Rattus norvegicus

0 known processes

Ddi2

DNA-damage inducible protein 2

(Aliases: RGD1311815)

Ddi2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.098
intracellular signal transduction GO:0035556 314 0.077
organic substance catabolic process GO:1901575 316 0.071
catabolic process GO:0009056 351 0.070
macromolecular complex subunit organization GO:0043933 339 0.062
anatomical structure morphogenesis GO:0009653 298 0.055
cellular catabolic process GO:0044248 295 0.055
cellular component biogenesis GO:0044085 368 0.053
single organism catabolic process GO:0044712 283 0.053
cellular component assembly GO:0022607 360 0.052
neuron differentiation GO:0030182 368 0.049
organophosphate metabolic process GO:0019637 370 0.049
regulation of molecular function GO:0065009 398 0.048
positive regulation of transcription dna templated GO:0045893 197 0.048
macromolecule localization GO:0033036 252 0.046
positive regulation of signaling GO:0023056 270 0.045
regulation of intracellular signal transduction GO:1902531 218 0.044
ras protein signal transduction GO:0007265 29 0.043
regulation of phosphate metabolic process GO:0019220 349 0.043
cell projection organization GO:0030030 302 0.041
positive regulation of phosphorus metabolic process GO:0010562 262 0.041
regulation of cell differentiation GO:0045595 320 0.041
positive regulation of molecular function GO:0044093 230 0.040
carbohydrate derivative metabolic process GO:1901135 346 0.039
regulation of signal transduction GO:0009966 318 0.039
regulation of rna biosynthetic process GO:2001141 381 0.038
cellular amino acid metabolic process GO:0006520 107 0.037
regulation of multicellular organismal development GO:2000026 376 0.037
response to peptide hormone GO:0043434 278 0.036
protein phosphorylation GO:0006468 345 0.035
regulation of nervous system development GO:0051960 264 0.035
nucleobase containing small molecule metabolic process GO:0055086 316 0.035
aging GO:0007568 241 0.035
organic acid metabolic process GO:0006082 292 0.035
regulation of cell development GO:0060284 263 0.035
nucleoside phosphate metabolic process GO:0006753 283 0.034
protein complex assembly GO:0006461 263 0.034
cellular amine metabolic process GO:0044106 38 0.034
regulation of cellular component organization GO:0051128 368 0.034
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.033
organelle organization GO:0006996 266 0.033
regulation of neurogenesis GO:0050767 247 0.033
apoptotic process GO:0006915 381 0.033
regulation of proteasomal protein catabolic process GO:0061136 4 0.032
nucleic acid templated transcription GO:0097659 379 0.032
regulation of transcription dna templated GO:0006355 374 0.031
positive regulation of phosphate metabolic process GO:0045937 262 0.031
programmed cell death GO:0012501 392 0.031
rna metabolic process GO:0016070 406 0.030
carboxylic acid metabolic process GO:0019752 289 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.029
macromolecular complex assembly GO:0065003 273 0.029
regulation of programmed cell death GO:0043067 341 0.029
rna biosynthetic process GO:0032774 380 0.029
amine metabolic process GO:0009308 38 0.029
protein complex subunit organization GO:0071822 302 0.029
positive regulation of catalytic activity GO:0043085 184 0.028
response to lipopolysaccharide GO:0032496 191 0.028
regulation of nucleic acid templated transcription GO:1903506 380 0.028
regulation of cell proliferation GO:0042127 359 0.028
cellular response to oxygen containing compound GO:1901701 386 0.028
positive regulation of multicellular organismal process GO:0051240 387 0.028
oxoacid metabolic process GO:0043436 290 0.027
positive regulation of response to stimulus GO:0048584 285 0.027
cellular response to endogenous stimulus GO:0071495 377 0.027
regulation of catabolic process GO:0009894 113 0.027
regulation of cell projection organization GO:0031344 175 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.026
reproductive process GO:0022414 372 0.026
transmembrane transport GO:0055085 412 0.026
organonitrogen compound catabolic process GO:1901565 179 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
protein complex biogenesis GO:0070271 263 0.026
purine containing compound metabolic process GO:0072521 253 0.026
cellular response to nitrogen compound GO:1901699 210 0.025
cellular ketone metabolic process GO:0042180 51 0.025
cellular component morphogenesis GO:0032989 155 0.025
regulation of neuron differentiation GO:0045664 208 0.025
transcription dna templated GO:0006351 377 0.025
positive regulation of cell communication GO:0010647 271 0.025
nucleoside metabolic process GO:0009116 179 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
proteolysis GO:0006508 175 0.024
multi organism reproductive process GO:0044703 262 0.024
glycosyl compound metabolic process GO:1901657 182 0.024
purine ribonucleotide metabolic process GO:0009150 227 0.024
lipid metabolic process GO:0006629 283 0.023
cellular response to growth factor stimulus GO:0071363 162 0.023
ribonucleotide metabolic process GO:0009259 231 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
small gtpase mediated signal transduction GO:0007264 36 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
negative regulation of metabolic process GO:0009892 331 0.023
