Rattus norvegicus

0 known processes

Thoc2

THO complex 2

(Aliases: RGD1561623)

Thoc2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of rna biosynthetic process GO:2001141 381 0.205
reproduction GO:0000003 245 0.184
transcription dna templated GO:0006351 377 0.179
protein complex subunit organization GO:0071822 302 0.135
regulation of transcription dna templated GO:0006355 374 0.130
nucleic acid templated transcription GO:0097659 379 0.129
rna metabolic process GO:0016070 406 0.123
regulation of rna metabolic process GO:0051252 391 0.108
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.107
apoptotic process GO:0006915 381 0.103
multicellular organism reproduction GO:0032504 233 0.099
response to monosaccharide GO:0034284 159 0.098
positive regulation of transcription dna templated GO:0045893 197 0.097
cellular component biogenesis GO:0044085 368 0.095
multi organism reproductive process GO:0044703 262 0.094
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.094
rhythmic process GO:0048511 156 0.090
reproductive process GO:0022414 372 0.087
negative regulation of metabolic process GO:0009892 331 0.073
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.073
single organism reproductive process GO:0044702 297 0.072
regulation of nucleic acid templated transcription GO:1903506 380 0.071
response to hexose GO:0009746 144 0.070
protein oligomerization GO:0051259 191 0.070
protein complex assembly GO:0006461 263 0.067
cellular component assembly GO:0022607 360 0.065
positive regulation of response to stimulus GO:0048584 285 0.064
positive regulation of multicellular organismal process GO:0051240 387 0.064
gland development GO:0048732 155 0.062
intracellular signal transduction GO:0035556 314 0.060
rna biosynthetic process GO:0032774 380 0.060
response to oxygen levels GO:0070482 265 0.060
carbohydrate derivative metabolic process GO:1901135 346 0.059
positive regulation of rna metabolic process GO:0051254 203 0.059
cation transport GO:0006812 382 0.057
cellular response to endogenous stimulus GO:0071495 377 0.057
regulation of cellular protein metabolic process GO:0032268 267 0.057
regulation of molecular function GO:0065009 398 0.057
regulation of cellular component organization GO:0051128 368 0.056
protein complex biogenesis GO:0070271 263 0.056
tissue development GO:0009888 252 0.054
response to peptide hormone GO:0043434 278 0.054
positive regulation of biosynthetic process GO:0009891 319 0.053
multicellular organismal reproductive process GO:0048609 233 0.050
organophosphate metabolic process GO:0019637 370 0.050
organic substance catabolic process GO:1901575 316 0.049
cellular response to hormone stimulus GO:0032870 247 0.049
macromolecule localization GO:0033036 252 0.049
epithelium development GO:0060429 96 0.049
purine nucleoside triphosphate metabolic process GO:0009144 141 0.048
transforming growth factor beta receptor complex assembly GO:0007181 2 0.047
positive regulation of gene expression GO:0010628 244 0.047
regulation of phosphate metabolic process GO:0019220 349 0.047
positive regulation of cellular biosynthetic process GO:0031328 295 0.047
nucleoside phosphate metabolic process GO:0006753 283 0.047
anatomical structure morphogenesis GO:0009653 298 0.047
programmed cell death GO:0012501 392 0.047
response to toxic substance GO:0009636 133 0.046
protein phosphorylation GO:0006468 345 0.046
macromolecular complex subunit organization GO:0043933 339 0.045
negative regulation of macromolecule metabolic process GO:0010605 260 0.045
nucleobase containing small molecule metabolic process GO:0055086 316 0.045
response to decreased oxygen levels GO:0036293 237 0.044
response to carbohydrate GO:0009743 183 0.043
secretion GO:0046903 307 0.043
organelle organization GO:0006996 266 0.043
regulation of growth GO:0040008 105 0.043
macromolecular complex assembly GO:0065003 273 0.042
growth GO:0040007 165 0.042
secretion by cell GO:0032940 248 0.041
regulation of programmed cell death GO:0043067 341 0.041
positive regulation of signaling GO:0023056 270 0.041
regulation of catalytic activity GO:0050790 304 0.040
positive regulation of transport GO:0051050 245 0.040
cellular catabolic process GO:0044248 295 0.039
positive regulation of phosphate metabolic process GO:0045937 262 0.039
male mating behavior GO:0060179 3 0.038
response to glucose GO:0009749 136 0.038
regulation of apoptotic process GO:0042981 335 0.038
response to peptide GO:1901652 292 0.037
positive regulation of developmental process GO:0051094 283 0.037
regulation of multicellular organismal development GO:2000026 376 0.037
organic acid metabolic process GO:0006082 292 0.037
response to metal ion GO:0010038 253 0.036
brain development GO:0007420 247 0.036
response to corticosteroid GO:0031960 235 0.036
central nervous system development GO:0007417 311 0.036
cell adhesion GO:0007155 110 0.036
response to acid chemical GO:0001101 222 0.036
cell projection organization GO:0030030 302 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.035
regulation of signal transduction GO:0009966 318 0.035
