Rattus norvegicus

2 known processes

Man2c1

mannosidase, alpha, class 2C, member 1

(Aliases: MGC93158)

Man2c1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein phosphorylation GO:0006468 345 0.092
regulation of cellular protein metabolic process GO:0032268 267 0.082
response to peptide GO:1901652 292 0.080
response to external biotic stimulus GO:0043207 221 0.078
transmembrane transport GO:0055085 412 0.075
regulation of protein modification process GO:0031399 194 0.066
inorganic ion transmembrane transport GO:0098660 229 0.060
lipid metabolic process GO:0006629 283 0.058
cation transport GO:0006812 382 0.056
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.055
rna metabolic process GO:0016070 406 0.055
programmed cell death GO:0012501 392 0.054
regulation of nervous system development GO:0051960 264 0.053
carbohydrate derivative metabolic process GO:1901135 346 0.052
positive regulation of transport GO:0051050 245 0.050
response to peptide hormone GO:0043434 278 0.050
negative regulation of macromolecule metabolic process GO:0010605 260 0.050
regulation of nucleic acid templated transcription GO:1903506 380 0.049
positive regulation of phosphorylation GO:0042327 177 0.049
single organism reproductive process GO:0044702 297 0.048
negative regulation of protein metabolic process GO:0051248 114 0.048
cellular lipid metabolic process GO:0044255 208 0.048
negative regulation of metabolic process GO:0009892 331 0.047
positive regulation of rna metabolic process GO:0051254 203 0.047
regulation of phosphorylation GO:0042325 248 0.046
regulation of multicellular organismal development GO:2000026 376 0.045
cellular catabolic process GO:0044248 295 0.044
positive regulation of multicellular organismal process GO:0051240 387 0.044
insulin like growth factor receptor signaling pathway GO:0048009 3 0.043
phosphatidylethanolamine metabolic process GO:0046337 1 0.042
positive regulation of rna biosynthetic process GO:1902680 197 0.041
response to decreased oxygen levels GO:0036293 237 0.041
regulation of neuron differentiation GO:0045664 208 0.040
protein oligomerization GO:0051259 191 0.039
regulation of molecular function GO:0065009 398 0.037
regulation of neuron projection development GO:0010975 161 0.036
homeostatic process GO:0042592 331 0.036
protein complex biogenesis GO:0070271 263 0.036
macromolecule localization GO:0033036 252 0.036
organophosphate metabolic process GO:0019637 370 0.036
intracellular signal transduction GO:0035556 314 0.036
ion transmembrane transport GO:0034220 365 0.035
catabolic process GO:0009056 351 0.035
synaptic growth at neuromuscular junction GO:0051124 1 0.035
protein homooligomerization GO:0051260 91 0.034
regulation of rna metabolic process GO:0051252 391 0.034
negative regulation of phosphate metabolic process GO:0045936 80 0.034
macromolecular complex subunit organization GO:0043933 339 0.033
regulation of neurogenesis GO:0050767 247 0.033
chemical homeostasis GO:0048878 292 0.033
reproductive process GO:0022414 372 0.033
cation transmembrane transport GO:0098655 263 0.033
regulation of signal transduction GO:0009966 318 0.033
positive regulation of cellular biosynthetic process GO:0031328 295 0.032
response to extracellular stimulus GO:0009991 380 0.032
regulation of rna biosynthetic process GO:2001141 381 0.031
positive regulation of phosphorus metabolic process GO:0010562 262 0.031
regulation of cell proliferation GO:0042127 359 0.031
inorganic cation transmembrane transport GO:0098662 202 0.031
regulation of cell differentiation GO:0045595 320 0.031
neurological system process GO:0050877 219 0.031
negative regulation of cell proliferation GO:0008285 119 0.031
immune effector process GO:0002252 53 0.031
nucleic acid templated transcription GO:0097659 379 0.031
protein complex subunit organization GO:0071822 302 0.031
organic acid metabolic process GO:0006082 292 0.030
carboxylic acid metabolic process GO:0019752 289 0.030
secretion by cell GO:0032940 248 0.030
response to oxygen levels GO:0070482 265 0.030
regulation of phosphate metabolic process GO:0019220 349 0.030
regulation of cell development GO:0060284 263 0.029
cell projection organization GO:0030030 302 0.028
central nervous system development GO:0007417 311 0.028
cellular amine metabolic process GO:0044106 38 0.028
organonitrogen compound biosynthetic process GO:1901566 167 0.028
metal ion transport GO:0030001 289 0.028
response to ethanol GO:0045471 162 0.028
nucleotide metabolic process GO:0009117 279 0.028
anatomical structure morphogenesis GO:0009653 298 0.028
