Rattus norvegicus

102 known processes

Pnmt

phenylethanolamine-N-methyltransferase

Pnmt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle contraction GO:0006936 88 0.448
cation transmembrane transport GO:0098655 263 0.339
transmembrane transport GO:0055085 412 0.302
regulation of muscle contraction GO:0006937 53 0.240
inorganic ion transmembrane transport GO:0098660 229 0.205
response to oxygen levels GO:0070482 265 0.193
ion transmembrane transport GO:0034220 365 0.191
rhythmic process GO:0048511 156 0.184
regulation of membrane potential GO:0042391 110 0.171
regulation of amine transport GO:0051952 54 0.168
anion transmembrane transport GO:0098656 77 0.167
feeding behavior GO:0007631 53 0.146
circulatory system process GO:0003013 183 0.146
protein complex subunit organization GO:0071822 302 0.145
nitrogen compound transport GO:0071705 229 0.145
protein oligomerization GO:0051259 191 0.144
blood circulation GO:0008015 183 0.142
g protein coupled receptor signaling pathway GO:0007186 242 0.138
response to decreased oxygen levels GO:0036293 237 0.137
positive regulation of multicellular organismal process GO:0051240 387 0.128
organonitrogen compound biosynthetic process GO:1901566 167 0.121
neurological system process GO:0050877 219 0.117
positive regulation of biosynthetic process GO:0009891 319 0.115
protein complex biogenesis GO:0070271 263 0.110
heart process GO:0003015 57 0.104
muscle system process GO:0003012 115 0.103
protein phosphorylation GO:0006468 345 0.100
catecholamine transport GO:0051937 37 0.100
response to estrogen GO:0043627 232 0.099
regulation of catalytic activity GO:0050790 304 0.095
striated muscle contraction GO:0006941 44 0.094
cellular amino acid metabolic process GO:0006520 107 0.091
protein heterooligomerization GO:0051291 89 0.088
response to metal ion GO:0010038 253 0.087
regulation of muscle system process GO:0090257 79 0.087
cellular response to nitrogen compound GO:1901699 210 0.086
regulation of system process GO:0044057 208 0.086
response to inorganic substance GO:0010035 377 0.085
regulation of blood circulation GO:1903522 110 0.084
peptidyl amino acid modification GO:0018193 126 0.084
cellular component assembly GO:0022607 360 0.084
homeostatic process GO:0042592 331 0.081
cellular ketone metabolic process GO:0042180 51 0.081
catabolic process GO:0009056 351 0.080
regulation of phosphate metabolic process GO:0019220 349 0.077
protein complex assembly GO:0006461 263 0.076
carbohydrate derivative metabolic process GO:1901135 346 0.076
cellular catabolic process GO:0044248 295 0.075
regulation of heart contraction GO:0008016 48 0.074
cellular potassium ion transport GO:0071804 72 0.074
catecholamine secretion GO:0050432 33 0.073
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 2 0.070
intracellular signal transduction GO:0035556 314 0.070
organic acid metabolic process GO:0006082 292 0.070
macromolecular complex assembly GO:0065003 273 0.069
macromolecular complex subunit organization GO:0043933 339 0.069
inorganic cation transmembrane transport GO:0098662 202 0.068
heart contraction GO:0060047 57 0.067
cellular response to endogenous stimulus GO:0071495 377 0.066
reproductive process GO:0022414 372 0.066
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.065
positive regulation of molecular function GO:0044093 230 0.065
regulation of cellular amine metabolic process GO:0033238 8 0.063
monovalent inorganic cation transport GO:0015672 172 0.061
organic hydroxy compound transport GO:0015850 77 0.061
response to oxidative stress GO:0006979 186 0.061
response to carbohydrate GO:0009743 183 0.061
cellular response to organonitrogen compound GO:0071417 197 0.060
regulation of cellular amino acid metabolic process GO:0006521 2 0.060
nucleotide metabolic process GO:0009117 279 0.060
response to insulin GO:0032868 133 0.058
regulation of multicellular organismal development GO:2000026 376 0.057
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.057
regulation of transporter activity GO:0032409 50 0.056
purine ribonucleotide metabolic process GO:0009150 227 0.055
organic substance catabolic process GO:1901575 316 0.055
actin filament based process GO:0030029 86 0.055