response to cytokine GO:0034097 215 0.023
response to metal ion GO:0010038 253 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.022
regulation of rna metabolic process GO:0051252 391 0.022
regulation of phosphorus metabolic process GO:0051174 349 0.022
neuron development GO:0048666 286 0.022
response to inorganic substance GO:0010035 377 0.022
purine nucleoside triphosphate metabolic process GO:0009144 141 0.022
response to decreased oxygen levels GO:0036293 237 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.021
carbohydrate derivative catabolic process GO:1901136 147 0.021
regulation of apoptotic process GO:0042981 335 0.021
purine containing compound catabolic process GO:0072523 138 0.021
tissue development GO:0009888 252 0.021
enzyme linked receptor protein signaling pathway GO:0007167 116 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
purine nucleoside metabolic process GO:0042278 169 0.021
response to nutrient levels GO:0031667 370 0.021
cellular lipid metabolic process GO:0044255 208 0.021
cellular response to cytokine stimulus GO:0071345 127 0.020
positive regulation of rna metabolic process GO:0051254 203 0.020
regulation of catalytic activity GO:0050790 304 0.020
purine ribonucleoside metabolic process GO:0046128 168 0.020
response to oxygen levels GO:0070482 265 0.020
response to biotic stimulus GO:0009607 226 0.020
reproduction GO:0000003 245 0.020
positive regulation of biosynthetic process GO:0009891 319 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
positive regulation of developmental process GO:0051094 283 0.019
response to growth factor GO:0070848 189 0.019
nucleoside phosphate catabolic process GO:1901292 140 0.019
single organism intracellular transport GO:1902582 166 0.019
positive regulation of signal transduction GO:0009967 175 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
aromatic compound catabolic process GO:0019439 168 0.019
neuron projection development GO:0031175 273 0.019
ribonucleoside metabolic process GO:0009119 174 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
secretion GO:0046903 307 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
homeostatic process GO:0042592 331 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
organic acid biosynthetic process GO:0016053 83 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
regulation of neuron projection development GO:0010975 161 0.018
neuron death GO:0070997 127 0.018
growth GO:0040007 165 0.018
positive regulation of gene expression GO:0010628 244 0.018
intracellular transport GO:0046907 185 0.017
ribonucleoside triphosphate metabolic process GO:0009199 141 0.017
cellular response to lipid GO:0071396 201 0.017
single organism reproductive process GO:0044702 297 0.017
positive regulation of cell development GO:0010720 176 0.017
regulation of cellular catabolic process GO:0031329 101 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
anion transport GO:0006820 178 0.017
cellular response to stress GO:0033554 269 0.017
purine nucleotide catabolic process GO:0006195 136 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.017
chemical homeostasis GO:0048878 292 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
protein oligomerization GO:0051259 191 0.017
multicellular organism growth GO:0035264 1 0.017
nucleotide metabolic process GO:0009117 279 0.017
circulatory system development GO:0072359 134 0.017
cation transmembrane transport GO:0098655 263 0.016
metal ion transport GO:0030001 289 0.016
cellular response to peptide GO:1901653 133 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
multicellular organism reproduction GO:0032504 233 0.016
peptide biosynthetic process GO:0043043 3 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
response to transition metal nanoparticle GO:1990267 122 0.016
negative regulation of cell death GO:0060548 229 0.016
cation transport GO:0006812 382 0.016
cellular homeostasis GO:0019725 252 0.016
cardiovascular system development GO:0072358 134 0.016
small molecule biosynthetic process GO:0044283 124 0.016
regulation of hydrolase activity GO:0051336 143 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
purine ribonucleoside catabolic process GO:0046130 124 0.016
regulation of cellular localization GO:0060341 263 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
organic anion transport GO:0015711 132 0.015
organophosphate catabolic process GO:0046434 148 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.015
regulation of protein metabolic process GO:0051246 289 0.015
peptidyl amino acid modification GO:0018193 126 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
locomotion GO:0040011 237 0.015
heterocycle catabolic process GO:0046700 167 0.015
nucleotide catabolic process GO:0009166 139 0.015
response to organophosphorus GO:0046683 102 0.015
nucleoside catabolic process GO:0009164 126 0.015
cation homeostasis GO:0055080 195 0.015
purine ribonucleotide catabolic process GO:0009154 136 0.015
ion homeostasis GO:0050801 212 0.015
response to oxidative stress GO:0006979 186 0.015
neurological system process GO:0050877 219 0.015
brain development GO:0007420 247 0.015
carboxylic acid biosynthetic process GO:0046394 83 0.015
carboxylic acid transport GO:0046942 115 0.015
