Rattus norvegicus

0 known processes

Pmel

premelanosome protein

(Aliases: Si,Silv)

Pmel biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell projection organization GO:0030030 302 0.073
reproduction GO:0000003 245 0.051
reproductive process GO:0022414 372 0.050
multicellular organism reproduction GO:0032504 233 0.049
neuron development GO:0048666 286 0.047
central nervous system development GO:0007417 311 0.047
response to reactive oxygen species GO:0000302 120 0.046
response to inorganic substance GO:0010035 377 0.044
cellular lipid metabolic process GO:0044255 208 0.041
response to oxidative stress GO:0006979 186 0.039
regulation of signal transduction GO:0009966 318 0.038
oxoacid metabolic process GO:0043436 290 0.038
programmed cell death GO:0012501 392 0.037
neurological system process GO:0050877 219 0.036
regulation of multicellular organismal development GO:2000026 376 0.033
cellular component biogenesis GO:0044085 368 0.030
cell motility GO:0048870 202 0.030
regulation of neurogenesis GO:0050767 247 0.029
response to hypoxia GO:0001666 231 0.029
response to growth factor GO:0070848 189 0.029
apoptotic process GO:0006915 381 0.029
response to metal ion GO:0010038 253 0.029
response to oxygen levels GO:0070482 265 0.029
cellular component movement GO:0006928 248 0.028
cellular component assembly GO:0022607 360 0.028
cellular response to oxygen containing compound GO:1901701 386 0.028
response to wounding GO:0009611 254 0.028
neuron projection development GO:0031175 273 0.028
brain development GO:0007420 247 0.027
cellular response to stress GO:0033554 269 0.027
regulation of cell development GO:0060284 263 0.027
response to other organism GO:0051707 220 0.027
cellular amine metabolic process GO:0044106 38 0.027
regulation of apoptotic process GO:0042981 335 0.026
head development GO:0060322 247 0.026
response to alkaloid GO:0043279 132 0.026
response to decreased oxygen levels GO:0036293 237 0.026
neuron differentiation GO:0030182 368 0.025
rna metabolic process GO:0016070 406 0.025
multi organism reproductive process GO:0044703 262 0.025
response to nutrient levels GO:0031667 370 0.025
response to purine containing compound GO:0014074 126 0.025
rna biosynthetic process GO:0032774 380 0.024
regulation of nervous system development GO:0051960 264 0.024
positive regulation of developmental process GO:0051094 283 0.024
response to lipopolysaccharide GO:0032496 191 0.024
ion transmembrane transport GO:0034220 365 0.023
protein localization GO:0008104 191 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
organic anion transport GO:0015711 132 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.023
anatomical structure morphogenesis GO:0009653 298 0.022
chemical homeostasis GO:0048878 292 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
gliogenesis GO:0042063 93 0.022
protein complex biogenesis GO:0070271 263 0.022
regulation of programmed cell death GO:0043067 341 0.022
negative regulation of cell differentiation GO:0045596 99 0.021
single organism biosynthetic process GO:0044711 342 0.021
response to acid chemical GO:0001101 222 0.021
regulation of cell differentiation GO:0045595 320 0.021
negative regulation of apoptotic process GO:0043066 181 0.020
regulation of cellular component organization GO:0051128 368 0.020
cellular ketone metabolic process GO:0042180 51 0.020
positive regulation of gene expression GO:0010628 244 0.020
organic acid metabolic process GO:0006082 292 0.020
cellular response to endogenous stimulus GO:0071495 377 0.020
negative regulation of programmed cell death GO:0043069 183 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
response to extracellular stimulus GO:0009991 380 0.020
response to ethanol GO:0045471 162 0.019
response to nutrient GO:0007584 248 0.019
sex differentiation GO:0007548 113 0.019
regulation of cell migration GO:0030334 128 0.019
nucleic acid templated transcription GO:0097659 379 0.019
cellular amino acid metabolic process GO:0006520 107 0.019
macromolecule localization GO:0033036 252 0.019
nitrogen compound transport GO:0071705 229 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
behavior GO:0007610 205 0.018
response to hydrogen peroxide GO:0042542 89 0.018
protein complex assembly GO:0006461 263 0.018
locomotion GO:0040011 237 0.018
intracellular signal transduction GO:0035556 314 0.018
cellular response to external stimulus GO:0071496 118 0.018
carboxylic acid metabolic process GO:0019752 289 0.018
glial cell differentiation GO:0010001 65 0.018
lipid metabolic process GO:0006629 283 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
regulation of rna metabolic process GO:0051252 391 0.017
cellular catabolic process GO:0044248 295 0.017
positive regulation of multicellular organismal process GO:0051240 387 0.017
sexual reproduction GO:0019953 148 0.017
axon development GO:0061564 96 0.017
single organism reproductive process GO:0044702 297 0.017
cellular response to lipopolysaccharide GO:0071222 55 0.017
axis specification GO:0009798 4 0.017
regulation of transcription dna templated GO:0006355 374 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
cellular response to lipid GO:0071396 201 0.016
positive regulation of cellular biosynthetic process GO:0031328 295 0.016
macromolecular complex assembly GO:0065003 273 0.016
protein complex subunit organization GO:0071822 302 0.016
regulation of neuron projection development GO:0010975 161 0.016
anion transport GO:0006820 178 0.016
regulation of rna biosynthetic process GO:2001141 381 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
negative regulation of neurogenesis GO:0050768 78 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.015
negative regulation of cell development GO:0010721 82 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.015
aging GO:0007568 241 0.015
regulation of anatomical structure size GO:0090066 135 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
