Rattus norvegicus

0 known processes

Hspb8

heat shock protein B8

(Aliases: MGC72354,Hsp22,Cryac)

Hspb8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to inorganic substance GO:0010035 377 0.182
Rat
apoptotic process GO:0006915 381 0.165
Rat
regulation of apoptotic process GO:0042981 335 0.113
Rat
negative regulation of apoptotic process GO:0043066 181 0.099
Rat
cellular response to stress GO:0033554 269 0.093
Rat
organelle organization GO:0006996 266 0.087
Rat
macromolecular complex subunit organization GO:0043933 339 0.086
regulation of programmed cell death GO:0043067 341 0.081
Rat
muscle system process GO:0003012 115 0.076
Rat
cardiovascular system development GO:0072358 134 0.074
cellular protein localization GO:0034613 122 0.073
response to other organism GO:0051707 220 0.071
Fly
cellular component biogenesis GO:0044085 368 0.071
regulation of cellular protein metabolic process GO:0032268 267 0.069
protein complex assembly GO:0006461 263 0.069
single organism organelle organization GO:1902589 180 0.068
Rat
regulation of cellular component organization GO:0051128 368 0.067
Rat
cation transport GO:0006812 382 0.064
blood circulation GO:0008015 183 0.062
regulation of phosphorus metabolic process GO:0051174 349 0.062
anatomical structure morphogenesis GO:0009653 298 0.061
Fly
regulation of cell proliferation GO:0042127 359 0.061
regulation of protein metabolic process GO:0051246 289 0.058
protein complex subunit organization GO:0071822 302 0.058
programmed cell death GO:0012501 392 0.056
Rat
circulatory system development GO:0072359 134 0.056
cellular component assembly GO:0022607 360 0.056
reproductive process GO:0022414 372 0.054
response to decreased oxygen levels GO:0036293 237 0.054
Fly
regulation of phosphate metabolic process GO:0019220 349 0.052
cellular response to oxygen containing compound GO:1901701 386 0.051
intracellular signal transduction GO:0035556 314 0.050
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.050
regulation of phosphorylation GO:0042325 248 0.049
circulatory system process GO:0003013 183 0.049
signal transduction by phosphorylation GO:0023014 144 0.049
Rat
regulation of catalytic activity GO:0050790 304 0.049
regulation of molecular function GO:0065009 398 0.049
positive regulation of cell proliferation GO:0008284 249 0.049
response to estrogen GO:0043627 232 0.048
Rat
macromolecular complex assembly GO:0065003 273 0.048
negative regulation of cell death GO:0060548 229 0.048
Rat
protein phosphorylation GO:0006468 345 0.048
regulation of ion transport GO:0043269 245 0.047
protein localization GO:0008104 191 0.047
establishment of protein localization GO:0045184 141 0.045
positive regulation of cellular component organization GO:0051130 200 0.044
membrane organization GO:0061024 94 0.043
cell projection organization GO:0030030 302 0.042
response to nutrient levels GO:0031667 370 0.041
Fly
response to metal ion GO:0010038 253 0.041
cellular macromolecule localization GO:0070727 122 0.041
negative regulation of cellular component organization GO:0051129 83 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.040
locomotion GO:0040011 237 0.040
actin filament based process GO:0030029 86 0.040
rna biosynthetic process GO:0032774 380 0.039
response to oxygen levels GO:0070482 265 0.039
Fly
protein complex biogenesis GO:0070271 263 0.038
response to reactive oxygen species GO:0000302 120 0.038
Rat
regulation of protein localization GO:0032880 81 0.038
transcription from rna polymerase ii promoter GO:0006366 252 0.037
rna metabolic process GO:0016070 406 0.037
negative regulation of cellular metabolic process GO:0031324 281 0.037
Rat
positive regulation of response to stimulus GO:0048584 285 0.037
regulation of rna metabolic process GO:0051252 391 0.037
response to hydrogen peroxide GO:0042542 89 0.036
Rat
cellular response to reactive oxygen species GO:0034614 55 0.036
response to biotic stimulus GO:0009607 226 0.035
Fly
positive regulation of transport GO:0051050 245 0.033
homeostatic process GO:0042592 331 0.033
positive regulation of biosynthetic process GO:0009891 319 0.033
regulation of system process GO:0044057 208 0.032
Rat