ribonucleotide metabolic process GO:0009259 231 0.054
response to toxic substance GO:0009636 133 0.053
cation transport GO:0006812 382 0.052
nucleoside phosphate metabolic process GO:0006753 283 0.052
positive regulation of long term synaptic potentiation GO:1900273 4 0.052
positive regulation of phosphate metabolic process GO:0045937 262 0.051
positive regulation of cellular biosynthetic process GO:0031328 295 0.050
regulation of phosphorus metabolic process GO:0051174 349 0.050
potassium ion transmembrane transport GO:0071805 71 0.050
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.049
regulation of phosphorylation GO:0042325 248 0.049
synaptic transmission gabaergic GO:0051932 22 0.049
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.048
cellular amine metabolic process GO:0044106 38 0.048
negative regulation of multicellular organismal process GO:0051241 203 0.048
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.047
programmed cell death GO:0012501 392 0.047
action potential GO:0001508 54 0.047
regulation of tube size GO:0035150 89 0.045
purine nucleotide metabolic process GO:0006163 229 0.043
cytoskeleton organization GO:0007010 111 0.043
protein homooligomerization GO:0051260 91 0.042
response to cocaine GO:0042220 39 0.042
regulation of catecholamine secretion GO:0050433 32 0.042
behavior GO:0007610 205 0.042
positive regulation of cellular amine metabolic process GO:0033240 3 0.041
regulation of molecular function GO:0065009 398 0.040
neuron neuron synaptic transmission GO:0007270 60 0.040
regulation of blood vessel size GO:0050880 89 0.040
single organism catabolic process GO:0044712 283 0.040
reproduction GO:0000003 245 0.040
nucleobase containing small molecule metabolic process GO:0055086 316 0.039
negative regulation of molecular function GO:0044092 133 0.039
response to histamine GO:0034776 3 0.038
regulation of cellular ketone metabolic process GO:0010565 27 0.037
carbohydrate derivative biosynthetic process GO:1901137 124 0.037
cellular response to peptide GO:1901653 133 0.036
apoptotic process GO:0006915 381 0.036
cellular response to hormone stimulus GO:0032870 247 0.036
cellular response to organic cyclic compound GO:0071407 202 0.036
positive regulation of rna biosynthetic process GO:1902680 197 0.036
positive regulation of cellular component organization GO:0051130 200 0.035
sensory perception GO:0007600 101 0.035
cellular component movement GO:0006928 248 0.034
regulation of striated muscle contraction GO:0006942 21 0.034
actin mediated cell contraction GO:0070252 12 0.033
monoamine transport GO:0015844 43 0.033
oxoacid metabolic process GO:0043436 290 0.033
organophosphate metabolic process GO:0019637 370 0.033
single organism organelle organization GO:1902589 180 0.033
regulation of organelle organization GO:0033043 80 0.032
organelle organization GO:0006996 266 0.032
regulation of ion transmembrane transport GO:0034765 121 0.032
regulation of smooth muscle contraction GO:0006940 29 0.032
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.032
multi organism reproductive process GO:0044703 262 0.032
regulation of hormone levels GO:0010817 187 0.032
cardiac muscle contraction GO:0060048 27 0.032
central nervous system development GO:0007417 311 0.031
positive regulation of blood circulation GO:1903524 65 0.031
cellular response to histamine GO:0071420 3 0.031
regulation of ion transport GO:0043269 245 0.031
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.030
rhythmic behavior GO:0007622 24 0.030
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.030
regulation of circadian sleep wake cycle GO:0042749 18 0.030
cell cell signaling GO:0007267 335 0.030
regulation of protein processing GO:0070613 50 0.030
dopamine transport GO:0015872 18 0.029
ribose phosphate biosynthetic process GO:0046390 87 0.028
positive regulation of brown fat cell proliferation GO:0070349 1 0.028
ovulation cycle GO:0042698 67 0.028
actin cytoskeleton organization GO:0030036 73 0.028
circadian rhythm GO:0007623 88 0.028
multicellular organismal reproductive process GO:0048609 233 0.028
vasoconstriction GO:0042310 54 0.026
cellular macromolecule localization GO:0070727 122 0.026