regulation of protein metabolic process GO:0051246 289 0.015
establishment of protein localization GO:0045184 141 0.015
positive regulation of nervous system development GO:0051962 178 0.015
organelle organization GO:0006996 266 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
protein oligomerization GO:0051259 191 0.014
transcription dna templated GO:0006351 377 0.014
monocarboxylic acid metabolic process GO:0032787 152 0.014
cell migration GO:0016477 197 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
neuron neuron synaptic transmission GO:0007270 60 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
intracellular protein transport GO:0006886 79 0.014
gamete generation GO:0007276 124 0.014
regulation of cell motility GO:2000145 131 0.014
homeostatic process GO:0042592 331 0.014
cell type specific apoptotic process GO:0097285 134 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
regulation of cell projection organization GO:0031344 175 0.014
isoprenoid metabolic process GO:0006720 45 0.014
positive regulation of biosynthetic process GO:0009891 319 0.014
synaptic transmission GO:0007268 235 0.014
response to toxic substance GO:0009636 133 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
learning or memory GO:0007611 90 0.013
regulation of cellular component movement GO:0051270 150 0.013
cellular response to organic cyclic compound GO:0071407 202 0.013
hormone metabolic process GO:0042445 69 0.013
amine metabolic process GO:0009308 38 0.013
positive regulation of molecular function GO:0044093 230 0.013
regulation of cellular localization GO:0060341 263 0.013
organophosphate metabolic process GO:0019637 370 0.013
adult locomotory behavior GO:0008344 4 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
cytoplasmic transport GO:0016482 115 0.013
negative regulation of cell death GO:0060548 229 0.013
regulation of locomotion GO:0040012 148 0.012
single organism intracellular transport GO:1902582 166 0.012
cellular chemical homeostasis GO:0055082 247 0.012
negative regulation of gene expression GO:0010629 199 0.012
growth GO:0040007 165 0.012
chemosensory behavior GO:0007635 2 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
regulation of nucleic acid templated transcription GO:1903506 380 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
neuron death GO:0070997 127 0.012
macromolecular complex subunit organization GO:0043933 339 0.012
regulation of molecular function GO:0065009 398 0.012
embryonic pattern specification GO:0009880 1 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
positive regulation of signaling GO:0023056 270 0.012
eye morphogenesis GO:0048592 4 0.012
negative regulation of cell communication GO:0010648 158 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
epithelium development GO:0060429 96 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
regulation of hormone levels GO:0010817 187 0.012
negative regulation of developmental process GO:0051093 125 0.012
response to radiation GO:0009314 137 0.012
negative regulation of metabolic process GO:0009892 331 0.012
cardiovascular system development GO:0072358 134 0.012
regulation of neuron differentiation GO:0045664 208 0.012
cellular response to biotic stimulus GO:0071216 59 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
developmental process involved in reproduction GO:0003006 159 0.011
male gamete generation GO:0048232 99 0.011
heterocycle catabolic process GO:0046700 167 0.011
regulation of secretion GO:0051046 224 0.011
tissue development GO:0009888 252 0.011
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.011
vesicle mediated transport GO:0016192 181 0.011
response to ketone GO:1901654 182 0.011
multi multicellular organism process GO:0044706 138 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
secretion GO:0046903 307 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
regulation of phosphate metabolic process GO:0019220 349 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
protein transport GO:0015031 132 0.011
response to organophosphorus GO:0046683 102 0.011
blood circulation GO:0008015 183 0.011
embryonic axis specification GO:0000578 1 0.011
catabolic process GO:0009056 351 0.011
spermatogenesis GO:0007283 99 0.011
regulation of response to external stimulus GO:0032101 106 0.011
protein phosphorylation GO:0006468 345 0.011
sequestering of calcium ion GO:0051208 8 0.011
anterior posterior pattern specification GO:0009952 1 0.011
signal release GO:0023061 145 0.011
single organism catabolic process GO:0044712 283 0.011
anion transmembrane transport GO:0098656 77 0.011
carbohydrate derivative metabolic process GO:1901135 346 0.010
localization of cell GO:0051674 202 0.010
cell projection morphogenesis GO:0048858 123 0.010
negative regulation of cellular metabolic process GO:0031324 281 0.010
response to ammonium ion GO:0060359 71 0.010
positive regulation of cell development GO:0010720 176 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
epithelial cell differentiation GO:0030855 71 0.010
cellular response to oxidative stress GO:0034599 76 0.010
ras protein signal transduction GO:0007265 29 0.010
cellular macromolecule localization GO:0070727 122 0.010
regulation of phosphorus metabolic process GO:0051174 349 0.010
cell cell signaling GO:0007267 335 0.010
cation transport GO:0006812 382 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
biological adhesion GO:0022610 110 0.010
single organism behavior GO:0044708 130 0.010
negative regulation of nucleic acid templated transcription GO:1903507 117 0.010
regulation of tube size GO:0035150 89 0.010
negative regulation of macromolecule metabolic process GO:0010605 260 0.010

Pmel disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.037
retinal disease DOID:5679 0 0.020
sensory system disease DOID:0050155 0 0.020
eye and adnexa disease DOID:1492 0 0.020
eye disease DOID:5614 0 0.020
retinal degeneration DOID:8466 0 0.019