Rattus norvegicus

0 known processes

Wwc2

WW and C2 domain containing 2

(Aliases: RGD1559427)

Wwc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of phosphate metabolic process GO:0019220 349 0.116
intracellular signal transduction GO:0035556 314 0.097
Human
regulation of phosphorylation GO:0042325 248 0.093
negative regulation of multicellular organismal process GO:0051241 203 0.080
Human
protein phosphorylation GO:0006468 345 0.074
regulation of phosphorus metabolic process GO:0051174 349 0.074
positive regulation of phosphorus metabolic process GO:0010562 262 0.068
positive regulation of phosphate metabolic process GO:0045937 262 0.067
regulation of intracellular signal transduction GO:1902531 218 0.064
Human
metal ion transport GO:0030001 289 0.062
ion transmembrane transport GO:0034220 365 0.059
cell projection organization GO:0030030 302 0.057
regulation of molecular function GO:0065009 398 0.053
carboxylic acid metabolic process GO:0019752 289 0.052
neuron projection development GO:0031175 273 0.051
regulation of signal transduction GO:0009966 318 0.050
Human
positive regulation of intracellular signal transduction GO:1902533 138 0.049
positive regulation of cell communication GO:0010647 271 0.049
regulation of multicellular organismal development GO:2000026 376 0.048
organic acid metabolic process GO:0006082 292 0.047
transmembrane transport GO:0055085 412 0.046
rna metabolic process GO:0016070 406 0.046
Human
signal transduction by phosphorylation GO:0023014 144 0.046
neuron development GO:0048666 286 0.045
aging GO:0007568 241 0.045
positive regulation of cellular component organization GO:0051130 200 0.045
response to nutrient levels GO:0031667 370 0.045
cation transport GO:0006812 382 0.044
negative regulation of developmental process GO:0051093 125 0.044
Human
amine metabolic process GO:0009308 38 0.044
single organism reproductive process GO:0044702 297 0.043
cellular response to growth factor stimulus GO:0071363 162 0.043
g protein coupled receptor signaling pathway GO:0007186 242 0.042
positive regulation of phosphorylation GO:0042327 177 0.042
inorganic cation transmembrane transport GO:0098662 202 0.041
negative regulation of cell proliferation GO:0008285 119 0.041
cellular amine metabolic process GO:0044106 38 0.041
regulation of cellular component organization GO:0051128 368 0.041
negative regulation of signaling GO:0023057 157 0.040
Human
regulation of protein modification process GO:0031399 194 0.040
neuron differentiation GO:0030182 368 0.039
regulation of cell development GO:0060284 263 0.039
cellular response to oxygen containing compound GO:1901701 386 0.038
rhythmic process GO:0048511 156 0.038
programmed cell death GO:0012501 392 0.038
transcription dna templated GO:0006351 377 0.038
Human
positive regulation of signal transduction GO:0009967 175 0.038
oxoacid metabolic process GO:0043436 290 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.037
macromolecular complex subunit organization GO:0043933 339 0.036
regulation of cell differentiation GO:0045595 320 0.036
cation transmembrane transport GO:0098655 263 0.036
regulation of protein metabolic process GO:0051246 289 0.036
regulation of cellular amine metabolic process GO:0033238 8 0.035
macromolecule localization GO:0033036 252 0.035
cation homeostasis GO:0055080 195 0.035
regulation of neuron differentiation GO:0045664 208 0.035
regulation of neurogenesis GO:0050767 247 0.034
regulation of nervous system development GO:0051960 264 0.034
reproduction GO:0000003 245 0.034
regulation of nucleic acid templated transcription GO:1903506 380 0.034
Human
regulation of catalytic activity GO:0050790 304 0.034
regulation of cellular amino acid metabolic process GO:0006521 2 0.034
cellular amino acid metabolic process GO:0006520 107 0.034
central nervous system development GO:0007417 311 0.033
organelle organization GO:0006996 266 0.033
reproductive process GO:0022414 372 0.033
cellular component movement GO:0006928 248 0.033
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.033
Human
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
synaptic growth at neuromuscular junction GO:0051124 1 0.032
regulation of protein phosphorylation GO:0001932 183 0.032
response to decreased oxygen levels GO:0036293 237 0.032
cellular component biogenesis GO:0044085 368 0.032
multi organism reproductive process GO:0044703 262 0.032
negative regulation of nervous system development GO:0051961 79 0.032
regulation of rna biosynthetic process GO:2001141 381 0.032
Human
