Rattus norvegicus

0 known processes

Prl3d1

Prolactin family 3, subfamily d, member 1

(Aliases: Pl-I,Pl1,Csh1,Pl-Im,rPl-1,Rhco1)

Prl3d1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
reproductive process GO:0022414 372 0.439
Rat
neurological system process GO:0050877 219 0.395
regulation of neurogenesis GO:0050767 247 0.263
Rat
regulation of cell development GO:0060284 263 0.254
Rat
regulation of multicellular organismal development GO:2000026 376 0.220
Rat
cell projection organization GO:0030030 302 0.213
cellular component movement GO:0006928 248 0.201
response to bacterium GO:0009617 200 0.200
Rat
response to lipopolysaccharide GO:0032496 191 0.193
Rat
regulation of nervous system development GO:0051960 264 0.175
Rat
neuron death GO:0070997 127 0.173
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.163
Rat
regulation of cell differentiation GO:0045595 320 0.160
Rat
cellular response to endogenous stimulus GO:0071495 377 0.155
Rat
reproduction GO:0000003 245 0.126
Rat
response to molecule of bacterial origin GO:0002237 194 0.126
Rat
chemical homeostasis GO:0048878 292 0.125
regulation of nucleic acid templated transcription GO:1903506 380 0.122
positive regulation of nervous system development GO:0051962 178 0.119
Rat
multicellular organismal reproductive process GO:0048609 233 0.110
Rat
regulation of neuron death GO:1901214 115 0.106
Rat
negative regulation of cell death GO:0060548 229 0.105
Rat
anatomical structure morphogenesis GO:0009653 298 0.103
positive regulation of gene expression GO:0010628 244 0.102
regulation of programmed cell death GO:0043067 341 0.100
intracellular signal transduction GO:0035556 314 0.099
negative regulation of nucleic acid templated transcription GO:1903507 117 0.099
protein phosphorylation GO:0006468 345 0.098
Rat
positive regulation of cell development GO:0010720 176 0.096
Rat
muscle system process GO:0003012 115 0.095
ion homeostasis GO:0050801 212 0.093
epithelial cell proliferation GO:0050673 54 0.092
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.091
Rat
regulation of molecular function GO:0065009 398 0.090
Rat
regulation of transcription dna templated GO:0006355 374 0.089
regulation of cell proliferation GO:0042127 359 0.088
Rat
regulation of catalytic activity GO:0050790 304 0.087
Rat
neuron projection development GO:0031175 273 0.086
positive regulation of catalytic activity GO:0043085 184 0.084
Rat
response to nutrient GO:0007584 248 0.084
Rat
negative regulation of transcription dna templated GO:0045892 116 0.083
circulatory system development GO:0072359 134 0.082
locomotion GO:0040011 237 0.082
neuron differentiation GO:0030182 368 0.080
positive regulation of cellular biosynthetic process GO:0031328 295 0.080
Rat
response to extracellular stimulus GO:0009991 380 0.079
Rat
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.079
response to heat GO:0009408 60 0.078
positive regulation of protein modification process GO:0031401 142 0.078
Rat
multi multicellular organism process GO:0044706 138 0.077
Rat
regulation of blood vessel size GO:0050880 89 0.076
regulation of protein modification process GO:0031399 194 0.072
Rat
potassium ion transport GO:0006813 97 0.072
negative regulation of cellular biosynthetic process GO:0031327 161 0.071
negative regulation of neuron death GO:1901215 69 0.070
Rat
rhythmic process GO:0048511 156 0.070
Rat
growth GO:0040007 165 0.068
Rat
regulation of neuron projection development GO:0010975 161 0.067
transcription from rna polymerase ii promoter GO:0006366 252 0.067
positive regulation of programmed cell death GO:0043068 157 0.067
programmed cell death GO:0012501 392 0.066
response to temperature stimulus GO:0009266 94 0.065
negative regulation of cellular metabolic process GO:0031324 281 0.065
response to estrogen GO:0043627 232 0.065
Rat
positive regulation of neurogenesis GO:0050769 165 0.064
Rat
positive regulation of molecular function GO:0044093 230 0.064
Rat
aging GO:0007568 241 0.064
jak stat cascade GO:0007259 26 0.063
rna metabolic process GO:0016070 406 0.062
cellular response to oxygen containing compound GO:1901701 386 0.062
regulation of system process GO:0044057 208 0.060
regulation of rna biosynthetic process GO:2001141 381 0.059
apoptotic process GO:0006915 381 0.059