multi organism reproductive process GO:0044703 262 0.032
regulation of signal transduction GO:0009966 318 0.032
cellular response to endogenous stimulus GO:0071495 377 0.031
cellular response to hormone stimulus GO:0032870 247 0.031
regulation of protein modification process GO:0031399 194 0.031
neuron differentiation GO:0030182 368 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.031
regulation of protein phosphorylation GO:0001932 183 0.031
positive regulation of protein phosphorylation GO:0001934 135 0.031
protein transport GO:0015031 132 0.031
metal ion transport GO:0030001 289 0.030
response to extracellular stimulus GO:0009991 380 0.030
Fly
cellular component movement GO:0006928 248 0.030
cellular catabolic process GO:0044248 295 0.030
positive regulation of phosphorus metabolic process GO:0010562 262 0.030
positive regulation of phosphate metabolic process GO:0045937 262 0.029
cellular response to organonitrogen compound GO:0071417 197 0.029
muscle contraction GO:0006936 88 0.029
Rat
response to bacterium GO:0009617 200 0.029
Fly
negative regulation of cell proliferation GO:0008285 119 0.029
multi multicellular organism process GO:0044706 138 0.029
vesicle mediated transport GO:0016192 181 0.028
negative regulation of programmed cell death GO:0043069 183 0.028
Rat
positive regulation of protein modification process GO:0031401 142 0.028
positive regulation of molecular function GO:0044093 230 0.028
positive regulation of gene expression GO:0010628 244 0.028
regulation of neuron death GO:1901214 115 0.028
cell migration GO:0016477 197 0.027
positive regulation of phosphorylation GO:0042327 177 0.027
ribonucleotide metabolic process GO:0009259 231 0.027
positive regulation of protein metabolic process GO:0051247 178 0.027
cellular response to organic cyclic compound GO:0071407 202 0.027
macromolecule localization GO:0033036 252 0.027
positive regulation of cellular protein metabolic process GO:0032270 167 0.027
calcium ion transport GO:0006816 131 0.026
regulation of kinase activity GO:0043549 117 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.026
cellular amino acid metabolic process GO:0006520 107 0.026
regulation of calcium ion transport GO:0051924 77 0.026
transmembrane transport GO:0055085 412 0.025
response to hypoxia GO:0001666 231 0.025
Fly
regulation of metal ion transport GO:0010959 118 0.025
actin cytoskeleton organization GO:0030036 73 0.024
negative regulation of gene expression GO:0010629 199 0.024
neuron death GO:0070997 127 0.024
cellular response to nitrogen compound GO:1901699 210 0.024
regulation of nervous system development GO:0051960 264 0.024
secretion GO:0046903 307 0.024
cellular amine metabolic process GO:0044106 38 0.024
regulation of cell migration GO:0030334 128 0.023
regulation of cell development GO:0060284 263 0.023
regulation of anatomical structure size GO:0090066 135 0.023
single organism catabolic process GO:0044712 283 0.022
positive regulation of transcription dna templated GO:0045893 197 0.022
single organism reproductive process GO:0044702 297 0.022
central nervous system development GO:0007417 311 0.022
regulation of transcription dna templated GO:0006355 374 0.022
cellular response to external stimulus GO:0071496 118 0.022
response to vitamin GO:0033273 131 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
regulation of cell projection organization GO:0031344 175 0.022
cation transmembrane transport GO:0098655 263 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.022
gastrulation GO:0007369 2 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
cellular response to peptide hormone stimulus GO:0071375 120 0.021
regulation of multicellular organismal development GO:2000026 376 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
cellular response to oxidative stress GO:0034599 76 0.021
ion transmembrane transport GO:0034220 365 0.021
catabolic process GO:0009056 351 0.021
transcription dna templated GO:0006351 377 0.021
cell motility GO:0048870 202 0.021
response to external biotic stimulus GO:0043207 221 0.021
Fly
cellular ketone metabolic process GO:0042180 51 0.021
regulation of membrane potential GO:0042391 110 0.020
