Rattus norvegicus

51 known processes

Pde4b

phosphodiesterase 4B, cAMP specific

(Aliases: MGC93193,Pde4B2,Pde4B1,PDE4/IVb,Pde4B4,Pde4B3)

Pde4b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
anatomical structure morphogenesis GO:0009653 298 0.466
Fly
positive regulation of cell migration GO:0030335 96 0.417
cell projection organization GO:0030030 302 0.347
Fly
neuron development GO:0048666 286 0.315
Fly
localization of cell GO:0051674 202 0.301
apoptotic process GO:0006915 381 0.300
regulation of intracellular signal transduction GO:1902531 218 0.286
Fly
intracellular signal transduction GO:0035556 314 0.285
Rat Fly
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.284
rna metabolic process GO:0016070 406 0.272
neuron projection development GO:0031175 273 0.267
Fly
enzyme linked receptor protein signaling pathway GO:0007167 116 0.253
negative regulation of biosynthetic process GO:0009890 168 0.251
locomotion GO:0040011 237 0.250
positive regulation of cell motility GO:2000147 97 0.249
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.244
positive regulation of cellular component movement GO:0051272 102 0.239
positive regulation of locomotion GO:0040017 102 0.235
regulation of apoptotic process GO:0042981 335 0.233
negative regulation of nucleic acid templated transcription GO:1903507 117 0.231
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.229
regulation of nucleic acid templated transcription GO:1903506 380 0.223
cellular component morphogenesis GO:0032989 155 0.223
Fly
cell motility GO:0048870 202 0.222
cell migration GO:0016477 197 0.219
neurological system process GO:0050877 219 0.216
Rat Fly
regulation of programmed cell death GO:0043067 341 0.214
cellular component movement GO:0006928 248 0.214
regulation of rna biosynthetic process GO:2001141 381 0.209
regulation of cell migration GO:0030334 128 0.204
regulation of transcription dna templated GO:0006355 374 0.198
oxoacid metabolic process GO:0043436 290 0.194
regulation of rna metabolic process GO:0051252 391 0.191
behavior GO:0007610 205 0.189
Fly
regulation of cellular component movement GO:0051270 150 0.189
nucleic acid templated transcription GO:0097659 379 0.189
regulation of signal transduction GO:0009966 318 0.188
Fly
regulation of cellular component organization GO:0051128 368 0.185
transcription from rna polymerase ii promoter GO:0006366 252 0.184
single organism behavior GO:0044708 130 0.183
Fly
negative regulation of rna metabolic process GO:0051253 123 0.179
regulation of cell differentiation GO:0045595 320 0.175
rna biosynthetic process GO:0032774 380 0.174
carboxylic acid metabolic process GO:0019752 289 0.174
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.167
regulation of phosphate metabolic process GO:0019220 349 0.165
cellular component assembly GO:0022607 360 0.165
dendrite morphogenesis GO:0048813 43 0.164
cellular component biogenesis GO:0044085 368 0.163
protein phosphorylation GO:0006468 345 0.163
cell morphogenesis involved in differentiation GO:0000904 119 0.163
Fly
central nervous system development GO:0007417 311 0.156
negative regulation of gene expression GO:0010629 199 0.153
regulation of cell proliferation GO:0042127 359 0.152
single organism reproductive process GO:0044702 297 0.152
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.151
negative regulation of macromolecule metabolic process GO:0010605 260 0.151
programmed cell death GO:0012501 392 0.150
positive regulation of gene expression GO:0010628 244 0.146
transcription dna templated GO:0006351 377 0.146
regulation of locomotion GO:0040012 148 0.145
neuron projection morphogenesis GO:0048812 122 0.142
Fly
positive regulation of multicellular organismal process GO:0051240 387 0.142
Human
negative regulation of signaling GO:0023057 157 0.141
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.140