cytosolic calcium ion homeostasis GO:0051480 140 0.028
positive regulation of biosynthetic process GO:0009891 319 0.028
immune response GO:0006955 104 0.027
regulation of protein phosphorylation GO:0001932 183 0.027
cellular response to stress GO:0033554 269 0.027
regulation of transcription dna templated GO:0006355 374 0.027
apoptotic process GO:0006915 381 0.026
response to fungicide GO:0060992 20 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
cytoskeleton organization GO:0007010 111 0.026
brain development GO:0007420 247 0.026
nitrogen compound transport GO:0071705 229 0.026
cellular component assembly GO:0022607 360 0.026
oxoacid metabolic process GO:0043436 290 0.026
proteolysis GO:0006508 175 0.026
lipid biosynthetic process GO:0008610 128 0.026
negative regulation of cell differentiation GO:0045596 99 0.026
neuron differentiation GO:0030182 368 0.025
cellular component movement GO:0006928 248 0.025
tube formation GO:0035148 3 0.025
response to wounding GO:0009611 254 0.025
single organism biosynthetic process GO:0044711 342 0.024
protein heterooligomerization GO:0051291 89 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.024
divalent inorganic cation homeostasis GO:0072507 165 0.024
transcription dna templated GO:0006351 377 0.024
response to nutrient levels GO:0031667 370 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
regulation of cellular component organization GO:0051128 368 0.023
single organism catabolic process GO:0044712 283 0.023
cellular response to peptide hormone stimulus GO:0071375 120 0.023
regulation of transmembrane transport GO:0034762 122 0.023
angioblast cell migration GO:0035476 1 0.023
neuron neuron synaptic transmission GO:0007270 60 0.023
memory GO:0007613 54 0.022
reproduction GO:0000003 245 0.022
head development GO:0060322 247 0.022
neuron projection development GO:0031175 273 0.022
negative regulation of innate immune response GO:0045824 4 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
regulation of transferase activity GO:0051338 123 0.021
cellular divalent inorganic cation homeostasis GO:0072503 162 0.021
response to cytokine GO:0034097 215 0.021
cellular metal ion homeostasis GO:0006875 172 0.021
negative regulation of cellular component organization GO:0051129 83 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
response to acid chemical GO:0001101 222 0.021
cellular calcium ion homeostasis GO:0006874 160 0.021
response to insulin GO:0032868 133 0.021
microtubule organizing center organization GO:0031023 1 0.021
urinary bladder smooth muscle contraction GO:0014832 4 0.021
cellular homeostasis GO:0019725 252 0.021
immune system process GO:0002376 204 0.021
learning or memory GO:0007611 90 0.021
cellular cation homeostasis GO:0030003 180 0.021
regulation of apoptotic process GO:0042981 335 0.021
metal ion homeostasis GO:0055065 186 0.020
regulation of catalytic activity GO:0050790 304 0.020
positive regulation of nervous system development GO:0051962 178 0.020
carbohydrate derivative biosynthetic process GO:1901137 124 0.020
blood circulation GO:0008015 183 0.020
organophosphate biosynthetic process GO:0090407 143 0.020
cellular component biogenesis GO:0044085 368 0.020
cellular response to nitrogen compound GO:1901699 210 0.020
regulation of immune system process GO:0002682 123 0.020
positive regulation of developmental process GO:0051094 283 0.020
cellular chemical homeostasis GO:0055082 247 0.020
negative regulation of multicellular organismal process GO:0051241 203 0.020
calcium ion transmembrane transport GO:0070588 70 0.020
tissue development GO:0009888 252 0.020
positive regulation of cellular protein metabolic process GO:0032270 167 0.020
negative regulation of phosphorus metabolic process GO:0010563 80 0.020
cellular ketone metabolic process GO:0042180 51 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
negative regulation of signaling GO:0023057 157 0.020
calcium ion transport GO:0006816 131 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
spindle organization GO:0007051 2 0.019
negative regulation of nervous system development GO:0051961 79 0.019
cell cell signaling GO:0007267 335 0.019
forebrain development GO:0030900 98 0.019
negative regulation of protein phosphorylation GO:0001933 44 0.019
negative regulation of cell communication GO:0010648 158 0.019
small molecule biosynthetic process GO:0044283 124 0.019
calcium ion homeostasis GO:0055074 162 0.019
positive regulation of neurogenesis GO:0050769 165 0.019
response to nutrient GO:0007584 248 0.019