negative regulation of rna metabolic process GO:0051253 123 0.059
regulation of cell projection organization GO:0031344 175 0.059
homeostatic process GO:0042592 331 0.058
negative regulation of cell proliferation GO:0008285 119 0.056
single organism reproductive process GO:0044702 297 0.056
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.056
Rat
multicellular organism reproduction GO:0032504 233 0.054
Rat
response to biotic stimulus GO:0009607 226 0.052
Rat
transcription dna templated GO:0006351 377 0.052
positive regulation of biosynthetic process GO:0009891 319 0.052
Rat
central nervous system development GO:0007417 311 0.051
regulation of protein phosphorylation GO:0001932 183 0.051
Rat
heart morphogenesis GO:0003007 3 0.051
positive regulation of apoptotic process GO:0043065 154 0.051
regulation of transferase activity GO:0051338 123 0.051
Rat
cellular response to stress GO:0033554 269 0.050
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.049
response to retinoic acid GO:0032526 63 0.048
circadian rhythm GO:0007623 88 0.048
Rat
positive regulation of cell death GO:0010942 184 0.048
response to interleukin 1 GO:0070555 55 0.047
behavior GO:0007610 205 0.047
regulation of apoptotic process GO:0042981 335 0.047
response to other organism GO:0051707 220 0.047
Rat
cellular response to abiotic stimulus GO:0071214 85 0.047
cellular response to acid chemical GO:0071229 75 0.046
regulation of cellular component movement GO:0051270 150 0.046
cellular homeostasis GO:0019725 252 0.045
nucleic acid templated transcription GO:0097659 379 0.045
regulation of cellular ketone metabolic process GO:0010565 27 0.044
regulation of cellular component organization GO:0051128 368 0.044
response to hypoxia GO:0001666 231 0.044
heart contraction GO:0060047 57 0.044
cellular component biogenesis GO:0044085 368 0.044
multicellular organismal signaling GO:0035637 44 0.043
action potential GO:0001508 54 0.043
response to mechanical stimulus GO:0009612 134 0.043
metal ion homeostasis GO:0055065 186 0.041
positive regulation of protein metabolic process GO:0051247 178 0.041
Rat
regulation of protein kinase activity GO:0045859 105 0.040
Rat
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.040
regulation of anatomical structure size GO:0090066 135 0.040
striated muscle contraction GO:0006941 44 0.040
response to oxygen levels GO:0070482 265 0.040
cellular response to nitrogen compound GO:1901699 210 0.039
cellular response to cytokine stimulus GO:0071345 127 0.038
regulation of intracellular signal transduction GO:1902531 218 0.038
Rat
response to acid chemical GO:0001101 222 0.038
cellular ketone metabolic process GO:0042180 51 0.038
response to cytokine GO:0034097 215 0.038
Rat
regulation of rna metabolic process GO:0051252 391 0.038
cellular response to lipid GO:0071396 201 0.038
positive regulation of developmental process GO:0051094 283 0.037
Rat
negative regulation of rna biosynthetic process GO:1902679 118 0.037
positive regulation of nucleic acid templated transcription GO:1903508 197 0.037
vasculature development GO:0001944 70 0.037
regulation of blood circulation GO:1903522 110 0.037
regulation of lipid metabolic process GO:0019216 68 0.036
Rat
regulation of protein metabolic process GO:0051246 289 0.036
Rat
negative regulation of gene expression GO:0010629 199 0.036
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.035
tissue remodeling GO:0048771 40 0.035
vasoconstriction GO:0042310 54 0.035
negative regulation of metabolic process GO:0009892 331 0.035
cell migration GO:0016477 197 0.034
response to wounding GO:0009611 254 0.034
positive regulation of signal transduction GO:0009967 175 0.034
Rat
negative regulation of programmed cell death GO:0043069 183 0.034
response to decreased oxygen levels GO:0036293 237 0.034
positive regulation of rna biosynthetic process GO:1902680 197 0.034
regulation of phosphate metabolic process GO:0019220 349 0.034
Rat
macromolecular complex subunit organization GO:0043933 339 0.034
regulation of signal transduction GO:0009966 318 0.034
Rat
rna biosynthetic process GO:0032774 380 0.034
muscle contraction GO:0006936 88 0.034
single organism behavior GO:0044708 130 0.033
positive regulation of cellular component organization GO:0051130 200 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
