Rattus norvegicus

0 known processes

Pde6b

phosphodiesterase 6B, cGMP-specific, rod, beta

Pde6b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.098
anatomical structure morphogenesis GO:0009653 298 0.096
organ morphogenesis GO:0009887 75 0.095
tissue development GO:0009888 252 0.095
Rat
tongue morphogenesis GO:0043587 3 0.074
positive regulation of biosynthetic process GO:0009891 319 0.074
transcription dna templated GO:0006351 377 0.071
nucleic acid templated transcription GO:0097659 379 0.070
rna metabolic process GO:0016070 406 0.069
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.068
programmed cell death GO:0012501 392 0.062
Rat
rna biosynthetic process GO:0032774 380 0.058
response to oxygen levels GO:0070482 265 0.058
Rat
sensory organ development GO:0007423 74 0.056
head development GO:0060322 247 0.055
positive regulation of cellular biosynthetic process GO:0031328 295 0.054
transcription from rna polymerase ii promoter GO:0006366 252 0.052
regulation of rna metabolic process GO:0051252 391 0.050
regulation of nucleic acid templated transcription GO:1903506 380 0.050
positive regulation of transcription dna templated GO:0045893 197 0.047
regulation of apoptotic process GO:0042981 335 0.042
Rat
amine metabolic process GO:0009308 38 0.042
purine nucleotide metabolic process GO:0006163 229 0.040
Human Rat
response to radiation GO:0009314 137 0.040
positive regulation of multicellular organismal process GO:0051240 387 0.040
Rat
cell morphogenesis GO:0000902 142 0.040
reproductive process GO:0022414 372 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.036
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.036
carbohydrate derivative biosynthetic process GO:1901137 124 0.036
Rat
negative regulation of metabolic process GO:0009892 331 0.036
Rat
apoptotic process GO:0006915 381 0.035
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.035
Human Rat
reproductive structure development GO:0048608 128 0.035
eye morphogenesis GO:0048592 4 0.035
regulation of transcription dna templated GO:0006355 374 0.035
organophosphate metabolic process GO:0019637 370 0.035
Human Rat
regulation of rna biosynthetic process GO:2001141 381 0.035
reproduction GO:0000003 245 0.034
regulation of phosphorus metabolic process GO:0051174 349 0.033
Rat
single organism biosynthetic process GO:0044711 342 0.033
Rat
ion homeostasis GO:0050801 212 0.033
Human
nucleoside phosphate metabolic process GO:0006753 283 0.033
Human Rat
homeostatic process GO:0042592 331 0.032
Human
protein phosphorylation GO:0006468 345 0.032
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.032
nucleotide metabolic process GO:0009117 279 0.030
Human Rat
rhythmic process GO:0048511 156 0.029
cellular amine metabolic process GO:0044106 38 0.029
intracellular signal transduction GO:0035556 314 0.029
Rat
reproductive system development GO:0061458 128 0.029
regulation of nucleotide metabolic process GO:0006140 117 0.028
Rat
neuron differentiation GO:0030182 368 0.028
organophosphate biosynthetic process GO:0090407 143 0.028
Rat
positive regulation of apoptotic process GO:0043065 154 0.028
Rat
positive regulation of rna metabolic process GO:0051254 203 0.028
organic cyclic compound catabolic process GO:1901361 175 0.027
Rat
response to metal ion GO:0010038 253 0.027
regulation of cell development GO:0060284 263 0.027
positive regulation of gene expression GO:0010628 244 0.027
regulation of catalytic activity GO:0050790 304 0.027
anterior posterior pattern specification GO:0009952 1 0.026
response to hypoxia GO:0001666 231 0.026
Rat
cyclic purine nucleotide metabolic process GO:0052652 62 0.026
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.026
single organism reproductive process GO:0044702 297 0.026
regulation of programmed cell death GO:0043067 341 0.026
Rat
muscle cell proliferation GO:0033002 84 0.025
organonitrogen compound biosynthetic process GO:1901566 167 0.025
Rat
purine nucleoside metabolic process GO:0042278 169 0.025
Human
neuron projection development GO:0031175 273 0.025
cellular component biogenesis GO:0044085 368 0.025
purine containing compound metabolic process GO:0072521 253 0.025
Human Rat
developmental process involved in reproduction GO:0003006 159 0.024
regulation of phosphate metabolic process GO:0019220 349 0.024
Rat
cation transmembrane transport GO:0098655 263 0.024
multicellular organism reproduction GO:0032504 233 0.023
cellular amino acid metabolic process GO:0006520 107 0.023
regulation of phosphorylation GO:0042325 248 0.023
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.023
phototransduction visible light GO:0007603 2 0.023
positive regulation of developmental process GO:0051094 283 0.023
transmembrane transport GO:0055085 412 0.023
aging GO:0007568 241 0.023
dna metabolic process GO:0006259 96 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
positive regulation of phosphorylation GO:0042327 177 0.022
metal ion transport GO:0030001 289 0.022
central nervous system development GO:0007417 311 0.022
