Rattus norvegicus

0 known processes

Plcl2

phospholipase C-like 2

Plcl2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 365 0.120
nucleobase containing small molecule metabolic process GO:0055086 316 0.071
transmembrane transport GO:0055085 412 0.055
cation transport GO:0006812 382 0.052
Rat
cation transmembrane transport GO:0098655 263 0.051
metal ion transport GO:0030001 289 0.050
Rat
oxoacid metabolic process GO:0043436 290 0.050
inorganic cation transmembrane transport GO:0098662 202 0.049
regulation of cellular component organization GO:0051128 368 0.048
carboxylic acid metabolic process GO:0019752 289 0.046
organophosphate metabolic process GO:0019637 370 0.045
Rat
synaptic transmission GO:0007268 235 0.045
transcription dna templated GO:0006351 377 0.045
organic acid metabolic process GO:0006082 292 0.045
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.043
positive regulation of multicellular organismal process GO:0051240 387 0.043
cellular response to oxygen containing compound GO:1901701 386 0.043
nucleotide metabolic process GO:0009117 279 0.043
protein oligomerization GO:0051259 191 0.043
transcription from rna polymerase ii promoter GO:0006366 252 0.042
purine containing compound metabolic process GO:0072521 253 0.041
regulation of nucleic acid templated transcription GO:1903506 380 0.041
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.041
response to extracellular stimulus GO:0009991 380 0.040
central nervous system development GO:0007417 311 0.040
rna biosynthetic process GO:0032774 380 0.040
organic substance catabolic process GO:1901575 316 0.040
Rat
nucleic acid templated transcription GO:0097659 379 0.040
positive regulation of gene expression GO:0010628 244 0.039
rna metabolic process GO:0016070 406 0.038
cellular catabolic process GO:0044248 295 0.038
Rat
protein complex subunit organization GO:0071822 302 0.036
cellular response to hormone stimulus GO:0032870 247 0.035
positive regulation of developmental process GO:0051094 283 0.035
regulation of transcription dna templated GO:0006355 374 0.034
ribonucleotide metabolic process GO:0009259 231 0.033
regulation of rna biosynthetic process GO:2001141 381 0.032
positive regulation of cell differentiation GO:0045597 217 0.032
cell cell signaling GO:0007267 335 0.032
positive regulation of transport GO:0051050 245 0.032
response to nutrient levels GO:0031667 370 0.032
nitrogen compound transport GO:0071705 229 0.032
inorganic ion transmembrane transport GO:0098660 229 0.031
carbohydrate derivative metabolic process GO:1901135 346 0.031
purine nucleotide metabolic process GO:0006163 229 0.031
nucleoside phosphate metabolic process GO:0006753 283 0.031
response to acid chemical GO:0001101 222 0.031
cellular response to lipid GO:0071396 201 0.031
single organism catabolic process GO:0044712 283 0.030
Rat
cellular ketone metabolic process GO:0042180 51 0.030
secretion GO:0046903 307 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.030
positive regulation of rna metabolic process GO:0051254 203 0.030
cellular component biogenesis GO:0044085 368 0.029
head development GO:0060322 247 0.029
protein phosphorylation GO:0006468 345 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.029
single organism biosynthetic process GO:0044711 342 0.029
cellular amino acid metabolic process GO:0006520 107 0.028
positive regulation of cellular biosynthetic process GO:0031328 295 0.028
positive regulation of rna biosynthetic process GO:1902680 197 0.028
cellular component assembly GO:0022607 360 0.028
purine nucleoside triphosphate catabolic process GO:0009146 122 0.028
organelle organization GO:0006996 266 0.028
regulation of ion transport GO:0043269 245 0.028
Rat
regulation of molecular function GO:0065009 398 0.027
macromolecular complex subunit organization GO:0043933 339 0.027
ribose phosphate metabolic process GO:0019693 235 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.027
positive regulation of transcription dna templated GO:0045893 197 0.027
neuron differentiation GO:0030182 368 0.026
negative regulation of metabolic process GO:0009892 331 0.026
organonitrogen compound catabolic process GO:1901565 179 0.026
growth GO:0040007 165 0.026
protein complex biogenesis GO:0070271 263 0.026
negative regulation of cellular metabolic process GO:0031324 281 0.026
cellular response to organic cyclic compound GO:0071407 202 0.026
regulation of system process GO:0044057 208 0.026
intracellular signal transduction GO:0035556 314 0.026
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.025