negative regulation of metabolic process GO:0009892 331 0.031
Human
response to nutrient GO:0007584 248 0.031
positive regulation of signaling GO:0023056 270 0.031
locomotion GO:0040011 237 0.031
Rat
cellular response to endogenous stimulus GO:0071495 377 0.031
cellular response to stress GO:0033554 269 0.030
response to corticosteroid GO:0031960 235 0.030
positive regulation of response to stimulus GO:0048584 285 0.030
brain development GO:0007420 247 0.030
regulation of cell proliferation GO:0042127 359 0.029
head development GO:0060322 247 0.029
negative regulation of cell communication GO:0010648 158 0.029
Human
organonitrogen compound biosynthetic process GO:1901566 167 0.029
response to growth factor GO:0070848 189 0.028
mapk cascade GO:0000165 140 0.028
regulation of ion transport GO:0043269 245 0.028
heart morphogenesis GO:0003007 3 0.028
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.028
response to extracellular stimulus GO:0009991 380 0.028
regulation of membrane potential GO:0042391 110 0.028
inorganic ion transmembrane transport GO:0098660 229 0.028
vesicle mediated transport GO:0016192 181 0.028
single organism organelle organization GO:1902589 180 0.028
positive regulation of protein metabolic process GO:0051247 178 0.027
positive regulation of molecular function GO:0044093 230 0.027
positive regulation of cell proliferation GO:0008284 249 0.027
cellular chemical homeostasis GO:0055082 247 0.027
response to estradiol GO:0032355 164 0.027
cellular response to organic cyclic compound GO:0071407 202 0.027
glycosyl compound metabolic process GO:1901657 182 0.027
anterior posterior pattern specification GO:0009952 1 0.027
regulation of ion transmembrane transport GO:0034765 121 0.027
cellular component assembly GO:0022607 360 0.026
cell morphogenesis GO:0000902 142 0.026
response to wounding GO:0009611 254 0.026
multicellular organism reproduction GO:0032504 233 0.026
monovalent inorganic cation transport GO:0015672 172 0.026
ion homeostasis GO:0050801 212 0.026
cellular response to hormone stimulus GO:0032870 247 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.025
apoptotic process GO:0006915 381 0.025
neurological system process GO:0050877 219 0.025
positive regulation of protein modification process GO:0031401 142 0.025
negative regulation of cell differentiation GO:0045596 99 0.025
anatomical structure morphogenesis GO:0009653 298 0.025
bmp signaling pathway GO:0030509 4 0.025
cellular ketone metabolic process GO:0042180 51 0.025
regulation of neuron projection development GO:0010975 161 0.025
organophosphate metabolic process GO:0019637 370 0.025
negative regulation of response to stimulus GO:0048585 155 0.025
Human
multicellular organismal reproductive process GO:0048609 233 0.025
localization of cell GO:0051674 202 0.025
Rat
response to oxygen levels GO:0070482 265 0.025
positive regulation of catalytic activity GO:0043085 184 0.024
circulatory system development GO:0072359 134 0.024
cell cycle GO:0007049 101 0.024
cell type specific apoptotic process GO:0097285 134 0.024
cellular homeostasis GO:0019725 252 0.024
regulation of apoptotic process GO:0042981 335 0.024
endocytosis GO:0006897 84 0.024
positive regulation of multicellular organismal process GO:0051240 387 0.024
cell morphogenesis involved in differentiation GO:0000904 119 0.024
regulation of metal ion transport GO:0010959 118 0.023
positive regulation of cell death GO:0010942 184 0.023
positive regulation of cellular protein metabolic process GO:0032270 167 0.023
regulation of mapk cascade GO:0043408 116 0.023
positive regulation of neurogenesis GO:0050769 165 0.023
positive regulation of protein phosphorylation GO:0001934 135 0.023
cardiovascular system development GO:0072358 134 0.023
regulation of system process GO:0044057 208 0.023
protein complex subunit organization GO:0071822 302 0.023
protein complex biogenesis GO:0070271 263 0.023
nucleic acid templated transcription GO:0097659 379 0.023
Human
chemical homeostasis GO:0048878 292 0.023
positive regulation of biosynthetic process GO:0009891 319 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
cell motility GO:0048870 202 0.022
Rat
intracellular transport GO:0046907 185 0.022
action potential GO:0001508 54 0.022
regulation of transcription dna templated GO:0006355 374 0.022
Human
regulation of protein kinase activity GO:0045859 105 0.021
ribonucleotide metabolic process GO:0009259 231 0.021
protein complex assembly GO:0006461 263 0.021
growth GO:0040007 165 0.021
Human
cellular metal ion homeostasis GO:0006875 172 0.021