circulatory system process GO:0003013 183 0.019
monovalent inorganic cation transport GO:0015672 172 0.019
ion homeostasis GO:0050801 212 0.018
glycerolipid metabolic process GO:0046486 67 0.018
rna biosynthetic process GO:0032774 380 0.018
cation homeostasis GO:0055080 195 0.018
peptide biosynthetic process GO:0043043 3 0.018
protein localization GO:0008104 191 0.018
cognition GO:0050890 92 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
alcohol biosynthetic process GO:0046165 38 0.018
peptidyl amino acid modification GO:0018193 126 0.018
regulation of ion transmembrane transport GO:0034765 121 0.018
negative regulation of neurogenesis GO:0050768 78 0.018
regulation of immune response GO:0050776 55 0.017
regulation of cation channel activity GO:2001257 23 0.017
regulation of protein metabolic process GO:0051246 289 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
multicellular organism reproduction GO:0032504 233 0.017
protein import into nucleus GO:0006606 35 0.017
cellular ion homeostasis GO:0006873 184 0.017
cellular response to oxygen containing compound GO:1901701 386 0.017
negative regulation of molecular function GO:0044092 133 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
regulation of programmed cell death GO:0043067 341 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
acute phase response GO:0006953 20 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
regulation of system process GO:0044057 208 0.017
amine metabolic process GO:0009308 38 0.017
single organism nuclear import GO:1902593 35 0.017
response to hypoxia GO:0001666 231 0.017
positive regulation of response to stimulus GO:0048584 285 0.017
regulation of proteasomal protein catabolic process GO:0061136 4 0.017
synaptic transmission GO:0007268 235 0.016
alcohol metabolic process GO:0006066 77 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.016
organelle organization GO:0006996 266 0.016
regulation of cellular localization GO:0060341 263 0.016
cell migration GO:0016477 197 0.016
regulation of metal ion transport GO:0010959 118 0.016
regulation of transporter activity GO:0032409 50 0.016
cardiovascular system development GO:0072358 134 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
t cell receptor signaling pathway GO:0050852 1 0.016
nucleocytoplasmic transport GO:0006913 48 0.016
renal system development GO:0072001 67 0.016
regulation of cell growth GO:0001558 85 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
gastrulation GO:0007369 2 0.016
centrosome organization GO:0051297 1 0.015
macromolecular complex assembly GO:0065003 273 0.015
protein ubiquitination GO:0016567 28 0.015
regulation of ion transport GO:0043269 245 0.015
locomotion GO:0040011 237 0.015
regulation of kinase activity GO:0043549 117 0.015
cellular response to endogenous stimulus GO:0071495 377 0.015
organic hydroxy compound biosynthetic process GO:1901617 51 0.015
ras protein signal transduction GO:0007265 29 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
cellular response to cytokine stimulus GO:0071345 127 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
embryonic pattern specification GO:0009880 1 0.015
positive regulation of signaling GO:0023056 270 0.015
neuron development GO:0048666 286 0.015
epithelial tube formation GO:0072175 3 0.015
growth GO:0040007 165 0.015
mitotic spindle organization GO:0007052 2 0.015
inflammatory response GO:0006954 150 0.015
cellular response to peptide GO:1901653 133 0.015
divalent inorganic cation transport GO:0072511 134 0.015
neuron projection morphogenesis GO:0048812 122 0.015
cell cell signaling involved in cell fate commitment GO:0045168 2 0.014
regulation of cell projection organization GO:0031344 175 0.014
cytoplasmic transport GO:0016482 115 0.014
establishment of protein localization GO:0045184 141 0.014
regulation of secretion by cell GO:1903530 208 0.014
histone h3 k9 methylation GO:0051567 1 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
positive regulation of homeostatic process GO:0032846 49 0.014
cellular protein localization GO:0034613 122 0.014
intracellular transport GO:0046907 185 0.014
response to carbohydrate GO:0009743 183 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
protein complex assembly GO:0006461 263 0.013
regulation of protein kinase activity GO:0045859 105 0.013
formation of primary germ layer GO:0001704 1 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
cellular amide metabolic process GO:0043603 44 0.013
morphogenesis of embryonic epithelium GO:0016331 3 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