positive regulation of nucleic acid templated transcription GO:1903508 197 0.022
ion transmembrane transport GO:0034220 365 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
Human Rat
cation transport GO:0006812 382 0.022
regulation of cellular component organization GO:0051128 368 0.022
monovalent inorganic cation transport GO:0015672 172 0.021
neuron projection morphogenesis GO:0048812 122 0.021
positive regulation of cell death GO:0010942 184 0.021
Rat
regulation of cell differentiation GO:0045595 320 0.021
camera type eye development GO:0043010 48 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
heterocycle catabolic process GO:0046700 167 0.020
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
macromolecular complex assembly GO:0065003 273 0.020
regulation of multicellular organismal development GO:2000026 376 0.020
brain development GO:0007420 247 0.020
detection of visible light GO:0009584 3 0.020
carboxylic acid metabolic process GO:0019752 289 0.020
regulation of signal transduction GO:0009966 318 0.020
oxoacid metabolic process GO:0043436 290 0.020
positive regulation of cell proliferation GO:0008284 249 0.020
ribonucleotide metabolic process GO:0009259 231 0.019
Human Rat
divalent metal ion transport GO:0070838 132 0.019
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
Human Rat
response to inorganic substance GO:0010035 377 0.019
sex differentiation GO:0007548 113 0.019
ribose phosphate biosynthetic process GO:0046390 87 0.019
Rat
positive regulation of programmed cell death GO:0043068 157 0.019
Rat
regulation of molecular function GO:0065009 398 0.019
nucleoside phosphate biosynthetic process GO:1901293 102 0.019
Rat
purine ribonucleotide metabolic process GO:0009150 227 0.019
Human Rat
regulation of peptide hormone secretion GO:0090276 80 0.019
heart morphogenesis GO:0003007 3 0.018
cellular calcium ion homeostasis GO:0006874 160 0.018
Human
negative regulation of apoptotic process GO:0043066 181 0.018
cellular component assembly GO:0022607 360 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
Human
catabolic process GO:0009056 351 0.018
Rat
camera type eye morphogenesis GO:0048593 2 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
retina morphogenesis in camera type eye GO:0060042 1 0.017
positive regulation of protein modification process GO:0031401 142 0.017
eye development GO:0001654 50 0.017
adult locomotory behavior GO:0008344 4 0.017
divalent inorganic cation homeostasis GO:0072507 165 0.017
Human
cell projection morphogenesis GO:0048858 123 0.017
gland development GO:0048732 155 0.017
axis specification GO:0009798 4 0.017
neurological system process GO:0050877 219 0.017
Rat
macromolecular complex subunit organization GO:0043933 339 0.017
organic acid metabolic process GO:0006082 292 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
Rat
response to acid chemical GO:0001101 222 0.017
response to calcium ion GO:0051592 59 0.017
protein complex subunit organization GO:0071822 302 0.016
protein complex assembly GO:0006461 263 0.016
response to ethanol GO:0045471 162 0.016
regulation of cell proliferation GO:0042127 359 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
Rat
cell part morphogenesis GO:0032990 123 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
Human
purine ribonucleoside metabolic process GO:0046128 168 0.016
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.016
lung development GO:0030324 43 0.016
purine nucleotide biosynthetic process GO:0006164 83 0.016
Rat
positive regulation of molecular function GO:0044093 230 0.016
peptide secretion GO:0002790 86 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
regulation of smooth muscle cell proliferation GO:0048660 75 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.015
circadian rhythm GO:0007623 88 0.015
negative regulation of cell differentiation GO:0045596 99 0.015
negative regulation of macromolecule metabolic process GO:0010605 260 0.015
metal ion homeostasis GO:0055065 186 0.015
Human
female gonad development GO:0008585 53 0.015
response to peptide hormone GO:0043434 278 0.015
ras protein signal transduction GO:0007265 29 0.015
positive regulation of nucleotide metabolic process GO:0045981 91 0.015
epithelial cell differentiation GO:0030855 71 0.015
Rat
cellular component morphogenesis GO:0032989 155 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
growth GO:0040007 165 0.015
response to ionizing radiation GO:0010212 59 0.015
cell cell signaling GO:0007267 335 0.015
glycosyl compound metabolic process GO:1901657 182 0.014
Human
negative regulation of programmed cell death GO:0043069 183 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
negative regulation of cell communication GO:0010648 158 0.014
gamete generation GO:0007276 124 0.014
development of primary sexual characteristics GO:0045137 107 0.014
organelle organization GO:0006996 266 0.014
Rat
single organism organelle organization GO:1902589 180 0.014
bmp signaling pathway GO:0030509 4 0.014
regulation of neuron death GO:1901214 115 0.014