response to radiation GO:0009314 137 0.021
regulation of transferase activity GO:0051338 123 0.021
axonogenesis GO:0007409 71 0.021
response to biotic stimulus GO:0009607 226 0.021
positive regulation of cell development GO:0010720 176 0.021
salivary gland development GO:0007431 3 0.021
negative regulation of molecular function GO:0044092 133 0.021
immune system process GO:0002376 204 0.020
regulation of cell cycle GO:0051726 73 0.020
cellular response to nitrogen compound GO:1901699 210 0.020
purine nucleoside metabolic process GO:0042278 169 0.020
cell cell signaling GO:0007267 335 0.020
response to hypoxia GO:0001666 231 0.020
regulation of rna metabolic process GO:0051252 391 0.020
Human
regulation of kinase activity GO:0043549 117 0.020
potassium ion transport GO:0006813 97 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
muscle system process GO:0003012 115 0.020
regulation of cellular localization GO:0060341 263 0.020
multicellular organismal signaling GO:0035637 44 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
protein localization GO:0008104 191 0.019
protein oligomerization GO:0051259 191 0.019
neuronal action potential GO:0019228 35 0.019
circulatory system process GO:0003013 183 0.019
cellular component morphogenesis GO:0032989 155 0.019
axis specification GO:0009798 4 0.019
transmission of nerve impulse GO:0019226 42 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
sexual reproduction GO:0019953 148 0.019
regulation of transmembrane transporter activity GO:0022898 49 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
Human
ras protein signal transduction GO:0007265 29 0.019
cellular cation homeostasis GO:0030003 180 0.019
synaptic transmission GO:0007268 235 0.018
regulation of cell projection organization GO:0031344 175 0.018
positive regulation of neuron differentiation GO:0045666 126 0.018
positive regulation of kinase activity GO:0033674 77 0.018
positive regulation of nervous system development GO:0051962 178 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
positive regulation of mapk cascade GO:0043410 92 0.018
homeostatic process GO:0042592 331 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
tissue development GO:0009888 252 0.018
vasculature development GO:0001944 70 0.018
transcription from rna polymerase ii promoter GO:0006366 252 0.018
Human
somatic stem cell division GO:0048103 2 0.018
regulation of programmed cell death GO:0043067 341 0.018
stress activated protein kinase signaling cascade GO:0031098 37 0.018
response to inorganic substance GO:0010035 377 0.017
positive regulation of developmental process GO:0051094 283 0.017
anion transport GO:0006820 178 0.017
response to metal ion GO:0010038 253 0.017
cell part morphogenesis GO:0032990 123 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
rna biosynthetic process GO:0032774 380 0.017
Human
response to estrogen GO:0043627 232 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
Human
positive regulation of neuron projection development GO:0010976 99 0.017
taxis GO:0042330 67 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
Human
positive regulation of transcription dna templated GO:0045893 197 0.017
cell projection morphogenesis GO:0048858 123 0.017
enzyme linked receptor protein signaling pathway GO:0007167 116 0.017
macromolecular complex assembly GO:0065003 273 0.017
blood circulation GO:0008015 183 0.017
developmental growth GO:0048589 100 0.017
Human
ribonucleoside metabolic process GO:0009119 174 0.017
wound healing GO:0042060 122 0.017
response to acid chemical GO:0001101 222 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
regulation of cellular component movement GO:0051270 150 0.017
developmental process involved in reproduction GO:0003006 159 0.017
regulation of hydrolase activity GO:0051336 143 0.017
regulation of transmembrane transport GO:0034762 122 0.017
positive regulation of rna biosynthetic process GO:1902680 197 0.017
actin filament based process GO:0030029 86 0.016
single organism biosynthetic process GO:0044711 342 0.016
positive regulation of gene expression GO:0010628 244 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
cytoskeleton organization GO:0007010 111 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
behavior GO:0007610 205 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
regulation of canonical wnt signaling pathway GO:0060828 4 0.016
chromosome segregation GO:0007059 2 0.016
negative regulation of cell development GO:0010721 82 0.016
development of primary sexual characteristics GO:0045137 107 0.016