cell projection morphogenesis GO:0048858 123 0.137
Fly
regulation of nervous system development GO:0051960 264 0.135
organelle organization GO:0006996 266 0.132
reproductive process GO:0022414 372 0.132
cell morphogenesis GO:0000902 142 0.131
Fly
response to peptide GO:1901652 292 0.129
positive regulation of biosynthetic process GO:0009891 319 0.129
cell part morphogenesis GO:0032990 123 0.125
Fly
neuron differentiation GO:0030182 368 0.123
Fly
learning or memory GO:0007611 90 0.119
Fly
blood circulation GO:0008015 183 0.119
organic acid metabolic process GO:0006082 292 0.118
regulation of cellular protein metabolic process GO:0032268 267 0.117
response to wounding GO:0009611 254 0.115
positive regulation of cell communication GO:0010647 271 0.114
regulation of multicellular organismal development GO:2000026 376 0.113
response to estradiol GO:0032355 164 0.112
positive regulation of phosphate metabolic process GO:0045937 262 0.111
cellular response to oxygen containing compound GO:1901701 386 0.109
regulation of protein modification process GO:0031399 194 0.107
regulation of molecular function GO:0065009 398 0.107
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.106
protein complex subunit organization GO:0071822 302 0.105
negative regulation of transcription dna templated GO:0045892 116 0.105
regulation of protein metabolic process GO:0051246 289 0.105
negative regulation of cellular biosynthetic process GO:0031327 161 0.104
macromolecular complex subunit organization GO:0043933 339 0.101
regulation of response to external stimulus GO:0032101 106 0.101
regulation of cell development GO:0060284 263 0.100
positive regulation of developmental process GO:0051094 283 0.098
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.097
Fly
circulatory system development GO:0072359 134 0.097
negative regulation of cellular metabolic process GO:0031324 281 0.095
positive regulation of cellular component organization GO:0051130 200 0.094
negative regulation of rna biosynthetic process GO:1902679 118 0.094
negative regulation of metabolic process GO:0009892 331 0.092
regulation of cell motility GO:2000145 131 0.092
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.092
single organism biosynthetic process GO:0044711 342 0.091
macromolecular complex assembly GO:0065003 273 0.090
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.090
regulation of phosphorylation GO:0042325 248 0.088
positive regulation of cellular biosynthetic process GO:0031328 295 0.088
response to decreased oxygen levels GO:0036293 237 0.088
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.088
biological adhesion GO:0022610 110 0.088
cellular response to nitrogen compound GO:1901699 210 0.085
regulation of system process GO:0044057 208 0.084
macromolecule localization GO:0033036 252 0.083
regulation of protein phosphorylation GO:0001932 183 0.083
positive regulation of transcription dna templated GO:0045893 197 0.083
reproduction GO:0000003 245 0.083
taxis GO:0042330 67 0.082
positive regulation of cell proliferation GO:0008284 249 0.082
signal transduction by phosphorylation GO:0023014 144 0.082
cognition GO:0050890 92 0.080
Fly
cell cell signaling GO:0007267 335 0.079
Rat Fly
cellular amino acid metabolic process GO:0006520 107 0.078
response to glucocorticoid GO:0051384 223 0.077
circulatory system process GO:0003013 183 0.076
regulation of mapk cascade GO:0043408 116 0.076
response to estrogen GO:0043627 232 0.075
regulation of neurogenesis GO:0050767 247 0.075
cellular response to cytokine stimulus GO:0071345 127 0.075
response to light stimulus GO:0009416 52 0.073
positive regulation of intracellular signal transduction GO:1902533 138 0.071
positive regulation of rna biosynthetic process GO:1902680 197 0.071
regulation of neuron differentiation GO:0045664 208 0.071
dendrite development GO:0016358 72 0.071