monovalent inorganic cation transport GO:0015672 172 0.025
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
cellular response to stress GO:0033554 269 0.025
regulation of apoptotic process GO:0042981 335 0.025
cellular response to organonitrogen compound GO:0071417 197 0.025
response to oxygen levels GO:0070482 265 0.025
positive regulation of molecular function GO:0044093 230 0.025
catabolic process GO:0009056 351 0.025
Rat
amine metabolic process GO:0009308 38 0.024
negative regulation of cellular biosynthetic process GO:0031327 161 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
macromolecular complex assembly GO:0065003 273 0.024
response to inorganic substance GO:0010035 377 0.024
response to corticosteroid GO:0031960 235 0.024
positive regulation of nucleic acid templated transcription GO:1903508 197 0.024
homeostatic process GO:0042592 331 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
cellular response to peptide hormone stimulus GO:0071375 120 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
multicellular organism growth GO:0035264 1 0.023
ribonucleotide catabolic process GO:0009261 136 0.023
neuron projection development GO:0031175 273 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
programmed cell death GO:0012501 392 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
regulation of phosphate metabolic process GO:0019220 349 0.023
cellular amine metabolic process GO:0044106 38 0.023
positive regulation of cellular component organization GO:0051130 200 0.022
aging GO:0007568 241 0.022
anion transport GO:0006820 178 0.022
heterocycle catabolic process GO:0046700 167 0.022
response to decreased oxygen levels GO:0036293 237 0.022
cellular response to nitrogen compound GO:1901699 210 0.022
response to hypoxia GO:0001666 231 0.022
cellular nitrogen compound catabolic process GO:0044270 163 0.022
response to peptide GO:1901652 292 0.022
Rat
brain development GO:0007420 247 0.021
cellular homeostasis GO:0019725 252 0.021
purine containing compound catabolic process GO:0072523 138 0.021
cellular response to endogenous stimulus GO:0071495 377 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
regulation of nervous system development GO:0051960 264 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
regulation of synaptic transmission GO:0050804 141 0.021
ion homeostasis GO:0050801 212 0.021
response to oxidative stress GO:0006979 186 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.020
regulation of cell differentiation GO:0045595 320 0.020
protein complex assembly GO:0006461 263 0.020
blood circulation GO:0008015 183 0.020
response to ketone GO:1901654 182 0.020
reproductive process GO:0022414 372 0.020
macromolecule localization GO:0033036 252 0.020
organic acid transport GO:0015849 116 0.020
regulation of phosphorus metabolic process GO:0051174 349 0.020
regulation of multicellular organismal development GO:2000026 376 0.020
ribonucleoside metabolic process GO:0009119 174 0.020
cyclic nucleotide metabolic process GO:0009187 80 0.020
multicellular organism reproduction GO:0032504 233 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
regulation of catalytic activity GO:0050790 304 0.019
nucleoside metabolic process GO:0009116 179 0.019
positive regulation of cell projection organization GO:0031346 111 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.019
regulation of synaptic plasticity GO:0048167 70 0.019
reproduction GO:0000003 245 0.019
neurological system process GO:0050877 219 0.019
Rat
cellular chemical homeostasis GO:0055082 247 0.019
regulation of vesicle mediated transport GO:0060627 81 0.019
cognition GO:0050890 92 0.019
Rat
regulation of programmed cell death GO:0043067 341 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.019
purine nucleoside metabolic process GO:0042278 169 0.018
chemical homeostasis GO:0048878 292 0.018
positive regulation of nervous system development GO:0051962 178 0.018
glycosyl compound metabolic process GO:1901657 182 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
regulation of cell projection organization GO:0031344 175 0.018
negative regulation of rna metabolic process GO:0051253 123 0.018
nucleoside phosphate biosynthetic process GO:1901293 102 0.018
regulation of signal transduction GO:0009966 318 0.017
intracellular transport GO:0046907 185 0.017
Rat
cell projection organization GO:0030030 302 0.017
cell growth GO:0016049 104 0.017
response to glucocorticoid GO:0051384 223 0.017
behavior GO:0007610 205 0.017
Rat
response to metal ion GO:0010038 253 0.017