negative regulation of vasculature development GO:1901343 11 0.032
response to nutrient levels GO:0031667 370 0.031
Rat
response to estradiol GO:0032355 164 0.031
Rat
tissue development GO:0009888 252 0.031
blood vessel morphogenesis GO:0048514 58 0.031
positive regulation of neuron projection development GO:0010976 99 0.030
sensory perception GO:0007600 101 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.029
blood circulation GO:0008015 183 0.029
negative regulation of apoptotic process GO:0043066 181 0.029
regulation of tube size GO:0035150 89 0.029
transmission of nerve impulse GO:0019226 42 0.029
regulation of anatomical structure morphogenesis GO:0022603 141 0.029
acute inflammatory response GO:0002526 58 0.028
divalent inorganic cation transport GO:0072511 134 0.028
negative regulation of protein metabolic process GO:0051248 114 0.028
multi organism reproductive process GO:0044703 262 0.028
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.028
response to external biotic stimulus GO:0043207 221 0.028
Rat
negative regulation of biosynthetic process GO:0009890 168 0.028
renal system development GO:0072001 67 0.027
cellular response to molecule of bacterial origin GO:0071219 56 0.027
skeletal muscle satellite cell proliferation GO:0014841 1 0.027
immune response GO:0006955 104 0.027
positive regulation of signaling GO:0023056 270 0.027
Rat
cytoskeleton organization GO:0007010 111 0.026
positive regulation of response to stimulus GO:0048584 285 0.026
Rat
cellular chemical homeostasis GO:0055082 247 0.026
negative regulation of multicellular organismal process GO:0051241 203 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.026
immune system process GO:0002376 204 0.026
divalent metal ion transport GO:0070838 132 0.026
vascular process in circulatory system GO:0003018 96 0.026
regulation of cellular protein metabolic process GO:0032268 267 0.026
Rat
cellular cation homeostasis GO:0030003 180 0.025
hormone biosynthetic process GO:0042446 25 0.025
Rat
protein oligomerization GO:0051259 191 0.025
response to alkaloid GO:0043279 132 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
Rat
positive regulation of cell proliferation GO:0008284 249 0.025
Rat
regulation of epithelial cell proliferation GO:0050678 49 0.025
Rat
defense response GO:0006952 194 0.024
regulation of vasculature development GO:1901342 44 0.024
cognition GO:0050890 92 0.024
cellular component morphogenesis GO:0032989 155 0.024
circulatory system process GO:0003013 183 0.024
organophosphate metabolic process GO:0019637 370 0.024
cell growth GO:0016049 104 0.024
neuronal action potential GO:0019228 35 0.024
response to vitamin GO:0033273 131 0.024
cell morphogenesis GO:0000902 142 0.023
regulation of growth GO:0040008 105 0.023
Rat
anatomical structure formation involved in morphogenesis GO:0048646 83 0.023
cell motility GO:0048870 202 0.023
cation transmembrane transport GO:0098655 263 0.023
positive regulation of rna metabolic process GO:0051254 203 0.023
protein complex subunit organization GO:0071822 302 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
positive regulation of transcription dna templated GO:0045893 197 0.022
regulation of renin secretion into blood stream GO:1900133 1 0.022
response to peptide hormone GO:0043434 278 0.022
Rat
purine ribonucleotide metabolic process GO:0009150 227 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
positive regulation of the force of heart contraction by epinephrine GO:0003059 1 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
regulation of neuron differentiation GO:0045664 208 0.021
sexual reproduction GO:0019953 148 0.021
regulation of angiogenesis GO:0045765 39 0.021
neuron development GO:0048666 286 0.021
response to oxidative stress GO:0006979 186 0.021
response to ketone GO:1901654 182 0.021
metal ion transport GO:0030001 289 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
cytokine production GO:0001816 61 0.021
positive regulation of growth GO:0045927 55 0.021
Rat
protein complex assembly GO:0006461 263 0.021
amine metabolic process GO:0009308 38 0.020
organophosphate catabolic process GO:0046434 148 0.020
regulation of cell growth GO:0001558 85 0.020
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.020
response to osmotic stress GO:0006970 42 0.020
