Rattus norvegicus

70 known processes

Fbxw8

F-box and WD repeat domain containing 8

Fbxw8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.096
organic acid metabolic process GO:0006082 292 0.085
carboxylic acid metabolic process GO:0019752 289 0.083
neuron development GO:0048666 286 0.070
intracellular signal transduction GO:0035556 314 0.064
regulation of neuron differentiation GO:0045664 208 0.059
regulation of cell development GO:0060284 263 0.058
regulation of neurogenesis GO:0050767 247 0.056
cell morphogenesis involved in differentiation GO:0000904 119 0.056
cell projection organization GO:0030030 302 0.055
neuron differentiation GO:0030182 368 0.050
cellular amino acid metabolic process GO:0006520 107 0.049
rna metabolic process GO:0016070 406 0.046
cellular component morphogenesis GO:0032989 155 0.045
regulation of cell differentiation GO:0045595 320 0.043
regulation of multicellular organismal development GO:2000026 376 0.041
amine metabolic process GO:0009308 38 0.040
ion transmembrane transport GO:0034220 365 0.039
regulation of nervous system development GO:0051960 264 0.037
lipid metabolic process GO:0006629 283 0.036
cellular ketone metabolic process GO:0042180 51 0.034
oxidation reduction process GO:0055114 304 0.034
positive regulation of multicellular organismal process GO:0051240 387 0.033
regulation of cellular ketone metabolic process GO:0010565 27 0.033
positive regulation of developmental process GO:0051094 283 0.032
neuron projection development GO:0031175 273 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.031
protein complex biogenesis GO:0070271 263 0.030
cellular amine metabolic process GO:0044106 38 0.030
single organism biosynthetic process GO:0044711 342 0.030
organic substance catabolic process GO:1901575 316 0.030
anatomical structure morphogenesis GO:0009653 298 0.029
cellular component biogenesis GO:0044085 368 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
regulation of anatomical structure morphogenesis GO:0022603 141 0.027
cell morphogenesis GO:0000902 142 0.027
regulation of cellular component organization GO:0051128 368 0.027
cell projection morphogenesis GO:0048858 123 0.027
nucleic acid templated transcription GO:0097659 379 0.026
rna biosynthetic process GO:0032774 380 0.026
cellular catabolic process GO:0044248 295 0.026
regulation of cell projection organization GO:0031344 175 0.026
macromolecular complex subunit organization GO:0043933 339 0.025
homeostatic process GO:0042592 331 0.025
transmembrane transport GO:0055085 412 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
response to peptide GO:1901652 292 0.025
cellular component assembly GO:0022607 360 0.025
behavior GO:0007610 205 0.024
chemical homeostasis GO:0048878 292 0.024
inorganic cation transmembrane transport GO:0098662 202 0.024
protein complex assembly GO:0006461 263 0.023
positive regulation of neurogenesis GO:0050769 165 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.022
response to ethanol GO:0045471 162 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
protein phosphorylation GO:0006468 345 0.022
neuron projection morphogenesis GO:0048812 122 0.022
positive regulation of cell development GO:0010720 176 0.021
reproduction GO:0000003 245 0.021
response to carbohydrate GO:0009743 183 0.021
regulation of neuron projection development GO:0010975 161 0.021
tissue development GO:0009888 252 0.021
positive regulation of neuron differentiation GO:0045666 126 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
regulation of cell proliferation GO:0042127 359 0.020
positive regulation of nervous system development GO:0051962 178 0.020
response to oxygen levels GO:0070482 265 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
transcription from rna polymerase ii promoter GO:0006366 252 0.020
response to growth factor GO:0070848 189 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
regulation of phosphate metabolic process GO:0019220 349 0.020
negative regulation of metabolic process GO:0009892 331 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.020
positive regulation of cellular component organization GO:0051130 200 0.019
regulation of protein metabolic process GO:0051246 289 0.019
macromolecule localization GO:0033036 252 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
cell part morphogenesis GO:0032990 123 0.019
ras protein signal transduction GO:0007265 29 0.019
secretion GO:0046903 307 0.019
single organism behavior GO:0044708 130 0.019
cellular lipid metabolic process GO:0044255 208 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
vesicle mediated transport GO:0016192 181 0.019
