Rattus norvegicus

34 known processes

Tspan8

tetraspanin 8

(Aliases: CO-29,Tm4sf3)

Tspan8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
programmed cell death GO:0012501 392 0.177
negative regulation of metabolic process GO:0009892 331 0.117
regulation of programmed cell death GO:0043067 341 0.112
single organism biosynthetic process GO:0044711 342 0.107
apoptotic process GO:0006915 381 0.097
regulation of cell proliferation GO:0042127 359 0.093
Rat
regulation of phosphate metabolic process GO:0019220 349 0.085
regulation of molecular function GO:0065009 398 0.084
positive regulation of cell communication GO:0010647 271 0.079
intracellular signal transduction GO:0035556 314 0.078
nucleobase containing small molecule metabolic process GO:0055086 316 0.076
cation transport GO:0006812 382 0.071
positive regulation of biosynthetic process GO:0009891 319 0.066
metal ion transport GO:0030001 289 0.065
organic acid metabolic process GO:0006082 292 0.064
regulation of multicellular organismal development GO:2000026 376 0.061
positive regulation of multicellular organismal process GO:0051240 387 0.061
transmembrane transport GO:0055085 412 0.059
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.058
lipid metabolic process GO:0006629 283 0.056
response to wounding GO:0009611 254 0.054
cation transmembrane transport GO:0098655 263 0.054
response to inorganic substance GO:0010035 377 0.052
Rat
protein complex biogenesis GO:0070271 263 0.052
regulation of catalytic activity GO:0050790 304 0.051
negative regulation of macromolecule metabolic process GO:0010605 260 0.051
cellular response to stress GO:0033554 269 0.050
regulation of apoptotic process GO:0042981 335 0.050
positive regulation of transport GO:0051050 245 0.050
central nervous system development GO:0007417 311 0.048
Rat
monocarboxylic acid metabolic process GO:0032787 152 0.046
divalent inorganic cation transport GO:0072511 134 0.046
positive regulation of cell proliferation GO:0008284 249 0.045
positive regulation of programmed cell death GO:0043068 157 0.045
regulation of ion transport GO:0043269 245 0.045
platelet derived growth factor production GO:0090360 2 0.044
nucleotide metabolic process GO:0009117 279 0.044
cellular ion homeostasis GO:0006873 184 0.043
regulation of protein metabolic process GO:0051246 289 0.043
tissue development GO:0009888 252 0.043
regulation of signal transduction GO:0009966 318 0.042
ion transmembrane transport GO:0034220 365 0.041
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.041
glomerular mesangium development GO:0072109 4 0.041
inorganic cation transmembrane transport GO:0098662 202 0.041
protein complex assembly GO:0006461 263 0.040
positive regulation of cell death GO:0010942 184 0.040
regulation of rna biosynthetic process GO:2001141 381 0.040
carboxylic acid metabolic process GO:0019752 289 0.040
negative regulation of gene expression GO:0010629 199 0.040
regulation of transcription dna templated GO:0006355 374 0.040
regulation of phosphorus metabolic process GO:0051174 349 0.039
rna metabolic process GO:0016070 406 0.039
positive regulation of developmental process GO:0051094 283 0.039
g protein coupled receptor signaling pathway GO:0007186 242 0.039
transcription dna templated GO:0006351 377 0.039
nitrogen compound transport GO:0071705 229 0.039
regulation of rna metabolic process GO:0051252 391 0.038
regulation of nucleic acid templated transcription GO:1903506 380 0.038
cellular response to oxygen containing compound GO:1901701 386 0.037
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.036
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.036
regulation of hydrolase activity GO:0051336 143 0.036
organophosphate metabolic process GO:0019637 370 0.036
carbohydrate derivative metabolic process GO:1901135 346 0.036
anatomical structure morphogenesis GO:0009653 298 0.036
regulation of calcium ion transport GO:0051924 77 0.035
chemical homeostasis GO:0048878 292 0.035
rna biosynthetic process GO:0032774 380 0.035
protein complex subunit organization GO:0071822 302 0.034
response to decreased oxygen levels GO:0036293 237 0.034
cellular response to endogenous stimulus GO:0071495 377 0.034
positive regulation of apoptotic process GO:0043065 154 0.034
negative regulation of cellular metabolic process GO:0031324 281 0.033
secretion by cell GO:0032940 248 0.032
protein phosphorylation GO:0006468 345 0.032
response to metal ion GO:0010038 253 0.031
cellular nitrogen compound catabolic process GO:0044270 163 0.031
wound healing GO:0042060 122 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.031