response to nutrient GO:0007584 248 0.017
proteolysis GO:0006508 175 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
oxidation reduction process GO:0055114 304 0.017
single organism organelle organization GO:1902589 180 0.017
cation homeostasis GO:0055080 195 0.017
regulation of protein metabolic process GO:0051246 289 0.017
negative regulation of gene expression GO:0010629 199 0.017
locomotion GO:0040011 237 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
regulation of cellular localization GO:0060341 263 0.017
cellular lipid metabolic process GO:0044255 208 0.017
Rat
calcium ion transport GO:0006816 131 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
response to growth factor GO:0070848 189 0.016
circulatory system process GO:0003013 183 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
vesicle mediated transport GO:0016192 181 0.016
Rat
regulation of purine nucleotide metabolic process GO:1900542 115 0.016
response to peptide hormone GO:0043434 278 0.016
Rat
cellular response to peptide GO:1901653 133 0.016
regulation of hydrolase activity GO:0051336 143 0.016
regulation of rna metabolic process GO:0051252 391 0.016
organic anion transport GO:0015711 132 0.016
muscle system process GO:0003012 115 0.016
response to estrogen GO:0043627 232 0.016
regulation of transmembrane transport GO:0034762 122 0.016
sex differentiation GO:0007548 113 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
ribonucleoside triphosphate metabolic process GO:0009199 141 0.016
ras protein signal transduction GO:0007265 29 0.016
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
carboxylic acid transport GO:0046942 115 0.015
response to vitamin GO:0033273 131 0.015
development of primary sexual characteristics GO:0045137 107 0.015
response to ethanol GO:0045471 162 0.015
secretion by cell GO:0032940 248 0.015
cellular response to glucocorticoid stimulus GO:0071385 68 0.015
regulation of growth GO:0040008 105 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
Rat
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
eye morphogenesis GO:0048592 4 0.015
purine nucleoside catabolic process GO:0006152 124 0.015
regulation of cell growth GO:0001558 85 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
negative regulation of cell death GO:0060548 229 0.015
cellular cation homeostasis GO:0030003 180 0.015
regulation of anatomical structure size GO:0090066 135 0.015
neuron development GO:0048666 286 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
gonad development GO:0008406 104 0.014
reproductive system development GO:0061458 128 0.014
nucleoside triphosphate metabolic process GO:0009141 144 0.014
calcium ion transmembrane transport GO:0070588 70 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
sensory organ development GO:0007423 74 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
regulation of cellular protein metabolic process GO:0032268 267 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
nucleotide catabolic process GO:0009166 139 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
cell projection morphogenesis GO:0048858 123 0.013
response to bacterium GO:0009617 200 0.013
cellular response to alcohol GO:0097306 87 0.013
regulation of cell proliferation GO:0042127 359 0.013
regulation of calcium ion transport GO:0051924 77 0.013
developmental growth GO:0048589 100 0.013
positive regulation of cell development GO:0010720 176 0.013
response to amino acid GO:0043200 75 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
localization of cell GO:0051674 202 0.013
female gonad development GO:0008585 53 0.013
reproductive structure development GO:0048608 128 0.013
nucleotide biosynthetic process GO:0009165 98 0.013
calcium ion homeostasis GO:0055074 162 0.013
regulation of transferase activity GO:0051338 123 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
carbohydrate metabolic process GO:0005975 130 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
aromatic compound catabolic process GO:0019439 168 0.013
regulation of neurogenesis GO:0050767 247 0.013
response to temperature stimulus GO:0009266 94 0.013
development of primary female sexual characteristics GO:0046545 56 0.013
organophosphate catabolic process GO:0046434 148 0.013
Rat
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
single organism reproductive process GO:0044702 297 0.013
apoptotic process GO:0006915 381 0.013
cellular response to extracellular stimulus GO:0031668 73 0.013
response to toxic substance GO:0009636 133 0.013
regulation of cell development GO:0060284 263 0.013