regulation of anatomical structure size GO:0090066 135 0.026
purine containing compound metabolic process GO:0072521 253 0.026
organic cyclic compound catabolic process GO:1901361 175 0.026
regulation of secretion by cell GO:1903530 208 0.025
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.025
hormone secretion GO:0046879 115 0.025
regulation of cellular component organization GO:0051128 368 0.025
amine metabolic process GO:0009308 38 0.025
growth GO:0040007 165 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
regulation of cardiac muscle contraction GO:0055117 17 0.025
regulation of protein modification process GO:0031399 194 0.025
regulation of programmed cell death GO:0043067 341 0.025
brain development GO:0007420 247 0.025
response to peptide GO:1901652 292 0.025
regulation of cellular protein metabolic process GO:0032268 267 0.024
cellular response to oxygen containing compound GO:1901701 386 0.024
response to ketone GO:1901654 182 0.024
aromatic compound catabolic process GO:0019439 168 0.024
regulation of dopamine secretion GO:0014059 15 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
regulation of transmembrane transport GO:0034762 122 0.024
secretion by cell GO:0032940 248 0.024
response to bacterium GO:0009617 200 0.024
positive regulation of synaptic transmission GO:0050806 62 0.023
regulation of blood pressure GO:0008217 83 0.023
synaptic transmission glycinergic GO:0060012 2 0.023
single organism biosynthetic process GO:0044711 342 0.023
regulation of cellular localization GO:0060341 263 0.023
actin filament based movement GO:0030048 16 0.023
epithelium development GO:0060429 96 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
cell motility GO:0048870 202 0.022
positive regulation of transcription dna templated GO:0045893 197 0.022
regulation of peptide transport GO:0090087 87 0.022
regulation of nucleic acid templated transcription GO:1903506 380 0.022
response to estradiol GO:0032355 164 0.022
carbohydrate derivative catabolic process GO:1901136 147 0.022
nucleoside monophosphate metabolic process GO:0009123 93 0.021
regulation of smooth muscle cell proliferation GO:0048660 75 0.021
cyclic nucleotide metabolic process GO:0009187 80 0.021
positive regulation of protein transport GO:0051222 41 0.021
regulation of synaptic transmission GO:0050804 141 0.021
synaptic transmission GO:0007268 235 0.021
positive regulation of programmed cell death GO:0043068 157 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
regulation of hydrolase activity GO:0051336 143 0.021
response to radiation GO:0009314 137 0.021
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.021
cardiovascular system development GO:0072358 134 0.021
purine ribonucleotide catabolic process GO:0009154 136 0.021
response to reactive oxygen species GO:0000302 120 0.021
purine nucleoside catabolic process GO:0006152 124 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
response to ethanol GO:0045471 162 0.020
response to glucose GO:0009749 136 0.020
positive regulation of cell death GO:0010942 184 0.020
cell cycle GO:0007049 101 0.020
regulation of cell cycle GO:0051726 73 0.020
positive regulation of renin secretion into blood stream GO:1900135 1 0.020
regeneration GO:0031099 163 0.020
cellular response to stress GO:0033554 269 0.020
chemical homeostasis GO:0048878 292 0.020
negative regulation of cell death GO:0060548 229 0.020
response to monosaccharide GO:0034284 159 0.020
multicellular organism reproduction GO:0032504 233 0.020
negative regulation of circadian sleep wake cycle sleep GO:0042321 5 0.019
response to ammonium ion GO:0060359 71 0.019
cellular component biogenesis GO:0044085 368 0.019
defense response GO:0006952 194 0.019
positive regulation of gene expression GO:0010628 244 0.019
positive regulation of hormone secretion GO:0046887 65 0.019
immune response GO:0006955 104 0.019
response to extracellular stimulus GO:0009991 380 0.019
ribonucleotide biosynthetic process GO:0009260 85 0.019
maintenance of location GO:0051235 17 0.019
organ growth GO:0035265 24 0.019
regulation of signal transduction GO:0009966 318 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