regulation of membrane potential GO:0042391 110 0.031
cellular ketone metabolic process GO:0042180 51 0.031
cellular lipid metabolic process GO:0044255 208 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.030
ion homeostasis GO:0050801 212 0.030
secretion GO:0046903 307 0.030
nucleic acid templated transcription GO:0097659 379 0.030
cell cell signaling GO:0007267 335 0.030
ribonucleotide metabolic process GO:0009259 231 0.030
organic acid biosynthetic process GO:0016053 83 0.029
calcium ion transport GO:0006816 131 0.029
regulation of intracellular signal transduction GO:1902531 218 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.029
cellular homeostasis GO:0019725 252 0.029
response to peptide hormone GO:0043434 278 0.028
nucleoside phosphate metabolic process GO:0006753 283 0.028
positive regulation of response to stimulus GO:0048584 285 0.027
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
negative regulation of programmed cell death GO:0043069 183 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.027
regulation of response to external stimulus GO:0032101 106 0.027
cellular chemical homeostasis GO:0055082 247 0.027
positive regulation of cell differentiation GO:0045597 217 0.027
oxoacid metabolic process GO:0043436 290 0.027
macromolecular complex assembly GO:0065003 273 0.027
cellular cation homeostasis GO:0030003 180 0.027
cellular metal ion homeostasis GO:0006875 172 0.026
positive regulation of ion transport GO:0043270 94 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
positive regulation of phosphorylation GO:0042327 177 0.026
negative regulation of cell differentiation GO:0045596 99 0.025
negative regulation of protein metabolic process GO:0051248 114 0.025
regulation of secretion GO:0051046 224 0.024
purine nucleoside catabolic process GO:0006152 124 0.024
cellular component assembly GO:0022607 360 0.024
glomerular mesangial cell proliferation GO:0072110 4 0.024
carboxylic acid biosynthetic process GO:0046394 83 0.023
regulation of cell differentiation GO:0045595 320 0.023
calcium ion homeostasis GO:0055074 162 0.023
positive regulation of phosphate metabolic process GO:0045937 262 0.022
regulation of neurogenesis GO:0050767 247 0.022
metal ion homeostasis GO:0055065 186 0.022
regulation of protein maturation GO:1903317 50 0.022
negative regulation of cellular protein metabolic process GO:0032269 106 0.022
protein processing GO:0016485 68 0.022
negative regulation of biosynthetic process GO:0009890 168 0.022
regulation of hormone levels GO:0010817 187 0.022
response to extracellular stimulus GO:0009991 380 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
ras protein signal transduction GO:0007265 29 0.021
regulation of cellular component organization GO:0051128 368 0.021
cellular divalent inorganic cation homeostasis GO:0072503 162 0.021
brain development GO:0007420 247 0.021
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
small molecule biosynthetic process GO:0044283 124 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
positive regulation of molecular function GO:0044093 230 0.020
organic substance catabolic process GO:1901575 316 0.020
protein heterooligomerization GO:0051291 89 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
regulation of anatomical structure morphogenesis GO:0022603 141 0.020
lipid biosynthetic process GO:0008610 128 0.020
protein oligomerization GO:0051259 191 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
cellular calcium ion homeostasis GO:0006874 160 0.020
regulation of cell development GO:0060284 263 0.020
regulation of metal ion transport GO:0010959 118 0.020
cation homeostasis GO:0055080 195 0.020
inorganic ion transmembrane transport GO:0098660 229 0.020
macromolecular complex subunit organization GO:0043933 339 0.020
negative regulation of multicellular organismal process GO:0051241 203 0.020
cytosolic calcium ion homeostasis GO:0051480 140 0.020
regeneration GO:0031099 163 0.019
cellular component biogenesis GO:0044085 368 0.019
epithelium development GO:0060429 96 0.019
muscle system process GO:0003012 115 0.019
fatty acid metabolic process GO:0006631 99 0.019
immune system process GO:0002376 204 0.019
heterocycle catabolic process GO:0046700 167 0.019
homeostatic process GO:0042592 331 0.019
regulation of nervous system development GO:0051960 264 0.019
action potential GO:0001508 54 0.019
response to zinc ion GO:0010043 39 0.019
divalent metal ion transport GO:0070838 132 0.019
regulation of protein processing GO:0070613 50 0.019