single organism intracellular transport GO:1902582 166 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
wound healing GO:0042060 122 0.020
response to estradiol GO:0032355 164 0.020
Rat
cell growth GO:0016049 104 0.020
Rat
organic substance catabolic process GO:1901575 316 0.020
single organism biosynthetic process GO:0044711 342 0.020
amine metabolic process GO:0009308 38 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
negative regulation of transport GO:0051051 136 0.020
anatomical structure formation involved in morphogenesis GO:0048646 83 0.020
multicellular organism reproduction GO:0032504 233 0.020
neuron projection development GO:0031175 273 0.019
positive regulation of secretion GO:0051047 140 0.019
negative regulation of metabolic process GO:0009892 331 0.019
Rat
regulation of neuron differentiation GO:0045664 208 0.019
cellular response to lipid GO:0071396 201 0.019
response to nutrient GO:0007584 248 0.019
regulation of secretion GO:0051046 224 0.019
organic acid metabolic process GO:0006082 292 0.019
oxoacid metabolic process GO:0043436 290 0.019
response to peptide GO:1901652 292 0.019
negative regulation of signaling GO:0023057 157 0.019
intracellular transport GO:0046907 185 0.019
cytoskeleton organization GO:0007010 111 0.019
Rat
regulation of muscle system process GO:0090257 79 0.019
Rat
cytokine production GO:0001816 61 0.018
neuron apoptotic process GO:0051402 88 0.018
neuronal action potential GO:0019228 35 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
blood vessel development GO:0001568 69 0.018
negative regulation of cell communication GO:0010648 158 0.018
cellular response to peptide GO:1901653 133 0.018
regulation of transferase activity GO:0051338 123 0.018
carboxylic acid metabolic process GO:0019752 289 0.018
divalent inorganic cation transport GO:0072511 134 0.018
positive regulation of cell communication GO:0010647 271 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
response to mechanical stimulus GO:0009612 134 0.018
protein oligomerization GO:0051259 191 0.018
cold acclimation GO:0009631 1 0.018
Fly
organophosphate metabolic process GO:0019637 370 0.018
apoptotic mitochondrial changes GO:0008637 10 0.018
nucleotide metabolic process GO:0009117 279 0.017
response to molecule of bacterial origin GO:0002237 194 0.017
regulation of neurogenesis GO:0050767 247 0.017
regulation of rna biosynthetic process GO:2001141 381 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
cell type specific apoptotic process GO:0097285 134 0.017
cytoplasmic transport GO:0016482 115 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
regulation of mapk cascade GO:0043408 116 0.017
reproduction GO:0000003 245 0.017
reactive oxygen species metabolic process GO:0072593 37 0.017
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
regulation of muscle contraction GO:0006937 53 0.017
Rat
positive regulation of developmental process GO:0051094 283 0.017
endocytosis GO:0006897 84 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
cellular homeostasis GO:0019725 252 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
aging GO:0007568 241 0.017
Rat Fly
regulation of blood pressure GO:0008217 83 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
ion homeostasis GO:0050801 212 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
negative regulation of protein metabolic process GO:0051248 114 0.017
regulation of cell differentiation GO:0045595 320 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
nucleic acid templated transcription GO:0097659 379 0.016
regulation of neuron apoptotic process GO:0043523 83 0.016
response to wounding GO:0009611 254 0.016
regulation of immune system process GO:0002682 123 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
positive regulation of cell death GO:0010942 184 0.016
response to lipopolysaccharide GO:0032496 191 0.016
protein localization to organelle GO:0033365 57 0.016
proteolysis GO:0006508 175 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
smooth muscle cell proliferation GO:0048659 77 0.016
response to glucocorticoid GO:0051384 223 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