neuromuscular process GO:0050905 2 0.016
response to cytokine GO:0034097 215 0.016
mesoderm development GO:0007498 2 0.016
negative regulation of phosphorus metabolic process GO:0010563 80 0.016
calcium ion homeostasis GO:0055074 162 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
cellular ion homeostasis GO:0006873 184 0.015
negative regulation of neurogenesis GO:0050768 78 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
axon development GO:0061564 96 0.015
maintenance of location GO:0051235 17 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
single organism cellular localization GO:1902580 102 0.015
inflammatory response GO:0006954 150 0.015
chemotaxis GO:0006935 66 0.015
response to lipopolysaccharide GO:0032496 191 0.015
cytoplasmic transport GO:0016482 115 0.015
positive regulation of transferase activity GO:0051347 81 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
Human
positive regulation of transport GO:0051050 245 0.015
catabolic process GO:0009056 351 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
dendrite development GO:0016358 72 0.015
nucleoside metabolic process GO:0009116 179 0.015
positive regulation of protein kinase activity GO:0045860 73 0.015
defense response GO:0006952 194 0.015
negative regulation of transport GO:0051051 136 0.015
nucleotide metabolic process GO:0009117 279 0.015
negative regulation of signal transduction GO:0009968 83 0.015
Human
nucleoside phosphate metabolic process GO:0006753 283 0.015
cell growth GO:0016049 104 0.015
regulation of stem cell differentiation GO:2000736 2 0.014
spindle organization GO:0007051 2 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
response to external biotic stimulus GO:0043207 221 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
ovulation cycle GO:0042698 67 0.014
immune response GO:0006955 104 0.014
response to tumor necrosis factor GO:0034612 56 0.014
regulation of vesicle mediated transport GO:0060627 81 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
response to peptide hormone GO:0043434 278 0.014
regulation of ion transmembrane transporter activity GO:0032412 48 0.014
cellular response to peptide GO:1901653 133 0.014
response to peptide GO:1901652 292 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
purine containing compound metabolic process GO:0072521 253 0.014
gtp metabolic process GO:0046039 72 0.014
sodium ion transport GO:0006814 82 0.014
regulation of developmental growth GO:0048638 45 0.014
Human
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
single organism intracellular transport GO:1902582 166 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
gtp catabolic process GO:0006184 71 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
cell migration GO:0016477 197 0.014
Rat
gland development GO:0048732 155 0.014
regulation of cell growth GO:0001558 85 0.014
receptor mediated endocytosis GO:0006898 42 0.014
epithelium development GO:0060429 96 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
regulation of anatomical structure size GO:0090066 135 0.014
cell fate determination GO:0001709 2 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
regulation of growth GO:0040008 105 0.013
Human
carboxylic acid transport GO:0046942 115 0.013
rho protein signal transduction GO:0007266 11 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
metal ion homeostasis GO:0055065 186 0.013
regeneration GO:0031099 163 0.013
negative regulation of cardiac muscle tissue development GO:0055026 3 0.013
aromatic compound catabolic process GO:0019439 168 0.013
cellular protein localization GO:0034613 122 0.013
response to vitamin GO:0033273 131 0.013
cardiac ventricle development GO:0003231 1 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.013
nucleoside catabolic process GO:0009164 126 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
lipid metabolic process GO:0006629 283 0.013
regulation of cell morphogenesis GO:0022604 77 0.013
hair cycle GO:0042633 3 0.013
muscle tissue development GO:0060537 58 0.013
blood vessel development GO:0001568 69 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
regulation of synaptic transmission GO:0050804 141 0.013
multicellular organism growth GO:0035264 1 0.013
female pregnancy GO:0007565 122 0.013
negative regulation of protein metabolic process GO:0051248 114 0.012
dephosphorylation GO:0016311 98 0.012
muscle structure development GO:0061061 87 0.012
biological adhesion GO:0022610 110 0.012
response to other organism GO:0051707 220 0.012