positive regulation of cell differentiation GO:0045597 217 0.071
positive regulation of nervous system development GO:0051962 178 0.070
response to biotic stimulus GO:0009607 226 0.069
negative regulation of cell death GO:0060548 229 0.069
axon development GO:0061564 96 0.069
Fly
regulation of phosphorus metabolic process GO:0051174 349 0.069
response to radiation GO:0009314 137 0.068
response to corticosteroid GO:0031960 235 0.068
regulation of response to stress GO:0080134 126 0.068
positive regulation of signaling GO:0023056 270 0.068
negative regulation of programmed cell death GO:0043069 183 0.067
cellular ketone metabolic process GO:0042180 51 0.067
protein complex assembly GO:0006461 263 0.067
cellular homeostasis GO:0019725 252 0.067
tissue morphogenesis GO:0048729 22 0.066
cation transport GO:0006812 382 0.066
rhythmic process GO:0048511 156 0.065
mapk cascade GO:0000165 140 0.065
cellular amine metabolic process GO:0044106 38 0.065
neuron death GO:0070997 127 0.064
cellular response to organonitrogen compound GO:0071417 197 0.064
negative regulation of apoptotic process GO:0043066 181 0.064
positive regulation of protein modification process GO:0031401 142 0.063
growth GO:0040007 165 0.063
Fly
carbohydrate derivative metabolic process GO:1901135 346 0.063
positive regulation of signal transduction GO:0009967 175 0.063
response to hypoxia GO:0001666 231 0.062
regulation of cellular amino acid metabolic process GO:0006521 2 0.062
regulation of cellular ketone metabolic process GO:0010565 27 0.062
organophosphate metabolic process GO:0019637 370 0.062
response to lipopolysaccharide GO:0032496 191 0.061
tube development GO:0035295 89 0.061
multicellular organismal reproductive process GO:0048609 233 0.060
gastrulation GO:0007369 2 0.060
multicellular organism reproduction GO:0032504 233 0.059
positive regulation of neurogenesis GO:0050769 165 0.059
organic substance catabolic process GO:1901575 316 0.059
protein localization GO:0008104 191 0.058
brain development GO:0007420 247 0.058
regulation of map kinase activity GO:0043405 53 0.058
response to cytokine GO:0034097 215 0.058
negative regulation of multicellular organismal process GO:0051241 203 0.057
response to other organism GO:0051707 220 0.057
negative regulation of developmental process GO:0051093 125 0.057
protein complex biogenesis GO:0070271 263 0.056
epithelium development GO:0060429 96 0.056
metal ion homeostasis GO:0055065 186 0.055
regulation of cell adhesion GO:0030155 52 0.055
cellular response to hormone stimulus GO:0032870 247 0.055
kidney development GO:0001822 67 0.055
purine containing compound metabolic process GO:0072521 253 0.055
cellular response to stress GO:0033554 269 0.054
organonitrogen compound biosynthetic process GO:1901566 167 0.054
regulation of protein kinase activity GO:0045859 105 0.054
response to oxygen levels GO:0070482 265 0.054
positive regulation of cellular protein metabolic process GO:0032270 167 0.053
wound healing GO:0042060 122 0.052
secretion GO:0046903 307 0.052
Rat
olfactory learning GO:0008355 1 0.052
positive regulation of protein phosphorylation GO:0001934 135 0.052
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.052
multi organism reproductive process GO:0044703 262 0.051
homeostatic process GO:0042592 331 0.051
positive regulation of response to stimulus GO:0048584 285 0.051
Human
head development GO:0060322 247 0.051
single organism organelle organization GO:1902589 180 0.051
intracellular transport GO:0046907 185 0.050
positive regulation of mapk cascade GO:0043410 92 0.050
multi multicellular organism process GO:0044706 138 0.050
urogenital system development GO:0001655 78 0.050
response to camp GO:0051591 91 0.049
chemotaxis GO:0006935 66 0.049
regulation of cellular amine metabolic process GO:0033238 8 0.049