response to temperature stimulus GO:0009266 94 0.035
catabolic process GO:0009056 351 0.035
response to hypoxia GO:0001666 231 0.035
cellular response to peptide GO:1901653 133 0.034
regulation of cellular localization GO:0060341 263 0.034
development of primary sexual characteristics GO:0045137 107 0.033
neuron projection morphogenesis GO:0048812 122 0.033
signal release GO:0023061 145 0.033
transcription from rna polymerase ii promoter GO:0006366 252 0.032
aging GO:0007568 241 0.032
response to estrogen GO:0043627 232 0.032
cellular response to stress GO:0033554 269 0.032
regulation of anatomical structure morphogenesis GO:0022603 141 0.032
regulation of neuron apoptotic process GO:0043523 83 0.031
positive regulation of cell communication GO:0010647 271 0.031
cell morphogenesis GO:0000902 142 0.031
oxoacid metabolic process GO:0043436 290 0.031
regulation of phosphorus metabolic process GO:0051174 349 0.031
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.031
cellular component morphogenesis GO:0032989 155 0.030
negative regulation of cellular metabolic process GO:0031324 281 0.030
positive regulation of cellular component organization GO:0051130 200 0.030
positive regulation of rna biosynthetic process GO:1902680 197 0.030
single organism catabolic process GO:0044712 283 0.030
microtubule organizing center organization GO:0031023 1 0.030
ribonucleotide metabolic process GO:0009259 231 0.029
protein localization GO:0008104 191 0.029
cell cell signaling GO:0007267 335 0.029
regulation of secretion GO:0051046 224 0.028
regulation of cell proliferation GO:0042127 359 0.028
regulation of cellular component biogenesis GO:0044087 86 0.028
neuron differentiation GO:0030182 368 0.028
regulation of protein metabolic process GO:0051246 289 0.028
regulation of neuron death GO:1901214 115 0.028
response to ketone GO:1901654 182 0.028
response to extracellular stimulus GO:0009991 380 0.028
negative regulation of cell death GO:0060548 229 0.028
response to cytokine GO:0034097 215 0.028
cell migration GO:0016477 197 0.028
hepaticobiliary system development GO:0061008 90 0.028
regulation of cell adhesion GO:0030155 52 0.027
purine ribonucleotide metabolic process GO:0009150 227 0.027
multicellular organism growth GO:0035264 1 0.027
ion transmembrane transport GO:0034220 365 0.027
positive regulation of nucleic acid templated transcription GO:1903508 197 0.027
protein heterooligomerization GO:0051291 89 0.026
neuron death GO:0070997 127 0.026
response to ethanol GO:0045471 162 0.026
regulation of transmembrane transport GO:0034762 122 0.026
head development GO:0060322 247 0.026
response to inorganic substance GO:0010035 377 0.025
ossification GO:0001503 70 0.025
lipid metabolic process GO:0006629 283 0.025
negative regulation of gene expression GO:0010629 199 0.025
regulation of secretion by cell GO:1903530 208 0.025
carboxylic acid metabolic process GO:0019752 289 0.025
neuron development GO:0048666 286 0.025
cellular chemical homeostasis GO:0055082 247 0.025
cell motility GO:0048870 202 0.025
regulation of system process GO:0044057 208 0.025
response to glucocorticoid GO:0051384 223 0.025
positive regulation of skeletal muscle tissue regeneration GO:0043415 1 0.024
cellular component movement GO:0006928 248 0.024
nucleotide metabolic process GO:0009117 279 0.024
organophosphate biosynthetic process GO:0090407 143 0.024
positive regulation of secretion GO:0051047 140 0.024
cell cycle process GO:0022402 57 0.024
cellular amino acid metabolic process GO:0006520 107 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.023
purine nucleotide metabolic process GO:0006163 229 0.023
negative regulation of apoptotic process GO:0043066 181 0.023
hormone secretion GO:0046879 115 0.023
transmembrane transport GO:0055085 412 0.023
cellular response to oxygen containing compound GO:1901701 386 0.023
response to nutrient levels GO:0031667 370 0.023
nitrogen compound transport GO:0071705 229 0.023
negative regulation of cell communication GO:0010648 158 0.023
cellular homeostasis GO:0019725 252 0.023
reproductive structure development GO:0048608 128 0.023
multi multicellular organism process GO:0044706 138 0.022
single organism biosynthetic process GO:0044711 342 0.022
purine containing compound metabolic process GO:0072521 253 0.022
positive regulation of cell proliferation GO:0008284 249 0.022
localization of cell GO:0051674 202 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.022
negative regulation of molecular function GO:0044092 133 0.022
circulatory system development GO:0072359 134 0.022
cellular response to growth factor stimulus GO:0071363 162 0.022
cellular macromolecule localization GO:0070727 122 0.021
neuron apoptotic process GO:0051402 88 0.021
regulation of protein phosphorylation GO:0001932 183 0.021
regulation of hormone secretion GO:0046883 106 0.021
organ regeneration GO:0031100 101 0.021
cell morphogenesis involved in differentiation GO:0000904 119 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
