Rattus norvegicus

136 known processes

Trpv4

transient receptor potential cation channel, subfamily V, member 4

(Aliases: Vroac,Otrpc4)

Trpv4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.100
oxoacid metabolic process GO:0043436 290 0.067
response to metal ion GO:0010038 253 0.061
regulation of secretion GO:0051046 224 0.060
Rat
response to oxygen levels GO:0070482 265 0.057
central nervous system development GO:0007417 311 0.057
organic acid metabolic process GO:0006082 292 0.054
positive regulation of cell death GO:0010942 184 0.053
Rat
homeostatic process GO:0042592 331 0.052
response to decreased oxygen levels GO:0036293 237 0.050
regulation of apoptotic process GO:0042981 335 0.048
Rat
head development GO:0060322 247 0.047
positive regulation of apoptotic process GO:0043065 154 0.046
Rat
neurological system process GO:0050877 219 0.045
cellular ion homeostasis GO:0006873 184 0.042
cation transport GO:0006812 382 0.038
divalent inorganic cation homeostasis GO:0072507 165 0.038
regulation of cellular ketone metabolic process GO:0010565 27 0.037
negative regulation of cellular metabolic process GO:0031324 281 0.036
aromatic compound catabolic process GO:0019439 168 0.035
brain development GO:0007420 247 0.035
lipid metabolic process GO:0006629 283 0.033
ribonucleoside metabolic process GO:0009119 174 0.032
single organism biosynthetic process GO:0044711 342 0.032
single organism catabolic process GO:0044712 283 0.032
cellular catabolic process GO:0044248 295 0.031
metal ion transport GO:0030001 289 0.031
gonad development GO:0008406 104 0.031
regulation of cellular protein metabolic process GO:0032268 267 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
Rat
negative regulation of signaling GO:0023057 157 0.030
regulation of hormone levels GO:0010817 187 0.029
Mouse
macromolecular complex assembly GO:0065003 273 0.029
rhythmic process GO:0048511 156 0.029
nucleoside phosphate metabolic process GO:0006753 283 0.028
growth GO:0040007 165 0.028
organophosphate metabolic process GO:0019637 370 0.028
proteolysis GO:0006508 175 0.027
development of primary sexual characteristics GO:0045137 107 0.027
monovalent inorganic cation transport GO:0015672 172 0.027
regulation of programmed cell death GO:0043067 341 0.026
Rat
organic cyclic compound catabolic process GO:1901361 175 0.026
response to nutrient levels GO:0031667 370 0.026
response to hypoxia GO:0001666 231 0.026
potassium ion transport GO:0006813 97 0.026
glycosyl compound metabolic process GO:1901657 182 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.025
Rat
transmembrane transport GO:0055085 412 0.025
intracellular signal transduction GO:0035556 314 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.025
monocarboxylic acid metabolic process GO:0032787 152 0.024
amine metabolic process GO:0009308 38 0.024
organic substance catabolic process GO:1901575 316 0.024
cation transmembrane transport GO:0098655 263 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
cellular amino acid metabolic process GO:0006520 107 0.024
reproductive structure development GO:0048608 128 0.024
heart morphogenesis GO:0003007 3 0.023
regulation of cell differentiation GO:0045595 320 0.023
single organism intracellular transport GO:1902582 166 0.023
Rat
protein complex assembly GO:0006461 263 0.023
nucleotide metabolic process GO:0009117 279 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.023
nucleoside metabolic process GO:0009116 179 0.022
cellular amine metabolic process GO:0044106 38 0.022
hormone metabolic process GO:0042445 69 0.022
response to peptide GO:1901652 292 0.022
Rat
cellular nitrogen compound catabolic process GO:0044270 163 0.022
cellular component biogenesis GO:0044085 368 0.022
organophosphate catabolic process GO:0046434 148 0.021
cellular response to cytokine stimulus GO:0071345 127 0.021
Rat
reproductive process GO:0022414 372 0.021
nucleotide catabolic process GO:0009166 139 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.020
detection of visible light GO:0009584 3 0.020
response to radiation GO:0009314 137 0.020
small gtpase mediated signal transduction GO:0007264 36 0.020
receptor metabolic process GO:0043112 18 0.020
reproductive system development GO:0061458 128 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
nucleic acid templated transcription GO:0097659 379 0.020
organic hydroxy compound metabolic process GO:1901615 115 0.020
organonitrogen compound biosynthetic process GO:1901566 167 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
cell growth GO:0016049 104 0.020
synaptic transmission GO:0007268 235 0.020
calcium ion transport GO:0006816 131 0.020
ion homeostasis GO:0050801 212 0.020
regulation of rna metabolic process GO:0051252 391 0.020
nucleobase containing compound catabolic process GO:0034655 152 0.020
organ regeneration GO:0031100 101 0.020
heterocycle catabolic process GO:0046700 167 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
cellular response to oxygen containing compound GO:1901701 386 0.019
Rat