positive regulation of catalytic activity GO:0043085 184 0.049
amine metabolic process GO:0009308 38 0.048
erk1 and erk2 cascade GO:0070371 48 0.048
cell type specific apoptotic process GO:0097285 134 0.048
cell adhesion GO:0007155 110 0.048
response to insulin GO:0032868 133 0.048
muscle contraction GO:0006936 88 0.047
cellular protein localization GO:0034613 122 0.047
regulation of immune system process GO:0002682 123 0.047
Human
response to bacterium GO:0009617 200 0.047
positive regulation of phosphorylation GO:0042327 177 0.047
cellular response to lipid GO:0071396 201 0.047
positive regulation of nucleic acid templated transcription GO:1903508 197 0.046
regulation of kinase activity GO:0043549 117 0.046
regulation of cell projection organization GO:0031344 175 0.046
positive regulation of rna metabolic process GO:0051254 203 0.046
neuron apoptotic process GO:0051402 88 0.046
developmental process involved in reproduction GO:0003006 159 0.046
response to peptide hormone GO:0043434 278 0.046
positive regulation of protein metabolic process GO:0051247 178 0.045
positive regulation of response to external stimulus GO:0032103 51 0.045
cellular divalent inorganic cation homeostasis GO:0072503 162 0.045
negative regulation of cell proliferation GO:0008285 119 0.045
renal system development GO:0072001 67 0.044
regulation of neuron death GO:1901214 115 0.044
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.044
hormone transport GO:0009914 121 0.044
Rat
regulation of establishment of planar polarity GO:0090175 2 0.043
circadian rhythm GO:0007623 88 0.043
cellular response to endogenous stimulus GO:0071495 377 0.043
nitrogen compound transport GO:0071705 229 0.043
Rat
regulation of neuron apoptotic process GO:0043523 83 0.043
positive regulation of neuron projection development GO:0010976 99 0.043
anatomical structure formation involved in morphogenesis GO:0048646 83 0.042
lipid metabolic process GO:0006629 283 0.042
defense response GO:0006952 194 0.042
cellular response to growth factor stimulus GO:0071363 162 0.042
single organism cell adhesion GO:0098602 46 0.042
regulation of organelle organization GO:0033043 80 0.042
positive regulation of phosphorus metabolic process GO:0010562 262 0.041
response to nutrient GO:0007584 248 0.041
regulation of homeostatic process GO:0032844 101 0.040
cardiovascular system development GO:0072358 134 0.040
digestive system development GO:0055123 41 0.040
regulation of anatomical structure morphogenesis GO:0022603 141 0.040
cellular chemical homeostasis GO:0055082 247 0.040
regulation of cytoskeleton organization GO:0051493 49 0.040
tissue development GO:0009888 252 0.039
positive regulation of cell development GO:0010720 176 0.039
cell cell junction organization GO:0045216 20 0.039
cyclic nucleotide metabolic process GO:0009187 80 0.038
vasculature development GO:0001944 70 0.038
protein transport GO:0015031 132 0.038
regulation of cell cycle GO:0051726 73 0.038
regulation of transferase activity GO:0051338 123 0.037
negative regulation of response to stimulus GO:0048585 155 0.036
negative regulation of cell differentiation GO:0045596 99 0.036
positive regulation of focal adhesion assembly GO:0051894 2 0.036
calcium ion homeostasis GO:0055074 162 0.036
monovalent inorganic cation transport GO:0015672 172 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.036
response to oxidative stress GO:0006979 186 0.036
cellular macromolecule localization GO:0070727 122 0.035
mitotic spindle organization GO:0007052 2 0.035
negative regulation of neuron apoptotic process GO:0043524 45 0.035
ion homeostasis GO:0050801 212 0.035
response to acid chemical GO:0001101 222 0.035
reproductive system development GO:0061458 128 0.034
transforming growth factor beta3 production GO:0032907 2 0.034
regulation of proteasomal protein catabolic process GO:0061136 4 0.033