cellular response to organonitrogen compound GO:0071417 197 0.021
negative regulation of programmed cell death GO:0043069 183 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
cell cycle GO:0007049 101 0.020
circadian rhythm GO:0007623 88 0.020
metal ion transport GO:0030001 289 0.020
regulation of body fluid levels GO:0050878 90 0.020
aromatic compound catabolic process GO:0019439 168 0.019
negative regulation of catalytic activity GO:0043086 103 0.019
locomotion GO:0040011 237 0.019
heterocycle catabolic process GO:0046700 167 0.019
negative regulation of neuron apoptotic process GO:0043524 45 0.019
synaptic growth at neuromuscular junction GO:0051124 1 0.019
vasculogenesis GO:0001570 3 0.019
action potential GO:0001508 54 0.019
cell projection morphogenesis GO:0048858 123 0.019
developmental process involved in reproduction GO:0003006 159 0.019
positive regulation of molecular function GO:0044093 230 0.019
chemical homeostasis GO:0048878 292 0.019
negative regulation of transcription dna templated GO:0045892 116 0.018
negative regulation of cardiac muscle tissue development GO:0055026 3 0.018
negative regulation of organ growth GO:0046621 3 0.018
purine nucleoside metabolic process GO:0042278 169 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.018
regulation of cellular component movement GO:0051270 150 0.018
cation transmembrane transport GO:0098655 263 0.018
glycosyl compound metabolic process GO:1901657 182 0.018
cellular response to steroid hormone stimulus GO:0071383 93 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
sexual reproduction GO:0019953 148 0.018
response to insulin GO:0032868 133 0.018
homeostatic process GO:0042592 331 0.018
actin cytoskeleton organization GO:0030036 73 0.018
muscle structure development GO:0061061 87 0.017
response to estradiol GO:0032355 164 0.017
gonad development GO:0008406 104 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
positive regulation of signal transduction GO:0009967 175 0.017
carbohydrate derivative biosynthetic process GO:1901137 124 0.017
gamete generation GO:0007276 124 0.017
single organism organelle organization GO:1902589 180 0.017
axis specification GO:0009798 4 0.017
hormone transport GO:0009914 121 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
negative regulation of transport GO:0051051 136 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
cell part morphogenesis GO:0032990 123 0.017
axonogenesis GO:0007409 71 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
response to growth factor GO:0070848 189 0.016
development of primary female sexual characteristics GO:0046545 56 0.016
response to transition metal nanoparticle GO:1990267 122 0.016
positive regulation of secretion by cell GO:1903532 128 0.016
anterior posterior pattern specification GO:0009952 1 0.016
regulation of muscle contraction GO:0006937 53 0.016
sex differentiation GO:0007548 113 0.016
response to transforming growth factor beta GO:0071559 46 0.016
cellular amine metabolic process GO:0044106 38 0.016
maintenance of location GO:0051235 17 0.016
camp biosynthetic process GO:0006171 47 0.016
response to radiation GO:0009314 137 0.016
muscle system process GO:0003012 115 0.016
regulation of cell development GO:0060284 263 0.016
lipid biosynthetic process GO:0008610 128 0.016
organic cyclic compound catabolic process GO:1901361 175 0.015
cytoplasmic transport GO:0016482 115 0.015
positive regulation of protein modification process GO:0031401 142 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
regulation of protein modification process GO:0031399 194 0.015
regulation of developmental growth GO:0048638 45 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
nucleoside metabolic process GO:0009116 179 0.015
formation of primary germ layer GO:0001704 1 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
cellular ketone metabolic process GO:0042180 51 0.015
inorganic cation transmembrane transport GO:0098662 202 0.015
purine containing compound catabolic process GO:0072523 138 0.015
regulation of membrane potential GO:0042391 110 0.015
metal ion homeostasis GO:0055065 186 0.015
establishment of protein localization GO:0045184 141 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
cell cycle checkpoint GO:0000075 2 0.015
hexose metabolic process GO:0019318 58 0.015
axon development GO:0061564 96 0.015
single organism behavior GO:0044708 130 0.015
response to heat GO:0009408 60 0.015
morphogenesis of an epithelium GO:0002009 20 0.015
regulation of establishment of protein localization GO:0070201 69 0.015
regulation of hormone levels GO:0010817 187 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
protein transport GO:0015031 132 0.014
cellular response to peptide hormone stimulus GO:0071375 120 0.014
negative regulation of neuron death GO:1901215 69 0.014
regulation of cell projection organization GO:0031344 175 0.014
liver development GO:0001889 90 0.014
carbohydrate metabolic process GO:0005975 130 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
regulation of homeostatic process GO:0032844 101 0.014
