Rattus norvegicus

17 known processes

Lhx2

LIM homeobox 2

(Aliases: Lh-2,LH2A)

Lhx2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transmembrane transport GO:0098655 263 0.125
transmembrane transport GO:0055085 412 0.106
regulation of cell development GO:0060284 263 0.102
cation transport GO:0006812 382 0.091
cell cell signaling GO:0007267 335 0.084
Rat
carboxylic acid metabolic process GO:0019752 289 0.081
anion transport GO:0006820 178 0.081
anatomical structure morphogenesis GO:0009653 298 0.072
Zebrafish Mouse Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.071
Mouse Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.065
Mouse Rat
regulation of system process GO:0044057 208 0.065
multi organism reproductive process GO:0044703 262 0.063
inorganic ion transmembrane transport GO:0098660 229 0.062
organic acid metabolic process GO:0006082 292 0.061
positive regulation of transcription dna templated GO:0045893 197 0.060
Mouse Rat
positive regulation of cell differentiation GO:0045597 217 0.060
regulation of ion transport GO:0043269 245 0.057
regulation of cell differentiation GO:0045595 320 0.052
regulation of neurogenesis GO:0050767 247 0.052
positive regulation of secretion GO:0051047 140 0.052
Rat
regulation of secretion GO:0051046 224 0.052
Rat
regulation of cellular localization GO:0060341 263 0.051
Rat
single organism reproductive process GO:0044702 297 0.050
regulation of nervous system development GO:0051960 264 0.048
single organism biosynthetic process GO:0044711 342 0.048
multicellular organismal reproductive process GO:0048609 233 0.047
synaptic transmission GO:0007268 235 0.047
regulation of cellular component organization GO:0051128 368 0.046
regulation of neuron differentiation GO:0045664 208 0.045
secretion GO:0046903 307 0.045
Rat
organic acid transport GO:0015849 116 0.045
regulation of molecular function GO:0065009 398 0.044
Mouse Rat
cell projection organization GO:0030030 302 0.044
Zebrafish Mouse Rat
secretion by cell GO:0032940 248 0.044
Rat
behavior GO:0007610 205 0.044
Zebrafish
cellular component assembly GO:0022607 360 0.042
neuron development GO:0048666 286 0.041
Zebrafish Mouse Rat
regulation of multicellular organismal development GO:2000026 376 0.041
nitrogen compound transport GO:0071705 229 0.039
Rat
cellular component biogenesis GO:0044085 368 0.039
programmed cell death GO:0012501 392 0.039
nucleic acid templated transcription GO:0097659 379 0.039
Mouse Rat
neuron differentiation GO:0030182 368 0.039
homeostatic process GO:0042592 331 0.038
reproductive process GO:0022414 372 0.037
regulation of intracellular signal transduction GO:1902531 218 0.037
vesicle mediated transport GO:0016192 181 0.037
regulation of neuron projection development GO:0010975 161 0.037
metal ion transport GO:0030001 289 0.037
oxoacid metabolic process GO:0043436 290 0.037
negative regulation of signaling GO:0023057 157 0.036
Rat
ion transmembrane transport GO:0034220 365 0.036
cellular amino acid metabolic process GO:0006520 107 0.036
neuron projection development GO:0031175 273 0.035
Zebrafish Mouse Rat
organophosphate metabolic process GO:0019637 370 0.035
cellular cation homeostasis GO:0030003 180 0.035
positive regulation of multicellular organismal process GO:0051240 387 0.035
regulation of signal transduction GO:0009966 318 0.034
Rat
learning or memory GO:0007611 90 0.034
cellular amine metabolic process GO:0044106 38 0.034
positive regulation of cellular component organization GO:0051130 200 0.034
regulation of synaptic transmission GO:0050804 141 0.034
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.033
Mouse Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.033
brain development GO:0007420 247 0.033
Zebrafish Mouse
purine containing compound metabolic process GO:0072521 253 0.033
positive regulation of cellular biosynthetic process GO:0031328 295 0.033
Mouse Rat
positive regulation of neurogenesis GO:0050769 165 0.033
central nervous system development GO:0007417 311 0.032
Zebrafish Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.032
Mouse Rat
reproduction GO:0000003 245 0.032
response to metal ion GO:0010038 253 0.031
regulation of transcription dna templated GO:0006355 374 0.031
Mouse Rat
ribose phosphate metabolic process GO:0019693 235 0.031
transcription dna templated GO:0006351 377 0.031
Mouse Rat
tissue development GO:0009888 252 0.031
Mouse Rat
cellular response to oxygen containing compound GO:1901701 386 0.031
positive regulation of nervous system development GO:0051962 178 0.031
organelle organization GO:0006996 266 0.030
positive regulation of neuron projection development GO:0010976 99 0.030
apoptotic process GO:0006915 381 0.030
monovalent inorganic cation transport GO:0015672 172 0.030