cellular amino acid metabolic process GO:0006520 107 0.020
cellular ion homeostasis GO:0006873 184 0.020
c21 steroid hormone biosynthetic process GO:0006700 10 0.020
positive regulation of cell migration GO:0030335 96 0.020
calcium ion homeostasis GO:0055074 162 0.020
positive regulation of transferase activity GO:0051347 81 0.020
Rat
anterior posterior pattern specification GO:0009952 1 0.019
regulation of dendrite development GO:0050773 59 0.019
regulation of cell migration GO:0030334 128 0.019
regulation of jak stat cascade GO:0046425 21 0.019
Rat
cellular response to tumor necrosis factor GO:0071356 46 0.019
inflammatory response GO:0006954 150 0.019
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.019
cardiac muscle contraction GO:0060048 27 0.019
cell cell signaling GO:0007267 335 0.018
response to vitamin a GO:0033189 36 0.018
negative regulation of growth GO:0045926 37 0.018
regulation of platelet activation GO:0010543 2 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.018
wound healing GO:0042060 122 0.018
regulation of phosphorylation GO:0042325 248 0.018
Rat
organonitrogen compound catabolic process GO:1901565 179 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
regulation of kidney development GO:0090183 15 0.018
proteolysis GO:0006508 175 0.018
regulation of transporter activity GO:0032409 50 0.018
actin filament based process GO:0030029 86 0.018
reactive nitrogen species metabolic process GO:2001057 1 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
purine nucleoside triphosphate metabolic process GO:0009144 141 0.017
protein complex biogenesis GO:0070271 263 0.017
positive regulation of transport GO:0051050 245 0.017
blood vessel development GO:0001568 69 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
Rat
nucleoside metabolic process GO:0009116 179 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
regulation of neurological system process GO:0031644 43 0.016
negative regulation of developmental process GO:0051093 125 0.016
head development GO:0060322 247 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
regulation of response to external stimulus GO:0032101 106 0.016
regulation of cell motility GO:2000145 131 0.016
negative regulation of kidney development GO:0090185 2 0.016
response to electrical stimulus GO:0051602 56 0.016
cellular response to interleukin 1 GO:0071347 37 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.016
response to hyperoxia GO:0055093 45 0.016
muscle organ morphogenesis GO:0048644 1 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
Rat
regulation of metanephros development GO:0072215 4 0.015
cellular component assembly GO:0022607 360 0.015
epithelial cell differentiation GO:0030855 71 0.015
tube development GO:0035295 89 0.015
Rat
response to ionizing radiation GO:0010212 59 0.015
cellular response to lipopolysaccharide GO:0071222 55 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
n methyl d aspartate receptor clustering GO:0097114 2 0.015
response to increased oxygen levels GO:0036296 45 0.015
ras protein signal transduction GO:0007265 29 0.015
regulation of locomotion GO:0040012 148 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
Rat
renal system process GO:0003014 40 0.015
regulation of lipid biosynthetic process GO:0046890 38 0.015
Rat
multicellular organism growth GO:0035264 1 0.015
macromolecular complex assembly GO:0065003 273 0.015
saliva secretion GO:0046541 3 0.015
brain renin angiotensin system GO:0002035 3 0.014
cellular amine metabolic process GO:0044106 38 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
localization of cell GO:0051674 202 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
cellular response to external stimulus GO:0071496 118 0.014
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.014
response to peptide GO:1901652 292 0.014
Rat
positive regulation of cell communication GO:0010647 271 0.014
Rat
response to glucocorticoid GO:0051384 223 0.014
cation homeostasis GO:0055080 195 0.013
regulation of membrane potential GO:0042391 110 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
Rat
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.013
protein targeting GO:0006605 61 0.013
male gamete generation GO:0048232 99 0.013
cation transport GO:0006812 382 0.013