amide transport GO:0042886 105 0.018
amino acid transport GO:0006865 70 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
purine containing compound catabolic process GO:0072523 138 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
aging GO:0007568 241 0.018
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 24 0.018
amine transport GO:0015837 57 0.018
purine ribonucleotide biosynthetic process GO:0009152 81 0.018
heterocycle catabolic process GO:0046700 167 0.017
peptide hormone secretion GO:0030072 84 0.017
sleep GO:0030431 30 0.017
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.017
smooth muscle cell proliferation GO:0048659 77 0.017
regulation of metal ion transport GO:0010959 118 0.017
carbohydrate metabolic process GO:0005975 130 0.017
regulation of apoptotic process GO:0042981 335 0.017
regulation of homeostatic process GO:0032844 101 0.017
regulation of vasoconstriction GO:0019229 44 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
response to external biotic stimulus GO:0043207 221 0.016
cyclic purine nucleotide metabolic process GO:0052652 62 0.016
positive regulation of developmental process GO:0051094 283 0.016
regulation of neuron apoptotic process GO:0043523 83 0.016
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
positive regulation of peptide secretion GO:0002793 52 0.016
multicellular organismal movement GO:0050879 17 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
angiogenesis involved in coronary vascular morphogenesis GO:0060978 3 0.016
nucleoside phosphate biosynthetic process GO:1901293 102 0.016
peptidyl tyrosine modification GO:0018212 72 0.016
regulation of actin filament based process GO:0032970 42 0.016
purine nucleotide biosynthetic process GO:0006164 83 0.016
muscle cell differentiation GO:0042692 52 0.016
oxidation reduction process GO:0055114 304 0.016
cellular protein localization GO:0034613 122 0.015
inflammatory response GO:0006954 150 0.015
positive regulation of transport GO:0051050 245 0.015
epithelial cell differentiation GO:0030855 71 0.015
purine nucleoside monophosphate metabolic process GO:0009126 84 0.015
developmental growth GO:0048589 100 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
negative regulation of phosphate metabolic process GO:0045936 80 0.015
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.015
response to biotic stimulus GO:0009607 226 0.015
mapk cascade GO:0000165 140 0.015
regulation of purine nucleotide metabolic process GO:1900542 115 0.015
regulation of cell growth GO:0001558 85 0.015
locomotion GO:0040011 237 0.015
membrane hyperpolarization GO:0060081 11 0.015
single organism carbohydrate metabolic process GO:0044723 118 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
regulation of synaptic plasticity GO:0048167 70 0.015
negative regulation of response to stimulus GO:0048585 155 0.014
wound healing GO:0042060 122 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
cellular glucan metabolic process GO:0006073 23 0.014
negative regulation of protein maturation GO:1903318 47 0.014
purine containing compound biosynthetic process GO:0072522 85 0.014
cardiac muscle cell development GO:0055013 16 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
circulatory system development GO:0072359 134 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
purine nucleoside triphosphate catabolic process GO:0009146 122 0.014
response to acid chemical GO:0001101 222 0.014
neuronal action potential GO:0019228 35 0.013
positive regulation of the force of heart contraction by epinephrine GO:0003059 1 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
negative regulation of synaptic transmission glutamatergic GO:0051967 8 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
regulation of secretion GO:0051046 224 0.013
neuron development GO:0048666 286 0.013
gonad development GO:0008406 104 0.013
terpene metabolic process GO:0042214 1 0.013
signal release GO:0023061 145 0.013
negative regulation of secretion by cell GO:1903531 72 0.013
cell type specific apoptotic process GO:0097285 134 0.013
protein tetramerization GO:0051262 38 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