positive regulation of developmental process GO:0051094 283 0.030
inorganic cation transmembrane transport GO:0098662 202 0.030
gland development GO:0048732 155 0.030
response to growth factor GO:0070848 189 0.030
Rat
cellular response to nitrogen compound GO:1901699 210 0.030
cellular lipid metabolic process GO:0044255 208 0.029
regulation of phosphorus metabolic process GO:0051174 349 0.029
response to corticosteroid GO:0031960 235 0.029
Rat
regulation of apoptotic process GO:0042981 335 0.029
cellular homeostasis GO:0019725 252 0.029
cellular catabolic process GO:0044248 295 0.029
rna metabolic process GO:0016070 406 0.028
Mouse Rat
regulation of rna metabolic process GO:0051252 391 0.028
Mouse Rat
multicellular organism reproduction GO:0032504 233 0.028
regulation of phosphorylation GO:0042325 248 0.028
positive regulation of cell proliferation GO:0008284 249 0.028
positive regulation of cell projection organization GO:0031346 111 0.028
regulation of secretion by cell GO:1903530 208 0.028
Rat
chemical homeostasis GO:0048878 292 0.028
negative regulation of cellular metabolic process GO:0031324 281 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
catabolic process GO:0009056 351 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.027
organic hydroxy compound metabolic process GO:1901615 115 0.027
regulation of programmed cell death GO:0043067 341 0.027
response to glucocorticoid GO:0051384 223 0.027
Rat
organophosphate catabolic process GO:0046434 148 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
response to peptide GO:1901652 292 0.026
blood circulation GO:0008015 183 0.026
cellular metal ion homeostasis GO:0006875 172 0.025
positive regulation of cell communication GO:0010647 271 0.025
Rat
cellular chemical homeostasis GO:0055082 247 0.025
divalent metal ion transport GO:0070838 132 0.025
mapk cascade GO:0000165 140 0.025
small molecule biosynthetic process GO:0044283 124 0.025
single organism behavior GO:0044708 130 0.025
Zebrafish
positive regulation of cell development GO:0010720 176 0.025
amine metabolic process GO:0009308 38 0.025
gliogenesis GO:0042063 93 0.025
intracellular signal transduction GO:0035556 314 0.024
positive regulation of cell death GO:0010942 184 0.024
regulation of cell proliferation GO:0042127 359 0.024
response to toxic substance GO:0009636 133 0.024
sexual reproduction GO:0019953 148 0.024
negative regulation of cell communication GO:0010648 158 0.024
Rat
cellular response to organonitrogen compound GO:0071417 197 0.024
cellular response to hormone stimulus GO:0032870 247 0.023
Rat
alcohol metabolic process GO:0006066 77 0.023
positive regulation of biosynthetic process GO:0009891 319 0.023
Mouse Rat
positive regulation of gene expression GO:0010628 244 0.023
Mouse Rat
carboxylic acid transport GO:0046942 115 0.023
regulation of hormone levels GO:0010817 187 0.023
Rat
positive regulation of phosphorylation GO:0042327 177 0.023
negative regulation of programmed cell death GO:0043069 183 0.023
ras protein signal transduction GO:0007265 29 0.023
lipid metabolic process GO:0006629 283 0.023
neuronal action potential GO:0019228 35 0.023
response to estradiol GO:0032355 164 0.023
single organism catabolic process GO:0044712 283 0.022
cellular response to endogenous stimulus GO:0071495 377 0.022
Rat
response to estrogen GO:0043627 232 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
calcium ion transport GO:0006816 131 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.021
cognition GO:0050890 92 0.021
response to alkaloid GO:0043279 132 0.021
response to oxygen levels GO:0070482 265 0.021
organic anion transport GO:0015711 132 0.021
cellular response to peptide GO:1901653 133 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
response to carbohydrate GO:0009743 183 0.020
intracellular transport GO:0046907 185 0.020
rna biosynthetic process GO:0032774 380 0.020
Mouse Rat
heart morphogenesis GO:0003007 3 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
regulation of catalytic activity GO:0050790 304 0.020
localization of cell GO:0051674 202 0.020
circulatory system process GO:0003013 183 0.020
protein phosphorylation GO:0006468 345 0.020
single organism organelle organization GO:1902589 180 0.020
monocarboxylic acid metabolic process GO:0032787 152 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
macromolecular complex subunit organization GO:0043933 339 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
Mouse Rat
positive regulation of protein phosphorylation GO:0001934 135 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
regulation of rna biosynthetic process GO:2001141 381 0.019
Mouse Rat
protein complex subunit organization GO:0071822 302 0.019
fatty acid metabolic process GO:0006631 99 0.019