cytokine production GO:0001816 61 0.033
Human
digestive tract development GO:0048565 39 0.033
cell cycle GO:0007049 101 0.033
catabolic process GO:0009056 351 0.033
aging GO:0007568 241 0.033
response to growth factor GO:0070848 189 0.033
inflammatory response GO:0006954 150 0.033
regulation of anatomical structure size GO:0090066 135 0.033
chemical homeostasis GO:0048878 292 0.033
regulation of catalytic activity GO:0050790 304 0.033
positive regulation of cellular amine metabolic process GO:0033240 3 0.032
cellular response to peptide GO:1901653 133 0.032
reactive oxygen species metabolic process GO:0072593 37 0.032
ameboidal type cell migration GO:0001667 26 0.032
reproductive structure development GO:0048608 128 0.032
regulation of smooth muscle cell migration GO:0014910 36 0.032
regeneration GO:0031099 163 0.032
actin filament based process GO:0030029 86 0.032
axis specification GO:0009798 4 0.032
cellular cation homeostasis GO:0030003 180 0.032
regulation of growth GO:0040008 105 0.032
regulation of cell morphogenesis GO:0022604 77 0.032
positive regulation of immune system process GO:0002684 90 0.031
Human
response to transforming growth factor beta GO:0071559 46 0.031
regulation of neuron projection development GO:0010975 161 0.031
single organism catabolic process GO:0044712 283 0.031
response to purine containing compound GO:0014074 126 0.031
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.031
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.031
peptidyl amino acid modification GO:0018193 126 0.031
cell junction organization GO:0034330 21 0.030
neural crest cell differentiation GO:0014033 2 0.030
regulation of canonical wnt signaling pathway GO:0060828 4 0.030
response to mechanical stimulus GO:0009612 134 0.030
negative regulation of signal transduction GO:0009968 83 0.030
positive regulation of cell death GO:0010942 184 0.030
negative regulation of neuron death GO:1901215 69 0.030
blood vessel morphogenesis GO:0048514 58 0.029
cellular response to lipopolysaccharide GO:0071222 55 0.029
single organism intracellular transport GO:1902582 166 0.029
regulation of hormone secretion GO:0046883 106 0.029
Rat
peptidyl tyrosine phosphorylation GO:0018108 72 0.029
cellular response to organic cyclic compound GO:0071407 202 0.029
purine ribonucleotide metabolic process GO:0009150 227 0.029
tube formation GO:0035148 3 0.029
cellular response to molecule of bacterial origin GO:0071219 56 0.028
vascular process in circulatory system GO:0003018 96 0.028
angiogenesis GO:0001525 53 0.028
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.028
regulation of nucleotide metabolic process GO:0006140 117 0.028
gamete generation GO:0007276 124 0.027
single organism cellular localization GO:1902580 102 0.027
anterior posterior pattern specification GO:0009952 1 0.027
response to ketone GO:1901654 182 0.027
response to external biotic stimulus GO:0043207 221 0.027
negative regulation of cellular component organization GO:0051129 83 0.027
dna metabolic process GO:0006259 96 0.027
learning GO:0007612 33 0.027
Fly
organ morphogenesis GO:0009887 75 0.026
cellular ion homeostasis GO:0006873 184 0.026
regulation of body fluid levels GO:0050878 90 0.026
gland development GO:0048732 155 0.026
non canonical wnt signaling pathway GO:0035567 3 0.026
synaptic transmission GO:0007268 235 0.026
Fly
vesicle mediated transport GO:0016192 181 0.026
embryonic pattern specification GO:0009880 1 0.026
response to organophosphorus GO:0046683 102 0.026
cellular calcium ion homeostasis GO:0006874 160 0.026
inorganic ion transmembrane transport GO:0098660 229 0.026
negative regulation of neuron differentiation GO:0045665 62 0.026
positive regulation of transport GO:0051050 245 0.026
cellular response to insulin stimulus GO:0032869 81 0.025
spindle organization GO:0007051 2 0.025
response to glucose GO:0009749 136 0.025
