Rattus norvegicus

27 known processes

Fbn1

fibrillin 1

Fbn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
collagen fibril organization GO:0030199 1 0.628
cellular response to fluoride GO:1902618 1 0.535
response to fluoride GO:1902617 3 0.391
cartilage development involved in endochondral bone morphogenesis GO:0060351 3 0.289
extracellular fibril organization GO:0043206 1 0.272
growth plate cartilage development GO:0003417 2 0.256
endochondral bone morphogenesis GO:0060350 7 0.246
cellular response to nicotine GO:0071316 7 0.163
aorta development GO:0035904 2 0.158
tissue development GO:0009888 252 0.152
tooth eruption GO:0044691 1 0.118
elastic fiber assembly GO:0048251 1 0.111
peptide cross linking GO:0018149 1 0.107
response to norepinephrine GO:0071873 5 0.105
extracellular matrix organization GO:0030198 13 0.104
bone morphogenesis GO:0060349 11 0.101
odontogenesis GO:0042476 32 0.093
macromolecular complex subunit organization GO:0043933 339 0.088
embryonic skeletal system development GO:0048706 3 0.082
locomotion GO:0040011 237 0.079
skeletal system development GO:0001501 41 0.079
regulation of multicellular organismal development GO:2000026 376 0.077
response to mechanical stimulus GO:0009612 134 0.075
bone development GO:0060348 25 0.070
renal system development GO:0072001 67 0.068
cell motility GO:0048870 202 0.068
cellular response to tumor necrosis factor GO:0071356 46 0.065
developmental growth involved in morphogenesis GO:0060560 33 0.065
response to ionizing radiation GO:0010212 59 0.064
eye morphogenesis GO:0048592 4 0.063
cellular response to lipid GO:0071396 201 0.060
extracellular structure organization GO:0043062 13 0.059
response to vitamin e GO:0033197 24 0.059
cell substrate adhesion GO:0031589 29 0.055
protein complex subunit organization GO:0071822 302 0.055
cellular response to vitamin e GO:0071306 3 0.053
response to wounding GO:0009611 254 0.052
response to epidermal growth factor GO:0070849 18 0.051
cellular response to peptide hormone stimulus GO:0071375 120 0.051
cellular response to thyroid hormone stimulus GO:0097067 5 0.050
vasculature development GO:0001944 70 0.050
cell adhesion GO:0007155 110 0.048
cellular response to acid chemical GO:0071229 75 0.046
response to fibroblast growth factor GO:0071774 29 0.045
rna biosynthetic process GO:0032774 380 0.044
nucleic acid templated transcription GO:0097659 379 0.044
reproduction GO:0000003 245 0.043
camera type eye morphogenesis GO:0048593 2 0.041
cellular response to epidermal growth factor stimulus GO:0071364 12 0.041
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.038
formation of primary germ layer GO:0001704 1 0.038
connective tissue development GO:0061448 33 0.037
response to nutrient levels GO:0031667 370 0.037
cartilage development GO:0051216 22 0.036
cardiovascular system development GO:0072358 134 0.035
gastrulation GO:0007369 2 0.035
anatomical structure morphogenesis GO:0009653 298 0.035
cellular response to organic cyclic compound GO:0071407 202 0.035
protein heterotrimerization GO:0070208 2 0.035
regulation of transcription dna templated GO:0006355 374 0.034
positive regulation of cell communication GO:0010647 271 0.033
cellular response to growth factor stimulus GO:0071363 162 0.033
wound healing spreading of cells GO:0044319 2 0.032
regulation of cell development GO:0060284 263 0.032
cellular response to oxygen containing compound GO:1901701 386 0.032
response to tumor necrosis factor GO:0034612 56 0.031
regulation of rna biosynthetic process GO:2001141 381 0.031
transcription dna templated GO:0006351 377 0.031
chondrocyte differentiation GO:0002062 10 0.031
response to corticosteroid GO:0031960 235 0.031
response to extracellular stimulus GO:0009991 380 0.030
ras protein signal transduction GO:0007265 29 0.030
cellular response to extracellular stimulus GO:0031668 73 0.030
positive regulation of stem cell differentiation GO:2000738 2 0.030
wound healing GO:0042060 122 0.029
positive regulation of cell differentiation GO:0045597 217 0.029
response to catecholamine GO:0071869 16 0.028
reproductive process GO:0022414 372 0.027
cellular response to peptide GO:1901653 133 0.027
response to oxidative stress GO:0006979 186 0.026
eye development GO:0001654 50 0.026
response to hyperoxia GO:0055093 45 0.025
regulation of neuron death GO:1901214 115 0.025
regulation of cellular component organization GO:0051128 368 0.025
response to amino acid GO:0043200 75 0.024
response to nutrient GO:0007584 248 0.024
rna metabolic process GO:0016070 406 0.024
skin morphogenesis GO:0043589 2 0.024
regulation of neurogenesis GO:0050767 247 0.024
ossification GO:0001503 70 0.024
positive regulation of transcription dna templated GO:0045893 197 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
skeletal system morphogenesis GO:0048705 12 0.023
regulation of ossification GO:0030278 32 0.023
cellular response to retinoic acid GO:0071300 27 0.023
cellular component biogenesis GO:0044085 368 0.022
response to monoamine GO:0071867 17 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.022
anatomical structure formation involved in morphogenesis GO:0048646 83 0.022
negative regulation of cell differentiation GO:0045596 99 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
artery development GO:0060840 3 0.021
regulation of nucleic acid templated transcription GO:1903506 380 0.021
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.020
positive regulation of rna metabolic process GO:0051254 203 0.020
response to cytokine GO:0034097 215 0.020
cellular response to endogenous stimulus GO:0071495 377 0.020
aging GO:0007568 241 0.020
neuron apoptotic process GO:0051402 88 0.020
cellular response to nitrogen compound GO:1901699 210 0.019