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 3 0.012
purine containing compound catabolic process GO:0072523 138 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
cellular macromolecule localization GO:0070727 122 0.012
cellular catabolic process GO:0044248 295 0.012
neuron fate commitment GO:0048663 4 0.012
single organism catabolic process GO:0044712 283 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
Human
regulation of organelle organization GO:0033043 80 0.012
regulation of dendrite development GO:0050773 59 0.012
cellular response to abiotic stimulus GO:0071214 85 0.012
negative regulation of gene expression GO:0010629 199 0.012
Human
striated muscle tissue development GO:0014706 58 0.012
regulation of small gtpase mediated signal transduction GO:0051056 48 0.012
blood vessel morphogenesis GO:0048514 58 0.012
response to ketone GO:1901654 182 0.012
response to oxidative stress GO:0006979 186 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
carbohydrate derivative metabolic process GO:1901135 346 0.012
response to reactive oxygen species GO:0000302 120 0.012
positive regulation of catabolic process GO:0009896 78 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
regulation of actin cytoskeleton organization GO:0032956 30 0.011
nucleotide catabolic process GO:0009166 139 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
regulation of bmp signaling pathway GO:0030510 2 0.011
regulation of endocytosis GO:0030100 42 0.011
regulation of transporter activity GO:0032409 50 0.011
negative regulation of neuron differentiation GO:0045665 62 0.011
regulation of cell migration GO:0030334 128 0.011
eye development GO:0001654 50 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
organic substance catabolic process GO:1901575 316 0.011
response to bacterium GO:0009617 200 0.011
actin cytoskeleton organization GO:0030036 73 0.011
epithelial cell differentiation GO:0030855 71 0.011
neuron apoptotic process GO:0051402 88 0.011
stem cell division GO:0017145 4 0.011
response to carbohydrate GO:0009743 183 0.011
cardiac chamber development GO:0003205 1 0.011
divalent inorganic cation transport GO:0072511 134 0.011
hair follicle development GO:0001942 2 0.011
synapse organization GO:0050808 46 0.011
response to hexose GO:0009746 144 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
regulation of response to external stimulus GO:0032101 106 0.011
response to alkaloid GO:0043279 132 0.011
salivary gland morphogenesis GO:0007435 1 0.011
response to toxic substance GO:0009636 133 0.011
regulation of response to stress GO:0080134 126 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
molting cycle GO:0042303 3 0.011
nitrogen compound transport GO:0071705 229 0.011
regulation of fat cell differentiation GO:0045598 3 0.011
cellular lipid metabolic process GO:0044255 208 0.011
positive regulation of ion transport GO:0043270 94 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
protein heterooligomerization GO:0051291 89 0.010
embryonic pattern specification GO:0009880 1 0.010
cellular response to external stimulus GO:0071496 118 0.010
response to glucocorticoid GO:0051384 223 0.010
regulation of muscle system process GO:0090257 79 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
small molecule biosynthetic process GO:0044283 124 0.010
cell adhesion GO:0007155 110 0.010
gamete generation GO:0007276 124 0.010
mitotic spindle organization GO:0007052 2 0.010
regulation of catabolic process GO:0009894 113 0.010
ribose phosphate metabolic process GO:0019693 235 0.010
glycosyl compound catabolic process GO:1901658 126 0.010
cellular macromolecular complex assembly GO:0034622 58 0.010
gonad development GO:0008406 104 0.010
potassium ion transmembrane transport GO:0071805 71 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010
sex differentiation GO:0007548 113 0.010
cell cycle process GO:0022402 57 0.010
sulfur compound metabolic process GO:0006790 70 0.010
embryonic skeletal system morphogenesis GO:0048704 3 0.010
regulation of immune system process GO:0002682 123 0.010
sensory organ development GO:0007423 74 0.010
organic hydroxy compound metabolic process GO:1901615 115 0.010
regulation of purine nucleotide catabolic process GO:0033121 65 0.010
mitotic cell cycle process GO:1903047 35 0.010

Wwc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.032
disease of metabolism DOID:0014667 0 0.018
musculoskeletal system disease DOID:17 0 0.016
sensory system disease DOID:0050155 0 0.013
central nervous system disease DOID:331 0 0.012