regulation of immune system process GO:0002682 123 0.013
regulation of feeding behavior GO:0060259 14 0.013
striated muscle tissue development GO:0014706 58 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
potassium ion transport GO:0006813 97 0.012
positive regulation of mitochondrion organization GO:0010822 4 0.012
tissue morphogenesis GO:0048729 22 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
inorganic anion transport GO:0015698 41 0.012
regulation of catabolic process GO:0009894 113 0.012
transmission of nerve impulse GO:0019226 42 0.012
regulation of camp metabolic process GO:0030814 43 0.012
eating behavior GO:0042755 21 0.012
organophosphate catabolic process GO:0046434 148 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.012
regulation of cell migration GO:0030334 128 0.012
apoptotic signaling pathway GO:0097190 27 0.012
regulation of growth GO:0040008 105 0.012
atp catabolic process GO:0006200 54 0.012
tissue development GO:0009888 252 0.012
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.012
circadian sleep wake cycle sleep GO:0050802 21 0.012
serotonin receptor signaling pathway GO:0007210 10 0.012
hormone mediated signaling pathway GO:0009755 23 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
cellular response to glucocorticoid stimulus GO:0071385 68 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
negative regulation of metabolic process GO:0009892 331 0.011
positive regulation of cell communication GO:0010647 271 0.011
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.011
hexose transport GO:0008645 29 0.011
development of primary sexual characteristics GO:0045137 107 0.011
skeletal muscle contraction GO:0003009 17 0.011
single organism cellular localization GO:1902580 102 0.011
protein localization GO:0008104 191 0.011
regulation of actin filament based movement GO:1903115 12 0.011
regulation of transmembrane transporter activity GO:0022898 49 0.011
negative regulation of circadian rhythm GO:0042754 5 0.011
gastrulation GO:0007369 2 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
negative regulation of transport GO:0051051 136 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
nucleotide catabolic process GO:0009166 139 0.011
regulation of sodium ion transport GO:0002028 21 0.011
sensory organ development GO:0007423 74 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
negative regulation of neuron death GO:1901215 69 0.011
sodium ion transmembrane transport GO:0035725 67 0.011
cellular component morphogenesis GO:0032989 155 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
sodium ion transport GO:0006814 82 0.011
intracellular protein transport GO:0006886 79 0.011
positive regulation of nucleotide metabolic process GO:0045981 91 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
regulation of hormone secretion GO:0046883 106 0.011
cell growth GO:0016049 104 0.011
establishment of protein localization GO:0045184 141 0.010
regulation of nervous system development GO:0051960 264 0.010
positive regulation of blood pressure by epinephrine norepinephrine GO:0003321 2 0.010
locomotory behavior GO:0007626 15 0.010
urinary bladder smooth muscle contraction GO:0014832 4 0.010
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.010
regulation of transcription dna templated GO:0006355 374 0.010
regulation of transferase activity GO:0051338 123 0.010
hormone metabolic process GO:0042445 69 0.010
renin secretion into blood stream GO:0002001 1 0.010
single organism intracellular transport GO:1902582 166 0.010
respiratory system process GO:0003016 3 0.010
transcription from rna polymerase ii promoter GO:0006366 252 0.010
regulation of cytoskeleton organization GO:0051493 49 0.010
organ regeneration GO:0031100 101 0.010
purine nucleotide catabolic process GO:0006195 136 0.010

Pnmt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
eye and adnexa disease DOID:1492 0 0.022
sensory system disease DOID:0050155 0 0.022
muscular disease DOID:0080000 0 0.014
musculoskeletal system disease DOID:17 0 0.014
central nervous system disease DOID:331 0 0.014
myopathy DOID:423 0 0.011
muscle tissue disease DOID:66 0 0.011
eye disease DOID:5614 0 0.011