response to carbohydrate GO:0009743 183 0.013
Rat
potassium ion transport GO:0006813 97 0.013
Rat
response to external biotic stimulus GO:0043207 221 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
regulation of hormone levels GO:0010817 187 0.012
response to cytokine GO:0034097 215 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
protein autophosphorylation GO:0046777 66 0.012
positive regulation of cell death GO:0010942 184 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
response to insulin GO:0032868 133 0.012
positive regulation of ion transport GO:0043270 94 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
actin filament based process GO:0030029 86 0.012
cellular response to steroid hormone stimulus GO:0071383 93 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
regulation of neuron projection development GO:0010975 161 0.012
regulation of phosphorylation GO:0042325 248 0.012
protein localization GO:0008104 191 0.012
response to wounding GO:0009611 254 0.012
nucleoside catabolic process GO:0009164 126 0.012
positive regulation of secretion GO:0051047 140 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
response to organophosphorus GO:0046683 102 0.012
metal ion homeostasis GO:0055065 186 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
response to hexose GO:0009746 144 0.012
multi organism reproductive process GO:0044703 262 0.012
ribonucleoside monophosphate metabolic process GO:0009161 88 0.012
response to alkaloid GO:0043279 132 0.012
cellular ion homeostasis GO:0006873 184 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
amino acid transport GO:0006865 70 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
regulation of blood circulation GO:1903522 110 0.011
actin cytoskeleton organization GO:0030036 73 0.011
negative regulation of molecular function GO:0044092 133 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
chemosensory behavior GO:0007635 2 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
response to camp GO:0051591 91 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
regulation of membrane potential GO:0042391 110 0.011
dephosphorylation GO:0016311 98 0.011
positive regulation of synaptic transmission GO:0050806 62 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
cytoplasmic transport GO:0016482 115 0.011
positive regulation of cell communication GO:0010647 271 0.011
rhythmic process GO:0048511 156 0.011
heart contraction GO:0060047 57 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
developmental process involved in reproduction GO:0003006 159 0.011
regulation of neuron differentiation GO:0045664 208 0.011
female sex differentiation GO:0046660 59 0.011
gamete generation GO:0007276 124 0.011
divalent metal ion transport GO:0070838 132 0.011
response to lipopolysaccharide GO:0032496 191 0.011
sexual reproduction GO:0019953 148 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
response to starvation GO:0042594 59 0.011
response to biotic stimulus GO:0009607 226 0.011
organic hydroxy compound transport GO:0015850 77 0.011
response to activity GO:0014823 73 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
response to monosaccharide GO:0034284 159 0.010
Rat
olfactory behavior GO:0042048 2 0.010
regulation of anatomical structure morphogenesis GO:0022603 141 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
monocarboxylic acid metabolic process GO:0032787 152 0.010
divalent inorganic cation transport GO:0072511 134 0.010
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.010
gastrulation GO:0007369 2 0.010
response to purine containing compound GO:0014074 126 0.010
negative regulation of cell communication GO:0010648 158 0.010
sensory perception GO:0007600 101 0.010
Rat
regulation of metal ion transport GO:0010959 118 0.010
Rat
anatomical structure morphogenesis GO:0009653 298 0.010
synaptic growth at neuromuscular junction GO:0051124 1 0.010
neuron projection morphogenesis GO:0048812 122 0.010
embryonic pattern specification GO:0009880 1 0.010
negative regulation of signaling GO:0023057 157 0.010
ribonucleotide biosynthetic process GO:0009260 85 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010
positive regulation of protein metabolic process GO:0051247 178 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.010
axis specification GO:0009798 4 0.010
cellular component movement GO:0006928 248 0.010

Plcl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.040
central nervous system disease DOID:331 0 0.016
sensory system disease DOID:0050155 0 0.015