secretion GO:0046903 307 0.019
Mouse Rat
response to transition metal nanoparticle GO:1990267 122 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.019
regulation of transcription dna templated GO:0006355 374 0.019
purine nucleoside catabolic process GO:0006152 124 0.019
cellular lipid metabolic process GO:0044255 208 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.019
single organism reproductive process GO:0044702 297 0.018
purine nucleoside metabolic process GO:0042278 169 0.018
organelle organization GO:0006996 266 0.018
ribonucleotide catabolic process GO:0009261 136 0.018
response to inorganic substance GO:0010035 377 0.018
regulation of protein metabolic process GO:0051246 289 0.018
cellular component assembly GO:0022607 360 0.018
receptor mediated endocytosis GO:0006898 42 0.018
regulation of secretion by cell GO:1903530 208 0.018
calcium ion homeostasis GO:0055074 162 0.018
regulation of system process GO:0044057 208 0.018
Rat
response to purine containing compound GO:0014074 126 0.018
Rat
cellular hormone metabolic process GO:0034754 49 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
regulation of signal transduction GO:0009966 318 0.018
negative regulation of metabolic process GO:0009892 331 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
regulation of hydrolase activity GO:0051336 143 0.017
vesicle mediated transport GO:0016192 181 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
negative regulation of transcription dna templated GO:0045892 116 0.017
protein homooligomerization GO:0051260 91 0.017
glycosyl compound catabolic process GO:1901658 126 0.017
purine containing compound metabolic process GO:0072521 253 0.017
rna metabolic process GO:0016070 406 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.017
small molecule biosynthetic process GO:0044283 124 0.016
apoptotic process GO:0006915 381 0.016
Rat
negative regulation of cell communication GO:0010648 158 0.016
reproduction GO:0000003 245 0.016
response to peptide hormone GO:0043434 278 0.016
Rat
divalent metal ion transport GO:0070838 132 0.016
negative regulation of cell death GO:0060548 229 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
regulation of molecular function GO:0065009 398 0.016
behavior GO:0007610 205 0.016
multi organism reproductive process GO:0044703 262 0.016
regulation of nucleotide catabolic process GO:0030811 65 0.016
sex differentiation GO:0007548 113 0.016
female gonad development GO:0008585 53 0.016
cellular ketone metabolic process GO:0042180 51 0.016
tissue development GO:0009888 252 0.016
inner ear morphogenesis GO:0042472 1 0.016
rna biosynthetic process GO:0032774 380 0.016
unsaturated fatty acid metabolic process GO:0033559 39 0.016
regulation of ion transport GO:0043269 245 0.016
Rat
ras protein signal transduction GO:0007265 29 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
Rat
purine nucleotide catabolic process GO:0006195 136 0.015
inorganic cation transmembrane transport GO:0098662 202 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
amino acid transmembrane transport GO:0003333 33 0.015
steroid metabolic process GO:0008202 73 0.015
gtp catabolic process GO:0006184 71 0.015
neuron fate commitment GO:0048663 4 0.015
response to nutrient GO:0007584 248 0.015
cellular component movement GO:0006928 248 0.015
cardiovascular system development GO:0072358 134 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
catabolic process GO:0009056 351 0.015
positive regulation of secretion by cell GO:1903532 128 0.015
regulation of cellular component organization GO:0051128 368 0.015
negative regulation of signal transduction GO:0009968 83 0.015
adult locomotory behavior GO:0008344 4 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.015
cation homeostasis GO:0055080 195 0.015
neuronal action potential GO:0019228 35 0.015
cellular response to tumor necrosis factor GO:0071356 46 0.015
Rat
sequestering of metal ion GO:0051238 9 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.014
positive regulation of molecular function GO:0044093 230 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
programmed cell death GO:0012501 392 0.014
Rat
chemosensory behavior GO:0007635 2 0.014
regulation of protein localization GO:0032880 81 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
lipid modification GO:0030258 52 0.014
ion transmembrane transport GO:0034220 365 0.014
developmental process involved in reproduction GO:0003006 159 0.014
heart development GO:0007507 72 0.014
regulation of cellular catabolic process GO:0031329 101 0.014
protein complex biogenesis GO:0070271 263 0.014
protein oligomerization GO:0051259 191 0.014
regulation of purine nucleotide catabolic process GO:0033121 65 0.014
regulation of rna biosynthetic process GO:2001141 381 0.014
cellular homeostasis GO:0019725 252 0.014
guanosine containing compound catabolic process GO:1901069 71 0.013
regulation of cellular localization GO:0060341 263 0.013
hormone transport GO:0009914 121 0.013
Mouse
cellular chemical homeostasis GO:0055082 247 0.013