oxidation reduction process GO:0055114 304 0.019
protein homooligomerization GO:0051260 91 0.019
organonitrogen compound biosynthetic process GO:1901566 167 0.019
peptide transport GO:0015833 97 0.019
response to oxygen levels GO:0070482 265 0.019
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.018
positive regulation of glomerulus development GO:0090193 4 0.018
glycosyl compound catabolic process GO:1901658 126 0.018
regulation of cellular localization GO:0060341 263 0.018
negative regulation of molecular function GO:0044092 133 0.018
negative regulation of developmental process GO:0051093 125 0.018
head development GO:0060322 247 0.018
Rat
positive regulation of glomerular mesangial cell proliferation GO:0072126 4 0.018
negative regulation of protein processing GO:0010955 47 0.017
cellular amino acid biosynthetic process GO:0008652 32 0.017
negative regulation of rna metabolic process GO:0051253 123 0.017
catabolic process GO:0009056 351 0.017
aromatic compound catabolic process GO:0019439 168 0.017
cellular amine metabolic process GO:0044106 38 0.017
biological adhesion GO:0022610 110 0.017
vesicle mediated transport GO:0016192 181 0.017
response to ketone GO:1901654 182 0.017
response to nutrient levels GO:0031667 370 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
cardiovascular system development GO:0072358 134 0.017
cell projection organization GO:0030030 302 0.016
nucleotide catabolic process GO:0009166 139 0.016
positive regulation of signaling GO:0023056 270 0.016
transforming growth factor beta1 production GO:0032905 2 0.016
neurological system process GO:0050877 219 0.016
regulation of secretion by cell GO:1903530 208 0.016
positive regulation of nucleotide metabolic process GO:0045981 91 0.016
regulation of glomerulus development GO:0090192 4 0.016
regulation of neuron differentiation GO:0045664 208 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
negative regulation of protein maturation GO:1903318 47 0.016
response to peptide GO:1901652 292 0.016
amine metabolic process GO:0009308 38 0.016
amide transport GO:0042886 105 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
purine containing compound catabolic process GO:0072523 138 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
purine containing compound metabolic process GO:0072521 253 0.016
ribonucleoside triphosphate metabolic process GO:0009199 141 0.016
negative regulation of apoptotic process GO:0043066 181 0.015
regulation of ion transmembrane transport GO:0034765 121 0.015
potassium ion transport GO:0006813 97 0.015
cellular component movement GO:0006928 248 0.015
cell cycle GO:0007049 101 0.015
negative regulation of secretion GO:0051048 82 0.015
response to cytokine GO:0034097 215 0.015
regulation of synaptic transmission GO:0050804 141 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
positive regulation of gene expression GO:0010628 244 0.015
cell migration GO:0016477 197 0.015
regulation of transmembrane transport GO:0034762 122 0.015
single organism intracellular transport GO:1902582 166 0.015
defense response GO:0006952 194 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
locomotion GO:0040011 237 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.014
positive regulation of nervous system development GO:0051962 178 0.014
proteolysis GO:0006508 175 0.014
hormone secretion GO:0046879 115 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
regulation of neuron projection development GO:0010975 161 0.014
growth GO:0040007 165 0.014
Rat
response to monosaccharide GO:0034284 159 0.014
regulation of catabolic process GO:0009894 113 0.014
single organism reproductive process GO:0044702 297 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
reactive nitrogen species metabolic process GO:2001057 1 0.014
single organism organelle organization GO:1902589 180 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
neuronal action potential GO:0019228 35 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
positive regulation of cell proliferation involved in kidney development GO:1901724 4 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
negative regulation of neuron differentiation GO:0045665 62 0.013
monocarboxylic acid biosynthetic process GO:0072330 48 0.013
response to calcium ion GO:0051592 59 0.013
reproductive process GO:0022414 372 0.013
cell activation GO:0001775 97 0.013
response to corticosteroid GO:0031960 235 0.013
neuron differentiation GO:0030182 368 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
purine nucleoside triphosphate catabolic process GO:0009146 122 0.013
