of developmental process GO:0051093 125 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
positive regulation of synaptic plasticity GO:0031915 3 0.015
microtubule anchoring GO:0034453 1 0.014
proteolysis GO:0006508 175 0.014
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
multi organism reproductive process GO:0044703 262 0.014
regulation of growth GO:0040008 105 0.014
response to extracellular stimulus GO:0009991 380 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
synaptic transmission GO:0007268 235 0.014
histone serine phosphorylation GO:0035404 1 0.014
cellular ketone metabolic process GO:0042180 51 0.014
neurological system process GO:0050877 219 0.014
dna packaging GO:0006323 4 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
regulation of nucleic acid templated transcription GO:1903506 380 0.014
cellular macromolecule localization GO:0070727 122 0.013
neuron development GO:0048666 286 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
neuron projection development GO:0031175 273 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
regulation of synaptic transmission GO:0050804 141 0.013
cell cell signaling GO:0007267 335 0.012
single organism reproductive process GO:0044702 297 0.012
purine containing compound metabolic process GO:0072521 253 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
regulation of kinase activity GO:0043549 117 0.012
response to oxygen levels GO:0070482 265 0.012
transcription dna templated GO:0006351 377 0.012
protein phosphorylation GO:0006468 345 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
response to glucocorticoid GO:0051384 223 0.012
asymmetric protein localization GO:0008105 2 0.012
cellular protein complex assembly GO:0043623 44 0.012
rna biosynthetic process GO:0032774 380 0.011
response to nutrient levels GO:0031667 370 0.011
male gamete generation GO:0048232 99 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.011
single organism biosynthetic process GO:0044711 342 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.011
cellular protein catabolic process GO:0044257 19 0.011
regulation of organelle organization GO:0033043 80 0.011
multicellular organism reproduction GO:0032504 233 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
cell projection organization GO:0030030 302 0.011
intracellular transport GO:0046907 185 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
regulation of small gtpase mediated signal transduction GO:0051056 48 0.011
head development GO:0060322 247 0.011
epithelium development GO:0060429 96 0.011
positive regulation of proteasomal protein catabolic process GO:1901800 3 0.011
response to hypoxia GO:0001666 231 0.011
response to decreased oxygen levels GO:0036293 237 0.011
spermatogenesis GO:0007283 99 0.011
axis specification GO:0009798 4 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.010
anatomical structure morphogenesis GO:0009653 298 0.010
positive regulation of biosynthetic process GO:0009891 319 0.010
positive regulation of rna metabolic process GO:0051254 203 0.010
muscle cell proliferation GO:0033002 84 0.010
negative regulation of protein maturation GO:1903318 47 0.010
single organism membrane organization GO:0044802 74 0.010
mitotic cell cycle checkpoint GO:0007093 1 0.010

Espl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org