response to vitamin GO:0033273 131 0.019
lipid biosynthetic process GO:0008610 128 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
enzyme linked receptor protein signaling pathway GO:0007167 116 0.019
organ morphogenesis GO:0009887 75 0.019
response to biotic stimulus GO:0009607 226 0.019
blood vessel morphogenesis GO:0048514 58 0.019
single organism biosynthetic process GO:0044711 342 0.018
regulation of nervous system development GO:0051960 264 0.018
neuron projection development GO:0031175 273 0.018
positive regulation of signaling GO:0023056 270 0.018
response to inorganic substance GO:0010035 377 0.018
regulation of embryonic development GO:0045995 2 0.018
cellular response to alkaloid GO:0071312 25 0.018
response to nicotine GO:0035094 51 0.017
response to reactive oxygen species GO:0000302 120 0.017
regulation of rna metabolic process GO:0051252 391 0.017
positive regulation of response to stimulus GO:0048584 285 0.017
blood vessel development GO:0001568 69 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
cellular response to nutrient levels GO:0031669 60 0.016
regulation of epithelial to mesenchymal transition GO:0010717 2 0.016
single organism reproductive process GO:0044702 297 0.016
negative regulation of developmental process GO:0051093 125 0.016
organelle organization GO:0006996 266 0.016
response to growth factor GO:0070848 189 0.016
rho protein signal transduction GO:0007266 11 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
regulation of signal transduction GO:0009966 318 0.016
response to peptide hormone GO:0043434 278 0.016
growth GO:0040007 165 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.015
biomineral tissue development GO:0031214 12 0.015
neuron development GO:0048666 286 0.015
multicellular organism reproduction GO:0032504 233 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
gamete generation GO:0007276 124 0.015
regulation of cell projection organization GO:0031344 175 0.014
muscle structure development GO:0061061 87 0.014
sensory perception of light stimulus GO:0050953 3 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
cellular response to abiotic stimulus GO:0071214 85 0.014
salivary gland development GO:0007431 3 0.014
cellular amine metabolic process GO:0044106 38 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
multi organism reproductive process GO:0044703 262 0.014
response to thyroid hormone GO:0097066 17 0.014
cellular response to nutrient GO:0031670 30 0.014
cellular response to fibroblast growth factor stimulus GO:0044344 24 0.014
cell projection organization GO:0030030 302 0.014
organic acid metabolic process GO:0006082 292 0.014
negative regulation of gene expression GO:0010629 199 0.014
cellular ketone metabolic process GO:0042180 51 0.013
response to bacterium GO:0009617 200 0.013
positive regulation of developmental process GO:0051094 283 0.013
visual perception GO:0007601 3 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
regulation of stem cell differentiation GO:2000736 2 0.013
cell morphogenesis GO:0000902 142 0.013
macromolecular complex assembly GO:0065003 273 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
apoptotic process GO:0006915 381 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
protein complex biogenesis GO:0070271 263 0.013
neuron migration GO:0001764 21 0.013
positive regulation of bone mineralization GO:0030501 4 0.012
protein heterooligomerization GO:0051291 89 0.012
muscle organ development GO:0007517 50 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
dendrite development GO:0016358 72 0.012
regulation of neuron projection development GO:0010975 161 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
protein complex assembly GO:0006461 263 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
response to alkaloid GO:0043279 132 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
intracellular signal transduction GO:0035556 314 0.012
urogenital system development GO:0001655 78 0.012
response to x ray GO:0010165 15 0.012
cellular component movement GO:0006928 248 0.012
response to increased oxygen levels GO:0036296 45 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
regulation of cell differentiation GO:0045595 320 0.011
circulatory system development GO:0072359 134 0.011
anterior posterior pattern specification GO:0009952 1 0.011
negative regulation of metabolic process GO:0009892 331 0.011
response to estradiol GO:0032355 164 0.011
actin filament based movement GO:0030048 16 0.011
regulation of neuron differentiation GO:0045664 208 0.011
response to radiation GO:0009314 137 0.011
digestive tract development GO:0048565 39 0.011
development of primary sexual characteristics GO:0045137 107 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.011
biological adhesion GO:0022610 110 0.011
muscle tissue morphogenesis GO:0060415 1 0.010
axonogenesis GO:0007409 71 0.010
striated muscle tissue development GO:0014706 58 0.010
response to estrogen GO:0043627 232 0.010
central nervous system development GO:0007417 311 0.010
positive regulation of gene expression GO:0010628 244 0.010
embryonic pattern specification GO:0009880 1 0.010

Fbn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.456
musculoskeletal system disease DOID:17 0 0.456
collagen disease DOID:854 0 0.377
ehlers danlos syndrome DOID:13359 0 0.377
connective tissue disease DOID:65 0 0.377
osteochondrodysplasia DOID:2256 0 0.313
osteogenesis imperfecta DOID:12347 0 0.313
bone development disease DOID:0080006 0 0.313
bone disease DOID:0080001 0 0.313
retinal disease DOID:5679 0 0.017
retinal degeneration DOID:8466 0 0.017
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.017
nervous system disease DOID:863 0 0.017
eye disease DOID:5614 0 0.017