synaptic growth at neuromuscular junction GO:0051124 1 0.025
positive regulation of map kinase activity GO:0043406 46 0.025
actin cytoskeleton organization GO:0030036 73 0.025
cellular response to peptide hormone stimulus GO:0071375 120 0.025
response to carbohydrate GO:0009743 183 0.025
regulation of cellular localization GO:0060341 263 0.025
Rat
t cell activation GO:0042110 29 0.024
cellular catabolic process GO:0044248 295 0.024
positive regulation of hydrolase activity GO:0051345 86 0.024
positive regulation of programmed cell death GO:0043068 157 0.024
retina morphogenesis in camera type eye GO:0060042 1 0.024
anion transport GO:0006820 178 0.024
response to inorganic substance GO:0010035 377 0.024
Rat
cellular metal ion homeostasis GO:0006875 172 0.024
regulation of metal ion transport GO:0010959 118 0.023
neural crest cell development GO:0014032 2 0.023
multicellular organism growth GO:0035264 1 0.023
cytoskeleton organization GO:0007010 111 0.023
positive regulation of cellular component biogenesis GO:0044089 55 0.023
gliogenesis GO:0042063 93 0.023
erythrocyte differentiation GO:0030218 1 0.023
cellular response to alcohol GO:0097306 87 0.023
negative regulation of cell communication GO:0010648 158 0.023
Rat
immune system process GO:0002376 204 0.023
Human
positive regulation of protein kinase activity GO:0045860 73 0.023
regulation of purine nucleotide metabolic process GO:1900542 115 0.023
ras protein signal transduction GO:0007265 29 0.023
regulation of defense response GO:0031347 68 0.023
reactive oxygen species biosynthetic process GO:1903409 8 0.023
intracellular receptor signaling pathway GO:0030522 35 0.023
response to nutrient levels GO:0031667 370 0.023
neuromuscular process GO:0050905 2 0.023
cellular response to biotic stimulus GO:0071216 59 0.022
positive regulation of transferase activity GO:0051347 81 0.022
cation homeostasis GO:0055080 195 0.022
response to extracellular stimulus GO:0009991 380 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
positive regulation of cell adhesion GO:0045785 30 0.022
response to vitamin GO:0033273 131 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.021
vascular endothelial growth factor receptor signaling pathway GO:0048010 8 0.021
sexual reproduction GO:0019953 148 0.021
cellular response to oxidative stress GO:0034599 76 0.021
positive regulation of defense response GO:0031349 37 0.021
immune response GO:0006955 104 0.021
Human
carbohydrate derivative biosynthetic process GO:1901137 124 0.021
regulation of ossification GO:0030278 32 0.021
response to reactive oxygen species GO:0000302 120 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
hormone secretion GO:0046879 115 0.021
Rat
neuron neuron synaptic transmission GO:0007270 60 0.021
eye morphogenesis GO:0048592 4 0.021
calcium ion transport GO:0006816 131 0.021
membrane organization GO:0061024 94 0.021
muscle cell proliferation GO:0033002 84 0.020
positive regulation of endothelial cell migration GO:0010595 4 0.020
peptidyl tyrosine modification GO:0018212 72 0.020
regulation of protein serine threonine kinase activity GO:0071900 64 0.020
protein maturation GO:0051604 68 0.020
associative learning GO:0008306 19 0.020
Fly
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.020
neural crest cell migration GO:0001755 1 0.020
negative regulation of osteoblast differentiation GO:0045668 2 0.020
nucleotide metabolic process GO:0009117 279 0.020
cellular response to steroid hormone stimulus GO:0071383 93 0.020
regulation of cell substrate adhesion GO:0010810 18 0.020
negative regulation of protein metabolic process GO:0051248 114 0.020
negative regulation of nervous system development GO:0051961 79 0.020
mesoderm development GO:0007498 2 0.020
positive regulation of cell projection organization GO:0031346 111 0.020