regulation of signal transduction GO:0009966 318 0.019
brain development GO:0007420 247 0.019
transcription dna templated GO:0006351 377 0.019
synaptic transmission GO:0007268 235 0.019
eye morphogenesis GO:0048592 4 0.018
head development GO:0060322 247 0.018
anterior posterior pattern specification GO:0009952 1 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
growth GO:0040007 165 0.018
regulation of secretion by cell GO:1903530 208 0.018
organophosphate metabolic process GO:0019637 370 0.018
protein complex subunit organization GO:0071822 302 0.018
protein localization GO:0008104 191 0.018
cation transport GO:0006812 382 0.018
central nervous system development GO:0007417 311 0.018
positive regulation of signaling GO:0023056 270 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
response to extracellular stimulus GO:0009991 380 0.018
regulation of rna metabolic process GO:0051252 391 0.017
neurological system process GO:0050877 219 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
response to monosaccharide GO:0034284 159 0.017
gland development GO:0048732 155 0.017
lipid biosynthetic process GO:0008610 128 0.017
response to amino acid GO:0043200 75 0.017
regulation of nucleic acid templated transcription GO:1903506 380 0.017
response to peptide hormone GO:0043434 278 0.017
cellular response to stress GO:0033554 269 0.017
organelle organization GO:0006996 266 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.016
response to acid chemical GO:0001101 222 0.016
regulation of molecular function GO:0065009 398 0.016
negative regulation of cell differentiation GO:0045596 99 0.016
positive regulation of gene expression GO:0010628 244 0.016
regulation of transcription dna templated GO:0006355 374 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
response to nutrient GO:0007584 248 0.016
gastrulation GO:0007369 2 0.016
cation homeostasis GO:0055080 195 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
response to decreased oxygen levels GO:0036293 237 0.016
cellular response to endogenous stimulus GO:0071495 377 0.016
response to alkaloid GO:0043279 132 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
cellular ion homeostasis GO:0006873 184 0.016
regulation of cellular localization GO:0060341 263 0.016
catabolic process GO:0009056 351 0.016
regulation of catalytic activity GO:0050790 304 0.016
response to radiation GO:0009314 137 0.016
negative regulation of transport GO:0051051 136 0.016
cellular homeostasis GO:0019725 252 0.016
macromolecular complex assembly GO:0065003 273 0.015
protein oligomerization GO:0051259 191 0.015
axon development GO:0061564 96 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
regulation of apoptotic process GO:0042981 335 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
cation transmembrane transport GO:0098655 263 0.015
secretion by cell GO:0032940 248 0.015
positive regulation of signal transduction GO:0009967 175 0.015
response to nutrient levels GO:0031667 370 0.015
response to hypoxia GO:0001666 231 0.015
purine containing compound metabolic process GO:0072521 253 0.015
regulation of protein modification process GO:0031399 194 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
negative regulation of cell development GO:0010721 82 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
cell cell signaling GO:0007267 335 0.015
single organism carbohydrate metabolic process GO:0044723 118 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
carbohydrate metabolic process GO:0005975 130 0.015
ion homeostasis GO:0050801 212 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
cellular chemical homeostasis GO:0055082 247 0.014
negative regulation of cell communication GO:0010648 158 0.014
metal ion transport GO:0030001 289 0.014
single organism catabolic process GO:0044712 283 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
regulation of membrane potential GO:0042391 110 0.014
monovalent inorganic cation transport GO:0015672 172 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
cellular response to oxygen containing compound GO:1901701 386 0.014
axis specification GO:0009798 4 0.014
blood circulation GO:0008015 183 0.014
embryonic pattern specification GO:0009880 1 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
single organism reproductive process GO:0044702 297 0.014
response to external biotic stimulus GO:0043207 221 0.014
response to hexose GO:0009746 144 0.014
heterocycle catabolic process GO:0046700 167 0.014
nitrogen compound transport GO:0071705 229 0.014
lipid storage GO:0019915 1 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
response to estrogen GO:0043627 232 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