cellular calcium ion homeostasis GO:0006874 160 0.019
regulation of membrane potential GO:0042391 110 0.019
regulation of mapk cascade GO:0043408 116 0.019
single organism carbohydrate metabolic process GO:0044723 118 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
Mouse Rat
regulation of blood circulation GO:1903522 110 0.019
macromolecule localization GO:0033036 252 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
negative regulation of metabolic process GO:0009892 331 0.018
cellular response to acid chemical GO:0071229 75 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
organic substance catabolic process GO:1901575 316 0.018
locomotion GO:0040011 237 0.018
Zebrafish Mouse
amino acid transport GO:0006865 70 0.018
response to peptide hormone GO:0043434 278 0.018
divalent inorganic cation homeostasis GO:0072507 165 0.018
calcium ion transmembrane transport GO:0070588 70 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
Mouse Rat
negative regulation of molecular function GO:0044092 133 0.018
Mouse Rat
cellular nitrogen compound catabolic process GO:0044270 163 0.018
multicellular organismal homeostasis GO:0048871 49 0.018
oxidation reduction process GO:0055114 304 0.017
negative regulation of neurogenesis GO:0050768 78 0.017
signal transduction by phosphorylation GO:0023014 144 0.017
single organism intracellular transport GO:1902582 166 0.017
positive regulation of signal transduction GO:0009967 175 0.017
positive regulation of nucleotide metabolic process GO:0045981 91 0.017
cell motility GO:0048870 202 0.017
female pregnancy GO:0007565 122 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
divalent inorganic cation transport GO:0072511 134 0.017
ribonucleotide catabolic process GO:0009261 136 0.017
carbohydrate homeostasis GO:0033500 75 0.016
nucleotide metabolic process GO:0009117 279 0.016
response to inorganic substance GO:0010035 377 0.016
ion homeostasis GO:0050801 212 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
Mouse Rat
negative regulation of neuron differentiation GO:0045665 62 0.016
aging GO:0007568 241 0.016
peptide secretion GO:0002790 86 0.016
Rat
cellular ketone metabolic process GO:0042180 51 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
Rat
metal ion homeostasis GO:0055065 186 0.016
regulation of calcium ion transport GO:0051924 77 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
muscle system process GO:0003012 115 0.016
positive regulation of signaling GO:0023056 270 0.015
Rat
negative regulation of cell death GO:0060548 229 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
response to transition metal nanoparticle GO:1990267 122 0.015
cation homeostasis GO:0055080 195 0.015
positive regulation of molecular function GO:0044093 230 0.015
transmission of nerve impulse GO:0019226 42 0.015
regulation of purine nucleotide metabolic process GO:1900542 115 0.015
carbohydrate metabolic process GO:0005975 130 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
cellular ion homeostasis GO:0006873 184 0.015
protein homooligomerization GO:0051260 91 0.015
cellular component movement GO:0006928 248 0.015
Zebrafish Mouse
forebrain development GO:0030900 98 0.015
Zebrafish Mouse
hormone secretion GO:0046879 115 0.015
Rat
cellular response to peptide hormone stimulus GO:0071375 120 0.015
neurological system process GO:0050877 219 0.015
regulation of protein metabolic process GO:0051246 289 0.015
chromosome segregation GO:0007059 2 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
Rat
multicellular organism growth GO:0035264 1 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
Rat
spermatogenesis GO:0007283 99 0.014
regulation of cell projection organization GO:0031344 175 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
gamete generation GO:0007276 124 0.014
head development GO:0060322 247 0.014
Zebrafish Mouse
regulation of dendrite development GO:0050773 59 0.014
macromolecular complex assembly GO:0065003 273 0.014
cytoplasmic transport GO:0016482 115 0.014
negative regulation of nervous system development GO:0051961 79 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
regulation of neuron apoptotic process GO:0043523 83 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
positive regulation of transport GO:0051050 245 0.014
Rat
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.014
cell migration GO:0016477 197 0.014
anterior posterior pattern specification GO:0009952 1 0.014
protein complex biogenesis GO:0070271 263 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
Mouse Rat
organonitrogen compound catabolic process GO:1901565 179 0.014
lipid biosynthetic process GO:0008610 128 0.014
heart contraction GO:0060047 57 0.014
positive regulation of secretion by cell GO:1903532 128 0.013