regulation of calcium ion transmembrane transport GO:1903169 18 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.013
skeletal muscle cell differentiation GO:0035914 2 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
peptide hormone secretion GO:0030072 84 0.013
response to carbohydrate GO:0009743 183 0.013
response to biotic stimulus GO:0009607 226 0.013
multicellular organismal signaling GO:0035637 44 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
calcium ion transmembrane transport GO:0070588 70 0.013
negative regulation of cell communication GO:0010648 158 0.013
cellular component morphogenesis GO:0032989 155 0.013
single organism catabolic process GO:0044712 283 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
intracellular transport GO:0046907 185 0.013
peptide secretion GO:0002790 86 0.013
ribonucleoside triphosphate catabolic process GO:0009203 122 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
cell cycle checkpoint GO:0000075 2 0.013
regulation of phosphorylation GO:0042325 248 0.012
regulation of transforming growth factor beta1 production GO:0032908 2 0.012
response to glucocorticoid GO:0051384 223 0.012
regulation of lipid metabolic process GO:0019216 68 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
regulation of transmembrane transporter activity GO:0022898 49 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
protein maturation GO:0051604 68 0.012
response to hypoxia GO:0001666 231 0.012
response to vitamin GO:0033273 131 0.012
anion transport GO:0006820 178 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
regulation of cytokine production GO:0001817 56 0.012
response to hexose GO:0009746 144 0.012
hormone transport GO:0009914 121 0.012
coagulation GO:0050817 28 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
cellular amino acid metabolic process GO:0006520 107 0.012
nucleoside metabolic process GO:0009116 179 0.012
anterior posterior pattern specification GO:0009952 1 0.012
ribose phosphate biosynthetic process GO:0046390 87 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
regulation of glomerular mesangial cell proliferation GO:0072124 4 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
signal release GO:0023061 145 0.011
negative regulation of cell death GO:0060548 229 0.011
response to glucose GO:0009749 136 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
neuron projection development GO:0031175 273 0.011
cellular response to molecule of bacterial origin GO:0071219 56 0.011
microtubule organizing center organization GO:0031023 1 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
developmental growth GO:0048589 100 0.011
positive regulation of immune system process GO:0002684 90 0.011
regulation of protein modification process GO:0031399 194 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
localization of cell GO:0051674 202 0.011
regulation of vasculature development GO:1901342 44 0.011
multicellular organismal reproductive process GO:0048609 233 0.011
cellular response to biotic stimulus GO:0071216 59 0.011
response to oxidative stress GO:0006979 186 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
cellular response to oxidative stress GO:0034599 76 0.011
negative regulation of transport GO:0051051 136 0.011
regulation of kidney development GO:0090183 15 0.011
multi organism reproductive process GO:0044703 262 0.011
regulation of homeostatic process GO:0032844 101 0.011
regulation of transferase activity GO:0051338 123 0.011
glial cell differentiation GO:0010001 65 0.011
Rat
response to lipopolysaccharide GO:0032496 191 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.010
synaptic transmission GO:0007268 235 0.010
regulation of locomotion GO:0040012 148 0.010
macromolecule localization GO:0033036 252 0.010
cellular response to hormone stimulus GO:0032870 247 0.010
response to estradiol GO:0032355 164 0.010
cellular response to organonitrogen compound GO:0071417 197 0.010
circulatory system development GO:0072359 134 0.010
gliogenesis GO:0042063 93 0.010
Rat
muscle structure development GO:0061061 87 0.010
positive regulation of nucleic acid templated transcription GO:1903508 197 0.010
anatomical structure formation involved in morphogenesis GO:0048646 83 0.010
epithelial cell differentiation GO:0030855 71 0.010
negative regulation of secretion by cell GO:1903531 72 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010

Tspan8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
disease of cellular proliferation DOID:14566 0 0.011
sensory system disease DOID:0050155 0 0.011