cognition GO:0050890 92 0.013
negative regulation of cell death GO:0060548 229 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
jak stat cascade GO:0007259 26 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
hair cycle GO:0042633 3 0.013
cytoskeleton dependent cytokinesis GO:0061640 2 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
response to glucose GO:0009749 136 0.013
multi organism reproductive process GO:0044703 262 0.013
circulatory system development GO:0072359 134 0.013
blood vessel development GO:0001568 69 0.013
dendrite development GO:0016358 72 0.013
metal ion homeostasis GO:0055065 186 0.013
cardiovascular system development GO:0072358 134 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
motor neuron axon guidance GO:0008045 1 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
regulation of neuron death GO:1901214 115 0.013
multicellular organism reproduction GO:0032504 233 0.013
regulation of growth GO:0040008 105 0.013
multicellular organism growth GO:0035264 1 0.013
regulation of secretion GO:0051046 224 0.012
female pregnancy GO:0007565 122 0.012
positive regulation of molecular function GO:0044093 230 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.012
response to inorganic substance GO:0010035 377 0.012
chromosome segregation GO:0007059 2 0.012
regulation of phosphorylation GO:0042325 248 0.012
regulation of hormone levels GO:0010817 187 0.012
proteolysis GO:0006508 175 0.012
fatty acid metabolic process GO:0006631 99 0.012
regulation of programmed cell death GO:0043067 341 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
regulation of phosphorus metabolic process GO:0051174 349 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
cell growth GO:0016049 104 0.012
endomembrane system organization GO:0010256 48 0.012
mesoderm development GO:0007498 2 0.012
positive regulation of cell death GO:0010942 184 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
salivary gland development GO:0007431 3 0.012
cellular response to peptide GO:1901653 133 0.012
organophosphate catabolic process GO:0046434 148 0.012
liver development GO:0001889 90 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
anion transport GO:0006820 178 0.012
reproductive structure development GO:0048608 128 0.012
protein transport GO:0015031 132 0.011
positive regulation of protein modification process GO:0031401 142 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
regulation of cellular protein metabolic process GO:0032268 267 0.011
response to estradiol GO:0032355 164 0.011
cellular component movement GO:0006928 248 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
reproductive process GO:0022414 372 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
response to oxidative stress GO:0006979 186 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
camera type eye morphogenesis GO:0048593 2 0.011
response to biotic stimulus GO:0009607 226 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
aging GO:0007568 241 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
single organism intracellular transport GO:1902582 166 0.011
response to cytokine GO:0034097 215 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
regulation of dendrite morphogenesis GO:0048814 33 0.011
negative regulation of nervous system development GO:0051961 79 0.011
cytoplasmic transport GO:0016482 115 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
spindle organization GO:0007051 2 0.011
apoptotic process GO:0006915 381 0.011
vasculature development GO:0001944 70 0.011
cellular cation homeostasis GO:0030003 180 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
negative regulation of signaling GO:0023057 157 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
negative regulation of programmed cell death GO:0043069 183 0.010
nucleoside metabolic process GO:0009116 179 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
negative regulation of rna metabolic process GO:0051253 123 0.010
rho protein signal transduction GO:0007266 11 0.010
molting cycle process GO:0022404 2 0.010
tube development GO:0035295 89 0.010
organic acid transport GO:0015849 116 0.010
hepaticobiliary system development GO:0061008 90 0.010
nucleotide metabolic process GO:0009117 279 0.010
negative regulation of molecular function GO:0044092 133 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
single organism cellular localization GO:1902580 102 0.010

Fbxw8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
musculoskeletal system disease DOID:17 0 0.023
sensory system disease DOID:0050155 0 0.015
central nervous system disease DOID:331 0 0.014