Rat
regeneration GO:0031099 163 0.013
Rat
developmental process involved in reproduction GO:0003006 159 0.013
hormone transport GO:0009914 121 0.013
Rat
purine nucleotide catabolic process GO:0006195 136 0.013
calcium ion homeostasis GO:0055074 162 0.013
protein complex assembly GO:0006461 263 0.013
response to wounding GO:0009611 254 0.013
Rat
negative regulation of cell development GO:0010721 82 0.013
positive regulation of cell migration GO:0030335 96 0.013
cyclic nucleotide metabolic process GO:0009187 80 0.013
response to nutrient levels GO:0031667 370 0.013
organic hydroxy compound transport GO:0015850 77 0.013
response to monosaccharide GO:0034284 159 0.013
hormone metabolic process GO:0042445 69 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.013
cellular response to stress GO:0033554 269 0.013
Rat
peptidyl amino acid modification GO:0018193 126 0.012
positive regulation of kinase activity GO:0033674 77 0.012
response to glucose GO:0009749 136 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
camp metabolic process GO:0046058 63 0.012
axon ensheathment GO:0008366 40 0.012
respiratory gaseous exchange GO:0007585 4 0.012
sequestering of calcium ion GO:0051208 8 0.012
negative regulation of developmental process GO:0051093 125 0.012
male gamete generation GO:0048232 99 0.012
cell adhesion GO:0007155 110 0.012
organic acid biosynthetic process GO:0016053 83 0.012
sequestering of metal ion GO:0051238 9 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
Mouse Rat
regulation of muscle system process GO:0090257 79 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
peptide transport GO:0015833 97 0.011
Rat
regulation of metal ion transport GO:0010959 118 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
regulation of homeostatic process GO:0032844 101 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
nucleotide catabolic process GO:0009166 139 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
glial cell differentiation GO:0010001 65 0.011
response to cocaine GO:0042220 39 0.011
regulation of insulin secretion GO:0050796 65 0.011
Rat
mechanoreceptor differentiation GO:0042490 2 0.011
gtp metabolic process GO:0046039 72 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
amide transport GO:0042886 105 0.011
Rat
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.011
positive regulation of protein modification process GO:0031401 142 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
regulation of blood pressure GO:0008217 83 0.011
cell cycle GO:0007049 101 0.011
heterocycle catabolic process GO:0046700 167 0.011
negative regulation of gene expression GO:0010629 199 0.011
immune system process GO:0002376 204 0.011
response to ethanol GO:0045471 162 0.011
response to hexose GO:0009746 144 0.011
regulation of protein modification process GO:0031399 194 0.011
multicellular organismal signaling GO:0035637 44 0.011
response to camp GO:0051591 91 0.011
regulation of ion homeostasis GO:2000021 63 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
action potential GO:0001508 54 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
growth GO:0040007 165 0.011
Mouse
rho protein signal transduction GO:0007266 11 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
cardiovascular system development GO:0072358 134 0.011
response to extracellular stimulus GO:0009991 380 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
response to radiation GO:0009314 137 0.011
Zebrafish
inner ear receptor cell differentiation GO:0060113 2 0.011
circulatory system development GO:0072359 134 0.010
organonitrogen compound biosynthetic process GO:1901566 167 0.010
heart process GO:0003015 57 0.010
guanosine containing compound catabolic process GO:1901069 71 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
rhythmic process GO:0048511 156 0.010
regulation of peptide secretion GO:0002791 82 0.010
Rat
positive regulation of protein metabolic process GO:0051247 178 0.010
sodium ion transport GO:0006814 82 0.010
positive regulation of cell motility GO:2000147 97 0.010
single organism cellular localization GO:1902580 102 0.010
axis specification GO:0009798 4 0.010
response to purine containing compound GO:0014074 126 0.010
positive regulation of blood circulation GO:1903524 65 0.010
hepaticobiliary system development GO:0061008 90 0.010
negative regulation of transport GO:0051051 136 0.010
heart development GO:0007507 72 0.010
erk1 and erk2 cascade GO:0070371 48 0.010
anion transmembrane transport GO:0098656 77 0.010
regulation of ras protein signal transduction GO:0046578 45 0.010

Lhx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
sensory system disease DOID:0050155 0 0.013
central nervous system disease DOID:331 0 0.010