nucleotide catabolic process GO:0009166 139 0.014
response to electrical stimulus GO:0051602 56 0.014
regulation of phosphorylation GO:0042325 248 0.014
protein autophosphorylation GO:0046777 66 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
developmental growth GO:0048589 100 0.014
intracellular transport GO:0046907 185 0.014
vesicle mediated transport GO:0016192 181 0.014
nucleoside triphosphate metabolic process GO:0009141 144 0.014
positive regulation of cell death GO:0010942 184 0.013
reproductive system development GO:0061458 128 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
tube development GO:0035295 89 0.013
regeneration GO:0031099 163 0.013
glucose metabolic process GO:0006006 52 0.013
appendage morphogenesis GO:0035107 4 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
neuron projection development GO:0031175 273 0.013
cell type specific apoptotic process GO:0097285 134 0.013
mesoderm development GO:0007498 2 0.013
response to lipopolysaccharide GO:0032496 191 0.013
peptide secretion GO:0002790 86 0.013
regulation of protein localization GO:0032880 81 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
insulin secretion GO:0030073 69 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.012
protein maturation GO:0051604 68 0.012
regulation of cell migration GO:0030334 128 0.012
response to mechanical stimulus GO:0009612 134 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
regulation of ion transport GO:0043269 245 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
lipid storage GO:0019915 1 0.012
response to fatty acid GO:0070542 65 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
proteolysis GO:0006508 175 0.012
muscle contraction GO:0006936 88 0.012
behavior GO:0007610 205 0.012
divalent metal ion transport GO:0070838 132 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
regulation of peptide secretion GO:0002791 82 0.012
centrosome organization GO:0051297 1 0.012
chromosome segregation GO:0007059 2 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
response to calcium ion GO:0051592 59 0.012
positive regulation of cellular component biogenesis GO:0044089 55 0.012
positive regulation of growth GO:0045927 55 0.012
response to wounding GO:0009611 254 0.012
response to nutrient GO:0007584 248 0.011
cellular protein complex assembly GO:0043623 44 0.011
cell activation GO:0001775 97 0.011
defecation GO:0030421 1 0.011
regulation of peptidase activity GO:0052547 55 0.011
muscle organ development GO:0007517 50 0.011
response to vitamin GO:0033273 131 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
calcium ion homeostasis GO:0055074 162 0.011
regulation of blood circulation GO:1903522 110 0.011
protein homooligomerization GO:0051260 91 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
epithelial cell differentiation GO:0030855 71 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
transmission of nerve impulse GO:0019226 42 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
embryonic appendage morphogenesis GO:0035113 4 0.011
regulation of anatomical structure size GO:0090066 135 0.011
regulation of lipid metabolic process GO:0019216 68 0.011
male gamete generation GO:0048232 99 0.011
regulation of mrna splicing via spliceosome GO:0048024 3 0.011
regulation of skeletal muscle tissue regeneration GO:0043416 2 0.011
negative regulation of cardiac muscle cell proliferation GO:0060044 2 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
spermatogenesis GO:0007283 99 0.011
cellular response to glucocorticoid stimulus GO:0071385 68 0.011
muscle tissue development GO:0060537 58 0.011
single organism cellular localization GO:1902580 102 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
monosaccharide metabolic process GO:0005996 61 0.011
regulation of gluconeogenesis GO:0006111 4 0.011
protein processing GO:0016485 68 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
regulation of nervous system development GO:0051960 264 0.011
response to amino acid GO:0043200 75 0.011
biological adhesion GO:0022610 110 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010
regulation of calcium ion transport GO:0051924 77 0.010
positive regulation of homeostatic process GO:0032846 49 0.010
positive regulation of hormone secretion GO:0046887 65 0.010
regulation of hydrolase activity GO:0051336 143 0.010
locomotor rhythm GO:0045475 1 0.010
multicellular organismal signaling GO:0035637 44 0.010
respiratory system development GO:0060541 45 0.010
positive regulation of nervous system development GO:0051962 178 0.010
peptide transport GO:0015833 97 0.010
rna localization GO:0006403 4 0.010
regulation of cellular catabolic process GO:0031329 101 0.010
neuromuscular synaptic transmission GO:0007274 2 0.010
response to external biotic stimulus GO:0043207 221 0.010
regulation of cell motility GO:2000145 131 0.010
divalent inorganic cation transport GO:0072511 134 0.010
anion transport GO:0006820 178 0.010
response to camp GO:0051591 91 0.010

Thoc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015