negative regulation of cellular metabolic process GO:0031324 281 0.014
Rat
epithelium development GO:0060429 96 0.014
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
forebrain development GO:0030900 98 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
cytoskeleton organization GO:0007010 111 0.013
cellular protein localization GO:0034613 122 0.013
Rat
heart process GO:0003015 57 0.013
Rat
response to light stimulus GO:0009416 52 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
Rat
retina development in camera type eye GO:0060041 27 0.013
calcium ion homeostasis GO:0055074 162 0.013
Human
neuron development GO:0048666 286 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
response to growth factor GO:0070848 189 0.013
negative regulation of gene expression GO:0010629 199 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
negative regulation of transport GO:0051051 136 0.013
purine containing compound biosynthetic process GO:0072522 85 0.013
Rat
positive regulation of cell development GO:0010720 176 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
Rat
response to cytokine GO:0034097 215 0.013
regulation of neuron differentiation GO:0045664 208 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
regulation of notch signaling pathway GO:0008593 3 0.013
cell projection organization GO:0030030 302 0.013
negative regulation of molecular function GO:0044092 133 0.013
protein complex biogenesis GO:0070271 263 0.013
positive regulation of signaling GO:0023056 270 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.012
Rat
cardiovascular system development GO:0072358 134 0.012
meiotic cell cycle process GO:1903046 3 0.012
cell type specific apoptotic process GO:0097285 134 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
Rat
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
Rat
cation homeostasis GO:0055080 195 0.012
Human
response to temperature stimulus GO:0009266 94 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
cyclic nucleotide metabolic process GO:0009187 80 0.012
Rat
nucleoside metabolic process GO:0009116 179 0.012
Human
regulation of neurogenesis GO:0050767 247 0.012
vasculature development GO:0001944 70 0.012
negative regulation of signaling GO:0023057 157 0.012
detection of stimulus GO:0051606 24 0.012
muscle structure development GO:0061061 87 0.012
multi organism reproductive process GO:0044703 262 0.012
regulation of growth GO:0040008 105 0.012
striated muscle tissue development GO:0014706 58 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
purine ribonucleotide biosynthetic process GO:0009152 81 0.012
Rat
nucleotide catabolic process GO:0009166 139 0.012
Rat
divalent inorganic cation transport GO:0072511 134 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
Rat
regulation of intracellular signal transduction GO:1902531 218 0.011
chemical homeostasis GO:0048878 292 0.011
Human
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.011
regulation of protein modification process GO:0031399 194 0.011
visual perception GO:0007601 3 0.011
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.011
regulation of cellular localization GO:0060341 263 0.011
amide transport GO:0042886 105 0.011
peptidyl amino acid modification GO:0018193 126 0.011
respiratory system development GO:0060541 45 0.011
sensory perception of light stimulus GO:0050953 3 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
peptide transport GO:0015833 97 0.011
gonad development GO:0008406 104 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.010
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
negative regulation of secretion by cell GO:1903531 72 0.010
multicellular organism growth GO:0035264 1 0.010
regulation of nervous system development GO:0051960 264 0.010
urinary bladder smooth muscle contraction GO:0014832 4 0.010
sensory perception GO:0007600 101 0.010
macromolecule localization GO:0033036 252 0.010
Rat
response to estrogen GO:0043627 232 0.010
regulation of neuron projection development GO:0010975 161 0.010
response to decreased oxygen levels GO:0036293 237 0.010
Rat
response to zinc ion GO:0010043 39 0.010
regulation of protein kinase activity GO:0045859 105 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
Rat
purine nucleotide catabolic process GO:0006195 136 0.010
Rat
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
Rat
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
hematopoietic progenitor cell differentiation GO:0002244 2 0.010
organic substance catabolic process GO:1901575 316 0.010
Rat
ovulation cycle GO:0042698 67 0.010

Pde6b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.400
Human
disease of anatomical entity DOID:7 0 0.400
Human
eye and adnexa disease DOID:1492 0 0.400
Human
nervous system disease DOID:863 0 0.400
Human
eye disease DOID:5614 0 0.400
Human
retinal disease DOID:5679 0 0.208
Human
retinal degeneration DOID:8466 0 0.208
Human
retinitis pigmentosa DOID:10584 0 0.208
Human
night blindness DOID:8499 0 0.045
Human
musculoskeletal system disease DOID:17 0 0.011