localization of cell GO:0051674 202 0.016
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.016
cell cycle GO:0007049 101 0.016
angiogenesis GO:0001525 53 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.016
regulation of cell growth GO:0001558 85 0.015
Rat
positive regulation of cell differentiation GO:0045597 217 0.015
single organism membrane organization GO:0044802 74 0.015
regulation of smooth muscle cell proliferation GO:0048660 75 0.015
regulation of neuron projection development GO:0010975 161 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
cellular chemical homeostasis GO:0055082 247 0.015
response to radiation GO:0009314 137 0.015
head development GO:0060322 247 0.015
divalent metal ion transport GO:0070838 132 0.015
nucleocytoplasmic transport GO:0006913 48 0.015
growth GO:0040007 165 0.015
Rat
defense response GO:0006952 194 0.015
Fly
negative regulation of growth GO:0045926 37 0.015
Rat
cell projection morphogenesis GO:0048858 123 0.015
regulation of growth GO:0040008 105 0.015
Rat
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
regulation of establishment of protein localization GO:0070201 69 0.015
maintenance of location GO:0051235 17 0.015
response to heat GO:0009408 60 0.015
Rat Fly
gamete generation GO:0007276 124 0.015
negative regulation of molecular function GO:0044092 133 0.015
negative regulation of cell development GO:0010721 82 0.015
female pregnancy GO:0007565 122 0.015
vasculature development GO:0001944 70 0.015
regulation of angiogenesis GO:0045765 39 0.015
positive regulation of kinase activity GO:0033674 77 0.015
regulation of protein transport GO:0051223 68 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
salivary gland development GO:0007431 3 0.014
cellular macromolecular complex assembly GO:0034622 58 0.014
regulation of vasculature development GO:1901342 44 0.014
sexual reproduction GO:0019953 148 0.014
cellular response to alcohol GO:0097306 87 0.014
multicellular organismal signaling GO:0035637 44 0.014
mapk cascade GO:0000165 140 0.014
Rat
neurological system process GO:0050877 219 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
regulation of proteolysis GO:0030162 66 0.014
heart development GO:0007507 72 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
response to acid chemical GO:0001101 222 0.014
tissue development GO:0009888 252 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
organic acid transport GO:0015849 116 0.014
axis specification GO:0009798 4 0.014
muscle cell proliferation GO:0033002 84 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
calcium ion homeostasis GO:0055074 162 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
regulation of cellular component movement GO:0051270 150 0.014
negative regulation of rna biosynthetic process GO:1902679 118 0.013
nucleotide catabolic process GO:0009166 139 0.013
gland development GO:0048732 155 0.013
negative regulation of signal transduction GO:0009968 83 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
protein homooligomerization GO:0051260 91 0.013
transmission of nerve impulse GO:0019226 42 0.013
protein maturation GO:0051604 68 0.013
regulation of hormone levels GO:0010817 187 0.013
regulation of proteasomal protein catabolic process GO:0061136 4 0.013
positive regulation of signaling GO:0023056 270 0.013
positive regulation of signal transduction GO:0009967 175 0.013
regulation of cellular localization GO:0060341 263 0.013
positive regulation of ion transport GO:0043270 94 0.013
positive regulation of protein kinase activity GO:0045860 73 0.013
cellular response to steroid hormone stimulus GO:0071383 93 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
purine containing compound metabolic process GO:0072521 253 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
anterior posterior pattern specification GO:0009952 1 0.013
regulation of body fluid levels GO:0050878 90 0.013
response to ethanol GO:0045471 162 0.013
brain development GO:0007420 247 0.012
tube development GO:0035295 89 0.012
single organism cellular localization GO:1902580 102 0.012
regeneration GO:0031099 163 0.012
negative regulation of neuron differentiation GO:0045665 62 0.012