regulation of response to stress GO:0080134 126 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
cellular response to hormone stimulus GO:0032870 247 0.014
ribonucleotide catabolic process GO:0009261 136 0.014
single organism organelle organization GO:1902589 180 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
single organism biosynthetic process GO:0044711 342 0.014
regulation of transferase activity GO:0051338 123 0.014
positive regulation of cellular catabolic process GO:0031331 71 0.014
tube development GO:0035295 89 0.014
positive regulation of protein modification process GO:0031401 142 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
positive regulation of cell death GO:0010942 184 0.014
regulation of cell morphogenesis GO:0022604 77 0.014
positive regulation of nervous system development GO:0051962 178 0.014
chromosome segregation GO:0007059 2 0.014
negative regulation of rna biosynthetic process GO:1902679 118 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
nitrogen compound transport GO:0071705 229 0.014
sexual reproduction GO:0019953 148 0.014
rho protein signal transduction GO:0007266 11 0.014
negative regulation of developmental process GO:0051093 125 0.013
regulation of system process GO:0044057 208 0.013
cell cell signaling GO:0007267 335 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
protein transport GO:0015031 132 0.013
synaptic transmission GO:0007268 235 0.013
head development GO:0060322 247 0.013
nucleoside triphosphate catabolic process GO:0009143 123 0.013
positive regulation of hydrolase activity GO:0051345 86 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
cellular component movement GO:0006928 248 0.013
monocarboxylic acid metabolic process GO:0032787 152 0.013
muscle system process GO:0003012 115 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
central nervous system development GO:0007417 311 0.013
positive regulation of cell proliferation GO:0008284 249 0.013
response to peptide GO:1901652 292 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
cell morphogenesis GO:0000902 142 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
multi multicellular organism process GO:0044706 138 0.012
response to extracellular stimulus GO:0009991 380 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
positive regulation of catabolic process GO:0009896 78 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
secretion by cell GO:0032940 248 0.012
response to other organism GO:0051707 220 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
muscle structure development GO:0061061 87 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
cellular response to molecule of bacterial origin GO:0071219 56 0.012
circulatory system process GO:0003013 183 0.012
blood circulation GO:0008015 183 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
response to acid chemical GO:0001101 222 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
anterior posterior pattern specification GO:0009952 1 0.011
gtp metabolic process GO:0046039 72 0.011
regulation of protein modification process GO:0031399 194 0.011
axis specification GO:0009798 4 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
vesicle mediated transport GO:0016192 181 0.011
regulation of ion transport GO:0043269 245 0.011
ion transmembrane transport GO:0034220 365 0.011
regulation of anatomical structure size GO:0090066 135 0.011
regulation of nucleotide catabolic process GO:0030811 65 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
embryonic pattern specification GO:0009880 1 0.011
cytoplasmic transport GO:0016482 115 0.011
spindle organization GO:0007051 2 0.011
response to nutrient GO:0007584 248 0.011
positive regulation of transport GO:0051050 245 0.011
cellular cation homeostasis GO:0030003 180 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
negative regulation of transport GO:0051051 136 0.011
establishment of protein localization GO:0045184 141 0.011
response to estrogen GO:0043627 232 0.011
response to insulin GO:0032868 133 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
cytoskeleton organization GO:0007010 111 0.010
guanosine containing compound catabolic process GO:1901069 71 0.010
regulation of protein localization GO:0032880 81 0.010
organic acid transport GO:0015849 116 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
response to purine containing compound GO:0014074 126 0.010
developmental growth GO:0048589 100 0.010
regulation of protein phosphorylation GO:0001932 183 0.010
ribonucleoside triphosphate catabolic process GO:0009203 122 0.010
cell migration GO:0016477 197 0.010
regulation of secretion GO:0051046 224 0.010
cellular chemical homeostasis GO:0055082 247 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.010
regulation of small gtpase mediated signal transduction GO:0051056 48 0.010
negative regulation of gene expression GO:0010629 199 0.010
regulation of mapk cascade GO:0043408 116 0.010

Ddi2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.027
disease of anatomical entity DOID:7 0 0.027
musculoskeletal system disease DOID:17 0 0.027
muscle tissue disease DOID:66 0 0.027
nervous system disease DOID:863 0 0.016
myopathy DOID:423 0 0.012
central nervous system disease DOID:331 0 0.011