response to radiation GO:0009314 137 0.013
Rat
negative regulation of cell communication GO:0010648 158 0.013
response to insulin GO:0032868 133 0.013
epithelial cell differentiation involved in kidney development GO:0035850 3 0.013
protein transport GO:0015031 132 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
Rat
cell projection morphogenesis GO:0048858 123 0.013
negative regulation of phosphorus metabolic process GO:0010563 80 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
regulation of response to wounding GO:1903034 69 0.013
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
ribonucleoside monophosphate metabolic process GO:0009161 88 0.013
regulation of cytoskeleton organization GO:0051493 49 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
Rat
regulation of response to stress GO:0080134 126 0.013
glial cell differentiation GO:0010001 65 0.012
regulation of ion transport GO:0043269 245 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
mapk cascade GO:0000165 140 0.012
urinary bladder smooth muscle contraction GO:0014832 4 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
response to reactive oxygen species GO:0000302 120 0.012
response to growth factor GO:0070848 189 0.012
regulation of behavior GO:0050795 61 0.012
maintenance of location GO:0051235 17 0.012
eye development GO:0001654 50 0.012
artery smooth muscle contraction GO:0014824 4 0.012
positive regulation of lipid metabolic process GO:0045834 33 0.012
Rat
vasodilation GO:0042311 44 0.012
heart process GO:0003015 57 0.012
regulation of muscle system process GO:0090257 79 0.012
regulation of mapk cascade GO:0043408 116 0.012
mating GO:0007618 22 0.012
positive regulation of kinase activity GO:0033674 77 0.012
Rat
synaptic transmission GO:0007268 235 0.012
cellular catabolic process GO:0044248 295 0.011
regulation of striated muscle contraction GO:0006942 21 0.011
peptide biosynthetic process GO:0043043 3 0.011
negative regulation of nervous system development GO:0051961 79 0.011
regulation of neuronal synaptic plasticity GO:0048168 31 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
cell cycle process GO:0022402 57 0.011
sensory organ development GO:0007423 74 0.011
regulation of vasoconstriction GO:0019229 44 0.011
nucleotide metabolic process GO:0009117 279 0.011
cellular response to alcohol GO:0097306 87 0.011
cellular macromolecule localization GO:0070727 122 0.011
mesoderm development GO:0007498 2 0.011
gliogenesis GO:0042063 93 0.011
heart development GO:0007507 72 0.011
endocytosis GO:0006897 84 0.011
glucocorticoid biosynthetic process GO:0006704 5 0.011
regulation of satellite cell proliferation GO:0014842 1 0.011
l glutamate import GO:0051938 2 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
regulation of synaptic plasticity GO:0048167 70 0.011
secretion by cell GO:0032940 248 0.011
regulation of atp biosynthetic process GO:2001169 2 0.011
axis specification GO:0009798 4 0.011
cardiac muscle cell contraction GO:0086003 10 0.011
regulation of heart contraction GO:0008016 48 0.011
response to activity GO:0014823 73 0.011
purine containing compound metabolic process GO:0072521 253 0.011
dendrite development GO:0016358 72 0.011
cell part morphogenesis GO:0032990 123 0.011
neuromuscular process GO:0050905 2 0.010
cell differentiation involved in kidney development GO:0061005 4 0.010
regulation of cardiac muscle contraction GO:0055117 17 0.010
negative regulation of metanephros development GO:0072217 2 0.010
potassium ion homeostasis GO:0055075 2 0.010
regulation of neuron apoptotic process GO:0043523 83 0.010
regulation of vasodilation GO:0042312 36 0.010
endocrine system development GO:0035270 30 0.010
regulation of hydrolase activity GO:0051336 143 0.010
response to ethanol GO:0045471 162 0.010
Rat
synapse assembly GO:0007416 29 0.010

Prl3d1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
substance dependence DOID:9973 0 0.018
substance related disorder DOID:303 0 0.018
disease of mental health DOID:150 0 0.018
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
myopathy DOID:423 0 0.017
muscular disease DOID:0080000 0 0.017
musculoskeletal system disease DOID:17 0 0.017
muscle tissue disease DOID:66 0 0.017
sensory system disease DOID:0050155 0 0.014
long qt syndrome DOID:2843 0 0.011