intracellular transport GO:0046907 185 0.013
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
aging GO:0007568 241 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
Rat
locomotion GO:0040011 237 0.013
cardiac chamber development GO:0003205 1 0.013
negative regulation of molecular function GO:0044092 133 0.013
macromolecule localization GO:0033036 252 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
positive regulation of protein modification process GO:0031401 142 0.013
oxidation reduction process GO:0055114 304 0.013
dna metabolic process GO:0006259 96 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
Rat
purine nucleoside triphosphate catabolic process GO:0009146 122 0.013
carbohydrate derivative metabolic process GO:1901135 346 0.013
fatty acid metabolic process GO:0006631 99 0.012
protein phosphorylation GO:0006468 345 0.012
axis specification GO:0009798 4 0.012
organic hydroxy compound biosynthetic process GO:1901617 51 0.012
positive regulation of ion transport GO:0043270 94 0.012
Rat
eye morphogenesis GO:0048592 4 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
regulation of catalytic activity GO:0050790 304 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
anion transmembrane transport GO:0098656 77 0.012
Rat
negative regulation of response to stimulus GO:0048585 155 0.012
regulation of metal ion transport GO:0010959 118 0.012
Rat
smooth muscle cell apoptotic process GO:0034390 7 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
response to extracellular stimulus GO:0009991 380 0.012
regulation of nucleoside metabolic process GO:0009118 66 0.012
organic anion transport GO:0015711 132 0.012
Rat
regulation of cell growth GO:0001558 85 0.012
neuron death GO:0070997 127 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
positive regulation of secretion GO:0051047 140 0.012
Rat
regulation of multicellular organismal development GO:2000026 376 0.012
regulation of kinase activity GO:0043549 117 0.012
negative regulation of neuron differentiation GO:0045665 62 0.012
signal release GO:0023061 145 0.012
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
regulation of cell development GO:0060284 263 0.012
olfactory behavior GO:0042048 2 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
chemical homeostasis GO:0048878 292 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
lipid biosynthetic process GO:0008610 128 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
cofactor metabolic process GO:0051186 95 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
single organism behavior GO:0044708 130 0.011
biological adhesion GO:0022610 110 0.011
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.011
ovulation cycle GO:0042698 67 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
response to ethanol GO:0045471 162 0.011
sensory organ development GO:0007423 74 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
regulation of membrane potential GO:0042391 110 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
sensory perception of bitter taste GO:0050913 4 0.011
cytoplasmic transport GO:0016482 115 0.011
Rat
cellular metal ion homeostasis GO:0006875 172 0.011
positive regulation of cell communication GO:0010647 271 0.011
camera type eye development GO:0043010 48 0.011
alcohol metabolic process GO:0006066 77 0.011
sensory perception of light stimulus GO:0050953 3 0.011
regulation of growth GO:0040008 105 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
protein localization GO:0008104 191 0.011
cellular response to oxygen levels GO:0071453 60 0.011
secretion by cell GO:0032940 248 0.011
Mouse Rat
positive regulation of protein metabolic process GO:0051247 178 0.010
development of primary female sexual characteristics GO:0046545 56 0.010
gtp metabolic process GO:0046039 72 0.010
ovulation cycle process GO:0022602 50 0.010
regulation of transferase activity GO:0051338 123 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
rho protein signal transduction GO:0007266 11 0.010
multicellular organismal reproductive process GO:0048609 233 0.010
anatomical structure morphogenesis GO:0009653 298 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
regulation of cell projection organization GO:0031344 175 0.010
detection of stimulus GO:0051606 24 0.010
muscle tissue morphogenesis GO:0060415 1 0.010
positive regulation of gene expression GO:0010628 244 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
lens fiber cell differentiation GO:0070306 3 0.010
regulation of vesicle mediated transport GO:0060627 81 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
regulation of neuron death GO:1901214 115 0.010
positive regulation of catabolic process GO:0009896 78 0.010

Trpv4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
Human
nervous system disease DOID:863 0 0.040
Human
cardiovascular system disease DOID:1287 0 0.022
central nervous system disease DOID:331 0 0.015
sensory system disease DOID:0050155 0 0.015
heart disease DOID:114 0 0.011
musculoskeletal system disease DOID:17 0 0.011
Human