small molecule biosynthetic process GO:0044283 124 0.020
proteolysis GO:0006508 175 0.020
secretion by cell GO:0032940 248 0.020
Rat
regulation of smooth muscle cell proliferation GO:0048660 75 0.020
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.020
signal release GO:0023061 145 0.020
Rat
nucleotide catabolic process GO:0009166 139 0.019
regulation of reactive oxygen species metabolic process GO:2000377 26 0.019
negative regulation of cellular protein metabolic process GO:0032269 106 0.019
olfactory behavior GO:0042048 2 0.019
regulation of peptide secretion GO:0002791 82 0.019
Rat
regulation of hydrolase activity GO:0051336 143 0.019
endocytosis GO:0006897 84 0.019
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.019
positive regulation of transforming growth factor beta3 production GO:0032916 2 0.019
positive regulation of apoptotic process GO:0043065 154 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
regulation of membrane potential GO:0042391 110 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
cell matrix adhesion GO:0007160 19 0.019
smooth muscle cell proliferation GO:0048659 77 0.019
chemosensory behavior GO:0007635 2 0.019
cell substrate adhesion GO:0031589 29 0.019
sensory perception GO:0007600 101 0.019
Rat
epithelial cell differentiation GO:0030855 71 0.019
regulation of synaptic transmission GO:0050804 141 0.019
reactive nitrogen species metabolic process GO:2001057 1 0.019
maintenance of location GO:0051235 17 0.019
response to molecule of bacterial origin GO:0002237 194 0.019
camera type eye morphogenesis GO:0048593 2 0.018
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.018
cardiac conduction GO:0061337 2 0.018
regulation of response to wounding GO:1903034 69 0.018
regulation of dendrite development GO:0050773 59 0.018
regulation of peptide transport GO:0090087 87 0.018
Rat
regulation of secretion by cell GO:1903530 208 0.018
Rat
regulation of protein complex assembly GO:0043254 33 0.018
regulation of erk1 and erk2 cascade GO:0070372 41 0.018
developmental growth GO:0048589 100 0.018
Fly
morphogenesis of an epithelium GO:0002009 20 0.018
cellular macromolecular complex assembly GO:0034622 58 0.018
alternative mrna splicing via spliceosome GO:0000380 4 0.018
metal ion transport GO:0030001 289 0.018
g protein coupled receptor signaling pathway GO:0007186 242 0.018
ion transmembrane transport GO:0034220 365 0.018
regulation of blood vessel size GO:0050880 89 0.018
gonad development GO:0008406 104 0.018
muscle system process GO:0003012 115 0.017
organophosphate biosynthetic process GO:0090407 143 0.017
actin mediated cell contraction GO:0070252 12 0.017
positive regulation of ion transport GO:0043270 94 0.017
monocarboxylic acid metabolic process GO:0032787 152 0.017
lymphocyte activation GO:0046649 43 0.017
formation of primary germ layer GO:0001704 1 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
positive regulation of smooth muscle cell migration GO:0014911 27 0.017
negative regulation of molecular function GO:0044092 133 0.017
carboxylic acid biosynthetic process GO:0046394 83 0.017
multicellular organismal signaling GO:0035637 44 0.017
regulation of neurological system process GO:0031644 43 0.017
male sex differentiation GO:0046661 64 0.017
hepaticobiliary system development GO:0061008 90 0.017
positive regulation of nucleotide metabolic process GO:0045981 91 0.016
negative regulation of neurogenesis GO:0050768 78 0.016
cytokine mediated signaling pathway GO:0019221 43 0.016
sex differentiation GO:0007548 113 0.016

Pde4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.041
disease of cellular proliferation DOID:14566 0 0.041
organ system cancer DOID:0050686 0 0.028
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
gastrointestinal system cancer DOID:3119 0 0.019
disease of metabolism DOID:0014667 0 0.019
stomach cancer DOID:10534 0 0.016