negative regulation of protein maturation GO:1903318 47 0.012
secretion by cell GO:0032940 248 0.012
cell part morphogenesis GO:0032990 123 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
response to cytokine GO:0034097 215 0.012
positive regulation of transferase activity GO:0051347 81 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
mesoderm development GO:0007498 2 0.012
response to growth factor GO:0070848 189 0.012
regulation of catabolic process GO:0009894 113 0.012
striated muscle cell development GO:0055002 26 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
regulation of protein kinase activity GO:0045859 105 0.012
dephosphorylation GO:0016311 98 0.012
striated muscle tissue development GO:0014706 58 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
fertilization GO:0009566 3 0.012
metal ion homeostasis GO:0055065 186 0.012
regulation of vesicle mediated transport GO:0060627 81 0.012
response to carbohydrate GO:0009743 183 0.012
heterocycle catabolic process GO:0046700 167 0.012
purine nucleoside triphosphate catabolic process GO:0009146 122 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
regulation of locomotion GO:0040012 148 0.011
striated muscle contraction GO:0006941 44 0.011
positive regulation of protein transport GO:0051222 41 0.011
positive regulation of nervous system development GO:0051962 178 0.011
action potential GO:0001508 54 0.011
behavior GO:0007610 205 0.011
chemical homeostasis GO:0048878 292 0.011
muscle structure development GO:0061061 87 0.011
positive regulation of cell development GO:0010720 176 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
nucleoside metabolic process GO:0009116 179 0.011
potassium ion transport GO:0006813 97 0.011
carboxylic acid transport GO:0046942 115 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
Rat
positive regulation of intracellular signal transduction GO:1902533 138 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
dna metabolic process GO:0006259 96 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
muscle cell differentiation GO:0042692 52 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
response to cadmium ion GO:0046686 35 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
actin mediated cell contraction GO:0070252 12 0.011
negative regulation of ion transport GO:0043271 51 0.011
stress activated mapk cascade GO:0051403 35 0.011
Rat
neuron development GO:0048666 286 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
response to amino acid GO:0043200 75 0.011
response to oxidative stress GO:0006979 186 0.010
Rat Fly
monocarboxylic acid metabolic process GO:0032787 152 0.010
regulation of response to external stimulus GO:0032101 106 0.010
regulation of cytokine production GO:0001817 56 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
cellular carbohydrate metabolic process GO:0044262 72 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.010
positive regulation of endothelial cell migration GO:0010595 4 0.010
formation of primary germ layer GO:0001704 1 0.010
regulation of endocytosis GO:0030100 42 0.010
organonitrogen compound catabolic process GO:1901565 179 0.010
response to corticosteroid GO:0031960 235 0.010
muscle tissue development GO:0060537 58 0.010
aromatic compound catabolic process GO:0019439 168 0.010
response to temperature stimulus GO:0009266 94 0.010
Rat Fly
negative regulation of neuron death GO:1901215 69 0.010
cellular response to cytokine stimulus GO:0071345 127 0.010
small gtpase mediated signal transduction GO:0007264 36 0.010
response to light stimulus GO:0009416 52 0.010

Hspb8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.073
Human
musculoskeletal system disease DOID:17 0 0.073
myopathy DOID:423 0 0.043
muscular disease DOID:0080000 0 0.043
muscle tissue disease DOID:66 0 0.043
cardiovascular system disease DOID:1287 0 0.022
nervous system disease DOID:863 0 0.018
Human
muscular dystrophy DOID:9884 0 0.017
heart disease DOID:114 0 0.014
cardiomyopathy DOID:0050700 0 0.014
dilated cardiomyopathy DOID:12930 0 0.012
intrinsic cardiomyopathy DOID:0060036 0 0.012
sensory system disease DOID:0050155 0 0.011