phospholipid metabolic process GO:0006644 61 0.013
regulation of small gtpase mediated signal transduction GO:0051056 48 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
hormone mediated signaling pathway GO:0009755 23 0.013
negative regulation of neuron differentiation GO:0045665 62 0.013
eye morphogenesis GO:0048592 4 0.013
regulation of response to wounding GO:1903034 69 0.013
regulation of cellular component movement GO:0051270 150 0.013
regulation of anatomical structure size GO:0090066 135 0.013
single organism organelle organization GO:1902589 180 0.013
sequestering of metal ion GO:0051238 9 0.012
signal release GO:0023061 145 0.012
regulation of transmembrane transporter activity GO:0022898 49 0.012
macromolecule catabolic process GO:0009057 58 0.012
urinary tract smooth muscle contraction GO:0014848 4 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
response to organophosphorus GO:0046683 102 0.012
sequestering of calcium ion GO:0051208 8 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
positive regulation of ion transport GO:0043270 94 0.012
regulation of response to stress GO:0080134 126 0.012
gamete generation GO:0007276 124 0.012
negative regulation of cell death GO:0060548 229 0.012
response to inorganic substance GO:0010035 377 0.012
programmed necrotic cell death GO:0097300 2 0.012
regulation of response to external stimulus GO:0032101 106 0.012
intracellular protein transport GO:0006886 79 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
regulation of peptide transport GO:0090087 87 0.012
positive regulation of immune system process GO:0002684 90 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
carboxylic acid transport GO:0046942 115 0.012
heart process GO:0003015 57 0.012
positive regulation of cell communication GO:0010647 271 0.012
positive regulation of transcription factor import into nucleus GO:0042993 4 0.012
hormone secretion GO:0046879 115 0.012
regulation of blood circulation GO:1903522 110 0.012
negative regulation of response to stimulus GO:0048585 155 0.011
divalent metal ion transport GO:0070838 132 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
limbic system development GO:0021761 38 0.011
cellular response to oxygen levels GO:0071453 60 0.011
synaptic transmission glutamatergic GO:0035249 33 0.011
anion transport GO:0006820 178 0.011
rna localization GO:0006403 4 0.011
regulation of hormone secretion GO:0046883 106 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
organic substance catabolic process GO:1901575 316 0.011
negative regulation of cell development GO:0010721 82 0.011
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.011
developmental growth GO:0048589 100 0.011
vascular process in circulatory system GO:0003018 96 0.011
telencephalon development GO:0021537 62 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
axis specification GO:0009798 4 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
protein localization to organelle GO:0033365 57 0.011
circulatory system development GO:0072359 134 0.010
response to monosaccharide GO:0034284 159 0.010
sensory perception GO:0007600 101 0.010
cellular response to glucose stimulus GO:0071333 65 0.010
oxidation reduction process GO:0055114 304 0.010
positive regulation of molecular function GO:0044093 230 0.010
behavior GO:0007610 205 0.010
regulation of phosphorus metabolic process GO:0051174 349 0.010
defense response GO:0006952 194 0.010
positive regulation of signal transduction GO:0009967 175 0.010
nucleoside metabolic process GO:0009116 179 0.010
single organism intracellular transport GO:1902582 166 0.010
negative regulation of nf kappab transcription factor activity GO:0032088 4 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
cellular response to hexose stimulus GO:0071331 65 0.010
pallium development GO:0021543 42 0.010
glucose homeostasis GO:0042593 75 0.010
regulation of homeostatic process GO:0032844 101 0.010
nucleotide biosynthetic process GO:0009165 98 0.010
neural tube formation GO:0001841 1 0.010
synapse organization GO:0050808 46 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010

Man2c1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
disease of metabolism DOID:0014667 0 0.020
inherited metabolic disorder DOID:655 0 0.017
myopathy DOID:423 0 0.016
muscular disease DOID:0080000 0 0.016
musculoskeletal system disease DOID:17 0 0.016
muscle tissue disease DOID:66 0 0.016
muscular dystrophy DOID:9884 0 0.013
carbohydrate metabolic disorder DOID:2978 0 0.013
central nervous system disease DOID:331 0 0.011